Deep Origin
Posted 1mo ago

Staff Full Stack/Back End Engineer (NodeJS+React)

Deep Origin
South San Francisco, California, United States
HybridFull Time
Responsibilities
  • building functionality
  • designing architecture
  • integrating partners
Requirements
  • 10+ years building scalable distributed systems
  • 5+ years with React/TypeScript/JavaScript/NodeJS
  • Experience with Postgres
  • MongoDB
  • Kubernetes
  • Cloud infra
  • Multi-tenant systems
  • Authorized to work in the U.S
  • Strong system design skills
Technical tools mentioned
ReactTypeScriptJavaScriptNodeJSPostgresMongoDBKubernetes

Job description

About Deep Origin

Led by Michael Antonov, a co-founder of Oculus, and well-funded by Formic Ventures, Deep Origin is poised to reinvent the way scientists work and life science innovations come to life. We see a future largely free of diseases, with a 150-year lifespan being the norm. To get there, we are building an operating system for science, enabling scientists to be more productive and to bring tomorrow's ideas to life quickly and at a reasonable cost.

Role Description

We are seeking a talented and experienced Staff Engineer to join our dynamic team. You will be a key member of the software engineering team, building our key functionality and integrating with key partners. You will have ownership in key software feature areas and their architectural design, as well as software implementation with a high level of independence and impact. You will work closely with cross-functional teams to create robust, user-friendly applications that drive the efficiency and effectiveness of biologists and researchers in their scientific endeavors.

Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

Requirements

  • 10+ years of experience designing, building, and operating complex, highly scalable, distributed applications and systems
  • 5+ years of hands-on software development experience with React/TypeScript/JavaScript/NodeJS
  • Experience with both relational databases (e.g., Postgres) and NOSQL (e.g., MongoDB)
  • Knowledge of Kubernetes and Cloud infrastructure/deployment tools (specifically with cluster operations and operators)
  • Has built platforms from an early stage
  • Has scaled platforms to handle many users (10,000+ DAU)
  • Has extensive system-design experience
  • Has experience designing systems with complex datasets/relations
  • Has experience working with distributed systems/platforms
  • Thinks about architecture first and how the code fits in second
  • Has experience working with/implementing a multi-tenant system
  • Systematic problem-solving approach, coupled with a strong sense of ownership and drive
  • Ability to work both independently and on a team
  • Experience working in high-energy startups with fast product delivery mechanisms
  • Must work onsite at least 3 days a week.

Benefits

  • Opportunity to collaborate with highly talented teams
  • Competitive compensation package with meaningful equity
  • Comprehensive health, dental, and vision coverage
  • Annual team gatherings and company events.

About Deep Origin

Platform for scientific simulation and drug discovery research.

Year founded
2022
Employees
77
Organization type
Private
Latest investment
Raised $25.50M Series B (2024) — led by Formic Ventures
Headquarters
US

