65 it infrastructure jobs at 57 companies in San Jose, CA

1mo
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IT Infrastructure Manager
South San Francisco, California, United States
$175k-$195k/yr OnsiteFull Time
Lyell Immunopharma
Lyell ImmunopharmaNASDAQ: LYEL: Developing next-generation T-cell therapies for patients with solid tumors.
10+ YOEHands-on IT infrastructure expert with ~10+ years' experience across cloud (AWS), on-premises, networking, identity, collaboration, MSP oversight, backup/DR, security tooling, and enterprise AI platform governance in a regulated life-sciences environment.
AWS, VMware vSphere, Windows Server, Active Directory, Juniper, Cisco Meraki, Palo Alto Networks, Veeam, VPN, Okta, Microsoft 365, Zoom, Slack, EDR, SIEM, Anthropic Claude, Python, PowerShell, Ruby, Terraform, CloudFormation
2mo
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Director, IT Infrastructure
Irving or San Ramon
$119k-$371k/yr HybridFull Time
Five9
Five9NASDAQ: FIVN: Provides cloud-based software for enterprise contact center operations.
10+ YOE5+ Mgmt10+ years IT experience with 5+ years leading global infrastructure and operations; deep experience across networking, IAM, cloud services, and Microsoft 365; cloud platform experience (Azure, AWS, GCP); people leadership and operating in regulated environments.
Microsoft Exchange Online, Microsoft Teams, Microsoft SharePoint, Microsoft OneDrive, Microsoft Intune, Microsoft Entra ID, Microsoft Purview, Microsoft Copilot, Azure, AWS, GCP, SD-WAN, ZTNA, VPN, SASE, Microsoft Enterprise Agreement
5d
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Sr. IT Infrastructure Engineer
South San Francisco, California, United States
OnsiteFull Time
Zipline
Zipline: Operates an autonomous drone delivery system for medical supplies.
7+ YOERequires 7+ years of IT experience, 5+ years administering infrastructure, SaaS, or identity systems, strong Python and Bash automation, enterprise IAM, API integrations, cloud infrastructure, and security expertise.
Okta, Google Workspace, Slack, Python, Bash, AWS, Google Cloud Platform, Iru, Jamf, Microsoft Intune, Hexnode, REST APIs, JSON, OAuth, SAML, SCIM, OpenID Connect (OIDC), GAM, Google APIs, Apps Script, Slack APIs, Terraform, Git, CI/CD
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Senior Manager of IT Infrastructure
Culver City or Austin or Seattle or San Jose or New York City or South America
$150k/yr OnsiteFull Time
Security Industry Specialists
Security Industry Specialists: Provides specialized security solutions for corporations and high-profile clients.
12+ YOE5+ MgmtBachelor's in IT/CS (or equivalent), 12+ years IT experience with 5+ years people leadership; cloud-first, macOS-focused infrastructure, identity and endpoint management, networking, SIEM, and ITIL experience required.
macOS, Windows, Google Workspace, Box, AWS, Microsoft Azure, Active Directory, Entra ID, Okta, Ping, JumpCloud, JAMF, Windows MDM, SentinelOne, Cisco Meraki, SIEM, Auvik, Make, n8n, Zapier
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Senior IT Infrastructure & Security Engineer
Sunnyvale, California, United States
$175k-$225k/yr OnsiteFull Time
Scout AI
Scout AI: Building the robotic foundation model for multi-domain defense.
7+ YOE7+ years network and infrastructure engineering; experience with CMMC/NIST SP 800-171, cloud (AWS/Azure), IaC, Linux/Windows administration, Python/Bash scripting, identity/access management, and compliance.
CMMC, NIST SP 800-171, AWS, Azure, Python, Bash, Linux, Windows
2d
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IT Infrastructure Platform Leader (Sr. Chief)
Saint Paul or Hopkins or Cupertino or New York City or Chicago or Gresham or Denver or Charlotte or Brookfield or Irving or Earth City
$150k-$176k/yr HybridFull Time
U.S. Bank
U.S. BankNYSE: USB: Provider of personal, business, and institutional financial services.
10+ YOEBachelor's degree or equivalent experience and 10+ years supporting mission-critical enterprise infrastructure; leadership in resilient platforms, operations, security, recovery, lifecycle management, vendors, and budgets.
