15 associate principal scientist jobs at 8 companies in Framingham, MA
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Associate Principal Scientist, Biologics AI
Cambridge or Waltham or Gaithersburg
$145k-$217k/yr OnsiteFull Time
8+ YOEPhD plus typically 8+ years or master's plus 12+ years in a quantitative field; advanced ML expertise applied to proteins or biologics, full ML lifecycle leadership, cloud environments, and cross-functional scientific leadership.
PyTorch, TensorFlow
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Associate Principal Scientist, 3D Translational Stem Cell Models, Immunology
Cambridge, Massachusetts, United States
$145k-$228k/yr OnsiteFull Time
4+ YOEPhD in a relevant life science or engineering field and 4+ years of industry or applied academic experience; expertise in stem cell biology, 3D models, human biospecimens, iPSC culture, gene editing, and assay development.
CRISPR, flow cytometry
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Associate Principal Scientist, 3D Translational Stem Cell Models, Immunology
Cambridge, Massachusetts, United States
$145k-$228k/yr OnsiteFull Time
4+ YOEPhD in a related STEM field and 4+ years of industry or applied academic experience; expertise in stem cell biology, 3D models, human biospecimens, iPSC systems, assay development, and scientific collaboration.
bulk transcriptomics, single-cell transcriptomics, flow cytometry, cytokine assays, multi-omics, CRISPR, spatial transcriptomics, iPSC culture, gene editing, organoid culture, Microsoft Excel
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Principal Scientist II - Pharmacology
Cambridge, Massachusetts, United States
$126k-$234k/yr OnsiteFull Time
5+ YOEPhD with 5+ years postdoc or industry research experience, expertise in ADCs and CDX/PDX/syngeneic tumor models, cell culture, PCR, ELISA, western blot, flow cytometry; experience managing associate scientists and presenting data.
Microsoft PowerPoint, Prism, Microsoft Excel
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Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory
Cambridge, Massachusetts, United States
$153k-$283k/yr HybridFull Time
PhD/MD or equivalent; extensive biomarker assay development experience across cellular, circulating, proteomic, genetic and genomic approaches; assay design/qualification for preclinical and clinical studies; leadership and external partner management.
polymerase chain reaction, next-generation sequencing, immunoassays, mass spectrometry
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Associate Principal Scientist, Biologics AI
Cambridge or Waltham or Gaithersburg
$145k-$217k/yr OnsiteFull Time
8+ YOEPhD plus 8+ years or master's plus 12+ years in a quantitative field; extensive biologics AI/ML expertise, protein modeling, experimental integration, ML lifecycle leadership, and cross-functional scientific leadership.
PyTorch, TensorFlow
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Associate Principal Scientist, Biologics AI
Cambridge or Waltham or Gaithersburg
$145k-$217k/yr OnsiteFull Time
8+ YOEPhD with 8+ years or master's with 12+ years; demonstrated biologics AI impact, advanced ML expertise, closed-loop wet-lab integration, production ML lifecycle leadership, and cross-functional leadership.
PyTorch, TensorFlow
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Principal Associate Scientist, Target Validation
Cambridge, Massachusetts, United States
$96k-$143k/yr OnsiteFull Time
5+ YOEBS/MS in biology or related field with 5+ years industry experience; hands-on rodent in vivo dosing and tissue work; proficiency in RNA extraction, qPCR, Western blot, ELISA; mammalian cell culture; strong data analysis and communication skills.
GraphPad Prism, Microsoft Excel
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Associate Scientist/Principal Associate Scientist - Oligonucleotide Chemistry
Waltham, Massachusetts, United States
$80k-$110k/yr OnsiteFull Time
4+ YOEBS in Chemistry (6+ years) or MS (4+ years) in related discipline; extensive hands-on oligonucleotide synthesis, purification, and analytical characterization experience; proficiency with automated synthesizers and HPLC/LC-MS/UV-Vis techniques; strong troubleshooting and communication skills.
Mermade, Dr. Oligo, AKTA Oligopilot, AKTA Pure, HPLC, LC-MS, UV-Vis, gel electrophoresis, SEC
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Senior / Principal Associate Scientist, Advanced Cell Engineering
Boston, Massachusetts, United States
$84k-$112k/yr OnsiteFull Time
2+ YOEBachelor's or master's in biological sciences, bioengineering, or a related field; 2–3+ years relevant experience and 3–5+ years in flow cytometry, cell culture, and mammalian cell experimentation.
Cytek Aurora, Excel, Microsoft PowerPoint, GraphPad Prism, FlowJo, ELN, LIMS, Hamilton liquid handlers, AssistPlus
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Principal Associate, Data Scientist - Card Intelligence
McLean or New York City or Cambridge
$162k-$201k/yr OnsiteFull Time
5+ YOEBachelor's degree plus 5 years, master's or quantitative MBA plus 3 years, or PhD in a quantitative field; data analytics, machine learning, Python, SQL, and cloud experience required or preferred.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL
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Principal Associate, Data Scientist - Card Intelligence
McLean or New York City or Cambridge
$162k-$201k/yr OnsiteFull Time
5+ YOEBachelor's plus 5 years, master's/MBA plus 3 years, or PhD in a quantitative field and data analytics experience; preferred expertise in Python, machine learning, SQL, AWS, and STEM education.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL
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Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory
Cambridge, Massachusetts, United States
$153k-$283k/yr HybridFull Time
PhD/MD in life sciences, extensive biomarker assay development experience, expertise in cellular/ circulating/proteomic/genomic approaches, platform experience (PCR, NGS, immunoassays, MS), team leadership and external partner management.
Polymerase Chain Reaction (PCR), Next-Generation Sequencing, Immunoassays, Mass Spectrometry
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Principal Associate Scientist, Target Validation (Cambridge, MA, US, 02142)
Cambridge, Massachusetts, United States
$96k-$143k/yr OnsiteFull Time
5+ YOEBS/MS in biology or related field with 5+ years industry experience; hands-on in vivo rodent studies, molecular assays (qPCR, Western blot, ELISA), mammalian cell culture, RNA extraction; proficiency with GraphPad Prism and Excel; strong communication and documentation skills.
GraphPad Prism, Microsoft Excel
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Principal Scientist / Associate Director, Agentic AI Research for Materials Science
Cambridge or San Francisco
$288k-$420k/yr OnsiteFull Time
5+ YOEPhD with 5+ years post-PhD research and applied ML experience; track record building agentic systems; expertise in LLMs, reasoning, multimodal data, materials science grounding; Python proficiency; leadership and communication skills.
Python, LLMs, HPC
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