18 associate principal scientist jobs at 9 companies in Danvers, MA

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Associate Principal Scientist, Biologics AI
Cambridge or Waltham or Gaithersburg
$145k-$217k/yr OnsiteFull Time
AstraZeneca
AstraZenecaLondon Stock Exchange: AZN: Researches and develops medicines to treat major diseases globally.
8+ YOEPhD plus typically 8+ years or master's plus 12+ years in a quantitative field; advanced ML expertise applied to proteins or biologics, full ML lifecycle leadership, cloud environments, and cross-functional scientific leadership.
PyTorch, TensorFlow
2d
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Associate Principal Scientist, Clinical Research
Rahway or South San Francisco or Boston or West Point
$142k-$224k/yr HybridFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Develops and manufactures prescription medicines, vaccines, and animal health products.
3+ YOELife sciences degree plus 3–11+ years related experience depending on degree; extensive Phase 1 or Phase 2–3 trial experience, vaccine programs, project management, scientific writing, GCP, ICH, and regulatory expertise.
Good Clinical Practice (GCP), ICH guidelines, SOPs, WMA, CTD
2d
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Associate Principal Scientist, Clinical Research
Rahway or Boston or West Point or South San Francisco
$142k-$224k/yr HybridFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Produces prescription medicines, vaccines, and animal health products.
3+ YOELife sciences degree plus 3–11+ years related experience, including Phase 1 or Phase 2–3 clinical trials. Requires vaccine program management, GCP/ICH knowledge, scientific writing, project leadership, data evaluation, and mentoring.
3d
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Associate Principal Scientist, In Vivo Pharmacology, Oncology
Boston or South San Francisco or Rahway or United States or Puerto Rico
$145k-$228k/yr OnsiteFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Develops and manufactures prescription medicines, vaccines, and animal health products.
5+ YOEPhD with 5+ years, MS with 7+ years, or BS with 10+ years in a related STEM field; oncology in vivo pharmacology, preclinical models, CRO management, and supervisory experience required.
Immunoassays, Immunohistochemistry (IHC), Mass Spectrometry Imaging, Multiplex Assays
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Associate Principal Scientist, In Vivo Pharmacology, Oncology
Boston or South San Francisco or United States or Puerto Rico or Rahway or California or Los Angeles
$145k-$228k/yr OnsiteFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Produces prescription medicines, vaccines, and animal health products.
5+ YOEPhD plus 5+ years, MS plus 7+ years, or BS plus 10+ years in a related STEM field and oncology drug discovery; requires in vivo oncology pharmacology, CRO study management, and supervisory experience.
Immunoassays, Immunohistochemistry (IHC), In Vivo Models, In Vivo Studies, Mass Spectrometry Imaging, Mouse Models, Multiplex Assays
3d
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Associate Principal Scientist, Health Economic and Decision Sciences
West Point or Boston or United Kingdom or Zurich or Rahway
$157k-$247k/yr HybridFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Produces prescription medicines, vaccines, and animal health products.
PhD preferred or master's degree in a quantitative field, plus relevant HEOR experience, oncology economic evaluation expertise, health economic modeling, HTA submissions, publications, and strong collaboration skills.
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Associate Principal Scientist, Health Economic and Decision Sciences
West Point or Zurich or United Kingdom or Boston or Rahway
$157k-$247k/yr HybridFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Develops and manufactures prescription medicines, vaccines, and animal health products.
PhD preferred or master's in a quantitative health field, with relevant HEOR experience, oncology economic evaluation expertise, health economic modeling experience, HTA submissions, publications, and strong communication skills.
Health Technology Assessment (HTA)
1mo
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Principal Scientist II - Pharmacology
Cambridge, Massachusetts, United States
$126k-$234k/yr OnsiteFull Time
Novartis
NovartisSIX Swiss Exchange, NYSE: NOVN, NVS: A global pharmaceutical research and development organization focused on discovering and developing new medicines.
5+ YOEPhD with 5+ years postdoc or industry research experience, expertise in ADCs and CDX/PDX/syngeneic tumor models, cell culture, PCR, ELISA, western blot, flow cytometry; experience managing associate scientists and presenting data.
Microsoft PowerPoint, Prism, Microsoft Excel
2d
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Principal Scientist/Associate Director, DMPK
Watertown or Massachusetts
$186k-$228k/yr HybridFull Time
Disc Medicine
Disc MedicineNASDAQ: IRON: Develops treatments for patients with serious hematologic diseases.
5+ YOEMS with 8+ years of relevant experience or PhD with 5+ years of industry experience; expertise in large-molecule PK/PKPD, ADME, study design, human PK prediction, regulatory support, and cross-functional leadership.
