50 biophysics jobs at 30 companies in California
2w
Save
Mark Applied
Hide
Scientist II/Senior Scientist, Computational Biophysics
Cambridge or London or San Francisco
$141k-$218k/yr OnsiteFull Time
PhD or equivalent experience in computational biophysics/chemistry, deep hands-on MD and free-energy expertise, experience with OpenMM/OpenFE, ability to define and validate biophysics workflows for drug discovery.
OpenMM, OpenFE, LLM
1mo
Save
Mark Applied
Hide
Senior Scientist, Drug Discovery Biochemistry & Biophysics
Redwood City, California, United States
OnsiteFull Time
3+ YOEPhD in a relevant field, 3+ years industry experience in small-molecule drug discovery, hands-on recombinant protein expression/purification, and development of biochemical, biophysical, and cellular assays with rigorous quantitative data generation.
SEC, SDS-PAGE, LC-MS, DLS, thermal shift, FR, TR-FRET, AlphaScreen, AlphaLISA, DSF, enzymatic, SPR, BLI, high content cell imaging, qPCR, NMR, X-ray crystallography, cryo-EM
6d
Save
Mark Applied
Hide
Senior Scientist – Biophysics
San Diego, California, United States
$98k-$148k/yr OnsiteFull Time
0+ YOEPhD in a related field and 0–5 years post-PhD experience with DNA biophysics, processing enzymes, or sequencing method development; requires data interpretation, troubleshooting, communication, and collaboration.
DNA, single-molecule biophysics, data collection systems, custom instrumentation, programming, scripts, generative artificial intelligence (AI)
11h
Save
Mark Applied
Hide
Senior Scientist II, Biophysics and Protein Sciences
Redwood City, California, United States
$170k-$212k/yr HybridFull Time
8+ YOEPh.D. in biophysics, biochemistry, structural biology, or related field plus 8+ years of industry drug discovery experience; expertise in protein biochemistry, quantitative biophysics, and orthogonal assay development.
DSF, SEC-MALS, DLS, CD, ITC, SPR, BLI, SAXS, HDX-MS, NMR
2w
Save
Mark Applied
Hide
Senior Scientist, Antibody Developability/Biophysics & Portfolio Support, AI for Drug Discovery (AIDD)
South San Francisco, California, United States
$168k-$312k/yr OnsiteFull Time
5+ YOEPhD or equivalent advanced experience in computational biology, biophysics, chemistry, or related fields; 5–8 years in ML, computational methods, or biophysics; expertise in antibody developability and biophysical modeling.
Python, PyTorch, TensorFlow, JAX
1mo
Save
Mark Applied
Hide
Scientist - Computational Biophysics
Emeryville, California, United States
$100k-$180k/yr OnsiteFull Time
PhD in bioinformatics/computational biology/ML, strong protein structure knowledge, experience building large bioinformatic pipelines and managing high-dimensional datasets, proficiency fine-tuning ML models and integrating PLM/LLM/experimental data.
PLM, LLM, ESM, AlphaFold, Transformer
3mo
Save
Mark Applied
Hide
Lecturer, Physics and Biophysics
San Diego, California, United States
OnsitePart Time, Temporary
MS in Physics required; PhD and college teaching experience preferred.
1mo
Save
Mark Applied
Hide
Postdoctoral Scholar in Computational Biophysics
Merced, California, United States
$71k-$86k/yr OnsiteFull Time
PhD in a related field, experience with Linux, programming (Python/Perl/C/Fortran), molecular dynamics software (CHARMM/OpenMM/NAMD/GROMACS), and a record of peer-reviewed publications.
Linux, Python, Perl, C, Fortran, CHARMM, OpenMM, NAMD, GROMACS
6d
Save
Mark Applied
Hide
Scientist 2, Separations and Biophysics Assays
Novato, California, United States
$118k-$163k/yr OnsiteFull Time
4+ YOEPhD in chemistry, biochemistry, pharmaceutical chemistry, or related field plus 4 years' post-graduate experience, or master's degree plus 8 years. Requires glycan analysis, LC-MS, chromatography, regulatory, and communication expertise.
LC-MS, HILIC, CE, cIEF, icIEF, SEC, IEX, RP, HILIC-FLD/MS, UV, CAD, ELSD, FLD, CE-SDS, FDA, EMA, PMDA, USP, ICH
2w
Save
Mark Applied
Hide
Scientist 2, Separations and Biophysics Assays
Novato, California, United States
OnsiteFull Time
4+ YOEPhD plus 4+ years or master's plus 8+ years in chemistry, biochemistry, pharmaceutical chemistry, or related field; expertise in glycan analysis, LC-MS, chromatography, and analytical method development.
LC-MS, HILIC, CE, cIEF, icIEF, SEC, IEX, RP, UV, CAD, ELSD, FLD, MS, CE-SDS, USP, ICH, FDA, EMA, PMDA, INDs, BLAs, MAAs
3w
Save
Mark Applied
Hide
Scientist/Sr Scientist – Protein Production and Purification
Palo Alto, California, United States
OnsiteFull Time
3+ YOEExpertise in recombinant protein expression and purification (mammalian and bacterial), chromatographic purification, biochemical/biophysical characterization, and independent experimental design and troubleshooting.
