82 applied scientist jobs at 39 companies in Massachusetts

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Senior Applied Scientist
North Reading, Massachusetts, United States
$167k-$226k/yr OnsiteFull Time
Amazon
AmazonNASDAQ: AMZN: Multinational technology focused on e-commerce and cloud computing.
3+ YOERequires 3+ years building machine learning models, PhD or master's degree plus 6+ years applied research, programming, deep learning, control, simulation, and real-time controller experience.
Java, C++, Python, IsaacLab, MuJoCo, Drake, R, scikit-learn, Apache Spark, MXNet, TensorFlow, NumPy, SciPy, Hadoop, MATLAB, ROS
1w
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Applied AI Scientist - Hybrid
Boston, Massachusetts, United States
$100k-$120k/yr HybridFull Time
XPO
XPONYSE: XPO: Provider of less-than-truckload (LTL) freight transportation and logistics.
1+ YOEBachelor's degree or equivalent experience, 1+ year designing model evaluation benchmarks, applied AI systems experience, Python and modern ML/AI frameworks, and strong stakeholder communication skills.
Python, PyTorch, HuggingFace, Chronos, RLHF, RAG
1d
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Applied Scientist, AI/ML
United States or Berlin or Boston or Cologne or Karlsruhe or London or Munich or San Francisco or Zurich
HybridFull Time, Part Time
QuantCo
QuantCo: Privately held data-science and AI engineering helping enterprises and public-sector organizations make decisions.
Expertise in machine learning, statistics, econometrics, or causal inference; strong mathematical and statistical foundations; Python and ML ecosystem fluency; and a quantitative degree. Advanced degree and foundation-model experience preferred.
Python, pandas, Polars, scikit-learn, PyTorch, JAX, XGBoost, LightGBM
2mo
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Staff Applied Scientist (Distribution Center)
Alabama or Arkansas or California or Colorado or Florida or Georgia or Illinois or Kentucky or Massachusetts or Michigan or Montana or Missouri or Nevada or New Jersey or New York or North Carolina or Oregon or Pennsylvania or Texas or Washington or Utah or Virginia or Wisconsin or United States
$192k-$288k/yr RemoteFull Time
Afresh
Afresh: Private AI software helping grocery retailers order, manage, and sell food with less waste.
4+ YOEMS/PhD in a quantitative field or equivalent experience; 4+ years (PhD) or 8+ years (MS) industry experience; expertise in inventory optimization, forecasting, stochastic optimization; ability to produce production-quality implementations in the Python data stack; strong communication.
Python, numpy, torch, pandas
1mo
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Applied Scientist, AI & Deep Learning (mid to senior level)
Cambridge, Massachusetts, United States
$120k-$220k/yr HybridFull Time
Charles River Analytics
Charles River Analytics: Private R&D developing human-centered AI, robotics, and autonomous systems for government and commercial customers.
3+ YOEU.S. citizen able to obtain security clearance, Bachelors in CS or related field required, 3+ years building ML/AI systems (or graduate degree), Python and Linux proficiency, strong math and communication skills.
Python, Linux
2w
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Senior Applied Research Scientist – GPU Native Numerical Algorithms
California or New York or Massachusetts or Pennsylvania
$192k-$357k/yr RemoteFull Time
NVIDIA
NVIDIANASDAQ: NVDA: Computing platform for AI and accelerated graphics.
5+ YOEPhD or equivalent experience, 5+ years in computational science, numerical methods, or HPC, and experience with C++, Python, CUDA/GPU code, numerical software, and GPU performance analysis.
C++, Python, CUDA, GPU, MPI, NCCL, PETSc, Trilinos, MFEM, libCEED, OpenFOAM, NVIDIA Warp, CUDA-X, cuSPARSE, cuSOLVER, Ansys, Abaqus, LS-DYNA, Siemens Simcenter, Dassault SIMULIA, Altair, Cadence, Synopsys, COMSOL, MathWorks, SC, SIAM CSE, SIAM SISC, CMAME, IJNME, JCP, AIAA, USNCCM, WCCM
2w
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Senior Applied Research Scientist – GPU Native Numerical Algorithms
California or New York or Pennsylvania or Massachusetts
$192k-$357k/yr RemoteFull Time
NVIDIA
NVIDIANASDAQ: NVDA: Computing platform for AI and accelerated graphics.
