28 hpc jobs at 18 companies in San Diego, CA
3mo
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HPC Systems Engineer (Linux / Infrastructure)
San Diego, California, United States
$116k-$209k/yr OnsiteFull Time
15+ YOEBachelor's degree or equivalent experience, 15+ years systems administration experience, deep Linux stack knowledge (NFS, ZFS, BTRFS, mdadm, LVM), scripting with Python/Ansible/Bash, troubleshooting distributed systems; SLURM and parallel file system experience desirable.
Lustre, BeeGFS, WEKA, Ceph, SLURM, Ansible, Python, Bash, Docker, Podman, Apptainer, NFS, ZFS, BTRFS, mdadm, LVM
3d
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AI & HPC Infrastructure Engineer
Albany or Arlington or Atlanta or Austin or Beaverton or Bentonville or Boston or Carmel or Charlotte or Chicago or Cincinnati or Cleveland or Columbus or Culver City or Denver or Des Moines or Detroit or Hartford or Houston or Irvine or Irving or Kirkland or Miami or Milwaukee or Minneapolis or Morristown or Mountain View or Nashville or New York City or Oklahoma City or Overland Park or Philadelphia or Pittsburgh or Raleigh or Redmond or Sacramento or San Diego or San Francisco or Scottsdale or Seattle or St. Louis or St. Petersburg or Walnut Creek or United States
$80k-$266k/yr HybridFull Time
5+ YOERequires 5+ years designing AI infrastructure, accelerated computing, clusters, orchestration, and automation; bachelor's degree or equivalent experience. Strong Kubernetes, Python, Terraform, and cloud expertise required.
Slurm, Run:ai, Kubernetes, NVIDIA Base Command Manager (BCM), NVIDIA NGC, NCCL, NVLink, CUDA, TensorRT-LLM, vLLM, SGLang, Triton Inference Server, NVIDIA Dynamo, llm-d, MLPerf, NCCL tests, fio, iperf, InfiniBand, Ethernet, SONiC, NVMe, NVMe-oF, VAST, Weka, DDN, AWS, Azure, GCP, VMware, Nutanix, Python, Terraform, Ansible, REST, OpenAPI, JSON, YAML, TensorFlow, PyTorch, JAX, Jupyter notebooks, Google Colab, MCP
1mo
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Senior Engineer – AI & HPC Observability
San Diego or Austin
$155k-$206k/yr OnsiteFull Time
5+ YOEBachelors in CS/CE or equivalent; 5+ years observability and distributed systems experience; 1+ year HPE OpsRamp; strong Bash and Python; experience with OpenTelemetry, Prometheus, Grafana, Datadog, ELK, ThousandEyes; cloud skills (AWS/GCP/OpenStack/Proxmox/k8s).
HPE OpsRamp, Open Telemetry, Prometheus, Grafana, Nagios, Datadog, ELK, Thousand Eyes, Bash, Python, AWS, GCP, OpenStack, Proxmox, k8s, Netbox, MaaS, Redfish
4d
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Assistant, HPC Install
San Diego, California, United States
$20-$22/hr FieldFull Time
2+ YOEHigh school diploma or GED, valid driver's license, and at least 2 years of general construction experience. Requires technical knowledge, problem-solving skills, physical stamina, and ability to work at heights and in confined spaces.
hand tools, power tools
1w
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Software Engineer
San Diego, California, United States
$108k-$128k/yr HybridFull Time
2+ YOERequires 2–5 years of software engineering experience, strong Python, Linux and HPC familiarity, CI/CD and package tooling experience, JavaScript knowledge, and debugging skills.
Python, Jenkins, Bitbucket, Poetry, Linux, HPC, Airflow, JavaScript, TypeScript, Numpy, Scipy, RAPIDS, POLARS, PostGRES, celery, Flask, Django, Docker
1mo
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Strategic Advisor, Nonprofit Research and Advanced AI, AWS Global Nonprofit Business
Seattle or Arlington or New York or San Diego
OnsiteFull Time
10+ YOEMaster's degree or PhD/equivalent research experience; 10+ years in nonprofit or academic research with demonstrated thought leadership; deep expertise in research computing, AI/ML, HPC, and familiarity with NIH/NSF funding ecosystems.
