14 upstream jobs at 5 companies in Spring Lake, NC
1mo
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Specialist Manufacturing – Process Owner - Upstream / Downstream / Services
Holly Springs, North Carolina, United States
$108k-$146k/yr OnsiteFull Time
2+ YOETechnical expertise in upstream/downstream/manufacturing services, GMP experience, MES/EBR familiarity, process ownership, troubleshooting, SOP authoring; degree and biotech operations experience required (varies by degree).
Manufacturing Execution Systems (MES), Electronic Batch Record (EBR)
1mo
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Automation Engineer 3, DSM Upstream
Holly Springs, North Carolina, United States
OnsiteFull Time
5+ YOEBachelor's in engineering, 5+ years automation/controls experience, DeltaV experience required, EM document and testing experience, effective communication and problem-solving skills.
DeltaV
2mo
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Process Engineer - Solution Prep, Upstream, and Downstream
Holly Springs, North Carolina, United States
$88k-$119k/yr OnsiteFull Time
2+ YOEDegree in engineering (multiple education/experience alternatives) plus 2+ years engineering experience (min). Must support GMP biopharmaceutical commissioning, qualification, troubleshooting, and 24/7 operational coverage; up to 10% travel.
Data Analytics, Root Cause Analysis (RCA), Statistical Process Control (SPC), Six Sigma, Predictive Maintenance
1w
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Manufacturing Associate, Bulk Drug Substance Upstream - Days
Holly Springs, North Carolina, United States
$71k-$96k/yr OnsiteFull Time
0+ YOERequires a high school diploma/GED plus 2 years of regulated manufacturing experience, an associate degree plus 6 months of experience, or a bachelor's degree. cGMP, teamwork, and communication skills required.
Electronic Batch Records (EBRs), MES, DeltaV
1mo
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Manufacturing Associate, Bulk Drug Substance Upstream - Days
Holly Springs, North Carolina, United States
$71k-$96k/yr OnsiteFull Time
0+ YOEHigh School/GED + 2 yrs manufacturing (or Associate + 6 months, or Bachelor’s), experience in regulated/cGMP environments, proficiency with EBR/MES/Delta V and Microsoft Office, strong communication and desire to learn.
Electronic Batch Records (EBR), MES, Delta V, Microsoft Office, Electronic Quality Systems
2mo
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Senior Process Engineer - Solution Prep, Upstream, and Downstream
Holly Springs, North Carolina, United States
$115k-$156k/yr OnsiteFull Time
4+ YOEQualifications include advanced degree or equivalent experience (Doctorate OR Master’s +2 yrs OR Bachelor’s +4 yrs OR Associate +8 yrs OR HS +10 yrs). Preferred: chemical/mechanical engineering, 6+ yrs relevant with 5+ yrs in biopharma ops, GMP equipment experience, tech transfer, commissioning/qualification, regulated environment experience, and o...
weigh and dispense equipment, solution preparation vessels, cell culture reactors, centrifugation, chromatography, viral filtration skids, UFDF skids, autoclaves, clean in place (CIP) systems, clean steam, water for injection
1mo
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Specialist Manufacturing New Product Introduction (NPI): Upstream Readiness
Holly Springs, North Carolina, United States
$108k-$146k/yr OnsiteFull Time
2+ YOEBiologics drug substance manufacturing experience, cross-functional project management, technical writing, GMP operations knowledge, and 2+ years biotechnology operations experience (varies by degree).
6d
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Senior Associate Manufacturing - Technical Training - Upstream Bulk Drug Substance
Holly Springs, North Carolina, United States
$86k-$116k/yr OnsiteFull Time
0+ YOEMaster's degree, or qualifying education and manufacturing experience; preferred biotech or pharmaceutical experience, training development, LMS, technical writing, quality systems, project management, and communication skills.
Learning Management System (LMS), Track Wise, Veeva
1mo
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Manufacturing Associate 3 (Upstream)- Night Shift (2-2-3)
Holly Springs, North Carolina, United States
OnsiteFull Time
2+ YOEHigh school/GED plus manufacturing experience or associate/BS in related field; 2+ years cGMP manufacturing experience preferred; knowledge of unit operations, cGMP, safety, and troubleshooting.
1mo
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Sr. Open-Source Software Engineer - Apache Cassandra (Morrisville, NC, US)
Morrisville or San Jose or Raleigh or Boston or Seattle
$220k-$265k/yr HybridFull Time
12+ YOEApache Cassandra committer with 12+ years software engineering experience, expert Java in distributed systems, upstream contribution and release management, strong written communication and mentoring skills.
Apache Cassandra, Java, GitHub, Apache Jira, GoCQL, Spark
1w
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Cell Culture Modality Leader Central and SoutheastUS
Logan or Chicago or Minneapolis or Atlanta or Austin or Indianapolis or Raleigh or Madison
$130k-$160k/yr RemoteFull Time
10+ YOEBachelor's degree in life sciences, biotechnology, engineering, or related field; 10+ years in biotechnology, biopharma, or life sciences; team leadership, upstream bioprocessing, consultative sales, and strategic planning experience.
Salesforce.com, Miller Heiman, SPIN, Danaher Business System (DBS)
2mo
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Senior Manufacturing Operator
Sanford or Princeton or Mississauga or California or North Carolina
$33-$45/hr OnsiteFull Time
4+ YOEHands-on GMP biopharmaceutical manufacturing experience executing upstream/downstream processes, equipment commissioning/validation, cGMP and data integrity adherence, PCS/MES/ERP/LIMS proficiency, SOP development, troubleshooting, and training.
ERP, LIMS, MES, PCS, QMS, BMS, DeltaV, Unicorn, Ignition, Microsoft Office
2mo
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Senior Manufacturing Systems Engineer – DeltaV Batch
Holly Springs, North Carolina, United States
$137k-$185k/yr OnsiteFull Time
2+ YOELead automation engineering projects for upstream/downstream/solution prep using Emerson DeltaV DCS; support commissioning/qualification, 24/7 operational support, troubleshooting, SOP/cGMP documentation, and mentor engineering staff.
Emerson DeltaV, Distributed Control System (DCS), OPC, Foundation Fieldbus, Profibus
1mo
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Sr. Open Source Software Engineer (Kafka)
San Jose or Raleigh or Waltham or Seattle or Cork or Schiphol
$220k-$265k/yr HybridFull Time
12+ YOE12+ years software engineering experience, Apache Kafka committer status, expert Java skills, deep Kafka internals knowledge, strong written communication, ability to lead KIP-level design and upstream contributions.
Apache Kafka, Kafka Streams, Kafka Connect, MirrorMaker 2, Java, Jira, Kubernetes