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26 downstream jobs at 16 companies in San Francisco, CA

2mo
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Director, Downstream Process Development
Redwood City, California, United States
OnsiteFull Time
Allakos
Allakos: Clinical-stage biopharmaceutical developing antibody therapies.
15+ YOE8+ Mgmt15+ years in biopharma; 8+ years cross-functional leadership; downstream process development of biologics; tech transfer; PPQ; BLA support; travel up to 10%.
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1w
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Associate Director, Drug Substance Manufacturing – Downstream Process
Brisbane, California, United States
$175k-$210k/yr HybridFull Time
Vera Therapeutics
Vera TherapeuticsNASDAQ: VERA: Develops treatments for serious immunological and autoimmune diseases.
5+ YOEMS (or BS) with substantial biologics downstream experience, 5+ years industry experience (MS) or 8+ years (BS), expertise in downstream unit operations, technology transfer, process validation, GMP and regulatory submissions.
MS Project
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3mo
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Downstream Product Marketing Manager (Union City, CA, US, 94587-1234)
Union City, California, United States
$126k-$155k/yr OnsiteFull Time
Mizuho OSI
Mizuho OSI: Designs and manufactures specialty surgical tables and positioning systems.
5+ YOE5+ years medical device marketing; hospital/B2B marketing to clinicians and admins; orthopedic space experience; digital marketing; strong communication; travel up to 30%
Pardot, Salesforce, Seismic, Marketing Automation, Microsoft Office
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1mo
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Scientist II, Downstream Viral Vector Process Development
Alameda, California, United States
$130k-$150k/yr OnsiteFull Time
GeneFab
GeneFab: Specialized contract manufacturing for advanced cell and gene therapies.
3+ YOEPh.D. (3+ years) or Master’s (5+ years) in chemical/biochemical engineering, biotechnology or related; proven downstream viral vector (AAV, lentiviral) experience, chromatography, filtration/TFF, strong analytical, communication, and regulatory knowledge.
chromatography, filtration, TFF
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1mo
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Field Application Specialist - Downstream Bioprocessing (Bay Area)
San Francisco or California or United States
FieldFull Time
Sartorius
SartoriusXETRA: SRT3: Providing equipment and technologies for biopharmaceutical research and manufacturing.
3+ YOEBachelor's in biological engineering/biotechnology/life sciences, 3+ years downstream bioprocessing (TFF, UF/DF, NFF) experience, product/application expertise, Microsoft Office skills, ability to perform installations, demos, training, and customer troubleshooting; ~40% travel.
Microsoft Office
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Senior Scientist II, Downstream Development (Scale-Up Laboratory Lead)
South San Francisco, California, United States
$110k-$209k/yr OnsiteFull Time
AbbVie
AbbVieNYSE: ABBV: Develops and sells innovative pharmaceutical and biopharmaceutical medicines.
4+ YOEDegree in chemical engineering/biochemistry/chemistry, extensive downstream/purification scale-up and tech transfer experience, AKTA/UNICORN expertise, hands-on chromatography and TFF experience, leadership and technical writing skills.
AKTA Ready, AKTA Ready LX, AKTA Avant, AKTA Pure, UNICORN, AxiChrom, QuickScale, BPG, Allegro, Cytiva, Repligen, AKTA flow kits, TFF flow kits, TFF, HPLC, CE, UV-based quantitation
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3w
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Global Product Manager, Downstream IVL
Santa Clara, California, United States
$114k-$228k/yr OnsiteFull Time
Abbott
AbbottNYSE: ABT: Manufactures medical devices, diagnostics, and nutritional health products.
5+ YOEBachelor's degree (or equivalent), minimum 5 years product/strategic marketing experience in healthcare/medical devices, experience with global launches, strong communication and project management skills, ability to travel up to 25%.
Microsoft PowerPoint, Microsoft Excel
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3w
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Global Product Manager, Downstream IVL
Santa Clara, California, United States
$114k-$228k/yr OnsiteFull Time
Abbott
AbbottNYSE: ABT: Provides medical devices, diagnostics, and science-based nutritional products.
5+ YOEBachelor's degree, minimum 5 years product/marketing experience in healthcare or medical devices, strong strategic, communication, and project management skills; ability to travel up to 25%.
Microsoft PowerPoint, Microsoft Excel
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1w
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Product Manager, Peripheral Downstream - Shockwave Medical
Santa Clara or United States
$109k-$175k/yr RemoteFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Develops and manufactures pharmaceutical drugs and medical devices.
