397 lead researcher jobs at 172 companies in Needham, MA

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Principal AI/ML Researcher
Boston, Massachusetts, United States
$270k-$300k/yr OnsiteFull Time
WHOOP
WHOOP: Wearable technology for personalized health and performance tracking.
Advanced degree or equivalent experience in large-scale ML, deep learning and multimodal research; proven record of taking research to production and leading technical direction.
transformers, state space models, PPO, DPO, GRPO
2mo
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Lead Signal Processing Researcher
Arlington or Dayton or Woburn or Boston or Melbourne or Carlsbad or United States
$173k-$216k/yr OnsiteFull Time
Systems & Technology Research
Systems & Technology Research: Develops advanced technology for national security and defense applications.
3+ YOEActive security clearance (US citizenship required), PhD/MS/BS in a technical discipline, 3+ years' relevant experience, strong MATLAB/Python/Simulink/C/C++ skills, expertise in signal processing, ML, radar, and systems integration.
MATLAB, Python, Simulink, C, C++
1d
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HPE Labs - Senior AI Researcher, Foundational AI
Milpitas or Westford or Spring or Andover
$152k-$349k/yr HybridFull Time
Hewlett Packard Enterprise
Hewlett Packard EnterpriseNYSE: HPE: Provides edge-to-cloud IT infrastructure and platform services.
5+ YOEPhD in a relevant technical field and 5+ years of post-PhD experience, with original AI/ML research, leading-venue publications, advanced Python and PyTorch proficiency, mathematical expertise, and strong experimental and software-engineering skills.
Python, PyTorch, C++, HPC, Monte Carlo simulations, density functional theory (DFT), molecular dynamics (MD)
6d
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Global Study Lead
Cambridge or Philadelphia
$145k-$196k/yr HybridFull Time
Alnylam
AlnylamNasdaq: ALNY: Developing and commercializing RNA interference (RNAi) therapeutics for diseases.
7+ YOE3+ MgmtBachelor's degree, 7+ years of clinical research experience, and 3–5 years leading global Phase 1–4 trials including Phase 3 registrational studies. Requires CRO oversight, leadership, project management, and Microsoft Office and Project proficiency.
Microsoft Office Suite, Microsoft Excel, Microsoft Word, Microsoft PowerPoint, Microsoft Project
2mo
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Clinical Science Lead - IL
Ramat Gan or Needham
HybridFull Time
Assured Allies
Assured Allies: Predictive analytics and wellness platforms for successful aging.
3+ YOEAdvanced degree in epidemiology/medical sciences; 3+ years digital health/outcomes research; solo functional owner; large datasets; Python/R; fluent English.
Python, R, Data analysis tools
1w
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Director, Study Lead (ClinOps)
Boston or San Diego
HybridFull Time
cAMPfield Therapeutics
cAMPfield Therapeutics: Clinical-stage biopharmaceutical developing oral therapies for inflammatory diseases.
10+ YOE5+ Mgmt10+ years clinical operations experience with 5+ years leading global Phase II/III studies, CRO oversight, ICH‑GCP knowledge, cross‑functional leadership, budget and resource management.
eCOA, IRT, TMF
2w
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Associate Director, Clinical Trial Lead
Billerica, Massachusetts, United States
$119k-$202k/yr HybridFull Time
Merck KGaA, Darmstadt, Germany
Merck KGaA, Darmstadt, GermanyFrankfurt Stock Exchange: MRK: A science and technology in healthcare, life sciences, and electronics.
7+ YOEBachelor's degree, 7+ years of clinical trial management, 5+ years of pharmaceutical or biotechnology clinical research, managerial experience, and strong leadership and project management skills.
ICH-GCP
1mo
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Senior Clinical Operations Lead
Cambridge, Massachusetts, United States
$152k-$191k/yr OnsiteFull Time
Sarepta Therapeutics
Sarepta TherapeuticsNASDAQ: SRPT: Develops precision genetic medicines for rare diseases.
7+ YOE4+ Mgmt7+ years clinical research experience with 4+ years study management; experience managing CROs/vendors; knowledge of FDA/EU regulations, ICH/GCP; bachelor's degree in health sciences or related; strong communication and MS Office/MS Project skills.
Excel, Word, PowerPoint, Outlook, MS Project
2mo
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Health Value Translation Lead
Cambridge, Massachusetts, United States
$179k-$258k/yr OnsiteFull Time
Sanofi
SanofiEuronext Paris: SAN: Researches, develops, and manufactures medicines and vaccines globally.
5+ YOEBachelor's degree; 5+ years in clinical development; experience in Real World investigations and patient preference research; understanding of payers environment in key markets; English fluency.
Digital Tools, Large Language Models, Social Media Listening
3w
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Lead Technologist
Boston, Massachusetts, United States
$65k-$83k/yr OnsiteFull Time
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute: Provides comprehensive cancer treatment and conducts oncological research.
