18 ml systems engineer jobs at 13 companies in Missouri

6d
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Staff Software Engineer (302023)
Burlington or St. Louis
$111k-$166k/yr HybridFull Time
Merck
MerckXETRA: MRK: A science and technology providing healthcare, life science, and electronics solutions.
3+ YOEBachelor's degree in a quantitative field, 3+ years ML/data experience, strong Python and ML framework skills, cloud and distributed systems experience, production software engineering and data lifecycle expertise.
Python, REST API, Pandas, NumPy, AWS Services, GCP, Kubernetes, Bedrock, Kafka, LangGraph, LangChain, AirFlow, MLFlow, TensorFlow, PyTorch, Scikit-learn, Qdrant, Docker, Git, CI/CD
2mo
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Senior Security AI Engineer
Kansas City, Missouri, United States
OnsiteFull Time
Imperial PFS
Imperial PFS: Provides premium financing solutions for the commercial insurance industry.
7+ YOE7+ years in cybersecurity engineering with cloud security, AI/ML system protection, SIEM/EDR/XDR experience, threat modeling, risk management, and secure CI/CD practices.
AWS, Azure, GCP, SIEM, EDR/XDR, CAASM, EASM, Terraform, CloudFormation, Kubernetes
3w
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Staff AI Platform Engineer
San Francisco or Alabama or Arkansas or California or Colorado or Florida or Georgia or Illinois or Kentucky or Massachusetts or Michigan or Montana or Missouri or Nevada or New Jersey or New York or North Carolina or Oregon or Pennsylvania or Texas or Washington or Utah or Virginia or Wisconsin or United States
$169k-$273k/yr HybridFull Time
Afresh
Afresh: AI-powered inventory management for grocery store fresh food departments.
5+ YOE5+ years building production software/data/ML systems; strong Python, systems and API design; hands-on LLM systems (retrieval/RAG, agents, evaluation); Databricks/MLflow and modern data-platform experience.
Python, PySpark, dbt, Databricks, Delta Lake, Unity Catalog, MLflow, Astronomer, Airflow, Claude, pgvector, Pinecone, Weaviate, MCP, LangGraph, GitHub, Shortcut, Notion
3w
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Senior AI Platform Engineer
San Francisco or Alabama or Arkansas or California or Colorado or Florida or Georgia or Illinois or Kentucky or Massachusetts or Michigan or Montana or Missouri or Nevada or New Jersey or New York or North Carolina or Oregon or Pennsylvania or Texas or Washington or Utah or Virginia or Wisconsin
$156k-$231k/yr HybridFull Time
Afresh
Afresh: AI-powered inventory management for grocery store fresh food departments.
3+ YOE3+ years building production software or ML/data systems; strong Python and systems/API design; experience with LLM retrieval/RAG, agents, evaluation, Databricks/MLflow and modern data stacks.
Python, PySpark, dbt, Databricks, Delta Lake, Unity Catalog, MLflow, Astronomer, Airflow, Claude, GitHub, Shortcut, Notion, pgvector, Pinecone, Weaviate, LangGraph, MCP
1w
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Staff Software Engineer
St. Louis or Burlington
$111k-$166k/yr HybridFull Time
Merck
MerckXETRA: MRK: A science and technology providing healthcare, life science, and electronics solutions.
3+ YOEBachelor's in CS/Engineering/Data Science, 3+ years in ML/data/search systems, strong Python, backend and data engineering experience, SQL, cloud (GCP/AWS), and production ML/LLM system design.
Python, REST API, Pandas, NumPy, MLFlow, TensorFlow, PyTorch, Scikit-learn, AWS Services, GCP, Kubernetes, Bedrock, Kafka, LangGraph, LangChain, AirFlow, Qdrant, Docker, Git, CI/CD, SQL
1mo
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Principal Machine Learning Engineer
Denver or Arizona or Arkansas or California or Florida or Georgia or Illinois or Indiana or Iowa or Kansas or Maryland or Massachusetts or Michigan or Minnesota or Missouri or Montana or Nevada or New Jersey or New York or North Carolina or Ohio or Oklahoma or Pennsylvania or Tennessee or Texas or Utah or Virginia or Washington or Wisconsin
$228k-$253k/yr HybridFull Time
Ibotta
IbottaNYSE: IBTA: Provides a cash-back rewards and performance marketing platform.
