8 autonomous systems engineer jobs at 6 companies in Lancaster, CA

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Mission Systems Engineer
Los Angeles or Altadena
$121k-$169k/yr OnsiteFull Time
Blue Origin: Develops reusable rockets and systems for human spaceflight.
5+ YOEBachelor's in engineering or physics; 5+ years systems engineering; experience leading trade studies; ability to work autonomously; travel up to 25%; US citizen or eligible for authorized US work; ability to obtain Top Secret clearance.
Python, MATLAB, MBSE (Cameo/SysML)
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Senior Systems Software Engineer
Los Angeles or Remote- US
$145k-$195k/yr HybridFull Time
Zoo
Zoo: Develops infrastructure and AI-powered tools for hardware design.
Senior systems, platform, or infrastructure engineering with Rust expertise; strong backend/infrastructure focus; experience with distributed systems, databases, APIs, and IaC; autonomous, proactive, and customer-focused.
Rust, Databases, API design, Distributed systems, Infrastructure as code, Containers, React
3mo
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Senior/Staff ML Systems Engineer
Los Angeles, California, United States
$180k-$200k/yr RemoteFull Time
Quilter
Quilter: Automates printed circuit board layout using physics-driven AI.
5+ YOE5+ years building and operating production ML systems; strong software engineering, autonomous work style, GPU/accelerated workloads experience, data pipelines, CI/CD and orchestration expertise.
GPU, CUDA, Python, Docker, Kubernetes, TensorFlow, PyTorch, MLflow, CI/CD
1mo
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Staff Software Engineer - Growth + Onboarding
San Francisco or New York City or Los Angeles
$210k-$240k/yr HybridFull Time
Pivotal Health
Pivotal Health: AI platform automating healthcare insurance claim disputes for providers.
8+ YOE8+ years backend software engineering experience; strong systems and database instincts; experience owning architecture for production systems; integration experience (EHR/APIs/SFTP) preferred; able to mentor and work autonomously.
EDI (835/837), HL7, FHIR, ICD-10, CPT, Epic, Cerner, SFTP, Python
2w
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Sr. Staff Software Engineer, DUE Experience
Mountain View or Seattle or New York City or Los Angeles or San Francisco or United States
$298k-$368k/yr HybridFull Time
Waymo
Waymo: Autonomous driving technology for ride-hailing and logistics.
10+ YOE10+ years software engineering experience with AI/ML and autonomous agent design, deep expertise integrating LLMs and multi-agent systems, proven technical leadership, and a bachelor's degree or equivalent.
C++, LLMs
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Research Flight Test Engineer - SME
Edwards AFB, California, United States
$170k-$220k/yr OnsiteFull Time
Modern Technology Solutions, Inc.
Modern Technology Solutions, Inc.: Provides engineering, technology, and cybersecurity services for national security.
15+ YOE15+ years in flight test planning/execution; 5–10 years in mission systems/electronics warfare; DoD modification & airworthiness knowledge; AI/ML and autonomous systems experience; leads flight test missions and test planning.
AESARadar, IRST, EO/IR imaging, Radar warning receivers, DoD modification processes, AI/ML, autonomous aircraft systems
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Senior Software Engineer, Cloud Infrastructure
Los Angeles or United States
$145k-$195k/yr HybridFull Time
Zoo
Zoo: Develops infrastructure and AI-powered tools for hardware design.
BS in CS or related field; senior systems/infrastructure experience; Rust proficiency; databases; API design; distributed systems; IaC and container deployments; autonomous, fast-moving work style; automation-oriented.
Rust, Databases, API Design, Distributed Systems, Infrastructure as Code, Kubernetes, Terraform, Docker, AWS
3mo
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Manager, Data Science & Engineering - Title & Launch Management
United States or Los Angeles or Los Gatos
$480k-$750k/yr RemoteFull Time
Netflix
NetflixNASDAQ: NFLX: Provider of global streaming entertainment and video content.
6+ YOE2+ MgmtLead ML/data teams; 6+ years hands‑on ML experience (or 4+ with PhD); 2+ years leading ML teams; Master's (or PhD) in ML/CS; expertise in agentic/autonomous ML systems; strong communication and mentoring skills.