1mo
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Associate Manufacturing – Downstream - Nights (Multiple Positions)
Holly Springs, North Carolina, United States
$71k-$96k/yr OnsiteFull Time
0+ YOE12-hour night shift Associate performing downstream cGMP manufacturing tasks (chromatography, TFF), using EBR/MES/DeltaV, following SOPs, with HS/GED +2 yrs manufacturing OR Associate +6 months OR Bachelor acceptable.
Electronic Batch Records (EBR), MES, DeltaV, Electronic Quality Systems, Microsoft Office, Column Chromatography, Tangential Flow Filtration
4d
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Senior Manager: Manufacturing - Downstream Bulk Drug Substance
Holly Springs, North Carolina, United States
$136k-$184k/yr OnsiteFull Time
2+ MgmtLeadership of 24/7 downstream purification manufacturing, commissioning/qualification experience, workforce planning, training, GMP compliance, and technical problem solving; managerial experience required.
3w
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Specialist Manufacturing – Process Owner - Upstream / Downstream / Services
Holly Springs, North Carolina, United States
$108k-$146k/yr OnsiteFull Time
2+ YOETechnical expertise in upstream/downstream/manufacturing services, GMP experience, MES/EBR familiarity, process ownership, troubleshooting, SOP authoring; degree and biotech operations experience required (varies by degree).
Manufacturing Execution Systems (MES), Electronic Batch Record (EBR)
1mo
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Senior Manager Process Engineering - Bulk Drug Substance - Downstream
Holly Springs, North Carolina, United States
$149k-$201k/yr OnsiteFull Time
2+ MgmtRequires substantial engineering and leadership experience to manage process/equipment engineering for downstream biologics manufacturing, support commissioning/qualification, ensure cGMP compliance, and lead continuous improvement.
Chromatography, Viral Filtration, UFDF, CIP/SIP
1mo
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Associate Manufacturing - Bulk Drug Substance Downstream - Days
Holly Springs, North Carolina, United States
$71k-$96k/yr OnsiteFull Time
0+ YOEHigh School/GED +2 yrs manufacturing (or Associate's +6 months, or Bachelor's) to support 24/7 cGMP downstream operations, follow SOPs, perform chromatography/TFF tasks, EBR documentation, and work 12-hour shifts including weekends, holidays, and overtime.
Electronic Batch Records (EBRs), EBR/MES, Delta V, Microsoft Office, Electronic Quality Systems
2d
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Front Line Manufacturing Manager (Bulk Drug Substance - Downstream) - Night Shift
Holly Springs, North Carolina, United States
$106k-$144k/yr OnsiteFull Time
3+ YOEManagerial manufacturing role in downstream biologics production; requires manufacturing/operations experience, prior people leadership, strong cGMP and regulatory knowledge, and technical/process expertise.
Microsoft, EBR/MES, Delta V, Electronic quality systems
2d
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Digital Operations Associate, Downstream
Holly Springs, North Carolina, United States
OnsiteFull Time
0+ YOESupport and sustain digital manufacturing tools in a cGMP environment; basic understanding of cGMP and data integrity; attention to detail, communication, and ability to follow procedures.
Manufacturing Execution Systems (MES), PI/data historian, data historian, electronic logbooks, DCS/PLC, LIMS, ERP
2d
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Digital Operations Associate, Downstream
Holly Springs, North Carolina, United States
OnsiteFull Time
Supports deployment and sustainment of digital manufacturing tools in a cGMP environment; foundational cGMP knowledge, attention to detail, ability to follow procedures, and willingness to support 24/7 operations.
Manufacturing Execution Systems (MES), PI, DCS, PLC, LIMS, ERP, electronic logbooks, data historian
1mo
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Process Engineer - Solution Prep, Upstream, and Downstream
Holly Springs, North Carolina, United States
$88k-$119k/yr OnsiteFull Time
2+ YOEDegree in engineering (multiple education/experience alternatives) plus 2+ years engineering experience (min). Must support GMP biopharmaceutical commissioning, qualification, troubleshooting, and 24/7 operational coverage; up to 10% travel.
