32 upstream jobs at 10 companies in Graham, NC
3mo
Save
Mark Applied
Hide
Manufacturing Lead Upstream - Days
Research Triangle Park, North Carolina, United States
OnsiteFull Time
4+ YOE4+ years cGMP manufacturing experience (varies by degree), knowledge of SOPs/CGMP, experience with unit operations (e.g., chromatography, UFDF), ability to perform physical tasks and respirator-protected work.
2w
Save
Mark Applied
Hide
Upstream Process Development Associate I/II
Durham, North Carolina, United States
$50k-$70k/yr OnsiteFull Time
1+ YOEBachelor's (1–3+ years) or Master's (2+ years) in Chemical Engineering/Biotechnology, mammalian cell culture experience, MS Office proficiency, GDP and DOE/JMP experience, weekend/holiday flexibility.
Microsoft Excel, Microsoft PowerPoint, Microsoft Word, Design Expert, JMP
1mo
Save
Mark Applied
Hide
Specialist Manufacturing – Process Owner - Upstream / Downstream / Services
Holly Springs, North Carolina, United States
$108k-$146k/yr OnsiteFull Time
2+ YOETechnical expertise in upstream/downstream/manufacturing services, GMP experience, MES/EBR familiarity, process ownership, troubleshooting, SOP authoring; degree and biotech operations experience required (varies by degree).
Manufacturing Execution Systems (MES), Electronic Batch Record (EBR)
1w
Save
Mark Applied
Hide
Scientist - Upstream Cell Culture
Durham, North Carolina, United States
$94k-$174k/yr OnsiteFull Time
0+ YOEBachelor's with 4–6 years, master's with 2–4 years, or PhD with 0–2 years in a relevant technical field; requires mammalian biologics production, cell culture, bioreactor, purification, statistical analysis, and DoE experience.
Design of Experiment (DoE), Bill of Materials (BOM), Standard Operating Procedures (SOPs), AAV, LVV
1w
Save
Mark Applied
Hide
Scientist - Upstream Cell Culture
Durham, North Carolina, United States
$94k-$174k/yr OnsiteFull Time
4+ YOERequires a bachelor's degree with 4–6 years, master's with 2–4 years, or PhD with 0–2 years relevant experience; mammalian cell culture, bioreactors, viral/biologic production, purification, DoE, QbD, and statistical analysis.
AAV, LVV, DOE, QbD, Bill of Materials (BOM), Standard Operating Procedures (SOPs)
6d
Save
Mark Applied
Hide
Manufacturing Manager, Bioprocessing
Durham, North Carolina, United States
OnsiteFull Time
5+ YOE1+ MgmtBachelor's degree in science, engineering, manufacturing operations, or related field; 5+ years of bioprocessing experience; upstream or downstream operations experience. Leadership experience preferred.
Tangential Flow Filtration (TFF), chromatography, Lean Manufacturing, Six Sigma, Operational Excellence
1mo
Save
Mark Applied
Hide
Sr. Open-Source Software Engineer - Apache Cassandra (Morrisville, NC, US)
Morrisville or San Jose or Raleigh or Boston or Seattle
$220k-$265k/yr HybridFull Time
12+ YOEApache Cassandra committer with 12+ years software engineering experience, expert Java in distributed systems, upstream contribution and release management, strong written communication and mentoring skills.
Apache Cassandra, Java, GitHub, Apache Jira, GoCQL, Spark
1w
Save
Mark Applied
Hide
Cell Culture Modality Leader Central and SoutheastUS
Logan or Chicago or Minneapolis or Atlanta or Austin or Indianapolis or Raleigh or Madison
$130k-$160k/yr RemoteFull Time
10+ YOEBachelor's degree in life sciences, biotechnology, engineering, or related field; 10+ years in biotechnology, biopharma, or life sciences; team leadership, upstream bioprocessing, consultative sales, and strategic planning experience.
Salesforce.com, Miller Heiman, SPIN, Danaher Business System (DBS)
2w
Save
Mark Applied
Hide
Process Engineer II
Durham, North Carolina, United States
OnsiteFull Time
2+ YOEBachelor's in a scientific discipline with 2+ years biopharma experience or Master's degree or HS with 6+ years; hands-on upstream/downstream biomanufacturing experience, strong communication, DOE familiarity, willing to travel ~10%.
Microsoft Word, Microsoft Excel, Microsoft PowerPoint, JMP Statistical Software
2mo
Save
Mark Applied
Hide
Senior Manufacturing Operator
Sanford or Princeton or Mississauga or California or North Carolina
$33-$45/hr OnsiteFull Time
4+ YOEHands-on GMP biopharmaceutical manufacturing experience executing upstream/downstream processes, equipment commissioning/validation, cGMP and data integrity adherence, PCS/MES/ERP/LIMS proficiency, SOP development, troubleshooting, and training.
ERP, LIMS, MES, PCS, QMS, BMS, DeltaV, Unicorn, Ignition, Microsoft Office
2w
Save
Mark Applied
Hide
Process Engineer II
Durham, North Carolina, United States
OnsiteFull Time
2+ YOESupport process scale-up, technology transfer, process characterization and PPQ readiness; 2+ years biopharma experience or advanced degree; hands-on upstream/downstream lab experience; strong communication and Microsoft Office skills.
Microsoft Word, Microsoft Excel, Microsoft PowerPoint, JMP Statistical Software
1mo
Save
Mark Applied
Hide
Sr. Open Source Software Engineer (Kafka)
San Jose or Raleigh or Waltham or Seattle or Cork or Schiphol
$220k-$265k/yr HybridFull Time
12+ YOE12+ years software engineering experience, Apache Kafka committer status, expert Java skills, deep Kafka internals knowledge, strong written communication, ability to lead KIP-level design and upstream contributions.
Apache Kafka, Kafka Streams, Kafka Connect, MirrorMaker 2, Java, Jira, Kubernetes
3w
Save
Mark Applied
Hide
Technical Application Specialist, Downstream Biopharm Materials - Research Triangle Park
Burlington or Research Triangle Park or North Carolina or South Carolina or Georgia or Florida or Texas
$86k-$178k/yr FieldFull Time
5+ YOEBachelor's in chemical engineering/biochemistry,5+ years biopharma process development experience,2+ years customer-facing technical/commercial experience,knowledge of upstream/downstream operations and regulatory impact,excellent communication and presentation skills.
CRM