44 it infrastructure manager jobs at 39 companies in Pacifica, CA
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IT Infrastructure Manager
South San Francisco, California, United States
$175k-$195k/yrOnsiteFull Time
Lyell ImmunopharmaNASDAQ: LYEL: Developing next-generation T-cell therapies for patients with solid tumors.
10+ YOEHands-on IT infrastructure expert with ~10+ years' experience across cloud (AWS), on-premises, networking, identity, collaboration, MSP oversight, backup/DR, security tooling, and enterprise AI platform governance in a regulated life-sciences environment.
AWS, VMware vSphere, Windows Server, Active Directory, Juniper, Cisco Meraki, Palo Alto Networks, Veeam, VPN, Okta, Microsoft 365, Zoom, Slack, EDR, SIEM, Anthropic Claude, Python, PowerShell, Ruby, Terraform, CloudFormation
Culver City or Austin or Seattle or San Jose or New York City or South America
$150k/yrOnsiteFull Time
Security Industry Specialists: Provides specialized security solutions for corporations and high-profile clients.
12+ YOE5+ MgmtBachelor's in IT/CS (or equivalent), 12+ years IT experience with 5+ years people leadership; cloud-first, macOS-focused infrastructure, identity and endpoint management, networking, SIEM, and ITIL experience required.
macOS, Windows, Google Workspace, Box, AWS, Microsoft Azure, Active Directory, Entra ID, Okta, Ping, JumpCloud, JAMF, Windows MDM, SentinelOne, Cisco Meraki, SIEM, Auvik, Make, n8n, Zapier
Jade Global: Provides IT consulting and enterprise software implementation services.
10+ YOE10+ years managing IT infrastructure and facilities projects; active PMP required; bachelor's degree in business, management, engineering, or IT; fluent written and verbal English and Spanish; strong vendor, budget, and stakeholder management.
Anaplan, Smartsheet, Microsoft Office 365, Zoom, CAD Viewer, Bluebeam, Microsoft Excel, Microsoft Project, Tableau, Microsoft PowerPoint, Lucidchart
Five9NASDAQ: FIVN: Provides cloud-based software for enterprise contact center operations.
10+ YOE5+ Mgmt10+ years IT experience with 5+ years leading global infrastructure and operations; deep experience across networking, IAM, cloud services, and Microsoft 365; cloud platform experience (Azure, AWS, GCP); people leadership and operating in regulated environments.
Microsoft Exchange Online, Microsoft Teams, Microsoft SharePoint, Microsoft OneDrive, Microsoft Intune, Microsoft Entra ID, Microsoft Purview, Microsoft Copilot, Azure, AWS, GCP, SD-WAN, ZTNA, VPN, SASE, Microsoft Enterprise Agreement
Nurix TherapeuticsNASDAQ: NRIX: Develops targeted protein degradation medicines for cancer and inflammation.
12+ YOE5+ Mgmt12+ years technology services leadership with 5+ years Director-level experience; experience across AWS, Microsoft Entra/Microsoft 365, cybersecurity operations, ITSM, and managing MSP portfolios.
AWS, Microsoft Entra, Microsoft 365, AWS ParallelCluster, SageMaker, EKS, ECS, RedCanary, Kroll, Arctic Wolf, Jira Service Management, ServiceNow
Stanford University: A private research university providing higher education and research.
8+ YOEBachelor's degree or equivalent experience plus eight years' experience managing mobile network connectivity, DAS, and private 5G; vendor management, leadership, and strong communication skills required.
eCMMS: Provides electronics packaging and reverse logistics for major manufacturers.
10+ YOE5+ MgmtBachelor's in a technical field,10+ years IT experience with 5+ years managing teams; experience in IT operations, infrastructure, cybersecurity, service delivery, and vendor/asset management.
NovaNASDAQ: NVMI: Provider of metrology and process control solutions for semiconductors.
Proven regional IT leadership managing business applications, infrastructure, and service delivery; hands-on systems analysis, Oracle Fusion experience, stakeholder management, and global/matrix organization experience.
EMCOR GroupNYSE: EME: Specialized mechanical and electrical construction and facilities services provider.
7+ YOE7+ years IT experience with strategic leadership, infrastructure and systems administration, Microsoft 365 and Active Directory proficiency, vendor management, security and compliance experience.