HP NonStop, Tandem, Stratus Platforms, PSeries, AIX, IBM Z, Mainframe, Linux, x86, ITSM, E-Verify
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Director, IT Infrastructure & Operations
Brisbane, California, United States
$260k-$300k/yr OnsiteFull Time
Nurix Therapeutics
Nurix TherapeuticsNASDAQ: NRIX: Develops targeted protein degradation medicines for cancer and inflammation.
12+ YOE5+ Mgmt12+ years technology services leadership with 5+ years Director-level experience; experience across AWS, Microsoft Entra/Microsoft 365, cybersecurity operations, ITSM, and managing MSP portfolios.
AWS, Microsoft Entra, Microsoft 365, AWS ParallelCluster, SageMaker, EKS, ECS, RedCanary, Kroll, Arctic Wolf, Jira Service Management, ServiceNow
6d
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Intern, IT Infrastructure Support
Walnut Creek, California, United States
$20-$25/hr HybridFull Time, Internship
Canadian Solar
Canadian SolarNASDAQ: CSIQ: Manufactures solar modules and provides utility-scale energy storage solutions.
Working toward a computer science diploma or degree; familiarity with Microsoft solutions, IT processes, documentation, security practices, and project tools. Mandarin is highly desired.
Microsoft Autopilot, Microsoft Intune, Microsoft Windows, Microsoft 365, Microsoft Active Directory, Microsoft Azure, Conditional Access, Microsoft Planner, Jira, ITIL
6d
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IT Facilities & Infrastructure Project Manager
San Jose, California, United States
OnsiteFull Time
Jade Global
Jade Global: Provides IT consulting and enterprise software implementation services.
10+ YOE10+ years managing IT infrastructure and facilities projects; active PMP required; bachelor's degree in business, management, engineering, or IT; fluent written and verbal English and Spanish; strong vendor, budget, and stakeholder management.
Anaplan, Smartsheet, Microsoft Office 365, Zoom, CAD Viewer, Bluebeam, Microsoft Excel, Microsoft Project, Tableau, Microsoft PowerPoint, Lucidchart
2mo
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Director, Enterprise IT Infrastructure (CA, US, 95110)
San Jose, California, United States
$191k-$280k/yr OnsiteFull Time
QuantumScape
QuantumScapeNYSE: QS: Develops next-generation solid-state batteries for electric vehicles.
15+ YOE5+ Mgmt15+ years IT experience with 5+ years leading enterprise infrastructure; Bachelor's in CS/IT/Engineering; hands-on expertise with GCP/Azure, Kubernetes (GKE), networking, identity, endpoints, SRE, automation, and OT/IT integration; strong leadership and cross-functional communication.
GCP, Azure, Compute Engine, GKE, Cloud Storage, IAM, VPC, LAN/WAN, Wi-Fi, SD-WAN, Palo Alto firewalls, Kubernetes, SSO, MFA, MDM, EDR, ThreatLocker, Google Workspace, Microsoft 365, JIRA, ManageEngine, Cisco, OT/ICS, NIST CSF, ISO 27001, SOC 2, AIOps
2w
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IT Infrastructure Administrator
San Jose, California, United States
$115k-$130k/yr HybridFull Time
Frank Rimerman
Frank Rimerman: Provides accounting, tax, and advisory services to innovative businesses.
3+ YOE3+ years supporting enterprise Windows Server, Microsoft 365/Entra ID, VMware, backup solutions, networking (Cisco/Meraki), PowerShell automation, and LogicMonitor; bachelor\u0002s degree or equivalent experience; relevant industry certifications preferred.
Microsoft Active Directory, Group Policy, DNS, DFS, File Services, Microsoft 365, Exchange Online, Entra ID (Azure AD), OAuth, VMware vSphere, VxRail, Cohesity, AvePoint, Zerto, PKI, Mimecast, SPF, DKIM, DMARC, Microsoft Defender for Office 365, Abnormal Security, Cato SASE, LogicMonitor, PowerShell, Meraki, Cisco Umbrella/OpenDNS
2mo
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Senior IT Systems Engineer – Infrastructure & Automation
Menlo Park, California, United States
HybridFull Time
LeoLabs
LeoLabs: Provides orbital intelligence and space domain awareness services.
7+ YOESenior IT systems engineer focused on infrastructure, automation, and project leadership.