AWS, HPC, LinkedIn
3w
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Computational & Data Science Research Spec. 2 or 3 - 139471
San Diego, California, United States
$88k-$182k/yr OnsiteFull Time
2+ YOEBachelor's in CS/Data Science required; 2+ years relevant experience (2-5 yrs typical); strong AI, systems, algorithms, and software engineering skills; Python, cloud, React, HPC experience preferred.
Python, React, cloud computing, HPC, LLM
1mo
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Innovation Postdoctoral Fellow, Data Science & AI Vision Foundation Models for Cellular Imaging in AI Drug Discovery
San Diego, California, United States
$87k/yr OnsiteFull Time
PhD (conferred in 2026) in a relevant scientific discipline, proficiency in Python and modern deep learning frameworks, hands-on GPU/HPC/cloud experience, knowledge of vision foundation models and self-supervised learning, strong communication and publication record.
Python, PyTorch, TensorFlow, JAX, GPUs, HPC, cloud, MLflow
1mo
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DIRECTOR, HIGH PERFORMANCE COMPUTING
San Diego, California, United States
$136k-$195k/yr HybridFull Time
10+ YOEBachelor's in a technical field,10+ years in HPC/research computing,experience with shared services and recharge models,cloud/on-prem HPC knowledge,and staff supervision; strong communication and strategic planning skills.
2mo
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AI in Business, Postdoctoral Research Fellow
San Diego, California, United States
$65k-$68k/yr OnsiteFull Time, Temporary
Ph.D. (completed or expected) in a related field; experience with deep learning (PyTorch), multi-GPU/HPC environments, publications, grant writing, and mentoring students; expertise in multimodal AI preferred.
PyTorch, NVIDIA DGX B200, Weights and Biases, MLflow, LoRA, PEFT, QLoRA
1mo
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Innovation Postdoctoral Fellow, Data Science & AI
San Diego, California, United States
$58k-$107k/yr OnsiteFull Time
PhD required prior to start; proficiency in Python and modern deep learning frameworks; experience training deep learning models on GPUs/HPC or cloud; knowledge of vision foundation models and evaluation protocols.
Python, PyTorch, TensorFlow, JAX, MLflow
2w
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Software Engineer
Vista, California, United States
OnsiteFull Time
Degree in computer science/engineering or physics; experience programming in C++, CMake on Windows, Qt 5; familiarity with EMR? (not present) — exclude; desirable: HPC, C++17, VTK, PostgreSQL, Doxygen, Python 3.6.
C++, CMake, Qt 5, C++17, Visualization Toolkit (VTK), PostgreSQL, Doxygen, Python 3.6
1mo
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Scientific Director, Computational Chemistry
San Diego, California, United States
$218k-$298k/yr OnsiteFull Time
8+ YOEAdvanced degree plus 8+–12+ years computational chemistry drug discovery experience, leadership experience, expertise in molecular modeling, SBDD, cheminformatics, AI/ML, cloud/HPC workflows, and experience integrating computational methods into multidisciplinary teams.
Knime, Schrödinger, OpenEye, MOE
1w
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Snowflake Advanced AI Solution Lead
San Francisco or Milwaukee or Dallas or Columbus or Kirkland or Cincinnati or New York City or Cleveland or Oklahoma City or Austin or Albany or Chicago or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Mountain View or Scottsdale or Morristown or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
$80k-$294k/yr HybridFull Time
5+ YOERequires 5+ years in machine learning engineering or science, 5+ years in computer science foundations, 3+ years in distributed systems, 2+ years with Snowflake Cortex AI and cloud AI/ML deployment, plus a bachelor's degree or equivalent experience.