5+ YOEPhD or equivalent experience and 5+ years in computational science, numerical methods, or HPC; requires C++/Python, CUDA or GPU code, PDE methods, solver development, and GPU performance analysis.
C++, Python, CUDA, GPU, CUDA-X, Warp, PETSc, Trilinos, MFEM, libCEED, OpenFOAM, cuSPARSE, cuSOLVER, Ansys, Abaqus, LS-DYNA, Siemens Simcenter, Dassault SIMULIA, Altair, Cadence, Synopsys, COMSOL, MathWorks, MPI, NCCL
2w
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Senior Applied Research Scientist – GPU Native Numerical Algorithms
California or New York or Massachusetts or Pennsylvania
$192k-$357k/yr RemoteFull Time
NVIDIA
NVIDIANASDAQ: NVDA: Computing platform for AI and accelerated graphics.
5+ YOEPhD or equivalent in a technical field, 5+ years of relevant experience, numerical software development in C++ and Python, CUDA/GPU optimization, and expertise in numerical methods and high-performance computing.
C++, Python, CUDA, CUDA-X, Warp, PETSc, Trilinos, MFEM, libCEED, OpenFOAM, NVIDIA Warp, cuSPARSE, cuSOLVER, Ansys, Abaqus, LS-DYNA, Siemens Simcenter, Dassault SIMULIA, Altair, Cadence, Synopsys, COMSOL, MathWorks, MPI, NCCL
1w
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Sr. Scientist I/Sr. Scientist II, Applied AI & Agentic Systems for Drug Discovery
Boston or San Francisco
$160k-$220k/yr HybridFull Time
Antares Therapeutics
Antares Therapeutics: Private biotechnology developing first-in-class precision medicines for cancer and other serious diseases.
5+ YOEPhD or equivalent in a quantitative field, 5+ years relevant experience for Scientist I or 8+ for Scientist II, drug discovery contributions, LLM agent development, Python, MLOps, and scientific communication.
Large Language Models (LLM), Model Context Protocol (MCP), LIMS, ELN, MLOps, Python, Claude, GPT, Claude Code, Codex, RDKit, OpenEye, Schrödinger
2mo
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Quantum Scientist - Applied QEC
Boston, Massachusetts, United States
$135k-$170k/yr HybridFull Time
Riverlane
Riverlane: Quantum computing building real-time error-correction software and hardware for computer makers, governments, and research labs.
PhD required with research experience in quantum computing; experience designing/running/analyzing experiments or simulations; strong written/verbal communication; customer collaboration; willingness to travel US/UK.
DeltaKit Software, Deltaflow
1mo
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Applied Hypersonics Research Principal Scientist/Engineer
Andover, Massachusetts, United States
$118k-$140k/yr OnsiteFull Time
Protection Strategies Inc.
Protection Strategies Inc.: Employee-owned contract R&D serving government and commercial customers across defense, healthcare, energy, and industrial markets.
Advanced degree or equivalent experience in chemistry, physics, or applied engineering; extensive experimental and data analysis experience; technical leadership; peer-reviewed publications; excellent written and oral English; U.S. citizenship.
Schlieren, Pitot, PLIF, IR, UV, laser absorption, emission spectroscopy, vacuum systems, plasma technologies
2mo
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AI Research Scientist, Applied AI
Alabama or Arizona or California or Colorado or District of Columbia or Florida or Georgia or Hawaii or Illinois or Indiana or Kansas or Massachusetts or Maryland or Michigan or Minnesota or Missouri or Montana or North Carolina or New Jersey or New Mexico or Nevada or New York or Ohio or Oklahoma or Oregon or Rhode Island or Tennessee or Texas or Utah or Virginia or Washington or Wisconsin or West Virginia or United Kingdom
$120k-$170k/yr RemoteFull Time
Slingshot Aerospace
Slingshot Aerospace: Private aerospace software helping government and commercial operators track, model, and coordinate space activity.
2+ YOEActive U.S. security clearance (Secret minimum), Masters (or PhD) in related field, 2+ years' relevant experience (or PhD research), AI/ML expertise, software development skills, strong communication, ability to work with multidisciplinary teams.
