2w
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Computational Chemistry Lead
Cambridge, Massachusetts, United States
$119k-$170k/yr OnsiteFull Time
5+ YOEPh.D. (or M.S.+5yrs) in computational/medicinal chemistry, experience in small-molecule drug discovery, AI-driven design, molecular modeling, CRO management, and proficiency with scientific programming and modeling software.
Schrodinger, MOE, OpenEye, Rosetta, Python, Pipeline Pilot, KNIME
3w
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Scientist, Computational Biology
Cambridge, Massachusetts, United States
$115k-$165k/yr OnsiteFull Time
2+ YOEPhD in computational biology or related field, 2+ years industry experience, strong mass-spec proteomics and multi-omics analysis, proficiency in R or Python, statistical and ML expertise, NGS experience.
R, Python, NGS, transformers, Greenhouse
3d
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Computational Biologist
Boston, Massachusetts, United States
$75k-$92k/yr HybridFull Time
1+ YOEBachelor's in STEM with 1+ year experience (or Master's with no experience), knowledge of UNIX/Linux, Python and R, familiarity with experimental design and EMR not required, strong analytical and communication skills.
UNIX/Linux, Python, R
2mo
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Computational Biologist
Worcester, Massachusetts, United States
OnsiteFull Time
1+ YOEMaster’s degree in a quantitative field; 1-3 years experience; strong R/Python; knowledge of linear/mixed models and ML; Unix/Linux HPC/cloud experience.
Docker, Singularity, Snakemake, Nextflow, R, Python
3d
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Computational Designer
Boston, Massachusetts, United States
$70k-$85k/yr OnsiteFull Time
Applying engineering and scientific principles and collaborating with multidisciplinary teams to develop resilient design solutions.
1mo
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Computational Biologist
Worcester or Massachusetts or United States
$80k-$90k/yr OnsiteFull Time
1+ YOEMaster's required (PhD preferred), 1-3 years related experience, strong proficiency in R or Python, statistical modeling, data visualization, Unix/Linux and HPC/cloud experience, familiarity with genomics and multi-omic analysis.
R, Python, Unix, Linux, HPC, Docker, Singularity, Snakemake, Nextflow
2mo
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Computational Scientist, Protein Engineering
Boston, Massachusetts, United States
$118k-$138k/yr OnsiteFull Time
4+ YOEPhD and/or 4+ years in computational biology, bioinformatics, protein engineering, or related field; strong Python, data pipelines, Unix, and antibody engineering experience; experience with MPRA/NGS data; collaboration skills.
Python, Unix, Git, NGS data analysis
1mo
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Pathology Computational Scientist
Boston, Massachusetts, United States
$94k-$137k/yr OnsiteFull Time
Mass General Brigham: Provides integrated medical care, research, and clinical training services.
Experience in microbiome bioinformatics and machine learning, advanced deep learning skills, Python and PyTorch experience preferred, Git and SLURM familiarity, ability to manage large biomedical datasets and contribute to publications/grants.
Python, PyTorch, Git, SLURM
2w
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Computational Scientist I - Scalable Services
Burlington, Massachusetts, United States
$88k-$124k/yr OnsiteFull Time
0+ YOEPhD required in computer science, mathematics, bioinformatics, physics or related; strong computational and data analysis skills; excellent communication; experience developing software; 0+ years experience.
1mo
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Computational Pathology Scientist
Providence, Rhode Island, United States
OnsiteFull Time, Temporary
2+ YOEMaster's in computer/data science or related, 2+ years related experience, 1-2 years AI-based image analysis, strong Python and ML/DL experience, HPC/cloud experience, familiarity with foundation models and privacy-compliant deployments.
Python
1mo
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Computational Biologist, Tree of Life
Boston or London
OnsiteFull Time
Master's in computational biology or related; authorized to work in the U.K.; experience with population- and comparative-genomics at population scale using tools like GATK, bcftools, vcftools, PLINK, ANGSD, scikit-allel; pipelines (Nextflow, Snakemake); Python/R, Biopython/Bioconductor/pandas, and Git; familiarity with organellar genomics.
