200 computational research scientist jobs at 66 companies in San Jose, CA

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Beyond Moore Computational Research Scientist
Berkeley or California
$95k-$227k/yr HybridFull Time, Temporary
Lawrence Berkeley National Laboratory
Lawrence Berkeley National Laboratory: Conducts scientific research to address global challenges.
3+ YOEPhD in computing discipline, minimum 3 years postdoctoral or equivalent research experience, expertise in processor/accelerator design, SPICE/Verilog, CAD/EDA tools, C++/Python, FPGA flows, and record of publications.
Spice, Verilog, C++, Python, Perl, UNIX shell scripts, make, configure, CHISEL, PyMTL, FPGA, CAD, EDA, ASIC
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Research Scientist, Life Sciences (Computational)
San Francisco, California, United States
$300k-$320k/yr HybridFull Time
Anthropic
Anthropic: Developing safe and reliable artificial intelligence systems.
PhD or equivalent industry research experience in computational biology or related field; track record of end-to-end computational biology research; proficiency with Linux, cloud compute, and scientific programming; strong communication with biologists and ML researchers.
Claude, Linux
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Research Scientist - Computational Neuroscience
Emeryville, California, United States
$90k-$200k/yr HybridFull Time
Astera Institute
Astera Institute: Conducts fundamental research in artificial intelligence and longevity science.
Ph.D. or equivalent in a relevant field; experience programming in Python; familiarity with Jax, Pytorch, NumPy, SciPy; research experience in computational/theoretical neuroscience; data analysis, statistics, or ML experience; ability to work independently and communicate results.
Python, Jax, Pytorch, NumPy, SciPy, C++, Linux, Git, high-performance computing environments
1w
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Senior Principal Research Scientist, Computational Chemistry
South San Francisco, California, United States
$196k-$242k/yr HybridFull Time
IDEAYA Biosciences
IDEAYA BiosciencesNASDAQ: IDYA: Develops precision medicine oncology therapies for cancer patients.
9+ YOEPhD in computational chemistry or related field, 9+ years of pharmaceutical or biotechnology experience, expertise in computational drug discovery, programming, data analysis, machine learning, and drug design software.
Schrödinger, MOE, OpenEye, Machine Learning, Artificial Intelligence, Molecular Dynamics, Quantum Mechanics, Cheminformatics, Programming, Scripting, Statistics, Data Analysis
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Research Scientist, Applied Science
Palo Alto or Paris or Abu Dhabi
$175k-$270k/yr OnsiteFull Time
GenBio AI
GenBio AI: Developing AI foundation models to simulate and program biology.
PhD (or equivalent) in CS/AI/Computational Biology, proven publication record, experience translating ML research to biology, computational discovery experience, collaboration with experimental scientists, and software engineering best practices.
AlphaFold2, AlphaFold3, RosettaFold
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Computational Scientist, Lung Transplant Immunology
San Francisco, California, United States
$64k-$195k/yr OnsiteFull Time
University of California
University of California: A public research university system providing education and healthcare.
5+ YOEAdvanced computational/statistical skills for end-to-end analysis of multimodal genomic datasets; strong R and Python proficiency; experience with reproducible workflows, HPC/cloud environments, and publication record in high-dimensional modalities.
R, Bioconductor, Seurat, Python, scanpy, anndata, scikit-learn, pandas, Linux, SLURM, Git, GitHub, conda, mamba, renv, Nextflow, Snakemake, Microsoft Visual Studio, AWS, GCP, UCSF Wynton, AWS HealthOmics
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Scientist, Computational Biology
Menlo Park, California, United States
$130k-$150k/yr HybridFull Time
MyOme
MyOme: Provides clinical whole genome analysis for personalized health insights.
Ph.D. or Master's in quantitative biosciences with relevant experience; hands-on biobank and multi-omic analysis; proficiency in Python/R, version control, cloud biobank environments; strong statistical and epidemiological skills.
Python, R, Git, DNAnexus, Terra, AWS, GCP
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Senior Scientist, Computational Biology
South San Francisco or Seattle or London
$136k-$170k/yr OnsiteFull Time
Xaira Therapeutics
Xaira Therapeutics: Develops AI models for protein and antibody drug discovery.
5+ YOEPhD in a quantitative biology field, 5+ years industry/applied research, deep single-cell RNA‑seq and Perturb‑seq expertise, experience integrating large-scale datasets, production workflow development (Nextflow), Docker, AWS, Python (numpy, pandas, scanpy, scikit-learn), Unix, and GitHub.
Nextflow, Docker, AWS, Python, numpy, pandas, scanpy, scikit-learn, Unix, GitHub
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Scientist II/Senior Scientist, Computational Biophysics
Cambridge or London or San Francisco
$141k-$218k/yr OnsiteFull Time
Lila Sciences
Lila Sciences: Develops an AI platform for autonomous scientific research and discovery.
PhD or equivalent experience in computational biophysics/chemistry, deep hands-on MD and free-energy expertise, experience with OpenMM/OpenFE, ability to define and validate biophysics workflows for drug discovery.
OpenMM, OpenFE, LLM
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Scientist, Computational Biology
Palo Alto, California, United States
$135k-$187k/yr HybridFull Time
Arc Institute
Arc Institute: Conducts biomedical research to understand and treat complex human diseases.
0+ YOEPhD in relevant field, 0–4 years postdoctoral/professional research experience, hands-on single-cell/perturbational/multi-omic analysis, expertise in perturb-seq or microglia single-cell analysis, Python proficiency, reproducible workflows, strong collaboration and communication; onsite minimum 3 days/week.