Director, Enterprise IT Infrastructure (CA, US, 95110)
San Jose, California, United States
$191k-$280k/yrOnsiteFull Time
QuantumScapeNYSE: QS: Develops next-generation solid-state batteries for electric vehicles.
15+ YOE5+ Mgmt15+ years IT experience with 5+ years leading enterprise infrastructure; Bachelor's in CS/IT/Engineering; hands-on expertise with GCP/Azure, Kubernetes (GKE), networking, identity, endpoints, SRE, automation, and OT/IT integration; strong leadership and cross-functional communication.
Skylo: Provides direct-to-device satellite connectivity for mobile and IoT devices.
6+ YOE2+ MgmtLead global corporate IT: manage infrastructure, IAM, MDM, SaaS, security/compliance, helpdesk, AI integration, disaster recovery; Bachelor's in CS/IT/CE; 6+ years IT experience with 2+ years managerial experience.
AuPairCare: Matches families with international au pairs for live-in childcare.
10+ YOE2+ MgmtBachelor's degree or equivalent IT experience; 10+ years of IT experience including 2+ years managing IT teams. Requires Google Workspace and Microsoft 365 administration, infrastructure, security, vendor, and budget management.
Google Workspace, Gmail, Google Drive, Google Calendar, Google Groups, Microsoft 365, Microsoft Exchange, Microsoft SharePoint, Microsoft Teams, Microsoft OneDrive, Microsoft Active Directory, OpenVPN, AWS, Cisco Meraki, Windows, Linux, VM, VPC, Proofpoint, Webroot, Microsoft Intune, JumpCloud, Huntress, Talkdesk, Zoho Desk, GCP
PenumbraNYSE: PEN: Designs and manufactures medical devices for vascular conditions.
15+ YOE8+ Mgmt15+ years IT infrastructure experience, bachelor’s in IT (or equivalent), supervisory experience, cloud and datacenter expertise, familiarity with QMS/security, and strong communication and leadership skills.
Microsoft Word, Microsoft Excel, Microsoft PowerPoint
Gener8: Designs and manufactures complex life science and medical instruments.
15+ YOE10+ MgmtSenior IT leader responsible for multisite IT infrastructure, security, and team management; requires extensive VMware/AD/O365 experience, cloud migration, and security governance.
Arcus BiosciencesNYSE: RCUS: Develops differentiated molecules and combination therapies to treat cancer.
10+ YOE3+ Mgmt10+ years in computer system validation in pharma/biotech, bachelor’s degree or equivalent, 3+ years people management preferred, hands-on GxP IT infrastructure and application validation, Veeva experience, strong regulatory knowledge.
Skywalker Vineyards: Produces estate wines and operates luxury hospitality services.
5+ YOE5+ years managing multi-site network and systems infrastructure, strong TCP/IP and LAN/WAN skills, Microsoft AD and 365 experience, virtualization, backup/DR, scripting with PowerShell, on-call availability.
Microsoft 365, Active Directory, Hyper-V, PowerShell, Microsoft Azure, Amazon Web Services, Box, Google Workspace, Zoom, Slack, Jamf Pro, Addigy, Zoom Rooms, Microsoft SQL Server, MySQL, FileMaker Server, EDR
Neurophos: Develops high-performance photonic processors for AI inference acceleration.
8+ YOERequires 8+ years in IT engineering or infrastructure, primary IT ownership at a company under 200 people, strong Linux, identity, networking, endpoint, cloud, MSP, scripting, and infrastructure-as-code experience.
Linux, EDA, CAD, Okta, SAML, SCIM, MFA, GitHub Enterprise, Google Workspace, Google Drive, Dropbox, Atlassian, IAM, VLAN, VPN, DNS, DHCP, macOS, Windows, Azure, Microsoft Excel, RDMA over Converged Ethernet (RoCE), InfiniBand, NIST Cybersecurity Framework, ISO 27001
10+ YOE5+ Mgmt10+ years in IT infrastructure/operations, 5+ years senior leadership, experience with hybrid cloud (AWS/Azure/GCP), SRE, ITSM/ITIL, vendor management, budgeting and retail technology (POS) preferred.