22 biophysics jobs at 14 companies in San Jose, CA
2w
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Scientist II/Senior Scientist, Computational Biophysics
Cambridge or London or San Francisco
$141k-$218k/yr OnsiteFull Time
PhD or equivalent experience in computational biophysics/chemistry, deep hands-on MD and free-energy expertise, experience with OpenMM/OpenFE, ability to define and validate biophysics workflows for drug discovery.
OpenMM, OpenFE, LLM
1mo
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Senior Scientist, Drug Discovery Biochemistry & Biophysics
Redwood City, California, United States
OnsiteFull Time
3+ YOEPhD in a relevant field, 3+ years industry experience in small-molecule drug discovery, hands-on recombinant protein expression/purification, and development of biochemical, biophysical, and cellular assays with rigorous quantitative data generation.
SEC, SDS-PAGE, LC-MS, DLS, thermal shift, FR, TR-FRET, AlphaScreen, AlphaLISA, DSF, enzymatic, SPR, BLI, high content cell imaging, qPCR, NMR, X-ray crystallography, cryo-EM
6h
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Senior Scientist II, Biophysics and Protein Sciences
Redwood City, California, United States
$170k-$212k/yr HybridFull Time
8+ YOEPh.D. in biophysics, biochemistry, structural biology, or related field plus 8+ years of industry drug discovery experience; expertise in protein biochemistry, quantitative biophysics, and orthogonal assay development.
DSF, SEC-MALS, DLS, CD, ITC, SPR, BLI, SAXS, HDX-MS, NMR
2w
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Senior Scientist, Antibody Developability/Biophysics & Portfolio Support, AI for Drug Discovery (AIDD)
South San Francisco, California, United States
$168k-$312k/yr OnsiteFull Time
5+ YOEPhD or equivalent advanced experience in computational biology, biophysics, chemistry, or related fields; 5–8 years in ML, computational methods, or biophysics; expertise in antibody developability and biophysical modeling.
Python, PyTorch, TensorFlow, JAX
1mo
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Scientist - Computational Biophysics
Emeryville, California, United States
$100k-$180k/yr OnsiteFull Time
PhD in bioinformatics/computational biology/ML, strong protein structure knowledge, experience building large bioinformatic pipelines and managing high-dimensional datasets, proficiency fine-tuning ML models and integrating PLM/LLM/experimental data.
PLM, LLM, ESM, AlphaFold, Transformer
3w
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Assistant Professor - Biochemistry, Biophysics and Structural Biology - Molecular and Cell Biology
Berkeley, California, United States
$84k-$133k/yr OnsiteFull Time
PhD or MD required; demonstrated excellence and productivity in research, potential for external funding, and ability to teach and mentor undergraduate and graduate students.
3w
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Scientist/Sr Scientist – Protein Production and Purification
Palo Alto, California, United States
OnsiteFull Time
3+ YOEExpertise in recombinant protein expression and purification (mammalian and bacterial), chromatographic purification, biochemical/biophysical characterization, and independent experimental design and troubleshooting.
HEK293, CHO, ÄKTA FPLC, KingFisher, SDS-PAGE, SEC, DLS, UV-Vis spectroscopy, mass photometry, Isoelectric focusing (IEF)
3w
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Writer Editor
San Francisco, California, United States
$91k-$194k/yr OnsiteFull Time
5+ YOEBachelor's in biology/biochemistry/biophysics or equivalent,5+ years writing/editing for academia,expert editorial skills,scientific acumen,project management,and confidentiality.
4d
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Postdoctoral Fellow – Materials Engineering & Advanced Microfabrication - Next-Gen Sequencing and Diagnostics Systems, Research & Early Development
Santa Clara, California, United States
$100k-$106k/yr OnsiteFull Time
Ph.D. in a relevant engineering, physics, biophysics, or nanotechnology field; advanced microfabrication, fluidic systems, biochemical workflows, and Python instrument-control experience required.
Python, qPCR, dPCR, Bioanalyzer, TapeStation, Qubit, NanoDrop
3w
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Research Specialist / Scientist, Assay Development
Redwood City, California, United States
$130k-$166k/yr OnsiteFull Time
PhD or BSc/MSc with extensive industry assay development experience; proficiency in biochemical/biophysical assays, tissue processing, ELN documentation, HTS, and cross-functional collaboration.
ELISAs, MSD, AlphaLISA, Western Blots, qPCR, ddPCR, HTS, microscopy, high content imaging, flow cytometry, immunoprecipitation, ELN
3w
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Senior Director, Discovery Sciences & Technologies
Foster City, California, United States
$261k-$338k/yr OnsiteFull Time
15+ YOEPhD in biochemistry/related field,15+ years drug discovery experience,expertise in biochemical/biophysical/cellular assays,protein–ligand interactions,leadership and cross‑functional collaboration.
mass spectrometry
3w
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Senior Director, Discovery Sciences & Technologies
Foster City, California, United States
$261k-$338k/yr OnsiteFull Time
15+ YOEPhD in related discipline, 15+ years drug discovery experience, expertise in biochemical/biophysical/cellular assays, protein–ligand interactions, leadership and cross‑functional collaboration skills.
mass spectrometry, HTS, high‑throughput screening, automation, data analytics
1mo
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Senior Scientist, Formulation and DP Development
South San Francisco, California, United States
$155k-$168k/yr OnsiteFull Time
7+ YOEPhD (7+ yrs) or BS/MS (12+ yrs) in a scientific discipline; experience in formulation, biophysical characterization, analytical methods, stability and cGMP; strong communication and independent research skills.
HPLC, UPLC, column chromatography, UV-vis, Capillary electrophoresis, MALS, DLS, DSC, CD, FTIR, AUC, Fluorescence spectroscopy, cGMP
2mo
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Principal Scientist, Purification Process Development
South San Francisco, California, United States
$159k-$207k/yr OnsiteFull Time
10+ YOEPhD in biology/biochemistry/chemical engineering or related, 10+ years of experience; purification process characterization and validation; PPQ; CMOs; analytical methods (ELISA, HPLC, UV, SDS-PAGE) and biophysical techniques.
AKTA, HPLC, LC/MS, SDS-PAGE, DLS
2mo
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Scientist II, Developability
San Mateo, California, United States
$145k-$165k/yr OnsiteFull Time
3+ YOEPhD in biochemistry (preferred) with 3+ years industry experience or equivalent bench experience; strong expertise in biophysical/analytical antibody characterization (SEC, HIC, CE-SDS, DLS, DSF, ELISA, LC-MS); protein structure and antibody engineering experience; data analysis skills.
Milliner Platform, SEC, HIC, CE-SDS, DLS, DSF, ELISA, LC-MS, LIMS
2w
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Scientist, Biophysical Characterization (SPR/BLI)
San Francisco, California, United States
OnsiteFull Time
2+ YOEPhD (2+ years) or BS/MS (6+ years) industry experience; deep hands-on SPR/BLI assay development, kinetics analysis, ELN documentation, assay validation, and collaboration with robotics/software teams.
Carterra LSA, Gator BLI, nanoDSF, DSC, HPLC-SEC, DLS, AC-SINS, Mosquito, Tempest, I.DOT, ELN, Python, R
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