San Francisco • 50 milesRemote · Hybrid · Onsite · Field · All Environments
San Francisco • 50 milesRemote · Hybrid · Onsite · Field · All Environments
San Francisco • 50 milesRemote · Hybrid · Onsite · Field · All Environments
San Francisco • 50 milesRemote · Hybrid · Onsite · Field · All Environments
23 protein engineering jobs at 16 companies in San Francisco, CA
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Senior Scientist, Protein Engineering
South San Francisco, California, United States
$150k-$170k/yr OnsiteFull Time
4+ YOEPh.D. in relevant field, 4+ years post-academic biotech R&D experience in protein engineering, hands-on antibody/protein production and characterization, developability expertise, and strong communication and mentoring skills.
PyMOL, AlphaFold, ELN
1mo
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Research Associate, Protein Engineering
South San Francisco, California, United States
$80k-$115k/yr OnsiteFull Time
Bachelor's in chemistry/biochemistry/molecular biology, hands-on experience with protein expression and purification, assay development, molecular biology techniques, data analysis, and strong communication and collaboration skills.
FPLC, SDS-PAGE, UV/Vis, BCA, Next Generation DNA sequencing (NGS), liquid handling laboratory automation
3mo
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Senior Scientist - Experimental Protein Design for Target Discovery
South San Francisco, California, United States
$131k-$177k/yr OnsiteFull Time
PhD/MD/PharmD or advanced degree with protein design experience; 3+ years protein engineering with high-throughput workflows; strong communication and cross-functional collaboration.
1mo
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Postdoctoral Scholar – Protein Engineering and Bioconjugation for Cellular Force Microscopy
Berkeley, California, United States
$84k-$94k/yr OnsiteFull Time, Temporary
Ph.D. in a relevant field; experience with protein design, molecular cloning, protein expression, microbial culture, mutagenesis, and bioconjugation; strong written and oral communication; ability to work independently and in teams.
Infrared Force Microscope (IFM), Avalanching Nanoparticles (ANPs)
2d
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Scientist, Protein Sciences - San Carlos, California
San Carlos, California, United States
$137k-$171k/yr OnsiteFull Time
2+ YOERequires a biology, chemistry, engineering, or related degree with Ph.D. plus 2, M.S. plus 5, or B.S. plus 8 years of experience; expertise in protein expression, purification, construct design, and AKTA FPLC systems.
Electronic Lab Notebook (ELN), Unicorn, AlphaFold, AKTA FPLC, HPLC, LC/MS, X-ray crystallography (XRC), cryo-electron microscopy (cryo-EM), biomolecular NMR (bioNMR)
2mo
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Postdoctoral Scholar – Protein Engineering and Bioconjugation for Cellular Force Microscopy in Bay Area, California, United States
Berkeley, California, United States
$84k-$94k/yr OnsiteFull Time, Temporary
Ph.D. in a relevant field required. Experience in protein design/expression, molecular cloning, protein engineering, bioconjugation, and microbial culture handling. Strong communication, independent and team research skills; must have <3 years paid postdoctoral experience.
Infrared Force Microscope (IFM), Avalanching Nanoparticles (ANPs)
1mo
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Scientist II, ML - Guided Protein Design Evaluation
Emeryville, California, United States
$147k-$180k/yr HybridFull Time
5+ YOEPhD (or MS with equivalent industry experience) in molecular biology/related; 5+ years protein engineering and antibody discovery experience; strong NGS screening knowledge; ability to define assay QC and work across ML, bioinformatics, and experimental teams.
Python, pandas, SQL, LIMS
1mo
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Co-Op, LS AI, ML Scientist for Protein Engineering
San Francisco, California, United States
OnsiteInternship, Temporary
PhD student in a quantitative field with ML and computational biology research experience; strong Python programming and experience with PyTorch or JAX; ability to work with biological datasets and communicate results.
Python, PyTorch, JAX
6d
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Senior Scientist I, Antibody Engineering
San Mateo, California, United States
$160k-$185k/yr OnsiteFull Time
5+ YOEPh.D. in a relevant biological science, 5+ years of industry research, protein and antibody engineering expertise, mammalian cell culture, assays, protein characterization, data analysis, and strong communication skills.
machine learning, synthetic biology, AI/ML, agentic software tools
3w
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Junior Specialist / Assistant Specialist - Chemical and Biomolecular Engineering - College of Chemistry
Berkeley, California, United States
$57k-$66k/yr OnsiteFull Time
Bachelor's degree required. Perform molecular cloning, protein expression and purification, structural biology (EM/X-ray), cell culture, biochemical assays, and data analysis in a research lab.
PCR, Gibson assembly, SDS-PAGE, Western blotting, FPLC, flow cytometry, fluorescence microscopy, cryo-electron microscopy, X-ray crystallography
3mo
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Associate Scientist/Scientist/Senior Scientist in Antibody Development
San Francisco, California, United States
$100k-$160k/yr OnsiteFull Time
5+ YOE5+ years industry experience designing, producing, and optimizing developability of multi-specific antibodies; strong background in biochemistry/protein engineering.
Phage Display, Yeast Display, Molecular Biology, Biochemistry, Protein Engineering, In Vitro Assays, In Vivo Studies, CRO Management
2mo
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Postdoctoral Fellow - Analytical Development & Quality Control, Bouvarel & Camperi Labs
South San Francisco, California, United States
$100k-$107k/yr OnsiteFull Time
Ph.D. in Analytical Chemistry, Biochemistry, or Chemical Engineering; experience with UHPLC-MS, protein/nucleic acid characterization; strong publications; cross-functional collaboration skills.
UHPLC-MS, HRMS, Orbitrap, BioPharma Finder, Byos, Chromeleon
4w
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Bioinformatics Engineer - Function
San Francisco, California, United States
$120k-$180k/yr HybridFull Time
Hands-on experience in functional biology or related fields; experience with functional-assay data or computational protein design; quantitative modeling skills; proficiency in Python and/or R; familiarity with binding, stability, immune escape, viral fitness, toxin potency, or protein design.
Python, R
2mo
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Senior / Staff Scientist – Binder Discovery
San Francisco, California, United States
OnsiteFull Time
3+ YOEPhD in Biochemistry, Molecular Biology, Protein Engineering, or related field; 3+ years lab experience; experience with display technologies; binding assays; cloning and library construction; strong collaboration.
Phage display, Yeast display, ELISA, Flow cytometry, BLI, SPR, Cloning, Mutagenesis, Protein expression, Purification, Mass spectrometry
1mo
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Principal Scientist
San Carlos, California, United States
$165k-$205k/yr OnsiteFull Time
8+ YOEPhD preferred (or MS/BS with extensive experience). 8+ years post-PhD (or equivalent), strong antibody/protein engineering, expression/purification, molecular biology, project leadership, publications/patents, and experience mentoring staff and managing collaborations.
1mo
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Founding ML Engineer
San Francisco, California, United States
$150k-$300k/yr OnsiteFull Time
Experienced in biomolecular modeling and ML for drug discovery; ability to fine-tune protein/structure models, build ML systems that integrate with wet-lab workflows, and evaluate model impact on drug development.
ESM, AlphaFold-family models, RFdiffusion, ProteinMPNN
2mo
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Senior Manager, External Manufacturing
Newark or South San Francisco
$155k-$180k/yr OnsiteFull Time
8+ YOEBachelor's in science/engineering, minimum 8 years GMP pharmaceutical manufacturing experience, CDMO/external manufacturing experience, RNA/protein or cell/gene therapy experience preferred, CMC/regulatory knowledge, leadership and financial acumen, ability to travel up to 20%, U.S. work authorization required.
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