33 hpc engineer jobs at 19 companies in Boston, MA

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HPC Operations Engineer
Santa Clara or Durham or Austin or Westford
$124k-$242k/yr HybridFull Time
NVIDIA
NVIDIANASDAQ: NVDA: Designs graphics processing units and artificial intelligence hardware.
2+ YOEBachelor's or equivalent experience,2+ years supporting Linux production (RHEL/CentOS/Ubuntu),experience with schedulers (LSF/Slurm),networking (NFS,automounter,LDAP),strong troubleshooting,written communication,automation scripting preferred.
RHEL, CentOS, Ubuntu, Bash, Python, LSF, Slurm, NFS, automounter, LDAP, EDA
2w
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AI HPC Infrastructure Engineer
Boston, Massachusetts, United States
$150k-$170k/yr HybridFull Time
Analysis Group
Analysis Group: Provides economic, financial, and strategy consulting to businesses and governments.
5+ YOEBachelor's degree and 5+ years Linux/HPC systems administration experience; expertise with NVIDIA GPU stack, SLURM, GPFS, Kubernetes, Python/R, LLM tuning, Posit Workbench; must be authorized to work in the US.
Posit Workbench (RStudio Server Pro), MPI, OpenMP, PyTorch Distributed, Horovod, DeepSpeed, SLURM, Kubernetes, CUDA, cuDNN, NCCL, MLflow, Kubeflow, Docker, Singularity/Apptainer, GPFS (IBM Spectrum Scale), Bright Cluster Manager, Ansible, RDP, SSH, PyTorch, TensorFlow, Weights & Biases, NVIDIA GPU Operator, LiteLLM, Kong AI Gateway, Portkey
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HPC Operations Engineer
Santa Clara or Westford or Austin or Durham
$124k-$242k/yr HybridFull Time
NVIDIA
NVIDIANASDAQ: NVDA: Designs GPU-accelerated computing and artificial intelligence hardware.
2+ YOEBachelor's or equivalent experience,2+ years supporting Linux production,experience with RHEL/CentOS or Ubuntu,methodical troubleshooting,user-facing support skills,and written documentation ability.
Linux, RHEL, CentOS, Ubuntu, Bash, Python, LSF, Slurm, NFS, automounter, LDAP, EDA
3w
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HPE Labs - Senior Software Engineer – Integrated HPC & Quantum Solutions
Milpitas or Albuquerque or Fort Collins or Santa Barbara or Chicago or Boston or Knoxville
$120k-$275k/yr HybridFull Time
Hewlett Packard Enterprise
Hewlett Packard EnterpriseNYSE: HPE: Providing global edge-to-cloud infrastructure and IT solutions for businesses.
6+ YOEMaster's or equivalent experience,6+ years programming,advanced skills in C/C++/Rust and Python,experience with quantum computing tools and HPC,strong math and software engineering background.
Qiskit, CUDA-Q, TensorFlow Quantum, Pennylane, C, C++, Rust, Python, Linux command line tools, TensorFlow, PyTorch, MLIR
3w
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HPE Labs - Senior Software Engineer – Integrated HPC & Quantum Solutions
Milpitas or Albuquerque or Fort Collins or Santa Barbara or Chicago or Boston or Knoxville
$120k-$275k/yr HybridFull Time
Hewlett Packard Enterprise
Hewlett Packard EnterpriseNYSE: HPE: Provides edge-to-cloud IT infrastructure and platform services.
6+ YOEMaster's degree or equivalent, 6+ years programming, advanced skills in C/C++/Rust and Python, quantum computing and HPC experience, familiarity with Qiskit/CUDA-Q/TensorFlow Quantum/Pennylane, Linux, GPU/HPC architecture, and ML/compilers.
C, C++, Rust, Python, Qiskit, CUDA-Q, TensorFlow Quantum, Pennylane, Linux, TensorFlow, PyTorch, MLIR
3w
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HPE Labs - Senior Software Engineer – Integrated HPC & Quantum Solutions
Milpitas or Albuquerque or Fort Collins or Santa Barbara or Chicago or Boston or Knoxville
$120k-$275k/yr HybridFull Time
Hewlett Packard Enterprise
Hewlett Packard EnterpriseNYSE: HPE: Provides global edge-to-cloud technology solutions and IT infrastructure services.
6+ YOEMaster's or equivalent,6+ years programming, advanced skills in C/C++/Rust and Python, experience with quantum computing tools and HPC, strong math and communication skills.
