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15 hpc engineer jobs at 11 companies in National City, CA

1mo
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Senior Engineer – AI & HPC Observability
San Diego or Austin
$155k-$206k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOEBachelors in CS/CE or equivalent; 5+ years observability and distributed systems experience; 1+ year HPE OpsRamp; strong Bash and Python; experience with OpenTelemetry, Prometheus, Grafana, Datadog, ELK, ThousandEyes; cloud skills (AWS/GCP/OpenStack/Proxmox/k8s).
HPE OpsRamp, Open Telemetry, Prometheus, Grafana, Nagios, Datadog, ELK, Thousand Eyes, Bash, Python, AWS, GCP, OpenStack, Proxmox, k8s, Netbox, MaaS, Redfish
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1mo
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Senior Engineer – AI & HPC Observability
Austin or San Diego
$155k-$206k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOEBachelors in CS/CE or equivalent; 5+ years building distributed systems and modern observability tooling (Open Telemetry, Prometheus, Grafana, Datadog, ELK, etc.); 1+ year HPE OpsRamp; Bash and Python; cloud (AWS/GCP/OpenStack) and k8s; on-call participation.
HPE OpsRamp, Open Telemetry, Prometheus, Grafana, Nagios, Datadog, ELK, Thousand Eyes, Bash, Python, AWS, GCP, OpenStack, Proxmox, k8s, Netbox, MaaS, Redfish
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4d
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AI & HPC Infrastructure Engineer
Albany or Arlington or Atlanta or Austin or Beaverton or Bentonville or Boston or Carmel or Charlotte or Chicago or Cincinnati or Cleveland or Columbus or Culver City or Denver or Des Moines or Detroit or Hartford or Houston or Irvine or Irving or Kirkland or Miami or Milwaukee or Minneapolis or Morristown or Mountain View or Nashville or New York City or Oklahoma City or Overland Park or Philadelphia or Pittsburgh or Raleigh or Redmond or Sacramento or San Diego or San Francisco or Scottsdale or Seattle or St. Louis or St. Petersburg or Walnut Creek or United States
$80k-$266k/yr HybridFull Time
Accenture
AccentureNYSE: ACN: Global professional services firm providing consulting and technology solutions.
5+ YOERequires 5+ years designing AI infrastructure, accelerated computing, clusters, orchestration, and automation; bachelor's degree or equivalent experience. Strong Kubernetes, Python, Terraform, and cloud expertise required.
Slurm, Run:ai, Kubernetes, NVIDIA Base Command Manager (BCM), NVIDIA NGC, NCCL, NVLink, CUDA, TensorRT-LLM, vLLM, SGLang, Triton Inference Server, NVIDIA Dynamo, llm-d, MLPerf, NCCL tests, fio, iperf, InfiniBand, Ethernet, SONiC, NVMe, NVMe-oF, VAST, Weka, DDN, AWS, Azure, GCP, VMware, Nutanix, Python, Terraform, Ansible, REST, OpenAPI, JSON, YAML, TensorFlow, PyTorch, JAX, Jupyter notebooks, Google Colab, MCP
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1w
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Software Engineer
San Diego, California, United States
$108k-$128k/yr HybridFull Time
Singular Genomics
Singular Genomics: Develops advanced genomic sequencing and spatial multiomics platforms.
2+ YOERequires 2–5 years of software engineering experience, strong Python, Linux and HPC familiarity, CI/CD and package tooling experience, JavaScript knowledge, and debugging skills.
Python, Jenkins, Bitbucket, Poetry, Linux, HPC, Airflow, JavaScript, TypeScript, Numpy, Scipy, RAPIDS, POLARS, PostGRES, celery, Flask, Django, Docker
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2w
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Software Engineer
Vista, California, United States
OnsiteFull Time
Varioscale
Varioscale: Manufacturer of advanced semiconductor failure analysis and etching equipment.
Degree in computer science/engineering or physics; experience programming in C++, CMake on Windows, Qt 5; familiarity with EMR? (not present) — exclude; desirable: HPC, C++17, VTK, PostgreSQL, Doxygen, Python 3.6.
C++, CMake, Qt 5, C++17, Visualization Toolkit (VTK), PostgreSQL, Doxygen, Python 3.6
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2mo
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Systems Engineer - Microsoft Windows
La Jolla, California, United States
$101k-$161k/yr OnsiteFull Time
Institute for Defense Analyses
Institute for Defense Analyses: Operates federally funded research centers for national security analysis.
6+ YOE6+ years IT experience with 4+ years systems administration (or 8+ years with HS); advanced Linux and Windows server administration; VMware, scripting (Shell/Perl/PHP/PowerShell), patching, automation, and security hardening; ability to obtain Top Secret/SCI and DOD 8570 IAT II.
Active Directory, GPO, HPC, Nessus, Perl, PHP, PowerShell, RHEL, SQL, Shell, STIGs, VMware vSphere, vCenter, Windows Server 2022, Windows 11, Microsoft Office, Microsoft SharePoint, Microsoft WSUS, Microsoft SCCM, DNS, DHCP, VLANs, Omnissa Horizon
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1w
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Senior Software Engineer - Defense Simulation
Fort Walton Beach or Sunnyvale or Washington or San Diego or Ann Arbor or London or Stuttgart or Munich or Stockholm or Bengaluru or Seoul or Tokyo
$140k-$180k/yr OnsiteFull Time
Applied Intuition
Applied Intuition: Developing software and simulation infrastructure for autonomous vehicles.
