323 information systems manager jobs at 219 companies in Los Angeles, CA

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Information Systems Manager
Los Angeles, California, United States
$105k-$150k/yr OnsiteFull Time
Gracelight Community Health
Gracelight Community Health: Provides primary and specialty healthcare services to underserved communities.
3+ YOE1+ Mgmt3-5 years IT/IS experience with network, systems, helpdesk; 1-2 years supervisory experience preferred; knowledge of network infrastructure, Active Directory, backup/DR, HIPAA-related IT controls; bachelor's preferred or equivalent certifications.
Active Directory, DNS, DHCP, routers, switches, firewalls, LAN, WAN
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Information Systems Manager
Los Angeles, California, United States
$105k-$150k/yr OnsiteFull Time
Gracelight Community Health
Gracelight Community Health: Operates community health clinics providing primary and specialty medical care.
3+ YOE1+ MgmtOversee IS operations and helpdesk; supervise staff; 3-5 years IT/IS experience with network/admin and helpdesk; 1-2 years supervisory experience preferred; AD, network, security, HIPAA familiarity; relevant certifications preferred.
Active Directory, DNS, DHCP
3w
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Information Systems Project Manager 3/4
Palmdale, California, United States
$114k-$171k/yr OnsiteFull Time
Northrop Grumman
Northrop GrummanNYSE: NOC: Designs and manufactures advanced aerospace and defense systems.
3+ YOEAbility to obtain Top Secret clearance, 3+ years project management experience, experience with MS Office, TRIO, ServiceNow, budget and schedule management, and presenting status to stakeholders.
Microsoft PowerPoint, Microsoft Excel, Microsoft SharePoint, Microsoft Project, TRIO, Service Now
3w
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Information Systems Project Manager 3/4
Palmdale, California, United States
$114k-$171k/yr OnsiteFull Time
Northrop Grumman
Northrop GrummanNYSE: NOC: Develops and manufactures advanced aerospace, defense, and space systems.
Ability to obtain US Top Secret clearance; experience leading multiple IT projects, managing cost/schedule/performance, preparing status reports, and using project management tools (MS Office, TRIO, Service Now).
Microsoft PowerPoint, Microsoft Excel, Microsoft SharePoint, Microsoft Project, TRIO, Service Now
2w
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Associate Director, Information Systems
Thousand Oaks, California, United States
$172k-$232k/yr RemoteFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
9+ YOE3+ MgmtTechnology leader with product and people management experience delivering data, analytics, AI, and cloud solutions; experience with enterprise data platforms and stakeholder partnership.
Databricks, Python, SQL, Apache Spark, AWS, Live Narrative, Spec-Driven Development (SDD)
2w
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Senior Information Systems Security Manager (ISSM)
Torrance, California, United States
$151k-$187k/yr HybridFull Time
Epirus
Epirus: Sells software-defined high-power microwave systems for counter-drone defense.
5+ YOE5+ years ISSO/ISSM experience, RMF competency, IAM Level III cert (CISSP/GSLC/CISM), active TS/SCI clearance, RMF/DAAPM experience, familiarity with SCAP/STIG/Nessus, and ability to lead ATO/IATT/ATC efforts.
RMF, DAAPM, SCAP, STIG, Nessus, Windows, Linux
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Principal Architect, Information Systems
Long Beach or United States
$106k-$230k/yr RemoteFull Time
Molina Healthcare
Molina HealthcareNYSE: MOH: Provides managed health insurance through government-sponsored benefit programs.
8+ YOE4+ MgmtBachelor's degree required; 8+ years IT infrastructure experience, 2+ years hands-on implementation, 4+ years leadership; experience with Provider Data Modeling/QNXT, Azure DataFactory, SQL on Azure, AI integration, performance testing; strong executive communication.
Azure, Azure DataFactory, SQL, QNXT
2w
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Financial Information Systems Manager
Van Nuys, California, United States
OnsiteFull Time
Capstone Green Energy
Capstone Green EnergyNASDAQ: CGRN: Develops and manufactures microturbine-based energy generation systems.
5+ YOE5+ years ERP implementation experience, strong financial accounting knowledge, Epicor experience preferred, data mapping and migration skills, project execution and cross-functional collaboration.
Epicor ERP, Epicor E10, Epicor Kinetic, NetSuite, SAP, Oracle, REST API, SSRS, Crystal Reports, Business Process Management (BPM), Business Activity Queries (BAQ)
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SR. Information Systems Network & Security Analyst
Burbank, California, United States
$37-$43/hr OnsiteFull Time
SAG-AFTRA Federal Credit Union
SAG-AFTRA Federal Credit Union: Financial services for professionals in the entertainment industry.
3+ YOEBachelor's in information security or computer science, 3+ years information security/network experience, Security+/Network+/Server+ (or equivalent), project management, audit and regulatory compliance (NCUA/FFIEC) experience.
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Information System Security Manager (ISSM)
Anaheim, California, United States
$96k-$182k/yr OnsiteFull Time
RTX
RTXNYSE: RTX: Provides advanced aerospace and defense systems and services.
5+ YOESTEM or IT degree and 5+ years of relevant DoD/IC cybersecurity experience. Requires active TS/SCI clearance, U.S. citizenship, ATO delivery experience, and expertise with RMF, STIGs, vulnerability tools, and classified systems.
ACAS, Nessus, SCAP, STIG Viewer, Splunk, SIEM, Linux, Windows, DevSecOps, Zero Trust, Identity Access Management
3d
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Information Systems Security Manager (ISSM) – Subject Matter Expert (SME) – TS/SCI
Los Angeles, California, United States
$130k-$150k/yr OnsiteFull Time
Vision Information Technology Consultants
Vision Information Technology Consultants: Provides specialized IT and cybersecurity services for government agencies.