Windows, macOS, Microsoft 365, Entra ID, Office applications, Teams, SharePoint, Exchange, Licensing/Group management, PowerShell, Jamf Pro, Intune, Defender, Sentinel, Jira, Confluence, ITSM/ESM, VLANs, DNS, DHCP, VPN, RADIUS, NAC, 802.1X
2w
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Director IT Engineering
Alameda, California, United States
$200k-$300k/yr OnsiteFull Time
Penumbra
PenumbraNYSE: PEN: Designs and manufactures medical devices for vascular conditions.
15+ YOE8+ Mgmt15+ years IT infrastructure experience, bachelor’s in IT (or equivalent), supervisory experience, cloud and datacenter expertise, familiarity with QMS/security, and strong communication and leadership skills.
Microsoft Word, Microsoft Excel, Microsoft PowerPoint
1mo
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Mobile Infrastructure Technical Manager - IT
Stanford, California, United States
$160k-$191k/yr HybridFull Time
Stanford University
Stanford University: A private research university providing higher education and research.
8+ YOEBachelor's degree or equivalent experience plus eight years' experience managing mobile network connectivity, DAS, and private 5G; vendor management, leadership, and strong communication skills required.
ServiceNow
2d
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IT Business Partner
Palo Alto, California, United States
OnsiteFull Time
Rednote
Rednote: A lifestyle-focused social media and e-commerce discovery platform.
IT technology and service management experience, project management, troubleshooting, IT infrastructure and systems knowledge, English and Mandarin communication, and a bachelor's degree or equivalent experience.
IT infrastructure
2mo
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Director, IT and Cybersecurity
San Jose, California, United States
$151k-$252k/yr OnsiteFull Time
Gener8
Gener8: Designs and manufactures complex life science and medical instruments.
15+ YOE10+ MgmtSenior IT leader responsible for multisite IT infrastructure, security, and team management; requires extensive VMware/AD/O365 experience, cloud migration, and security governance.
Active Directory, Office 365, SharePoint, Teams, OneDrive, Intune, EMS, Hyper-V, VMware, Azure, Google Workspace, SolidWorks, Vault, Intune, Palo Alto Networks, Meraki, Cisco switches, Veeam, Cohesity, Okta, MFA, SD WAN, Proofpoint
5d
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Lead IT Engineer
Austin or Sunnyvale
$180k-$235k/yr OnsiteFull Time
Neurophos
Neurophos: Develops high-performance photonic processors for AI inference acceleration.
8+ YOERequires 8+ years in IT engineering or infrastructure, primary IT ownership at a company under 200 people, strong Linux, identity, networking, endpoint, cloud, MSP, scripting, and infrastructure-as-code experience.
Linux, EDA, CAD, Okta, SAML, SCIM, MFA, GitHub Enterprise, Google Workspace, Google Drive, Dropbox, Atlassian, IAM, VLAN, VPN, DNS, DHCP, macOS, Windows, Azure, Microsoft Excel, RDMA over Converged Ethernet (RoCE), InfiniBand, NIST Cybersecurity Framework, ISO 27001
2d
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IT Manager
Los Angeles County or Los Angeles or Sacramento or Oakland or Santa Ana or Orange or Rancho Cucamonga or Commerce or Sacramento
$9k-$13k/mo HybridFull Time
State Controller's Office
State Controller's Office: California's fiscal controller managing state financial operations and assets.
Supervises distributed IT support teams and enterprise service desk operations; requires IT infrastructure, ITIL, technical staff leadership, procurement, and resource management experience.
ITIL, Windows 11, Microsoft 365, Microsoft Excel
1w
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IT Manager
Santa Clara, California, United States
$125k-$165k/yr OnsiteFull Time
eCMMS
eCMMS: Provides electronics packaging and reverse logistics for major manufacturers.
10+ YOE5+ MgmtBachelor's in a technical field,10+ years IT experience with 5+ years managing teams; experience in IT operations, infrastructure, cybersecurity, service delivery, and vendor/asset management.
CCTV
2d
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IT Manager
San Francisco or Mountain View or South Bay
$160k-$250k/yr OnsiteFull Time
Triumph
Triumph: Skill-based mobile gaming platform for real money tournaments.
Hands-on corporate networking, endpoint management, Okta identity, physical office buildout, AI automation, infrastructure project ownership, and ability to work independently across offices.
Okta, Google Meet, Zoom, AI, MDM, VLANs, WiFi, SSO, MFA, RBAC