GATK, bcftools, vcftools, PLINK, ANGSD, scikit-allel, Nextflow, Snakemake, Python, R, Biopython, Bioconductor, pandas, Git, ESM, Evo, Nucleotide Transformer, AWS, Google Cloud, Azure
1mo
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Principal Scientist, Computational Biology
Cambridge, Massachusetts, United States
$167k-$202k/yr OnsiteFull Time
5+ YOEPhD in a quantitative field with 5+ years post‑graduate experience; advanced R or Python; experience with multi‑omics, single‑cell, spatial, and perturbation datasets; machine learning/statistical methods; strong communication.
R, Python, Claude
2w
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Principal Scientist, Computational Designer (Biologics & Peptides)
Cambridge or Boston
$140k-$210k/yr OnsiteFull Time
5+ YOEPhD in computational biology/structural biology or related, expertise in protein/peptide modeling, machine-learning-guided design, leadership in cross-functional research, and ability to work with large experimental datasets.
HPC, cloud, containers, workflow orchestration, X-ray, cryo-EM, machine-learning
2mo
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Senior Scientist - Principal Scientist, Computational Chemistry
Boston, Massachusetts, United States
OnsiteFull Time
1+ YOEPhD in Computational Chemistry or related field; 1-3+ years biotech/pharma experience; strong physics-based and ML modeling; excellent communication; design-experience with medicinal chemistry; structure-based drug discovery innovation.
Schrodinger suite, OpenEye, MOE, Python, RDKit, scikit-learn, numpy, pandas, pytorch
2w
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Principal Scientist, Computational Designer (Biologics & Peptides)
Cambridge or Boston
$140k-$210k/yr OnsiteFull Time
5+ YOEPhD in a relevant discipline, expertise in protein/peptide structure modeling and ML-guided design, ability to work with large experimental datasets, experience with HPC/cloud and containers, scientific leadership and cross-functional collaboration.
HPC, cloud, containers
2mo
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Senior/Principal Scientist, Computational Biology
Boston or United States
$150k-$225k/yr OnsiteFull Time
3+ YOEPhD in Computational Biology or related field; 3+ years of genomic/transcriptomic data analysis; strong Python (scanpy/anndata) skills; quantitative expertise; biology-focused interpretation.
Python, scanpy, anndata, single-cell tooling
3w
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Principal Computational Scientist - Discovery Biology N & I (Billerica MA)
Billerica, Massachusetts, United States
$140k-$210k/yr OnsiteFull Time
4+ YOEPhD in a quantitative or life-science discipline, significant postdoctoral or industry experience (pharma/biotech), expertise in computational biology/functional genomics, human genetics and multi-omics integration, strong programming in Python and/or R, and excellent communication.
Python, R
2mo
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Principal Computational Engineer, 3D CAD & Geometric Intelligence
Waltham or North Bethesda
$200k-$230k/yr HybridFull Time
12+ YOEExtensive experience in computational geometry, CAD/CAE, and geometry kernels; expert C++/Python; CAD interoperability; AI/ML for geometry; leadership.
C++, Python, AWS, Parasolid, ACIS, NX Open, Solid Edge, Teamcenter, Designcenter, DXF, STEP, IGES, JT, Open CASCADE, pybind11
1w
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Principal Scientist/Sr. Principal Scientist, Computational Chemistry & Molecular Design
Boston, Massachusetts, United States
$185k-$240k/yr HybridFull Time
10+ YOEPhD or equivalent experience in computational chemistry or related field; 10+ years' drug discovery experience for Principal (12+ for Senior Principal); expertise in structure- and ligand-based design, molecular dynamics, free energy methods, ML-driven design; strong communication.
Schr\u0000dinger, MOE, OpenEye, Python, Claude Code, Codex
1mo
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Senior Scientist, Computational Biology - Contract
Somerville, Massachusetts, United States
$74-$80/hr OnsiteContract
5+ YOEPhD (5+ yrs) or MS (10+ yrs) or BS (12+ yrs); broad genome editing and off-target discovery knowledge; NGS data and QC; developing and troubleshooting NGS pipelines in cloud; Nextflow/Dagster; AWS, version control, and software development best practices.
Nextflow, Dagster, AWS, NGS, CI/CD, AI agents
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