64 ai program manager jobs at 24 companies in O'Fallon, MO

PromotedHiringCafe
Founding Machine Learning / AI Search Engineer
Cupertino, CA, US
$160k-$310k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Build the ML and AI search behind HiringCafe — ranking, recommenders, retrieval, and LLM agents that surface jobs people would never find on their own.
Python, PyTorch, Elasticsearch, LLMs
3w
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Responsible AI Program Lead (Exempt)
Chesterfield, Missouri, United States
RemoteFull Time
Mercy
Mercy: Integrated health care system providing hospital and clinical services.
2+ YOEBachelor's degree in a related field, 2-3 years program management/governance or related experience, experience supporting AI/technology governance, documentation and stakeholder coordination, strong communication skills.
3w
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Principal, Technical Program Manager
O'Fallon, Missouri, United States
$152k-$258k/yr OnsiteFull Time
Mastercard
MastercardNYSE: MA: Global payment processing and financial technology service provider.
Proven technical program management experience, strong leadership and communication, vendor and cloud experience, familiarity with AI best practices, strategy and execution skills, ability to deliver complex global programs.
1w
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Project Manager - AI Initiatives
St. Louis, Missouri, United States
HybridFull Time
RubinBrown
RubinBrown: Accounting and consulting firm providing audit and tax services.
10+ YOE10+ years program/project management experience including AI initiatives; Bachelor's degree preferred; experience with change management, vendor management, AI/ML concepts, and presenting to executive leadership.
LLMs
3d
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Program Analyst (Senior Program Analyst)
Fresno or Oakland or Denver or Washington or Jacksonville or Atlanta or Chamblee or Indianapolis or Covington or Andover or Baltimore or Lanham or Kansas City or Saint Louis or Cheektowaga or Holtsville or Cleveland or Portland or Philadelphia or Pittsburgh or Guaynabo or Franklin or Memphis or Austin or Dallas or Ogden or Richmond or Seattle or Martinsburg
$126k-$197k/yr OnsiteFull Time
IRS Office of Chief Counsel
IRS Office of Chief Counsel: Represents the IRS in tax litigation and legal matters.
1+ YOEOne year specialized experience at GS-13 equivalent analyzing program effectiveness, leading major analytical projects, using resource management methods, working with tax laws, and presenting findings.
XML Spy, AI, PowerBI
1mo
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Technical Commerce & AI Manager | Agentic Commerce
Chicago or Milwaukee or Herndon or Dallas or Columbus or Kirkland or Irvine or Cincinnati or New York City or Cleveland or Oklahoma City or Austin or Albany or Arlington or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Mountain View or Scottsdale or Morristown or San Francisco or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
$80k-$266k/yr OnsiteFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
8+ YOE8+ years delivering digital commerce or marketing-technology transformations; hands-on Python and SQL experience; experience with Generative/Agentic AI, Agentic AI frameworks, cloud deployments (AWS/Azure/GCP), FastAPI, Databricks, CI/CD and Kubernetes; consulting and stakeholder leadership.
Python, SQL, LangChain, LlamaIndex, CrewAI, AutoGen, LangGraph, FastAPI, Databricks, AI/BI Genie, LLM-as-a-Judge, Mosaic AI Gateway, Redis, Kubernetes, CI/CD, AWS, Azure, GCP, Adobe Commerce, SAP CX, Salesforce Commerce, MCP
4d
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AI Project Manager – Home Lending Delivery
Earth City or Hopkins
$112k-$131k/yr HybridFull Time
U.S. Bank
U.S. BankNYSE: USB: Provider of personal, business, and institutional financial services.
10+ YOEMaster's degree or equivalent experience,10+ years project management experience,experience in regulated financial services,SDLC/Agile knowledge,portfolio tools (Jira,Daptiv),PMP/Agile/SAFE certs preferred.
Jira, Daptiv
3d
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AI Engineering Lead
Columbia, Illinois, United States
HybridFull Time
Automotive Product Consultants
Automotive Product Consultants: Provides sales, finance, and insurance services to automotive dealerships.
Proven experience integrating LLMs into production, prompt engineering, RAG, Python or .NET (C#), vector DBs, cloud AI services, and leading cross-functional AI programs.
Anthropic Claude, OpenAI, Claude Code, GitHub Copilot, Python, .NET (C#), Pinecone, pgvector, AWS Bedrock, Amazon SageMaker, Twilio, Amazon Connect, IVR
5d
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Associate Client Solutions Director- Digital & AI Platforms (St. Louis, MO)
United States or St. Louis
$134k-$168k/yr RemoteFull Time
World Wide Technology
World Wide Technology: Global technology solutions provider and systems integrator.
10+ YOE3+ Mgmt10+ years applicable experience with 3+ years as a client-facing director/manager; proven account growth, program financial ownership, and experience leading digital/AI transformation programs; bachelor's degree.
AI/ML, GenAI, APIs, microservices
1mo
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Senior Manager, Digital Transformation
St. Louis, Missouri, United States
HybridFull Time
Armanino
Armanino: Provides accounting, tax, and consulting services to diverse organizations.
8+ YOE8+ years in consulting or enterprise transformation; strong enterprise architecture and digital/AI experience;Bachelor's; lead multi-workstream programs; executive communication; able to work in offices or client sites up to 50%.
ERP, CRM, AI platforms, Data platforms, Workflow tools
1w
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Engagement Senior Manager
Everett or Seattle or Plano or Berkeley or Renton or Mesa or North Charleston
$191k-$277k/yr HybridFull Time
Boeing
BoeingNYSE: BA: Designs and manufactures aircraft, defense systems, and space technology.