C, C++, Rust, Python, Qiskit, CUDA-Q, TensorFlow Quantum, Pennylane, TensorFlow, PyTorch, MLIR, Linux
2d
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Staff Software Engineer, HPC
Foster City or Boston or Seattle
$230k-$295k/yr HybridFull Time
Zoox
ZooxNASDAQ: AMZN: Developing autonomous robotaxis for urban ride-hailing services.
Experience operating large-scale distributed systems, Ray.io, Kubernetes, AWS or similar cloud infrastructure, reliable scalable systems, cross-functional planning, and Python proficiency.
Ray.io, SLURM, Kubernetes, AWS, Python
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Distinguished Engineer, Full Stack (Remote Eligible)
Cambridge or Richmond or New York City or McLean or United States
$245k-$335k/yr RemoteFull Time
Capital One
Capital OneNYSE: COF: Provides credit card, banking, and auto loan services.
7+ YOEBachelor's degree and 7+ years in software engineering, solution or enterprise architecture, distributed HPC/ML systems, cloud computing, and data engineering; advanced coding and AI-native engineering experience preferred.
Python, Java, Go, Scala, JavaScript, TypeScript, AWS, Microsoft Azure, Google Cloud
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Staff Engineer High Performance Computing
New York City or Cambridge
$139k-$232k/yr HybridFull Time
Pfizer
PfizerNYSE: PFE: Develops and manufactures vaccines and medicines for global healthcare
6+ YOEBachelor's degree and 6+ years in cloud infrastructure engineering; expert AWS or GCP experience, HPC frameworks, CI/CD, observability, distributed systems, networking, identity, and security.
AWS, GCP, Terraform, Microsoft CloudFormation, CloudWatch, Prometheus, Grafana, EKS, GKE, Kubernetes, NVIDIA GPU, AWS ParallelCluster, Parallel Computing Services, Google Cloud Cluster Toolkit, Linux, CI/CD, Infrastructure as Code (IaC)
2mo
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Associate Staff - Aerospace Engineer (Lexington, MA, US)
Lexington, Massachusetts, United States
$116k-$182k/yr OnsiteFull Time
MIT Lincoln Laboratory
MIT Lincoln Laboratory: Building advanced technology prototypes for national security.
3+ YOEMS in Aerospace or Mechanical Engineering; or BS with 3+ years of relevant experience; CFD and high-speed flow coursework; programming for engineering algorithms; strong communication and interdisciplinary teamwork.
Linux, US3D, SPARC, FUN3D, Kestrel, Cart3D, Pointwise, Link3D, HPC, surrogate modeling, machine learning, Git
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Biological Structures Data Engineer I/II
Boston, Massachusetts, United States
$130k-$190k/yr HybridFull Time
Iambic Therapeutics
Iambic Therapeutics: Develops novel medicines using an AI-driven discovery platform.
3+ YOEPhD or equivalent experience in bioinformatics/computational biology/cheminformatics; hands-on familiarity with structural biology data (.cif/PDB); strong software engineering and Python skills; experience with data pipelines and cloud/HPC preferred.
Python, AWS, Kubernetes, HPC, .cif, PDB
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Research Engineer, Accelerated Quantum Chemistry
Cambridge or London
OnsiteFull Time
Dayhoff Labs
Dayhoff Labs: AI-driven discovery for synthetic biology and chemical processes.
3+ YOEPhD in computational chemistry/materials science or Master's with 3+ years experience; hands-on QM/MD package and pipeline experience; Python, NumPy, SciPy, PyTorch or TensorFlow; HPC and containerization experience.
VASP, Gaussian, ORCA, GROMACS, LAMMPS, CP2K, Python, NumPy, SciPy, PyTorch, TensorFlow, Docker, HPC
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Distinguished Engineer, Back End (Remote Eligibe)
Cambridge or United States or McLean or Richmond or New York City
$245k-$335k/yr RemoteFull Time
Capital One
Capital OneNYSE: COF: Financial services offering credit cards, banking, and loans.
7+ YOEBachelor's degree and 7+ years in software engineering/architecture, experience with distributed HPC/ML systems, cloud platforms, and mentoring; strong coding and AI/ML practice.
AI and ML frameworks, AWS, Microsoft Azure, Google Cloud, Python, Java, Go, Scala, JavaScript, TypeScript
3w
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Sr. Tech Sales Engineer Rep, New England
Morrisville or Boston or Springfield or Worcester or Manchester or Cambridge or Hartford
$115k-$130k/yr OnsiteFull Time
Lenovo
LenovoHKSE: 992: Manufactures personal computers, mobile devices, and server infrastructure.
