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15 hpc engineer jobs at 10 companies in Encinitas, CA

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HPC Systems Engineer (Linux / Infrastructure)
San Diego, California, United States
$116k-$209k/yr OnsiteFull Time
General Atomics
General Atomics: Designs and manufactures unmanned aircraft and nuclear technology systems.
15+ YOEBachelor's degree or equivalent experience, 15+ years systems administration experience, deep Linux stack knowledge (NFS, ZFS, BTRFS, mdadm, LVM), scripting with Python/Ansible/Bash, troubleshooting distributed systems; SLURM and parallel file system experience desirable.
Lustre, BeeGFS, WEKA, Ceph, SLURM, Ansible, Python, Bash, Docker, Podman, Apptainer, NFS, ZFS, BTRFS, mdadm, LVM
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1mo
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Senior Engineer – AI & HPC Observability
San Diego or Austin
$155k-$206k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOEBachelors in CS/CE or equivalent; 5+ years observability and distributed systems experience; 1+ year HPE OpsRamp; strong Bash and Python; experience with OpenTelemetry, Prometheus, Grafana, Datadog, ELK, ThousandEyes; cloud skills (AWS/GCP/OpenStack/Proxmox/k8s).
HPE OpsRamp, Open Telemetry, Prometheus, Grafana, Nagios, Datadog, ELK, Thousand Eyes, Bash, Python, AWS, GCP, OpenStack, Proxmox, k8s, Netbox, MaaS, Redfish
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Senior Engineer – AI & HPC Observability
Austin or San Diego
$155k-$206k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOEBachelors in CS/CE or equivalent; 5+ years building distributed systems and modern observability tooling (Open Telemetry, Prometheus, Grafana, Datadog, ELK, etc.); 1+ year HPE OpsRamp; Bash and Python; cloud (AWS/GCP/OpenStack) and k8s; on-call participation.
HPE OpsRamp, Open Telemetry, Prometheus, Grafana, Nagios, Datadog, ELK, Thousand Eyes, Bash, Python, AWS, GCP, OpenStack, Proxmox, k8s, Netbox, MaaS, Redfish
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Sr. Software Engineer
San Diego, California, United States
$121k-$153k/yr HybridFull Time
Singular Genomics
Singular Genomics: Develops benchtop genomic sequencing platforms and spatial multiomics technology.
3+ YOE3+ years software engineering experience, strong Python, familiarity with Linux/HPC, CI/CD (Jenkins, Bitbucket, Poetry), Airflow, debugging, JavaScript/TypeScript, and working with databases and web services.
Python, Linux, HPC, Jenkins, Bitbucket, Poetry, Airflow, JavaScript, TypeScript, PostgreSQL, Django, Docker
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22h
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Software Engineer
Vista, California, United States
OnsiteFull Time
Varioscale
Varioscale: Manufacturer of advanced semiconductor failure analysis and etching equipment.
Degree in computer science/engineering or physics; experience programming in C++, CMake on Windows, Qt 5; familiarity with EMR? (not present) — exclude; desirable: HPC, C++17, VTK, PostgreSQL, Doxygen, Python 3.6.
C++, CMake, Qt 5, C++17, Visualization Toolkit (VTK), PostgreSQL, Doxygen, Python 3.6
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Data Center Deployment Lead - GPU & HPC
Austin or San Diego
$145k-$165k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOE5+ years deploying high-density data center infrastructure with hands-on racking, cabling, commissioning GPU systems; experience with high-speed fabrics, Netbox, MaaS, Linux troubleshooting and basic scripting; leadership under pressure and willingness to travel 30-40%.
Netbox, MaaS, Linux
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Data Center Deployment Lead - GPU & HPC
San Diego or Austin
$145k-$165k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOE5+ years deploying high-density data center infrastructure with hands-on racking, cabling, and commissioning of GPU systems; experience with high-speed fabrics, Netbox, MaaS, Linux troubleshooting; leadership under pressure and willingness to travel 30-40%.
Netbox, MaaS, Linux
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2w
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Research Software Engineer I - Center for AI and Research Computing (AIRC)
La Jolla, California, United States
$33-$38/hr OnsiteFull Time
Salk Institute
Salk Institute: Conducts biological research to solve global health challenges.
0+ YOEEarly-career software engineer with full-stack ability in Python and another language, Git experience, Linux familiarity, demonstrated coding portfolio, and interest in scientific collaboration and HPC.