Data Analytics, Root Cause Analysis (RCA), Statistical Process Control (SPC), Six Sigma, Predictive Maintenance
1mo
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Senior Process Engineer - Solution Prep, Upstream, and Downstream
Holly Springs, North Carolina, United States
$115k-$156k/yr OnsiteFull Time
4+ YOEQualifications include advanced degree or equivalent experience (Doctorate OR Master’s +2 yrs OR Bachelor’s +4 yrs OR Associate +8 yrs OR HS +10 yrs). Preferred: chemical/mechanical engineering, 6+ yrs relevant with 5+ yrs in biopharma ops, GMP equipment experience, tech transfer, commissioning/qualification, regulated environment experience, and o...
weigh and dispense equipment, solution preparation vessels, cell culture reactors, centrifugation, chromatography, viral filtration skids, UFDF skids, autoclaves, clean in place (CIP) systems, clean steam, water for injection
3w
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Specialist Manufacturing New Product Introduction (NPI):Downstream Readiness
Holly Springs, North Carolina, United States
$108k-$146k/yr OnsiteFull Time
2+ YOEBiologics manufacturing background with cross-functional project management, GMP experience, technical writing, and 2+ years biotechnology operations experience (varies by degree).
1mo
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Front Line Manufacturing Manager (Bulk Drug Substance - Downstream) - Day Shift
Holly Springs, North Carolina, United States
$106k-$144k/yr OnsiteFull Time
Managerial manufacturing role in cGMP drug substance production; requires relevant degree-plus-experience pathway or extensive manufacturing experience and prior people management; strong leadership, technical, and regulatory knowledge.
Microsoft, EBR/MES, Delta V, Electronic quality systems
1d
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Sr. Global Market Manager, Molecular
Salt Lake City or Raleigh or Durham or St. Louis
$121k-$182k/yr HybridFull Time
7+ YOE3+ MgmtBachelor's degree,7+ years in marketing/commercial roles with 3+ years downstream marketing,experience in diagnostics preferred,advanced MS Office skills,global cross-functional collaboration and travel (~30%).
Microsoft Outlook, Microsoft Teams, Microsoft Word, Microsoft Excel
1w
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Process Validation Engineer
Raleigh or Durham
$70-$80/hr OnsiteContract
5+ YOEBS in engineering, 5+ years pharmaceutical/biotech GMP process or manufacturing engineering experience, hands-on upstream/downstream/clean utilities experience, cGMP knowledge, able to work onsite in Raleigh-Durham.
1mo
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Senior Manufacturing Operator
Sanford or Princeton or Mississauga or California or North Carolina
$33-$45/hr OnsiteFull Time
4+ YOEHands-on GMP biopharmaceutical manufacturing experience executing upstream/downstream processes, equipment commissioning/validation, cGMP and data integrity adherence, PCS/MES/ERP/LIMS proficiency, SOP development, troubleshooting, and training.
ERP, LIMS, MES, PCS, QMS, BMS, DeltaV, Unicorn, Ignition, Microsoft Office
1mo
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Senior Manufacturing Systems Engineer – DeltaV Batch
Holly Springs, North Carolina, United States
$137k-$185k/yr OnsiteFull Time
2+ YOELead automation engineering projects for upstream/downstream/solution prep using Emerson DeltaV DCS; support commissioning/qualification, 24/7 operational support, troubleshooting, SOP/cGMP documentation, and mentor engineering staff.
Emerson DeltaV, Distributed Control System (DCS), OPC, Foundation Fieldbus, Profibus
3w
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Manager, Process Engineering
Holly Springs, North Carolina, United States
OnsiteFull Time
4+ YOE4+ MgmtBachelor's in engineering + 6+ years engineering experience (4+ years in life sciences) OR Master's + 4+ years; 4+ years managing people; experience with cell culture and downstream unit operations; greenfield startup and project-driven experience.