2+ YOEDegree in computer science/engineering or equivalent experience, 2+ years technical sales (or 5+ as systems admin), knowledge of virtualization, storage, Linux, HPC, and consultative selling skills.
VMware, Linux, Hyper-V, Windows Server, NetApp Storage, Azure, Nutanix, Veeam, Commvault, Slurm, PBS, LSF, Lustre, BeeGFS, IBM Storage Scale, MPI
1d
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Principal Software Engineer - Compiler Development
Burlington, Massachusetts, United States
$118k-$218k/yr OnsiteFull Time
Cadence Design Systems
Cadence Design SystemsNASDAQ: CDNS: Develops computational software and hardware for electronic system design.
5+ YOERequires BS and 10+ years, MS and 7+ years, or PhD and 5+ years; 5+ years in compiler development, EDA, or HPC; expert C++, SystemVerilog or Verilog, and compiler theory.
C++, SystemVerilog, Verilog, LLVM, Python, UVM
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Senior Backend Software Engineer
Watertown, Massachusetts, United States
OnsiteFull Time
Flexcompute
Flexcompute: Develops GPU-native multiphysics simulation software for hardware engineers.
Bachelor's in CS/CE required; senior-level backend experience with Java, Python, or C++; strong AWS/cloud, Docker/Kubernetes, distributed systems, Linux, infrastructure automation (Terraform/Ansible), and web API design.
Java, Python, C++, AWS, Docker, Kubernetes, Linux, Terraform, Ansible, Slurm, Flow360, Tidy3D, CI/CD, HPC
2d
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Biostatistician Principal
Boston, Massachusetts, United States
$57-$82/hr HybridPart Time
Mass General Brigham: Provides integrated medical care, research, and clinical training services.
7+ YOEDoctorate and 7+ years of postdoctoral research in myeloid malignancy epigenetics; software engineering, pathology, NGS pipeline authorship, methylation analysis, R, Python, Unix/Linux, HPC, and cloud-scale computing expertise required.
R, Python, Unix/Linux, HPC, WGBS, RRBS, ChIP-seq, CUT&RUN, ATAC-seq, RNA-seq, RIP-seq, single-cell RNA-seq, CITE-seq
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Senior Scientist, Biomarker Discovery Automation & Engineering, Multiomics
Cambridge, Massachusetts, United States
$131k-$207k/yr OnsiteFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Produces prescription medicines, vaccines, and animal health products.
0+ YOEPh.D. with 0–3+ years or master's with 3–5+ years; requires automation and omics workflow experience, instrumentation troubleshooting, SOP documentation, Linux/Unix, HPC, scripting, and strong communication skills.
CosMx WTx, Xenium, COMET mIF, Digital Pathology, MSI, REAP-seq, CITE-seq, CROP-seq, Perturb-seq, Multiome ATAC-seq, Parse-seq, 10x Flex, Olink HT, CRISPR, Linux, Unix, High-Performance Computing (HPC), Basic HSL, R, R Shiny, Python, MATLAB, Machine Learning (ML)
3d
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Senior Scientist, Biomarker Discovery Automation & Engineering, Multiomics
Cambridge, Massachusetts, United States
$131k-$207k/yr OnsiteFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Develops and manufactures prescription medicines, vaccines, and animal health products.
3+ YOEPh.D. with 0–3+ years post-graduate experience or master's degree with 3–5+ years; expertise in automated omics workflows, instrumentation, troubleshooting, technology transfer, SOPs, Linux/Unix, HPC, and scientific communication.
Linux, Unix, High Performance Computing (HPC), Basic HSL, R, R Shiny, Python, MATLAB, CosMx WTx, Xenium, COMET mIF, Digital Pathology, MSI, REAP-seq, CITE-seq, CROP-seq, Perturb-seq, Multiome ATAC-seq, Parse-seq, 10x Flex, Olink HT
1mo
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Senior Product Manager (AI Infrastructure & GPU)
Cambridge or United States
$139k-$251k/yr HybridFull Time
Akamai
AkamaiNASDAQ: AKAM: Provides content delivery, cybersecurity, and cloud computing services globally.
12+ YOE12 years experience and Bachelor's in CS/Engineering (or equivalent); deep expertise in GPU architectures/CUDA, cloud networking, product strategy, financial modeling, and AI/HPC workload patterns.
CUDA