3+ YOEMaster’s degree or equivalent experience, 3+ years modern C++ development, simulation interoperability and communication protocols, Linux, Docker, Git, and eligibility for a U.S. Secret clearance.
C++, Python, DIS, HLA, DSEEP, DDS, ZeroMQ, Kafka, Redis, protobuf, AFSIM, NGTS, Docker, RHEL, Ubuntu, git, Visual Studio Code, GitLab, SonarQube, Artifactory, Azure Container Registry, OMS, UCI, HPC
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2d
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IT DevOps Applications Engineer - Hardware Engineering
San Diego, California, United States
$102k-$154k/yr OnsiteFull Time
ASML
ASMLNASDAQ: ASML: Manufactures lithography systems used to print patterns on wafers.
5+ YOEBachelor’s degree or equivalent practical experience and 5 years supporting enterprise Windows desktop, virtual desktop, or Citrix environments; experience with automated testing and CI/CD pipelines required.
Windows, Windows Virtual Desktop Infrastructure (VDI), Citrix, Linux, High Performance Computing (HPC), PowerShell, CI/CD, Ansys, Star-CCM+, HyperWorks, MATLAB, Agile, Scrum, SAFe, Computational Fluid Dynamics (CFD), Finite Element Analysis (FEA)
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4w
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Computational & Data Science Research Spec. 2 or 3 - 139471
San Diego, California, United States
$88k-$182k/yr OnsiteFull Time
University of California, San Diego
University of California, San Diego: A public research university providing higher education and healthcare.
2+ YOEBachelor's in CS/Data Science required; 2+ years relevant experience (2-5 yrs typical); strong AI, systems, algorithms, and software engineering skills; Python, cloud, React, HPC experience preferred.
Python, React, cloud computing, HPC, LLM
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1mo
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Scientist, Computational Chemist & MLOps Engineer
Madison or Pasadena or San Diego or Verona
$100k-$125k/yr OnsiteFull Time
Arrowhead Pharmaceuticals
Arrowhead PharmaceuticalsNASDAQ: ARWR: Develops RNAi medicines to treat genetic and intractable diseases.
Bachelor's or Master's in a related field; strong Python, Linux, and Git skills; foundational statistics and ML knowledge; experience with biological/omics datasets, reproducible workflows, and scientific software; PhD preferred for senior levels.
Python, Linux, Git, HPC
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Product Line Product Manager – Accelerated Compute
Austin or San Diego
$150k-$195k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOE5+ years product management or field engineering experience; deep expertise with GPU/accelerated compute for AI/HPC; analytical problem-solving, cross-team leadership, and product launch experience; Bachelor's degree in CS/Engineering or related field.
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Product Line Product Manager – Accelerated Compute
San Diego or Austin
$150k-$195k/yr OnsiteFull Time
Cirrascale
Cirrascale: Provides specialized GPU-based cloud infrastructure for AI workloads.
5+ YOE5+ years product management or field engineering experience, deep expertise in GPU/accelerated compute for AI/HPC, strong analytical and cross-team leadership skills, completed product launches, and a technical degree in CS/Engineering or related field.
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2mo
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Machine Learning Scientist – Clinical Prediction
Boston or San Diego or United States
$148k-$186k/yr HybridFull Time
Iambic Therapeutics
Iambic Therapeutics: Develops novel medicines using an AI-driven discovery platform.
3+ YOEMS in chemistry/bio/chemical engineering or PhD/equivalent; 3+ years relevant experience; strong Python and deep-learning fine-tuning skills; clinical dataset experience; data science and engineering best practices; familiarity with Docker, CUDA, Kubernetes, and Weights & Biases.
Python, Docker, CUDA, Kubernetes, Weights & Biases, HPC
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1w
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Snowflake Advanced AI Solution Lead
San Francisco or Milwaukee or Dallas or Columbus or Kirkland or Cincinnati or New York City or Cleveland or Oklahoma City or Austin or Albany or Chicago or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Mountain View or Scottsdale or Morristown or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
$80k-$294k/yr HybridFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
5+ YOERequires 5+ years in machine learning engineering or science, 5+ years in computer science foundations, 3+ years in distributed systems, 2+ years with Snowflake Cortex AI and cloud AI/ML deployment, plus a bachelor's degree or equivalent experience.
Snowflake Cortex AI, Cortex Agents, Cortex Analyst, Cortex Search, Deep Learning, Generative AI, Large Language Models, DevOps, MLOps, LLMOps, HPC, Python, TensorFlow, PyTorch, LLM, C++, Java, R, SQL
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2mo
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Advisor - Data Architect, Data Foundry
San Diego or San Francisco or Boston or Louisville or Indianapolis
$152k-$244k/yr OnsiteFull Time
Eli Lilly and Company
Eli Lilly and CompanyNYSE: LLY: Researches and manufactures medicines for human health.
2+ YOEM.S. or PhD in a STEM field with relevant data architecture/engineering or scientific informatics experience (MS+6 yrs or PhD+2 yrs). Expertise in data modeling, lakehouse and platform architecture, knowledge graphs, semantic web standards, cloud and streaming data patterns.
Databricks, Snowflake, Spark, dbt, Kafka, Kinesis, Flink, Neo4j, Amazon Neptune, TigerGraph, TileDB, MongoDB, Pinecone, Weaviate, pgvector, Delta Lake, Unity Catalog, RDF, OWL, SPARQL, Protégé, Benchling, C, C++, Rust, SQL, LIMS, ELN, HPC
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