720 applied jobs at 348 companies in Brookline, MA

2d
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Head of Applied AI
Boston, Massachusetts, United States
OnsiteFull Time
Physical Superintelligence
Physical Superintelligence: Building AI systems to discover new physics at scale.
8+ YOE8+ years applying ML and simulation to commercial engineering problems, experience leading customer-facing technical teams, strong applied-ML and computational skills, physics/engineering literacy, and experience owning customer-facing tools or interfaces.
OpenFOAM, Ansys, COMSOL
1w
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Applied Researcher II
San Jose or San Francisco or McLean or Cambridge or New York City
$286k-$327k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: Financial services offering credit cards, banking, and loans.
2+ YOEPhD (or MS+experience) in CS/EE/Math or related, 2+ years applied research experience, expertise building large deep learning models, publications or open-source contributions, and ability to deliver models at scale.
PyTorch, AWS Ultraclusters, Huggingface, Lightning, VectorDBs, pytorch-geometric, DGL
5d
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Staff Applied Scientist, AdTech
Arlington or Baltimore or Buffalo or Jersey City or Manchester or New York City or Philadelphia or Stamford
$175k-$200k/yr RemoteFull Time
Launch Potato
Launch Potato: Digital media operating a portfolio of consumer brands.
5+ YOE5+ years applied data science experience building and deploying ML solutions in AWS for adtech or performance marketing; expert Python and SQL; strong modeling and business-first orientation.
Python, SQL, AWS, Looker, Google, Meta
4d
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Senior Applied Scientist , Amazon Ads
Boston or Sunnyvale or New York City or Bellevue or Seattle or Arlington or New York or Santa Monica or Washington or Palo Alto
$167k-$260k/yr OnsiteFull Time
Amazon
AmazonNASDAQ: AMZN: Global online retail and cloud computing technology provider.
5+ YOEPhD or Master's+experience in applied ML, 5+ years building ML models, strong programming in Python/Java/C++, deep learning experience, large-scale systems experience.
Python, Java, C++, scikit-learn, TensorFlow, PyTorch, Spark MLLib, MxNet, numpy, scipy, Hadoop, Spark
1mo
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Applied AI Engineer, Internal Tools
Boston or Milwaukee or Maitland
$104k-$178k/yr HybridFull Time
Alegeus
Alegeus: Provides technology platforms for managing healthcare benefit accounts.
3+ YOE3+ years building applied AI/automation/internal tools; experience with ChatGPT, Microsoft Copilot, APIs, and structured data; strong prototyping, productization, and cross-functional collaboration; Bachelor's in related field or equivalent experience.
ChatGPT, Microsoft Copilot, APIs
1mo
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Applied AI Research Engineer
Boston or San Francisco or United States
HybridFull Time
Code Metal
Code Metal: Verifiable AI-powered code translation for mission-critical industries.
3+ YOEBachelor's or Master's in a technical field (or equivalent), 3+ years building AI/ML or applied research systems, strong Python and PyTorch skills, experience with LLM tooling, fine-tuning, retrieval, agentic systems, and experiment design; eligible to obtain U.S. security clearance.
Python, PyTorch, Transformers, vLLM, Hugging Face
2w
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Applied AI Engineer
Louisville or Dallas or Boston or New York City or Washington
$142k-$196k/yr OnsiteFull Time
Humana
HumanaNYSE: HUM: Provides health insurance plans and clinical healthcare services.
5+ YOEBachelor's or Master's in quantitative field plus 3–5+ years software engineering; 5+ years Python production experience, LLM integration, API design, cloud, containers, CI/CD, and strong software engineering fundamentals.
Python, FastAPI, Flask, AWS, Google Cloud, Azure, Docker, Kubernetes, CI/CD, Git, Claude Code, Cursor, GitHub Copilot agents, LangChain, LlamaIndex, Pydantic AI, Kafka, OpenTelemetry, LangSmith, Arize, Terraform, Pulumi
1w
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Applied AI Engineer
Boston, Massachusetts, United States
$88k-$168k/yr HybridFull Time
SOPHiA GENETICS
SOPHiA GENETICSNASDAQ: SOPH: Develops AI platforms for genomic and clinical data analysis.
5+ YOE5+ years senior engineering or product experience building and shipping AI-enabled products, strong hands-on software skills, LLM and modern AI tooling fluency, cross-functional change management, and product/engineering best practices.
LLMs, SOPHiA DDM Platform, SCRUM
2w
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Sr. Applied Research Engineer
Burlington, Massachusetts, United States
$119k-$148k/yr OnsiteFull Time
Glaukos
GlaukosNYSE: GKOS: Develops therapies and devices for treating chronic eye diseases.
5+ YOEPhD or MS/BS with equivalent experience in mechanical/biomedical engineering or physics; 5–8+ years in soft-tissue biomechanics, computational modeling, finite element analysis, biomechanical imaging, and algorithm development; COMSOL experience preferred.
COMSOL Multiphysics
1w
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Senior Applied AI Engineer
Marlborough or San Diego
$100k-$130k/yr HybridFull Time
Hologic
HologicNASDAQ: HOLX: Develops medical technology for women's healthcare and diagnostics.
5+ YOE5+ years engineering experience with 2+ years building AI/ML or automation solutions; strong programming (Python, JavaScript/TypeScript, C#); Azure and modern LLM experience; stakeholder communication and production deployment track record.
Azure OpenAI, Azure, Claude, Microsoft Copilot, Python, JavaScript/TypeScript, C#, Power Automate, Logic Apps, LangGraph, Semantic Kernel, Model Context Protocol (MCP), OpenAI, Gemini, Microsoft Power Platform
1mo
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Machine Learning Applied Researcher - Speech, Vision and Audio
Cambridge, Massachusetts, United States
OnsiteFull Time
Apple
AppleNASDAQ: AAPL: Designs and sells consumer electronics, software, and online services.