Python
3d
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Research Scientist, Google Research
Mountain View, California, United States
$174k-$252k/yr OnsiteFull Time
Google
GoogleNASDAQ: GOOGL: Provides online search, advertising, cloud computing, and consumer electronics.
2+ YOEPhD in computer science or related field, 2 years leading a research agenda, core ML model development, LLM training and generative models, publications, and 2 years coding experience preferred.
LLM, Gemini, CVPR, ICCV, NeurIPS, ICML, ICLR
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Staff Computational Scientist (Electric Grid Simulations
Mountain View or United States or United Kingdom or Chile or New Zealand or Australia or Brazil
$166k-$259k/yr HybridFull Time
Alphabet
AlphabetNASDAQ: GOOGL: Holding providing internet, software, and AI services.
6+ YOEMaster's or PhD in Electrical Engineering, 6+ years in power systems or power electronics modeling and simulation, programming experience, and expertise in power systems, numerical methods, and large-scale networks.
Python, Java, C, C++, JAX, Julia, Machine Learning
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Staff Computational Scientist (Electric Grid Simulations
Mountain View or United States or United Kingdom or Chile or New Zealand or Australia or Brazil
$166k-$259k/yr HybridFull Time
X, The Moonshot Factory
X, The Moonshot FactoryNASDAQ: GOOGL: Develops early-stage technologies and experimental projects.
6+ YOEMaster's or PhD in Electrical Engineering; 6+ years in power systems or power electronics modeling and simulation; programming in Python, Java, C/C++, or similar; expertise in power systems and numerical methods.
Python, Java, C, C++, JAX, Julia, Machine Learning
5d
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Research Scientist
Presidio, California, United States
OnsiteFull Time
Arcade
Arcade: Design and buy custom physical products using generative AI.
Ph.D. in a related AI or computer science field; top-tier publications; expert Vision-Language Model knowledge, Python, PyTorch, multimodal architectures, and transformer-based computer vision.
Vision-Language Model (VLM), Qwen-VLM, PaliGemma2, Python, PyTorch, CVPR, ICCV, ECCV, NeurIPS, ICLR, ACL
2mo
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Computational Materials Scientist - Postdoctoral Researcher
Livermore, California, United States
$123k/yr OnsiteFull Time
Lawrence Livermore National Laboratory
Lawrence Livermore National Laboratory: Develops science and technology for United States national security.
PhD in materials-related field, ability to obtain DOE Q-level clearance (U.S. citizenship required), expertise in CALPHAD, ICME, uncertainty quantification, and scientific software development; experience with thermodynamic tools and strong publication record.
Thermo-Calc, Pandat, FactSage, PyCalphad, Thermochimica, OpenCalphad, High Performance Computing, Materials Acceleration Platform
3w
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Scientist/Sr. Scientist, Computational Chemistry
San Francisco, California, United States
OnsiteFull Time
General Proximity
General Proximity: Develops proximity-based medicines to treat undruggable disease proteins.
3+ YOEPhD-preferred computational chemist with 3+ years in pharma/biotech, hands-on SBDD and ligand-based design, experience with cheminformatics, AI/ML molecular design, Python and RDKit, and cross-functional collaboration.
Schrödinger, MOE, CCDC tools, ChemAxon, KNIME, Pipeline Pilot, RDKit, DataWarrior, Spotfire, AlphaFold, Python
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Research Scientist
San Jose, California, United States
OnsiteFull Time
Adobe
AdobeNASDAQ: ADBE: Provides software for digital media creation and marketing analytics
PhD in Computer Science/AI or related field; strong publication record; experience in Generative AI, diffusion models, large-scale model training; good communication and teamwork.
Python, PyTorch, TensorFlow, Machine Learning Frameworks
2w
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Research Scientist Graduate (Computational Imaging-PICO) - 2027 Start (PhD)
San Jose, California, United States
OnsiteFull Time
ByteDance
ByteDance: Developing AI-driven content platforms and mobile applications.
PhD in CS/ECE/Imaging or related, strong foundation in image processing/computational photography/ML, proficiency with PyTorch or TensorFlow and Python/MATLAB, familiarity with C/C++, and hands-on hardware experimentation skills.
PyTorch, TensorFlow, Python, MATLAB, C, C++
19h
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Research Scientist- Robotics AI
Sunnyvale or Pittsburgh or Cambridge
$165k-$185k/yr HybridFull Time
Bosch
Bosch: Global manufacturer of automotive and industrial engineering technology.
3+ YOEPh.D. in computer science, robotics, or related field, or master's degree with 2+ years' industry experience; 3+ years' AI R&D or equivalent graduate research; programming and ML framework expertise.
Python, C++, Rust, TensorFlow, PyTorch, PPO, DQN, DDPG, NeRF, CVPR, ICRA, IROS, RSS, NeurIPS, CoRL
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Computational Clinical Scientist II, Clinical Bioinformatics
Redwood City, California, United States
$132k-$166k/yr HybridFull Time
Revolution Medicines
Revolution MedicinesNASDAQ: RVMD: Developing precision oncology therapies for RAS-addicted cancers
2+ YOEM.S. or Ph.D. in bioinformatics, biology, data science, or related field; 2+ years of pharmaceutical or biotech bioinformatics experience; R or Python programming and clinical data analysis expertise.
R, Python, GATK, Salmon, OncoKB, VEP, IDE, version control systems, GDC, TCGA, clusters, containers, cloud computing