3+ YOE3+ years in AAALAC-accredited lab animal facility, HS diploma/GED required (BA/BS preferred), AALAS LAT preferred, ability to perform injections, blood collection, animal handling, record keeping, and basic computer skills.
1w
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Global Asset Lead, Iqirvo
Cambridge or London or Paris
OnsiteFull Time
Ipsen
IpsenEuronext Paris: IPN: Develops medicines for oncology, neuroscience and rare diseases.
5+ YOEAdvanced degree (MD/PhD/MBA) and 5+ years global project leadership in biotech/pharma; experience leading matrix teams, cross-functional asset strategy, and oncology expertise.
1mo
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Director, CMC Lead
Bedford or Waltham
$225k-$250k/yr HybridFull Time
Stoke Therapeutics
Stoke TherapeuticsNASDAQ: STOK: Develops RNA-based therapies for severe genetic disorders.
10+ YOE5+ Mgmt10+ years CMC experience with drug-device combination products, 5+ years CMC leadership, bachelor's required (advanced degree preferred), deep CMC/regulatory knowledge, strong communication and cross-functional leadership.
1w
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Director, Translational Medicine Clinical Lead-Immunology
Spring House or San Diego or Cambridge
$199k-$398k/yr HybridFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Provides pharmaceutical products and medical technology healthcare solutions.
3+ YOEMD or MD/PhD, ≥3 years industry/translational research, clinical leadership experience, training in immunology and early clinical development, publication track record, willingness to travel (~10%).
5d
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Global Study Lead
United States or Philadelphia or Cambridge
$145k-$196k/yr HybridFull Time
Alnylam Pharmaceuticals
Alnylam PharmaceuticalsNASDAQ: ALNY: Develops RNAi therapeutics to treat rare and common diseases.
7+ YOE3+ MgmtRequires a bachelor's degree, 7+ years of clinical research experience, 3–5 years leading global trials, Phase 3 experience, CRO oversight, leadership, project management, and MS Office/MS Project proficiency.
Microsoft Excel, Microsoft Word, Microsoft PowerPoint, Microsoft Project
6d
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Global Study Lead
Cambridge or Philadelphia
$145k-$196k/yr HybridFull Time
Alnylam Pharmaceuticals, Inc.
Alnylam Pharmaceuticals, Inc.: A biopharmaceutical developing RNA interference therapeutics for rare and common diseases.
7+ YOEBachelor's degree required; 7+ years of clinical research experience, 3–5 years leading global trials, Phase 3 registrational trial experience, CRO oversight, leadership, budgeting, and MS Office/MS Project proficiency.
Microsoft Office Suite, Microsoft Excel, Microsoft Word, Microsoft PowerPoint, Microsoft Project
2mo
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Technical Lead, Raw Materials
Pawtucket, Rhode Island, United States
OnsiteFull Time
Teknor Apex
Teknor Apex: Manufactures custom plastic compounds and chemicals for various industries.
7+ YOE7+ years in plastics/polymers or related technical roles, bachelor's degree in a related field, prior technical or people leadership preferred, strong polymer/raw material knowledge, project management, MS Office proficiency, and ability to lead AI-enabled problem solving.
Microsoft Office Suite
1w
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Director, Translational Medicine Clinical Lead-Immunology
Spring House or San Diego or Cambridge
$199k-$398k/yr HybridFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Develops and manufactures pharmaceutical drugs and medical devices.
3+ YOEMD or MD/PhD required, minimum 3 years industry/translational research experience, supervisory experience, training in immunology preferred, experience with biologic or immune cell therapies preferred, strong publication record preferred, willingness to travel (~10%).
1w
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Associate Director, CMC Lead
Boston, Massachusetts, United States
$137k-$205k/yr HybridFull Time
AstraZeneca
AstraZenecaLondon Stock Exchange: AZN: Researches and develops medicines to treat major diseases globally.
7+ YOE7+ years pharmaceutical/biopharma CMC development and manufacturing experience; Bachelor\u0002s required (advanced degree preferred); IND-enabling and process/analytical development experience; cross-functional leadership and strategic decision-making.
1w
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Associate Director, CMC Lead
Boston, Massachusetts, United States
$137k-$205k/yr HybridFull Time
AstraZeneca
AstraZenecaLondon Stock Exchange: AZN: Researches, develops, and manufactures prescription medicines for major diseases.
7+ YOE7+ years pharmaceutical/biopharma CMC experience, bachelor\u0002s required (advanced degree preferred), IND/IMPD and IND-enabling experience, process and analytical development, cross-functional leadership and regulatory authorship experience.
1mo
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Global Medical Lead, Nephrology
Cambridge or Boston
$192k-$302k/yr HybridFull Time
Takeda
TakedaTokyo Stock Exchange / New York Stock Exchange: 4502 / TAK: Researches, develops, and manufactures prescription pharmaceutical medicines.
5+ YOE5+ years biopharma medical affairs experience, experience in nephrology/IgAN preferred; MD/DO/PhD preferred; global medical strategy, launch readiness, cross-functional leadership, and knowledge of regulatory environment.