Conduct applied research in machine learning for speech, vision, and audio to develop new products and features.
3d
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Applied AI Research Engineer - Model Cost Optimization
Cambridge, Massachusetts, United States
$210k-$260k/yr OnsiteFull Time
Blitzy
Blitzy: Autonomous AI platform for enterprise software development.
Applied ML/AI research experience with hands-on LLM evaluation or fine-tuning, strong software engineering, familiarity with LLM evaluation and benchmarking, and understanding of inference cost/latency tradeoffs.
LLM
1mo
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Applied AI Engineer, Founding Team
New York City or Milwaukee or Dallas or Columbus or Kirkland or Cincinnati or Cleveland or Oklahoma City or Austin or Albany or Chicago or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Mountain View or Scottsdale or San Francisco or Morristown or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
$63k-$219k/yr OnsiteFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
5+ YOE5+ years in software engineering/AI/enterprise tech; 1+ year building hybrid retrieval systems and agentic AI (Claude/Anthropic); experience with MCP servers; ability to translate AI concepts; Bachelor's degree or equivalent.
Anthropic, Claude, Model Context Protocol (MCP), Oracle 23ai, Oracle, Oracle Cloud Infrastructure (OCI), EPM, ERP
1mo
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Principal Applied AI Engineer, Finance
Menlo Park or Boston or Indianapolis or Durham or Washington or Missouri or Rhode Island or Maine or New York or Florida or North Carolina or Massachusetts or Illinois or Tennessee or Pennsylvania or Mississippi or New Jersey or Maryland or Michigan or Vermont or Minnesota or West Virginia or Louisiana or California or Ohio or Connecticut or South Carolina or Georgia or Delaware or Wisconsin or Virginia or Kentucky or Indiana
$194k-$341k/yr RemoteFull Time
Genesys
Genesys: Provides AI-powered cloud platform for customer and employee experiences.
8+ YOE8+ years building production AI/ML systems with Python, LLMs, MLOps and cloud (preferably AWS); expertise in time-series forecasting, predictive modeling, and agentic/Generative AI; strong software engineering and CI/CD experience.
Python, LLMs, Docker, Kubernetes, AWS, CI/CD, APIs, MLOps, RAG, vector databases
1mo
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Applied AI Engineer/Architect
Boston or Chicago or Dallas or Los Angeles or Minneapolis or New York City or San Francisco or Seattle or Washington, D.C.
$225k-$304k/yr OnsiteFull Time
West Monroe
West Monroe: Business and technology consultancy specializing in digital transformation.
7+ YOE7+ years in software/data/ML/AI or architecture with hands-on AI engineering; strong Python plus TypeScript/Java/C# experience; experience with LLMs, RAG, agents, MLOps, and hyperscaler AI platforms; ability to work in US without sponsorship.
LLMs, agents, RAG, ChatGPT, Python, TypeScript, Java, C#, Azure OpenAI, AWS Bedrock, Google Vertex AI, Databricks, Snowflake, Microsoft Fabric, MLOps, APIs
5d
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Applied AI and Machine Learning Scientist (Director)
Cambridge, Massachusetts, United States
$177k-$294k/yr HybridFull Time
Pfizer
PfizerNYSE: PFE: Develops and manufactures vaccines and medicines for global healthcare
9+ YOEAdvanced degree preferred; ~9+ years relevant experience; demonstrated leadership in applied AI for drug discovery; strong knowledge of LLMs, foundation models, multimodal AI, and governance; ability to prioritize use cases and drive adoption.
LLMs, foundation models, agentic systems, multimodal AI, retrieval-augmented
4w
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Senior Applied AI/ML Engineer
Cambridge, Massachusetts, United States
OnsiteFull Time
TetraScience
TetraScience: Cloud platform for automating and harmonizing scientific research data.
10+ YOEAdvanced degree in Biological, Data, or Computer Science; 10+ years AI/ML development experience (or 5+ in commercial life sciences); portfolio of end-to-end AI/ML products; proven deployment experience; strong communication.
Tetra OS, Databricks, Snowflake, NVIDIA, Google, Microsoft
2mo
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Applied AI & Analytics Associate Opportunities
Needham, Massachusetts, United States
$100k-$125k/yr HybridFull Time
SharkNinja
SharkNinjaNYSE: SN: Designs and sells household appliances and beauty technology products
2+ YOE2+ years analytics or data science; hands-on with LLMs/AI; strong SQL and Python; dashboards (Tableau/Power BI/Looker); clear communication; ability to structure ambiguous problems; manage multiple workstreams.
SQL, Python, Tableau, Power BI, Looker, Snowflake, BigQuery, Databricks, LLMs, Generative AI
2w
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Senior Director, Applied AI Product
Philadelphia or Boston or New York City or Baltimore or Washington, D.C. or Charlotte or Raleigh or Durham or Atlanta or Chicago
$200k-$250k/yr HybridFull Time
HealthVerity
HealthVerity: Privacy-protected healthcare data exchange and patient identity platform.
10+ YOE10+ years product management experience with senior AI/data product leadership; experience taking AI products to production, partnering with engineering and data science, strong communication and strategic skills.
3w
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Applied Scientist, AI & Deep Learning (mid to senior level)
Cambridge, Massachusetts, United States
$120k-$220k/yr HybridFull Time
Charles River Analytics
Charles River Analytics: Develops human-centered AI and intelligent systems for national security.
3+ YOEU.S. citizen able to obtain security clearance, Bachelors in CS or related field required, 3+ years building ML/AI systems (or graduate degree), Python and Linux proficiency, strong math and communication skills.
Python, Linux