4+ YOEBachelors or equivalent required, MBA preferred; 4+ years product/marketing experience in cardiovascular medtech; experience launching products, KOL engagement, and cross-functional collaboration; up to 30% travel.
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1w
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Product Manager, Peripheral Downstream - Shockwave Medical
Santa Clara, California, United States
$109k-$175k/yr RemoteFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Provides pharmaceutical products and medical technology healthcare solutions.
4+ YOEBachelor’s degree or equivalent; 4+ years product/marketing experience in cardiovascular medtech; experience launching novel products, KOL engagement, cross-functional collaboration, and travel up to 30%.
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2w
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Sr. Data Engineer - Services Special Project
Cupertino, California, United States
OnsiteFull Time
Apple
AppleNASDAQ: AAPL: Designs and sells consumer electronics, software, and online services.
Develop and operate a real-time platform to transform multimodal data into an enriched, searchable foundation for downstream applications.
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6d
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Vice President, Specialty Oncology
Brisbane or California
$330k-$375k/yr RemoteFull Time
CareDx
CareDxNASDAQ: CDNA: Develops diagnostic tests and digital tools for transplant care.
12+ YOEAdvanced degree preferred; 12+ years in oncology, molecular diagnostics, or biopharma; franchise or portfolio leadership; upstream and downstream marketing; medical collaboration; and matrix leadership experience.
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1w
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Principal Scientist, Commercial and Late-Stage Purification Process Development
South San Francisco, California, United States
$159k-$207k/yr OnsiteFull Time
Denali Therapeutics
Denali TherapeuticsNASDAQ: DNLI: Developing medicines for neurodegenerative and lysosomal storage diseases.
10+ YOEPhD plus 10+ years experience in downstream purification, commercial process support, tech transfer, process characterization, and regulatory lifecycle management; expertise with AKTA and antibody characterization.
AKTA
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1mo
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Hunyuan Multimodal Algorithm Researcher Intern(Omni-Modal)
Palo Alto, California, United States
$80k-$125k/yr OnsiteFull Time, Internship
Tencent
TencentHong Kong Stock Exchange: 0700: Multinational technology conglomerate providing internet and entertainment services.
Research and develop omni-modal large models, including data construction, foundational algorithm design, pre-training/SFT/RL optimization, model evaluation, and downstream application exploration.
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2mo
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Associate Director / Director, CMC Process Development
South San Francisco, California, United States
$180k-$250k/yr HybridFull Time
NGM Bio
NGM Bio: Develops biologic medicines for liver and oncologic diseases.
8+ YOEMS or PhD required, 8+ years in upstream/downstream biologics process development and CDMO management, GMP and process characterization expertise, ability to author regulatory documents and lead late-stage development.
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2w
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Senior Technical Application Specialist, Biosafety - West Coast
Burlington or Los Angeles or San Diego or San Francisco
$100k-$167k/yr FieldFull Time
Merck KGaA, Darmstadt, Germany
Merck KGaA, Darmstadt, GermanyFrankfurt Stock Exchange: MRK: A science and technology in healthcare, life sciences, and electronics.
5+ YOEBachelor's degree in a relevant life sciences field, 5+ years of life sciences technical experience with sales or customer-facing work, downstream biopharmaceutical expertise, project management, and 20–30% travel.
aseptic filtration, virus filtration, downstream processing, sterile filtration, project management, Microsoft?
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3w
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Scientist, Drug Discovery
Palo Alto, California, United States
OnsiteFull Time
Transcripta Bio
Transcripta Bio: AI-driven drug discovery platform leveraging high-resolution transcriptomic data.
3+ YOEPhD (3–5+ yrs) or MS (6+ yrs) in relevant field, expertise with iPSC maintenance/differentiation, high-throughput screening and liquid handling, downstream validation assays, ELN documentation, and experimental design.
Hamilton, Tecan, Beckman, Opera Phenix, ImageXpress, ELN, Python, R, Conductor AI
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1mo
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Associate Director, Bioprocess Development
Vacaville, California, United States
$105k-$130k/yr OnsiteFull Time
Oath
Oath: Develops microbial and AI solutions for soil regeneration and agriculture.
5+ YOEPh.D. (or M.S. with extensive experience) and 5+ years in bioprocess development with expertise in SSF and submerged fermentation, downstream processing, scale-up, CRO/CDMO management, team leadership, and data-driven experimental design.
Microsoft 365, Google Workspace, Jira, Asana, LIMS, Benchling, R2DIO, Slack, Microsoft Teams, JMP, Spotfire, R, ChatGPT, Claude, Gemini
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