10+ YOE10+ years building and deploying large-scale ML systems; expertise with cloud (AWS), big-data tools, ML frameworks, and leading ML strategy and mentoring engineers.
Python, Apache Spark, Databricks, AWS, Amazon SageMaker, scikit-learn, TensorFlow, Spark ML, Apache Kafka
4w
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Performance Engineer Intern, Systems Software- Fall 2026
St. Louis, Missouri, United States
$20-$71/hr OnsiteFull Time, Internship
NVIDIA
NVIDIANASDAQ: NVDA: Designs GPU-accelerated computing and artificial intelligence hardware.
Enrolled in a Bachelor's in CS/CE/SE or related; experience with Python and Linux; familiarity with ML lifecycle; teamwork and CS fundamentals; interest in performance benchmarking and containers.
Python, Linux, PyTorch, CUDA, cuOPT, CUTLASS, cuDNN, Kubernetes, Slurm
2w
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Staff Software Engineer (301771)
St. Louis or Burlington
$111k-$166k/yr HybridFull Time
Merck
MerckXETRA: MRK: A science and technology providing healthcare, life science, and electronics solutions.
3+ YOEBachelor's in CS/engineering/data science, minimum 3 years in ML/data/search or ranking systems, strong Python and software engineering skills, experience with cloud, distributed systems, and large-scale data.
Python, REST API, Pandas, NumPy, AWS Services, GCP, Kubernetes, Bedrock, Kafka, LangGraph, LangChain, AirFlow, MLFlow, TensorFlow, PyTorch, Scikit-learn, Qdrant, Docker, Git, CI/CD
1mo
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AI Principal Engineer
Boston or Hartford or Missouri
$192k-$240k/yr OnsiteFull Time
Voya Financial
Voya FinancialNYSE: VOYA: Provides retirement, investment, and insurance products and services.
Bachelor's in CS/Engineering/Math required (advanced degree preferred). Significant experience delivering production AI/ML systems, proficiency with Python/TypeScript/Rust, LLM and MLOps knowledge, model lifecycle and MLOps practices, and leadership of technical initiatives.
Python, TypeScript, Rust, LLM, MLOps
2mo
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Senior Software Engineer
O'Fallon, Missouri, United States
$115k-$184k/yr OnsiteFull Time
Mastercard
MastercardNYSE: MA: Global payment processing and financial technology service provider.
Python for AI components; Java for scalable services; experience with AI/ML lifecycle, microservices, databases, and distributed systems.
Python, Java, PyTorch, TensorFlow, Hugging Face, Docker, Kubernetes, CI/CD
1mo
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Principal Applied AI Engineer, Finance
Menlo Park or Boston or Indianapolis or Durham or Washington or Missouri or Rhode Island or Maine or New York or Florida or North Carolina or Massachusetts or Illinois or Tennessee or Pennsylvania or Mississippi or New Jersey or Maryland or Michigan or Vermont or Minnesota or West Virginia or Louisiana or California or Ohio or Connecticut or South Carolina or Georgia or Delaware or Wisconsin or Virginia or Kentucky or Indiana
$194k-$341k/yr RemoteFull Time
Genesys
Genesys: Provides AI-powered cloud platform for customer and employee experiences.
8+ YOE8+ years building production AI/ML systems with Python, LLMs, MLOps and cloud (preferably AWS); expertise in time-series forecasting, predictive modeling, and agentic/Generative AI; strong software engineering and CI/CD experience.
Python, LLMs, Docker, Kubernetes, AWS, CI/CD, APIs, MLOps, RAG, vector databases
1w
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Staff Software Engineer
St. Louis or Burlington
$111k-$166k/yr HybridFull Time
Merck
MerckXETRA: MRK: A science and technology providing healthcare, life science, and electronics solutions.
3+ YOEBachelor's in CS or related, 3+ years applied ML/data experience, strong Python and backend skills, experience with cloud, distributed systems, and large-scale data processing; leadership and mentoring experience preferred.
Python, REST API, Pandas, NumPy, AWS Services, GCP, Kubernetes, Bedrock, Kafka, LangGraph, LangChain, AirFlow, Qdrant, MLFlow, TensorFlow, PyTorch, Scikit-learn, Docker, Git, CI/CD
3w
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Senior Software Engineer Applied AI
Jefferson City, Missouri, United States
RemoteFull Time
AMC Health
AMC Health: Provides remote patient monitoring and virtual care technology.
