14 associate principal scientist jobs at 9 companies in California

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Associate Principal Scientist, Innovation
El Segundo, California, United States
$116k-$174k/yr HybridFull Time
Liquid I.V.
Liquid I.V.: Functional hydration selling electrolyte drink mixes to everyday consumers.
6+ YOEMaster's in nutrition/exercise physiology or related,6+ years R&D/innovation experience in CPG or supplements,expertise with dietary supplement ingredients,supporting concept-to-commercialization,AI tools and cross-functional work.
Microsoft Office, Citation Managers, PubMed, AI tools and platforms
6d
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Associate Principal Scientist, Clinical Research
Rahway or Boston or West Point or South San Francisco
$142k-$224k/yr HybridFull Time
MSD
MSDNYSE: MRK: We use leading-edge science to save and improve lives.
3+ YOELife sciences degree plus 3–11+ years related experience, including Phase 1 or Phase 2–3 clinical trials. Requires vaccine program management, GCP/ICH knowledge, scientific writing, project leadership, data evaluation, and mentoring.
2mo
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Associate Principal Scientist, Immunology Discovery
San Diego, California, United States
$142k-$224k/yr OnsiteFull Time
Merck Research Laboratories
Merck Research LaboratoriesNYSE: MRK: Merck’s research and development division creates medicines and vaccines for patients worldwide.
5+ YOEPhD with 5+ years in immunology/cell biology, strong experience in immunology assays and preclinical models, proficiency with Excel/Prism/FlowJo, leadership and cross-functional program experience.
Microsoft Excel, Prism (GraphPad), FlowJo, Meso Scale Discovery, RT-PCR
3w
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Principal Scientist / Associate Director – Translational Biology
South San Francisco, California, United States
$175k-$200k/yr OnsiteFull Time
Dualitas Therapeutics
Dualitas Therapeutics: Biotechnology developing bispecific antibody therapies for immune and inflammatory diseases.
8+ YOEPhD preferred in immunology, pharmacology, or related field; 8+ years relevant industry experience; expertise in autoimmune or inflammatory programs, pharmacology studies, CRO management, immunology, and scientific leadership.
3d
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Associate Principal Scientist, Discovery Oncology, Reverse Translation
South San Francisco, California, United States
$160k-$251k/yr OnsiteFull Time
MSD
MSDNYSE: MRK: We use leading-edge science to save and improve lives.
4+ YOEPh.D. in a relevant STEM field plus 4+ years postdoctoral or relevant experience, or MS with 7+ years, or BS with 11+ years; expertise in oncology, cell assays, flow cytometry, and molecular biology.
Multiparametric flow cytometry, RT-PCR
2d
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Principal Scientist (Associate Director), Reagent Product Development
San Diego, California, United States
$175k-$200k/yr OnsiteFull Time
Quantum-Si
Quantum-SiNasdaq: QSI: Public U.S. biotechnology that develops benchtop single-molecule protein sequencing systems for researchers.
12+ YOE8+ MgmtPhD in a relevant life science field, 12+ years of industry experience including 8+ in product development, protein reagent or sequencing chemistry expertise, and experience leading teams and commercial product launches.
DOE, ISO 13485, FDA QSR, E-Verify
1w
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Principal Associate Scientist - Pharmaceutical Development
South San Francisco, California, United States
$93k-$172k/yr OnsiteFull Time
Genentech
Genentech: U.S.-headquartered biotechnology discovering and developing medicines for people with serious and life-threatening diseases.
2+ YOEBachelor's degree in a relevant engineering or science field and 2+ years of industry experience; requires biopharmaceutical process development, laboratory, analytical, communication, GMP documentation, and regulatory knowledge.
11h
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Principal Associate Scientist, Bioanalytical Science
South San Francisco, California, United States
$110k-$138k/yr OnsiteFull Time
Xaira Therapeutics
Xaira Therapeutics: Private biotechnology using artificial intelligence to discover and develop medicines.
7+ YOEB.S. or M.S. in biochemistry, immunology, analytical chemistry, or related field; 7+ years industry experience; hands-on ligand binding and flow cytometry assays; PK/PD sample analysis; independent troubleshooting.
ELISA, MSD/ECL, flow cytometry
5d
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Associate Principal Bioinformatics Scientist
San Diego, California, United States
$114k-$228k/yr OnsiteFull Time
Abbott
AbbottNYSE: ABT: Global healthcare technology focused on life-changing medical innovations.
9+ YOERequires PhD plus 9+ years in bioinformatics, or equivalent master's/bachelor's experience; 8+ years in molecular diagnostics, medical devices, biotech, or life sciences; statistical methods and genomics expertise.
Microsoft Office, Microsoft Excel, Microsoft Word, Microsoft PowerPoint, SmartSheet, MS Projects, AI, Dev/Ops
5d
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Associate Principal Bioinformatics Scientist
San Diego or La Jolla
$114k-$228k/yr OnsiteFull Time
Abbott
AbbottNYSE: ABT: Global healthcare technology focused on life-changing medical innovations.
9+ YOEPhD plus 9+ years of bioinformatics experience, or equivalent master's/bachelor's experience; 8+ years in molecular diagnostics, medical devices, biotech, or life sciences; expertise in genomics, NGS, statistical methods, and product development.
Microsoft Excel, Microsoft Word, Microsoft PowerPoint, SmartSheet, MS Projects, AI, Dev/Ops
1mo
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Principal Associate, Data Scientist - Emerging ML
McLean or San Jose or New York City
$162k-$201k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: A technology-driven bank providing diverse financial services.
3+ YOEQuantitative bachelor's degree plus 5 years, master's or quantitative MBA plus 3 years, or PhD; 3+ years in data analytics, machine learning, and SQL, with Python, Scala, or R experience.
Python, Scala, R, SQL, Spark, AWS
1mo
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Principal Associate, Data Scientist - Emerging ML
McLean or San Jose or New York City
$162k-$201k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: A technology-driven bank providing diverse financial services.
3+ YOEQuantitative bachelor's degree plus 5 years, master's or quantitative MBA plus 3 years, or PhD; preferred experience includes Python, Scala, R, machine learning, and SQL.
Python, Scala, R, Spark, AWS, SQL
1mo
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Principal Associate, Data Scientist - Emerging ML
McLean or New York City or San Jose
$162k-$201k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: A technology-driven bank providing diverse financial services.
5+ YOEAdvanced degree in quantitative field plus relevant analytics experience; 3–5+ years of data science experience; proficiency in Python/Scala/R, SQL, Spark, AWS; strong statistical and ML expertise.
Python, Scala, R, Spark, AWS, SQL
1mo
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Principal Scientist / Associate Director, Agentic AI Research for Materials Science
Cambridge or San Francisco
$288k-$420k/yr OnsiteFull Time
Lila Sciences
Lila Sciences: Builds AI and autonomous labs for scientific discovery.
5+ YOEPhD with 5+ years post-PhD research and applied ML experience; track record building agentic systems; expertise in LLMs, reasoning, multimodal data, materials science grounding; Python proficiency; leadership and communication skills.
Python, LLMs, HPC