12+ YOERequires active TS/SCI clearance and 12–20+ years of DoD or Air Force cybersecurity leadership experience, with expertise in RMF, NIST, STIGs, compliance, classified systems, and cybersecurity governance.
Risk Management Framework (RMF), NIST, STIG, enterprise cybersecurity tools, vulnerability management, continuous monitoring platforms
3mo
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Information Systems Security Officer, AD&S
Costa Mesa, California, United States
$113k-$149k/yr OnsiteFull Time
Anduril Industries
Anduril Industries: Defense technology building autonomous military hardware and software.
Design, implement, and oversee security controls per NIST RMF/JSIG; assess risks; manage security posture; ensure compliance.
Splunk, DISA STIGs, SCC, Python, PowerShell, Bash, Linux, SELinux
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Facilities Information System Manager
Universal City, California, United States
$90k-$125k/yr OnsiteFull Time
NBCUniversal
NBCUniversalNASDAQ: CMCSA: Produces and distributes entertainment content and theme park experiences.
3+ YOERequires 3+ years managing complex technology platforms, system-field mapping, data analysis, and system administration. Bachelor's degree in computer science, engineering, or related field is preferred.
Archibus, Integrated Workplace Management System (IWMS), Esri, Smart Client, Microsoft Excel, Standard Operating Procedures (SOPs), Service Level Agreements (SLAs)
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Chief Information Officer
Culver City, California, United States
$201k-$246k/yr HybridFull Time
Culver City
Culver City: Provides essential municipal services and public infrastructure to city residents.
6+ YOEBachelor's degree preferred in information systems, computer science, business administration, or related field, plus 6–10 years managing complex multi-user IT systems; additional experience may substitute.
Lean, Lean Six Sigma, Agile, Scrum, PMP, CGCIO, CISM, CISSP, CISA, Certified ScrumMaster, Microsoft 401(a) Plan, 457
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IT Systems Manager
Laguna Beach, California, United States
$70k-$82k/yr OnsiteFull Time
JC Resorts
JC Resorts: Manages and operates premium golf and resort properties.
Managing IT systems for a coastal luxury resort; position offers a base wage range and may be eligible for additional compensation.
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Manager, Laboratory Services (Information Systems) - Clinical Lab - Full Time 8 Hour Days (Exempt) (Non-Union)
Los Angeles, California, United States
$115k-$189k/yr RemoteFull Time
Keck Medicine of USC
Keck Medicine of USC: Provides specialized medical care and research via university health system.
5+ YOE1+ MgmtBachelor's degree, 5 years in acute care, 3 years as a laboratory information system analyst, 1 year supervisory experience, and familiarity with CAP, CLIA, LIS, management, and analytical problem-solving.
PowerChart, Cerner AP, Cerner CP, Kronos, PBAR, Master Control, Cerner, HL7, SQL, Co-path, PathNet, Excel, Word, PowerPoint, MDI, FSO, E”KM editor, Discern Visual Developer, Microsoft Word, Microsoft PowerPoint
2d
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Information Technology Administrator
Claremont, California, United States
$93k-$112k/yr OnsiteFull Time
City of Claremont
City of Claremont: Provides municipal services and public safety to Claremont residents.
5+ YOEFive years of progressive IT support experience or equivalent, a bachelor's degree in computer science or information systems, and a valid California driver's license. Network, systems, database, and enterprise infrastructure expertise required.
Microsoft Windows Server, Active Directory, Microsoft 365, Microsoft Entra ID, Microsoft Azure, VMware vSphere, VMware vCenter, Hyper-V, Fortinet, FortiGate, FortiSwitch, FortiAP, FortiManager, FortiAnalyzer, FortiAuthenticator, DNS, DHCP, VPN, VLANs, Exchange Online, MFA, Conditional Access, CAD/RMS, CJIS, CLETS
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Manager, Laboratory Services (Information Systems) - Clinical Lab - Full Time 8 Hour Days (Exempt) (Non-Union)
Los Angeles, California, United States
$115k-$189k/yr OnsiteFull Time
University of Southern California
University of Southern California: Private research university providing higher education and healthcare services.
5+ YOE1+ MgmtBachelor's degree, 5 years in acute care, 3 years as a laboratory information system analyst, 1 year supervisory experience, and familiarity with CAP and CLIA regulations required; analytical and communication skills required.
PowerChart, Cerner AP, Cerner CP, Kronos, PBAR, Master Control, Cerner, HL7, SQL, Co-path, PathNet, Excel, Microsoft Word, PowerPoint, MDI, FSO, E”KM editor, Discern Visual Developer
6d
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Business Systems Manager/Owner
Irvine, California, United States
$140k-$150k/yr OnsiteFull Time
Balt
Balt: Manufacturer of medical devices for treating neurovascular diseases
7+ YOERequires 7+ years in IT project management, product management, or business systems analysis; enterprise software implementations; BSA experience; SaaS, API, data mapping, Agile/Scrum, and project management expertise.
Jira, Confluence, Asana, Smartsheet, Agile, Scrum, ERP, CRM, QMS, HRIS, SaaS, API
2w
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Information System Security Officer
El Segundo, California, United States
$62k-$141k/yr HybridFull Time
Booz Allen Hamilton
Booz Allen HamiltonNYSE: BAH: Consulting and technology services for government and commercial clients
4+ YOEExperience managing RMF-based security controls in classified environments, TS/SCI clearance required, DoD 8140 baseline certifications (e.g., Security+ CE), 4+ years experience with information system security (or MS+2), incident response, assessments, and system hardening.
ACAS, HBSS, ESS, SPLUNK