10+ YOE5+ Mgmt10+ years executive presentation experience, 5+ years leading AI deployments and customer-facing program management, ability to travel 10–20%, conflict-of-interest assessment and drug testing required.
2mo
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Chief of Staff to the Managing Director of AI
St. Louis or United States or Canada
RemoteFull Time, Contract
Human Agency
Human Agency: Provides human-centered AI consulting and venture building services.
5+ YOE5-7+ years in operations, client services, or program management with client-facing delivery; strong AI fluency; proven ability to design scalable processes; experience with no/low-code automation and modern AI tooling; excellent executive communication.
Google Workspace, Asana, Notion, Slack, Zapier, n8n, Airtable
3w
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Manager, Delivery Services (Hybrid)
Chesterfield or St. Louis or Alabama or California or Florida or Georgia or Illinois or Missouri or Michigan or North Carolina or New Jersey or New York or Texas or Washington
HybridFull Time
IMPACT Group
IMPACT Group: Provides career coaching, relocation support, and outplacement services.
2+ MgmtBachelor's degree or equivalent, 2+ years supervisory experience, proven coaching and performance management skills, proficiency with Microsoft Office, experience using metrics and reporting, comfort with technology and AI-enabled tools.
Microsoft Office
2w
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Manager, Field Engineering - MFG
Texas or Illinois or St. Louis
$173k-$237k/yr RemoteFull Time
Databricks
Databricks: A unified platform for data analytics and artificial intelligence.
7+ YOE3+ Mgmt3+ years leading technical pre-sales teams, 7+ years in Data + AI, ability to hire/coach SAs, technical competence in data/AI architectures, trusted advisor to technical executives.
Apache Spark, Delta Lake, MLflow
2mo
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Senior Technical Success Manager, Majors - East Region
New York City or Arlington or Atlanta or Austin or Boston or Charlotte or Chicago or Dallas or Hartford or Houston or Indianapolis or Kansas City or Minneapolis or Nashville or New Haven or New York or Philadelphia or Raleigh or St Louis or Remote East
RemoteFull Time
Amplitude
AmplitudeNasdaq: AMPL: Develops digital analytics software for tracking customer product behavior.
5+ YOE5+ years in Customer Success/Technical Account Management; 2+ years leading enterprise software deployments with data governance; 2+ years managing 10+ major/enterprise accounts; renewals and expansions experience.
Amplitude platform, AI agents, data architecture, instrumentation, data governance
2mo
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Senior Project Manager
Columbia or Kansas City or Minneapolis or St. Louis
HybridFull Time
Coegi
Coegi: Provides data-driven digital media strategy and programmatic advertising services.
2+ YOETwo+ years agency experience in digital campaigns; strong Asana/Harvest; paid media platforms; PMP certification a plus.
Asana, Harvest, The Trade Desk, DV360, Meta Ads Manager, LinkedIn, Microsoft Office, Google Workspace, AI tools
2mo
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Lead Project Manager
Bridgeton, Missouri, United States
OnsiteFull Time
Cass Information Systems
Cass Information SystemsNASDAQ: CASS: Provides invoice processing and payment services for large corporations.
7+ YOE5+ MgmtLead enterprise Agile programs; AI-enabled delivery; PMP and SAFe SPC/SAFe Fellow; 7+ years PM, 5+ years Agile leadership; AI governance and analytics experience.
Azure Dev Ops, AI analytics, enterprise Agile platforms
1d
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Microsoft AI Senior Solutions Architect
Saint Louis, Missouri, United States
$160k-$190k/yr OnsiteFull Time
Perficient
Perficient: Provides digital transformation and AI consulting for global enterprises.
10+ YOE10+ years in the Microsoft ecosystem, 8+ years consulting, experience leading large transformation programs, strong Microsoft AI/Copilot/Azure AI knowledge, enterprise adoption and change management, excellent communication and mentoring skills.
Microsoft 365 Copilot, Copilot Studio, Agent 365, Dynamics Agents, Fabric, Azure AI, M365
5d
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Sr. Director Engagement Leader
Tempe or St. Louis
RemoteFull Time
Edward Jones
Edward Jones: Offers investment management and financial planning through local branches.
6+ YOE6+ years experience, bachelor’s in business/strategy/analytics/engineering or related, experience leading AI/analytics/digital initiatives, program/engagement/product delivery skills, governance and stakeholder management.
3mo
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Payer Back Office Strategy / Technology / Operations Consultant, Senior Associate
Boston or Indianapolis or Raleigh or Charlotte or Jacksonville or Chicago or Cincinnati or Cleveland or Columbia or Kansas City or Los Angeles or Baltimore or Birmingham or St. Louis or Salt Lake City or San Diego or San Francisco or Silicon Valley or Seattle or Stamford or Tampa or Toledo or Austin or Washington or Melville or Miami or Denver or Des Moines or Nashville or Detroit or New Orleans or New York or Florham Park or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Houston
$77k-$202k/yr OnsiteFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
3+ YOEBachelor’s degree and 3 years of experience; Master’s degree preferred; strong payer operations, data analytics, automation, and AI skills; willingness to travel up to 80%.
Data Analytics, Automation, Artificial Intelligence
3w
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Business Transformation Manager
St. Louis or Chesterfield
$100k-$165k/yr HybridFull Time
Anders CPAs + Advisors
Anders CPAs + Advisors: Provides professional accounting, tax, audit, and advisory services.
6+ YOE6–12 years consulting or transformation experience; bachelor's in business or technology required; proven client leadership, project and program management, AI advisory, and coaching skills; preferred credentials include PMP, Lean Six Sigma, Prosci, TOC, CPA/CMA, or MBA.

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