7+ YOE7+ years building production backend systems, strong Python, cloud distributed systems experience, hands-on LLM/generative AI and ML lifecycle experience, disciplined data handling in regulated environments.
Python, AWS, LLMs, vector search, embeddings
1mo
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Senior AI Architect
Dallas or Vermont or Maryland or Rhode Island or Nebraska or Georgia or Florida or Pennsylvania or Virginia or Utah or New Mexico or Louisiana or Michigan or Colorado or Massachusetts or Illinois or Connecticut or Washington or Oklahoma or Indiana or Missouri or Ohio or Tennessee or Oregon or Delaware or Minnesota or Maine or Washington or South Dakota or Mississippi or North Dakota or California or New Hampshire or Iowa or Wyoming or Arkansas or Kentucky or Alabama or New York or Montana or New Jersey or West Virginia or South Carolina or Arizona or Wisconsin or Nevada or Kansas or North Carolina or Hawaii or Alaska or Texas or Idaho
$204k-$280k/yr HybridFull Time
o9 Solutions
o9 Solutions: Provides an AI-powered platform for integrated enterprise planning and operations.
15+ YOE15+ years engineering experience building production-grade AI/ML systems; expertise with LLMs, embeddings, vector architectures, and constraint-based planning; proven principal/lead architect experience and strong autonomy.
Large language models (LLMs), vector databases, Enterprise Knowledge Graph, constraint-based planning engines
2mo
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VP, Artificial Intelligence - Products & Services
Boston or Arizona or California or Colorado or Connecticut or District of Columbia or Florida or Georgia or Illinois or Indiana or Kansas or Massachusetts or Maryland or Maine or Michigan or Minnesota or Missouri or Mississippi or North Carolina or New Hampshire or New Jersey or New York or Ohio or Oregon or Pennsylvania or Rhode Island or South Carolina or Tennessee or Texas or Utah or Virginia or Vermont or Washington or Wisconsin or United States
$305k-$470k/yr RemoteFull Time
IDC
IDC: Provides market research and advisory services for technology industries.
7+ YOE3+ Mgmt7+ years applied ML/AI experience with 3+ years senior technical leadership; deep expertise in generative AI, LLMs, agentic systems; experience delivering AI products and building teams; strong communication skills.
LangChain, LlamaIndex, AutoGen, Python, SQL, AWS SageMaker, GCP Vertex AI, Azure ML
1mo
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Senior Insider Risk & AI Security Analyst/ Engineer IV
Arizona or Tempe or Missouri or St. Louis or United States
HybridFull Time
Edward Jones
Edward Jones: Offers investment management and financial planning through local branches.
5+ YOE5+ years in information systems security/IT with security controls; experience monitoring AI/ML platforms and telemetry; familiarity with UEBA, DLP, SIEM/SOAR; ability to investigate alerts, perform digital forensics, and translate AI risks for stakeholders.
Gurucul, XSOAR, Microsoft Purview, Proofpoint, Zscaler, SIEM, SOAR, UEBA, DLP
1mo
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Tech Product & Offering Dev Manager
New York City or Milwaukee or Dallas or Columbus or Kirkland or Cincinnati or Cleveland or Oklahoma City or Austin or Albany or Chicago or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Mountain View or Scottsdale or San Francisco or Morristown or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
$80k-$225k/yr HybridFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
5+ YOE5+ years in AI/ML/automation or software engineering, 5+ years Python and APIs/automation frameworks experience, 2+ years deploying AI/ML to production, bachelor’s degree or equivalent, experience with cloud/distributed systems and GenAI preferred.
Python, APIs, automation frameworks, data pipelines, GenAI, LLMs
1mo
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Senior AI Security Technical Architect
Tempe or St. Louis or Arizona or Missouri or United States
HybridFull Time
Edward Jones
Edward Jones: Offers investment management and financial planning through local branches.
12+ YOEBachelor's degree or equivalent experience; 12+ years in cybersecurity engineering/architecture; 4+ years securing AI/ML systems; experience with LLMs, RAG, ML pipelines, cloud security (Azure/AWS/GCP); strong communication and enterprise influence skills.
Azure, AWS, GCP, NIST AI Risk Management Framework (AI RMF), MITRE ATLAS, CIS, ISO 27001, LLM, Retrieval-Augmented Generation (RAG), vector databases