Snowflake Cortex AI, Cortex Agents, Cortex Analyst, Cortex Search, Deep Learning, Generative AI, Large Language Models, DevOps, MLOps, LLMOps, HPC, Python, TensorFlow, PyTorch, LLM, C++, Java, R, SQL
1d
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IT DevOps Applications Engineer - Hardware Engineering
San Diego, California, United States
$102k-$154k/yr OnsiteFull Time
5+ YOEBachelor’s degree or equivalent practical experience and 5 years supporting enterprise Windows desktop, virtual desktop, or Citrix environments; experience with automated testing and CI/CD pipelines required.
Windows, Windows Virtual Desktop Infrastructure (VDI), Citrix, Linux, High Performance Computing (HPC), PowerShell, CI/CD, Ansys, Star-CCM+, HyperWorks, MATLAB, Agile, Scrum, SAFe, Computational Fluid Dynamics (CFD), Finite Element Analysis (FEA)
2mo
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Advisor - Data Architect, Data Foundry
San Diego or San Francisco or Boston or Louisville or Indianapolis
$152k-$244k/yr OnsiteFull Time
2+ YOEM.S. or PhD in a STEM field with relevant data architecture/engineering or scientific informatics experience (MS+6 yrs or PhD+2 yrs). Expertise in data modeling, lakehouse and platform architecture, knowledge graphs, semantic web standards, cloud and streaming data patterns.
Databricks, Snowflake, Spark, dbt, Kafka, Kinesis, Flink, Neo4j, Amazon Neptune, TigerGraph, TileDB, MongoDB, Pinecone, Weaviate, pgvector, Delta Lake, Unity Catalog, RDF, OWL, SPARQL, Protégé, Benchling, C, C++, Rust, SQL, LIMS, ELN, HPC
1mo
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Scientist, Computational Chemist & MLOps Engineer
Madison or Pasadena or San Diego or Verona
$100k-$125k/yr OnsiteFull Time
Bachelor's or Master's in a related field; strong Python, Linux, and Git skills; foundational statistics and ML knowledge; experience with biological/omics datasets, reproducible workflows, and scientific software; PhD preferred for senior levels.
Python, Linux, Git, HPC
2mo
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Systems Engineer - Microsoft Windows
La Jolla, California, United States
$101k-$161k/yr OnsiteFull Time
6+ YOE6+ years IT experience with 4+ years systems administration (or 8+ years with HS); advanced Linux and Windows server administration; VMware, scripting (Shell/Perl/PHP/PowerShell), patching, automation, and security hardening; ability to obtain Top Secret/SCI and DOD 8570 IAT II.
Active Directory, GPO, HPC, Nessus, Perl, PHP, PowerShell, RHEL, SQL, Shell, STIGs, VMware vSphere, vCenter, Windows Server 2022, Windows 11, Microsoft Office, Microsoft SharePoint, Microsoft WSUS, Microsoft SCCM, DNS, DHCP, VLANs, Omnissa Horizon
2mo
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Machine Learning Scientist – Clinical Prediction
Boston or San Diego or United States
$148k-$186k/yr HybridFull Time
3+ YOEMS in chemistry/bio/chemical engineering or PhD/equivalent; 3+ years relevant experience; strong Python and deep-learning fine-tuning skills; clinical dataset experience; data science and engineering best practices; familiarity with Docker, CUDA, Kubernetes, and Weights & Biases.
Python, Docker, CUDA, Kubernetes, Weights & Biases, HPC
1w
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Senior Software Engineer - Defense Simulation
Fort Walton Beach or Sunnyvale or Washington or San Diego or Ann Arbor or London or Stuttgart or Munich or Stockholm or Bengaluru or Seoul or Tokyo
$140k-$180k/yr OnsiteFull Time
3+ YOEMaster’s degree or equivalent experience, 3+ years modern C++ development, simulation interoperability and communication protocols, Linux, Docker, Git, and eligibility for a U.S. Secret clearance.
C++, Python, DIS, HLA, DSEEP, DDS, ZeroMQ, Kafka, Redis, protobuf, AFSIM, NGTS, Docker, RHEL, Ubuntu, git, Visual Studio Code, GitLab, SonarQube, Artifactory, Azure Container Registry, OMS, UCI, HPC
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