11 lead data scientist jobs at 8 companies in Denver, CO

PromotedHiringCafe
Founding Machine Learning / AI Search Engineer
Cupertino, CA, US
$160k-$310k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Build the ML and AI search behind HiringCafe — ranking, recommenders, retrieval, and LLM agents that surface jobs people would never find on their own.
Python, PyTorch, Elasticsearch, LLMs
1mo
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Lead Data Scientist
Irving or Cape Girardeau or Chicago or Centennial
$118k-$206k/yr OnsiteFull Time
Vizient
Vizient: Healthcare performance improvement and group purchasing organization.
7+ YOE7+ years experience in data science with expertise in machine learning, generative and agentic AI, LLMs, RAG, statistical modeling, production deployment, cloud platforms, and mentoring technical teams.
Python, R, SQL, SAS, Databricks, large language models (LLMs), retrieval-augmented generation (RAG), vector databases, knowledge graphs
4w
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Data Scientist Lead
Denver, Colorado, United States
$104k-$166k/yr HybridFull Time
Denver Health
Denver Health: Provides comprehensive hospital and emergency medical services in Denver.
7+ YOEBachelor's in a related field, 7-9 years working with Epic databases, expert SQL and reporting skills, Epic/Caboodle Cogito proficiency, MS Office, SSMS, Tableau, Git, project leadership and mentorship experience.
CABOODLE-EPIC Cogito Data Warehouse, Epic, SSMS, SQL, Tableau, Git, Microsoft Word, Microsoft Excel, Microsoft PowerPoint
3w
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Lead Data Scientist, AdTech
Denver or Las Vegas or Phoenix or Salt Lake City or Tucson
$175k-$200k/yr RemoteFull Time
Launch Potato
Launch Potato: Digital media operating a portfolio of consumer brands.
5+ YOE5+ years applied data science in digital/performance marketing or leadgen; hands-on AWS ML deployment; experience building adtech algorithms, recommender and ranking systems, LTV and monetization models; expert Python and SQL; strong modeling fundamentals and stakeholder communication.
AWS, Python, SQL, Looker, Google, Meta, LLMs
2d
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Lead, Data Scientist - Decision Sciences Identity Team
Chicago or Wakefield or Irving or Westminster or Boston
$87k-$174k/yr HybridFull Time
Publicis Groupe
Publicis GroupeEuronext Paris: PUB: Global communications, advertising, and digital transformation holding.
2+ YOEPhD in quantitative field, 2+ years relevant programming experience, strong ML/statistics background, Python proficiency, ability to deliver research projects and translate findings for non-technical audiences.
Python, Spark, Hadoop, Databricks, AWS, S3, SQL, Scala
2d
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Lead, Data Scientist - Decision Sciences Identity Team
Chicago or Wakefield or Irving or Westminster or Boston
OnsiteFull Time
Publicis Groupe
Publicis GroupeEuronext Paris: PUB: Global advertising and digital transformation agency holding.
2+ YOEPhD in a quantitative field, ML research experience, strong Python and programming skills, 2+ years relevant programming experience, ability to deliver research to production, strong communication.
Python, SQL, Scala, Spark, Hadoop, Databricks, AWS, S3, LLMs
1mo
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Senior Data Scientist Engineer
Aurora, Colorado, United States
$194k-$262k/yr OnsiteFull Time
Four Sea Group
Four Sea Group: Technical mission support and software engineering for aerospace.
10+ YOEBachelor's in a quantitative field, 10+ years designing, training, and deploying production ML models, active TS/SCI with Full Scope Polygraph, proficiency with Python and ML tooling, experience leading complex AI/ML efforts.
Python, TensorFlow, PyTorch, Scikit-learn, XGBoost, Spark, Ray, Dask, MLflow, DVC, Docker, Git, Jupyter Notebooks, Confluence, SHAP, LIME
3w
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Lead Applied Scientist, Marketing
Denver or Las Vegas or Phoenix or Salt Lake City or Tucson
$175k-$200k/yr RemoteFull Time
Launch Potato
Launch Potato: Digital media operating a portfolio of consumer brands.
5+ YOE5+ years applied data science experience in performance/leadgen marketing; hands-on ML in AWS; expertise in bandits, recommender systems, LTV modeling; strong Python and SQL skills.
AWS, Python, SQL, Looker, Google, Meta, LLMs
1mo
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Mid-Level Data Scientist Engineer (TS/SCI with CI Polygraph)
Aurora, Colorado, United States
$135k-$155k/yr OnsiteFull Time
DeNOVO Solutions
DeNOVO Solutions: Provides defense and intelligence technology, software engineering, and cybersecurity services.
5+ YOETS/SCI with CI Polygraph required; 5+ years designing, training, and deploying ML models in DoD/IC; Bachelor's in quantitative field (or equivalent); experience leading technical teams and production ML systems.
TensorFlow, PyTorch, Scikit-learn, XGBoost, Spark, Ray, Dask, MLflow, DVC, Docker, SHAP, LIME, Jupyter Notebooks, Git, Confluence
2mo
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Senior Data Scientist Engineer (TS/SCI with CI Polygraph)
Aurora, Colorado, United States
OnsiteFull Time
DeNOVO Solutions
DeNOVO Solutions: Provides defense and intelligence technology, software engineering, and cybersecurity services.
10+ YOE10-15 years designing, training, and deploying ML models for DoD/IC; lead technical teams or enterprise AI initiatives.
TensorFlow, PyTorch, Scikit-learn, XGBoost, Spark, Ray, Dask, MLflow, Docker, SHAP, LIME, Jupyter Notebooks, Git, Confluence
2d
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Data Science Team Leader
Denver, Colorado, United States
$155k-$165k/yr HybridFull Time
bet365
bet365: Provides global online sports betting and digital casino games.
Proven experience leading and mentoring data scientists while remaining hands-on in Python; strong ML production experience, SQL and Google BigQuery proficiency, GCP and Vertex AI experience, Docker/Kubernetes, Kafka; MSc/PhD or equivalent.
Python, Scikit-learn, Pandas, NumPy, XGBoost, SQL, Google BigQuery, Google Cloud Platform (GCP), Vertex AI, Docker, Kubernetes, Kafka
2d
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Senior Research Scientist
Aurora, Colorado, United States
$95k-$105k/yr OnsiteFull Time
University of Colorado
University of Colorado: Public research university providing higher education and healthcare services.
PhD in epidemiology or related field, demonstrated expertise in epidemiology, clinical trials, and research synthesis; ability to lead projects, teach, and collaborate; proficiency in data science and NLP methods.