Python, R, C++, Java, Github, CI/CD
3d
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Senior Principal Scientist, Applied AI & Agentic Systems for Small-Molecule Drug Discovery
Boston, Massachusetts, United States
$168k-$252k/yr HybridFull Time
Vertex Pharmaceuticals
Vertex PharmaceuticalsNASDAQ: VRTX: Global biotechnology investing in scientific innovation.
8+ YOEPh.D. in a relevant scientific discipline and 8+ years applying computational chemistry, cheminformatics, or related approaches to small-molecule drug discovery; expertise in AI-enabled research and cross-functional leadership required.
AI, agentic systems, large language models, retrieval-augmented workflows, computational chemistry, cheminformatics, machine learning, scientific data science
1mo
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Senior Research Data Scientist
Boston or New York
$330k-$375k/yr HybridFull Time
Roku
RokuNASDAQ: ROKU: TV streaming platform powering the global television ecosystem.
10+ YOEPhD-preferred research data scientist with 10+ years applying causal inference and ML to large observational datasets; expertise in observational causal methods, communication skills, and productionizing pipelines.
Spark, Ray, SQL, Python, scikit-learn, XGBoost, LightGBM
1mo
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Data Scientist
Boston, Massachusetts, United States
$116k-$142k/yr OnsiteFull Time
Blue Cross Blue Shield of Massachusetts
Blue Cross Blue Shield of Massachusetts: A tax-paying nonprofit Massachusetts health insurance plan serving individuals, families, businesses, and three million members.
5+ YOEBachelor's in quantitative field required, 5+ years applied analytics experience, proficiency in SAS/R/Python, experience with health plan quality and Medicare Star ratings preferred, strong communication and statistical skills.
SAS, R, Python
2w
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Staff Data Scientist
Westwood, Massachusetts, United States
$170k-$220k/yr HybridFull Time
The Predictive Index
The Predictive Index: Private HR technology providing behavioral assessments, talent optimization software, workshops, and consulting to employers.
7+ YOERequires 7+ years of staff-level product data science experience, product analytics and experimentation expertise, infrastructure-building experience, and a graduate degree or equivalent applied experience in a quantitative field.
AI
1mo
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QSP postdoctoral scientist
Boston or Indianapolis
$58k-$123k/yr OnsiteFull Time
Eli Lilly and Company
Eli Lilly and CompanyNYSE: LLY: Uniting caring with discovery to make life better.
PhD in quantitative pharmacology/systems biology/applied math or related, experience with QSP/ODE models, virtual populations, parameter estimation; proficiency in R, Matlab/Simbiology, Python, NONMEM or Monolix; authorized to work in the US.
R, Matlab/Simbiology, Python, NONMEM, Monolix
1mo
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Senior Bioinformatics Scientist
Boston, Massachusetts, United States
OnsiteFull Time
Cellular Intelligence
Cellular Intelligence: AI-native clinical-stage TechBio building cell-signaling foundation models and developing regenerative cell therapies.
3+ YOEPhD or equivalent experience preferred,3+ years developing bioinformatics methods and pipelines for single-cell/spatial transcriptomics; strong Python and/or R skills; experience with Nextflow or Snakemake, containers, version control, and applying LLMs; mentorship experience.
Python, R, Nextflow, Snakemake, LLMs
2mo
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Applications Scientist 3
Hillsboro or Wilmington or Texas or United States
$97k-$145k/yr OnsiteFull Time
Onto Innovation
Onto InnovationNYSE: ONTO: Semiconductor metrology and inspection equipment manufacturer.
0+ YOEDegree in physics, materials science, EE, applied math or related; 0-3 years experience; optics and metrology knowledge; scripting (Matlab/Python) and data analysis a plus; able to travel up to 20% and work in fabs up to 40%.
Matlab, Python
1mo
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AI Research Scientist
Bethesda or Cambridge
OnsiteFull Time
Netrias
Netrias: Private U.S. AI software that harmonizes life-sciences data for biopharma and research customers.
Experience developing AI models, identifying and fixing model failures, and applying curiosity to advance machine learning state of the art.