HEK293, CHO, ÄKTA FPLC, KingFisher, SDS-PAGE, SEC, DLS, UV-Vis spectroscopy, mass photometry, Isoelectric focusing (IEF)
2mo
Save
Mark Applied
Hide
Protein Engineer - Biosensing
Pasadena, California, United States
$90k-$165k/yr OnsiteFull Time
Convergent Research: Incubates and operates non-profit Focused Research Organizations to solve scientific bottlenecks.
Protein design, biosensor development, and project leadership; strong biology/biophysics background; advanced degree or equivalent experience; strong communication.
protein design, lab instrumentation, scripting
3w
Save
Mark Applied
Hide
Writer Editor
San Francisco, California, United States
$91k-$194k/yr OnsiteFull Time
5+ YOEBachelor's in biology/biochemistry/biophysics or equivalent,5+ years writing/editing for academia,expert editorial skills,scientific acumen,project management,and confidentiality.
1d
Save
Mark Applied
Hide
Biological Sciences: Contract Instructor-College Credit
San Diego, California, United States
$7k-$9k/mo OnsiteFull Time, Contract
Master’s in biological science, or bachelor’s in biological science plus master’s in biochemistry, biophysics, or marine science; demonstrated cultural competency and college teaching capability.
Live Scan, Microsoft PDF
1w
Save
Mark Applied
Hide
Associate Scientist
Thousand Oaks, California, United States
$90k-$122k/yr OnsiteFull Time
2+ YOEMaster’s degree, or equivalent education and scientific experience; preferred background in pharmaceutics, biotechnology, biochemistry, biophysics, or related fields with pharmaceutical or biotechnology industry experience.
HPLC, UPLC, 2-D HPLC, mass spectrometry, capillary electrophoresis, JMP, Tableau, Spotfire
4d
Save
Mark Applied
Hide
Postdoctoral Fellow – Materials Engineering & Advanced Microfabrication - Next-Gen Sequencing and Diagnostics Systems, Research & Early Development
Santa Clara, California, United States
$100k-$106k/yr OnsiteFull Time
Ph.D. in a relevant engineering, physics, biophysics, or nanotechnology field; advanced microfabrication, fluidic systems, biochemical workflows, and Python instrument-control experience required.
Python, qPCR, dPCR, Bioanalyzer, TapeStation, Qubit, NanoDrop
3mo
Save
Mark Applied
Hide
2026/2027 - Associate Faculty - Biological Sciences
Santa Rosa, California, United States
$61-$154/hr OnsitePart Time, Temporary
Master's degree in biological sciences OR Bachelor's degree in biological sciences with Master's in Biochemistry/Biophysics/Marine Science; or equivalent, plus sensitivity to diverse student backgrounds.
3w
Save
Mark Applied
Hide
Research Specialist / Scientist, Assay Development
Redwood City, California, United States
$130k-$166k/yr OnsiteFull Time
PhD or BSc/MSc with extensive industry assay development experience; proficiency in biochemical/biophysical assays, tissue processing, ELN documentation, HTS, and cross-functional collaboration.
ELISAs, MSD, AlphaLISA, Western Blots, qPCR, ddPCR, HTS, microscopy, high content imaging, flow cytometry, immunoprecipitation, ELN
2w
Save
Mark Applied
Hide
Postdoctoral Fellow - Structural Biology and Drug Discovery
Duarte, California, United States
$35-$38/hr OnsiteFull Time
Ph.D. required; experience in protein biochemistry and X-ray crystallography; familiarity with biophysical binding assays (SPR, ITC, DSF); strong analytical, communication, and collaboration skills.
SPR, ITC, DSF, X-ray crystallography
3w
Save
Mark Applied
Hide
Senior Director, Discovery Sciences & Technologies
Foster City, California, United States
$261k-$338k/yr OnsiteFull Time
15+ YOEPhD in related discipline, 15+ years drug discovery experience, expertise in biochemical/biophysical/cellular assays, protein–ligand interactions, leadership and cross‑functional collaboration skills.
mass spectrometry, HTS, high‑throughput screening, automation, data analytics
Explore Jobs
Expand Your Job Search
Top Cities in California for Biophysics
- Biophysics jobs in Los Angeles, CA
- Biophysics jobs in San Diego, CA
- Biophysics jobs in San Jose, CA
- Biophysics jobs in San Francisco, CA
- Biophysics jobs in Fresno, CA
- Biophysics jobs in Sacramento, CA
- Biophysics jobs in Long Beach, CA
- Biophysics jobs in Oakland, CA
- Biophysics jobs in Bakersfield, CA
- Biophysics jobs in Anaheim, CA
- Biophysics jobs in Santa Ana, CA
- Biophysics jobs in Riverside, CA
- Biophysics jobs in Stockton, CA
- Biophysics jobs in Chula Vista, CA
- Biophysics jobs in Irvine, CA
- Biophysics jobs in Fremont, CA
- Biophysics jobs in San Bernardino, CA
- Biophysics jobs in Fontana, CA
- Biophysics jobs in Modesto, CA
- Biophysics jobs in Oxnard, CA