Similar jobs

Full Stack Engineer roles near South San Francisco, California
2d
Save
Mark Applied
Hide
Senior Full Stack Engineer
South San Francisco or North America
OnsiteFull Time
Gritt Robotics
Gritt Robotics: Developing autonomous robots to automate outdoor construction tasks.
6+ YOERequires 6+ years building production cloud applications and backend systems, Python and TypeScript/JavaScript, React or similar, data infrastructure, cloud deployment, and experience with agentic AI systems.
Python, TypeScript, JavaScript, React, Rust, Go, AWS, GCP, Azure
2d
Save
Mark Applied
Hide
Senior Full Stack Engineer - BitGo Labs
Palo Alto, California, United States
$200k-$240k/yr OnsiteFull Time
BitGo
BitGoNYSE: BTGO: Provides secure infrastructure for institutional digital asset management.
5+ YOE5+ years of full-stack engineering experience, including web frontend, API and service design, data modeling, and cloud deployment. Requires zero-to-one product experience, AI tooling expertise, and crypto curiosity.
AI, API
2d
Save
Mark Applied
Hide
Founding Full Stack Engineer
San Francisco or United States
$135k-$155k/yr RemoteFull Time
Clera
Clera: AI talent agent matching professionals with high-growth startup roles
5+ YOE5+ years building production SaaS products; strong TypeScript, React, and server-side JavaScript skills; backend architecture, enterprise authentication, AI workflows, and early-stage ownership experience.
TypeScript, React, JavaScript, Next.js, PostgreSQL, Supabase, Vercel, Amazon Web Services (AWS), Amazon S3, SAML, RBAC, CI/CD, SSO, HRIS, EAP
2d
Save
Mark Applied
Hide
Full Stack Engineer
United States or San Francisco or New York City or Los Angeles or Boston or Seattle or Washington or San Diego or Chicago or Austin or Dallas or Portland or Denver or Philadelphia or Baltimore or Sacramento or Minneapolis or Miami or Atlanta or Phoenix or Orlando or Las Vegas or Salt Lake City or Madison or Birmingham or San Antonio or Spokane or Toronto
$115k-$195k/yr HybridFull Time
Roo
Roo: Digital marketplace connecting veterinary professionals with animal hospital shifts.
2+ YOE2–4 years of software engineering experience; proficiency in TypeScript/JavaScript, React Native, Node, Express, React, AWS, relational databases, and SQL. Strong communication and teamwork skills; computer science degree preferred.
TypeScript, JavaScript, React Native, Jest, Cypress, Node, Express, React, AWS, SQL, CI/CD
2d
Save
Mark Applied
Hide
Senior Full Stack Engineer, Cloud Platform
Palo Alto, California, United States
$175k-$205k/yr OnsiteFull Time
ALSO
ALSO: Developing vertically integrated small electric vehicles for urban mobility.
7+ YOE7+ years building production backend services; expertise in TypeScript/Node.js, React, AWS, APIs, data modeling, event-driven architecture, containers, security, testing, and production operations.
TypeScript, Node.js, React, AWS, REST, GraphQL, gRPC, Kafka, SQS, SNS, Redis, Docker, Kubernetes, OAuth2, OIDC, JWT, mTLS, Go, WebSockets, WebRTC, MQTT, CoAP, Terraform, Figma
3d
Save
Mark Applied
Hide
Sr. II Full Stack Engineer, Cloud Native - AI Detection and Response (AIDR) (Hybrid, Sunnyvale)
Sunnyvale, California, United States
$160k-$250k/yr HybridFull Time
CrowdStrike
CrowdStrikeNASDAQ: CRWD: Provides cloud-native endpoint protection and cybersecurity services.
2+ YOERequires 2–5 years of production application development experience, React.js, JavaScript/HTML/CSS, Go or object-oriented languages, REST and GraphQL APIs, CI/CD, automated testing, Git, and CJIS clearance eligibility.
React.js, JavaScript, HTML, CSS, Go, REST, GraphQL, CI/CD, Git
3d
Save
Mark Applied
Hide
Full Stack Engineer
Pleasanton, California, United States
$100k-$115k/yr OnsiteFull Time
Tata Consultancy Services
Tata Consultancy ServicesNational Stock Exchange of India: TCS: Global provider of IT services, consulting, and business solutions.
7+ YOERequires 7+ years of full-stack development experience, a bachelor's in computer science, and expertise in Node.js, React.js, REST APIs, Azure, AKS, PostgreSQL, SQL, and Databricks.
Node.js, React.js, REST APIs, Microsoft Azure, Azure Kubernetes Service (AKS), PostgreSQL, SQL, Databricks, Agile, Scrum
3d
Save
Mark Applied
Hide
Senior / Staff Full Stack Engineer – AI
Mountain View, California, United States
HybridContract
Delan Associates
Delan Associates: Provides engineering and professional services to government agencies.
8+ YOE8+ years of experience building production AI or agentic applications with full-stack engineering skills in React, TypeScript, Python, Go, Java, AWS, Kubernetes, and distributed systems.
React, TypeScript, Python, Go, Java, LangGraph, LangChain, Claude Agent SDK, AWS, Amazon EKS, Amazon EC2, Amazon S3, Amazon VPC, Kubernetes, Helm, GitOps, AWS CDK, CloudFormation, WebSockets, Claude, Cursor