Python, Claude Code, Git, SLURM, Claude API, Docker, Kubernetes, AWS, GCP, React, Svelte, Vue, FastAPI, Django, GitHub, Linux/Unix, CI/CD
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Systems Engineer - Microsoft Windows
La Jolla, California, United States
$101k-$161k/yr OnsiteFull Time
Institute for Defense Analyses
Institute for Defense Analyses: Operates federally funded research centers for national security analysis.
6+ YOE6+ years IT experience with 4+ years systems administration (or 8+ years with HS); advanced Linux and Windows server administration; VMware, scripting (Shell/Perl/PHP/PowerShell), patching, automation, and security hardening; ability to obtain Top Secret/SCI and DOD 8570 IAT II.
Active Directory, GPO, HPC, Nessus, Perl, PHP, PowerShell, RHEL, SQL, Shell, STIGs, VMware vSphere, vCenter, Windows Server 2022, Windows 11, Microsoft Office, Microsoft SharePoint, Microsoft WSUS, Microsoft SCCM, DNS, DHCP, VLANs, Omnissa Horizon
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1w
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Computational & Data Science Research Spec. 2 or 3 - 139471
San Diego, California, United States
$88k-$182k/yr OnsiteFull Time
University of California, San Diego
University of California, San Diego: A public research university providing higher education and healthcare.
2+ YOEBachelor's in CS/Data Science required; 2+ years relevant experience (2-5 yrs typical); strong AI, systems, algorithms, and software engineering skills; Python, cloud, React, HPC experience preferred.
Python, React, cloud computing, HPC, LLM
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1mo
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Scientist, Computational Chemist & MLOps Engineer
Madison or Pasadena or San Diego or Verona
$100k-$125k/yr OnsiteFull Time
Arrowhead Pharmaceuticals
Arrowhead PharmaceuticalsNASDAQ: ARWR: Develops RNAi medicines to treat genetic and intractable diseases.
Bachelor's or Master's in a related field; strong Python, Linux, and Git skills; foundational statistics and ML knowledge; experience with biological/omics datasets, reproducible workflows, and scientific software; PhD preferred for senior levels.
Python, Linux, Git, HPC
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Product Line Product Manager – Accelerated Compute
Austin or San Diego
$150k-$195k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOE5+ years product management or field engineering experience; deep expertise with GPU/accelerated compute for AI/HPC; analytical problem-solving, cross-team leadership, and product launch experience; Bachelor's degree in CS/Engineering or related field.
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Product Line Product Manager – Accelerated Compute
San Diego or Austin
$150k-$195k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOE5+ years product management or field engineering experience, deep expertise in GPU/accelerated compute for AI/HPC, strong analytical and cross-team leadership skills, completed product launches, and a technical degree in CS/Engineering or related field.
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Machine Learning Scientist – Clinical Prediction
Boston or San Diego or United States
$148k-$186k/yr HybridFull Time
Iambic Therapeutics
Iambic Therapeutics: Develops novel medicines using an AI-driven discovery platform.
3+ YOEMS in chemistry/bio/chemical engineering or PhD/equivalent; 3+ years relevant experience; strong Python and deep-learning fine-tuning skills; clinical dataset experience; data science and engineering best practices; familiarity with Docker, CUDA, Kubernetes, and Weights & Biases.
Python, Docker, CUDA, Kubernetes, Weights & Biases, HPC
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2mo
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Advisor - Data Architect, Data Foundry
San Diego or San Francisco or Boston or Louisville or Indianapolis
$152k-$244k/yr OnsiteFull Time
Eli Lilly and Company
Eli Lilly and CompanyNYSE: LLY: Researches and manufactures medicines for human health.
2+ YOEM.S. or PhD in a STEM field with relevant data architecture/engineering or scientific informatics experience (MS+6 yrs or PhD+2 yrs). Expertise in data modeling, lakehouse and platform architecture, knowledge graphs, semantic web standards, cloud and streaming data patterns.
Databricks, Snowflake, Spark, dbt, Kafka, Kinesis, Flink, Neo4j, Amazon Neptune, TigerGraph, TileDB, MongoDB, Pinecone, Weaviate, pgvector, Delta Lake, Unity Catalog, RDF, OWL, SPARQL, Protégé, Benchling, C, C++, Rust, SQL, LIMS, ELN, HPC
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