2w
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Associate Principal Scientist, Biologics AI
Cambridge or Waltham or Gaithersburg
$145k-$217k/yr OnsiteFull Time
AstraZeneca
AstraZenecaLondon Stock Exchange: AZN: Global biopharmaceutical developing and manufacturing prescription medicines.
8+ YOEPhD plus 8+ years or master's plus 12+ years in a quantitative field; extensive biologics AI/ML expertise, protein modeling, experimental integration, ML lifecycle leadership, and cross-functional scientific leadership.
PyTorch, TensorFlow
2w
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Associate Principal Scientist, Biologics AI
Cambridge or Waltham or Gaithersburg
$145k-$217k/yr OnsiteFull Time
AstraZeneca
AstraZenecaLondon Stock Exchange: AZN: Researches, develops, and manufactures prescription medicines for major diseases.
8+ YOEPhD with 8+ years or master's with 12+ years; demonstrated biologics AI impact, advanced ML expertise, closed-loop wet-lab integration, production ML lifecycle leadership, and cross-functional leadership.
PyTorch, TensorFlow
2mo
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Principal Associate Scientist, Target Validation
Cambridge, Massachusetts, United States
$96k-$143k/yr OnsiteFull Time
Alnylam Pharmaceuticals
Alnylam PharmaceuticalsNASDAQ: ALNY: Develops RNAi therapeutics to treat rare and common diseases.
5+ YOEBS/MS in biology or related field with 5+ years industry experience; hands-on rodent in vivo dosing and tissue work; proficiency in RNA extraction, qPCR, Western blot, ELISA; mammalian cell culture; strong data analysis and communication skills.
GraphPad Prism, Microsoft Excel
2w
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Senior / Principal Associate Scientist, Advanced Cell Engineering
Boston, Massachusetts, United States
$84k-$112k/yr OnsiteFull Time
Strand Therapeutics
Strand Therapeutics: Developing programmable mRNA-based immunotherapies for cancer treatment.
2+ YOEBachelor's or master's in biological sciences, bioengineering, or a related field; 2–3+ years relevant experience and 3–5+ years in flow cytometry, cell culture, and mammalian cell experimentation.
Cytek Aurora, Excel, Microsoft PowerPoint, GraphPad Prism, FlowJo, ELN, LIMS, Hamilton liquid handlers, AssistPlus
2d
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Senior Associate Scientist/ Principal Research Associate, Antibody and Protein Engineering
Boston, Massachusetts, United States
$80k-$97k/yr OnsiteFull Time
Mediar Therapeutics
Mediar Therapeutics: Develops antibody therapies to halt and reverse organ fibrosis.
2+ YOEBachelor's or master's degree in a related life science and 2+ years of industry R&D experience; requires mammalian cell culture, recombinant protein expression, purification, characterization, data analysis, and scientific communication.
Bio-Layer Interferometry (BLI), ELISA, HPLC, FPLC, SDS-PAGE, HEK293, CHO, electronic laboratory notebook, FACS, AKTA-FPLC
2mo
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Principal Associate, Data Scientist - Card Intelligence
McLean or New York City or Cambridge
$162k-$201k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: Provides credit card, banking, and auto loan services.
5+ YOEBachelor's plus 5 years, master's/MBA plus 3 years, or PhD in a quantitative field and data analytics experience; preferred expertise in Python, machine learning, SQL, AWS, and STEM education.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL
2w
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Principal Associate, Data Scientist - Card Intelligence
McLean or New York City or Cambridge
$162k-$201k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: A diversified financial services providing banking and credit products.
5+ YOEBachelor's degree plus 5 years, master's or quantitative MBA plus 3 years, or PhD in a quantitative field; data analytics, machine learning, Python, SQL, and cloud experience required or preferred.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL
2mo
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Principal Associate Scientist, Target Validation (Cambridge, MA, US, 02142)
Cambridge, Massachusetts, United States
$96k-$143k/yr OnsiteFull Time
Alnylam
AlnylamNasdaq: ALNY: Developing and commercializing RNA interference (RNAi) therapeutics for diseases.
5+ YOEBS/MS in biology or related field with 5+ years industry experience; hands-on in vivo rodent studies, molecular assays (qPCR, Western blot, ELISA), mammalian cell culture, RNA extraction; proficiency with GraphPad Prism and Excel; strong communication and documentation skills.
GraphPad Prism, Microsoft Excel
1mo
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Principal Scientist / Associate Director, Agentic AI Research for Materials Science
Cambridge or San Francisco
$288k-$420k/yr OnsiteFull Time
Lila Sciences
Lila Sciences: Develops an AI platform for autonomous scientific research and discovery.
5+ YOEPhD with 5+ years post-PhD research and applied ML experience; track record building agentic systems; expertise in LLMs, reasoning, multimodal data, materials science grounding; Python proficiency; leadership and communication skills.
Python, LLMs, HPC

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