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82 lead system engineer jobs at 48 companies in Lancaster, PA

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Manufacturing Execution System Automation Lead
Malvern or Spring House
$94k-$145k/yr OnsiteFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Provides pharmaceutical products and medical technology healthcare solutions.
6+ YOEBachelor's in engineering, 6+ years MES experience (PAS-X preferred), strong communication, decision-making and problem-solving, GxP/cGMP experience preferred, knowledge of OSI PI and MES-automation integration.
PAS-X, MES, OSI PI
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2mo
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CSV Lead/ Computer System Validation Lead
Marietta, Pennsylvania, United States
OnsiteFull Time
GBA
GBA: Provides engineering, architecture, and construction services for infrastructure.
10+ YOEBS in engineering, 10+ years project/process engineering or production experience, pharmaceutical/GMP experience, Kneat preferred, strong communication and problem-solving, MS Office proficiency.
Kneat, Microsoft Excel, Microsoft Word, Microsoft Project, Microsoft PowerPoint, Microsoft Access
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2mo
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System Architect, Mid-Career
Huntsville or King of Prussia or Littleton or Sunnyvale
$119k-$237k/yr OnsiteFull Time
Lockheed Martin
Lockheed MartinNYSE: LMT: Designs and manufactures global security and aerospace systems.
Experience in systems architecture/engineering, leading multi-disciplinary teams, performing trade studies and system modeling, SECRET clearance required, and willingness to obtain LM Systems Architect certification within 12 months; MBSE, DOORS, and Cameo experience preferred.
DOORS, Cameo, Model-Based Systems Engineering
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Lead Systems Engineer
Aberdeen, Maryland, United States
$124k/yr OnsiteFull Time
DCS Corporation
DCS Corporation: Providing engineering and technical services for national security.
12+ YOEU.S. citizenship and TS/SCI clearance required. Bachelor's in engineering and 12 years related experience. DAU level systems engineering certification desired.
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Manufacturing Execution System Automation Lead
Malvern or Spring House
$94k-$145k/yr OnsiteFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Global healthcare providing pharmaceuticals and medical technologies.
6+ YOEBachelor's in engineering, 6+ years MES experience (PAS-X), GxP regulated environment experience, MES implementation/validation skills, strong communication, decision-making, and leadership abilities.
PAS-X, OSI PI
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Manufacturing Execution System Automation Lead
Malvern or Spring House
$94k-$145k/yr OnsiteFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Develops and manufactures pharmaceutical drugs and medical devices.
6+ YOEBachelor's in engineering required, minimum 6 years MES experience, PAS-X experience required, validation and GxP experience, strong communication and problem-solving, knowledge of MES-automation integration and OSI PI preferred.
PAS-X, MES, OSI PI
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Lead Design Engineer (New Castle, DE, US)
New Castle, Delaware, United States
HybridFull Time
Alstom
AlstomEuronext Paris: ALO: Manufactures high-speed trains, signaling systems, and railway infrastructure
3+ YOEBachelor's degree in engineering (or equivalent) with strong electrical background, mandatory PCB exposure, minimum 3 years engineering/system experience, failure analysis and test development experience, leadership/team lead ability.
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3w
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Systems Integration Lead/Sr Systems Engineer
Aberdeen Proving Ground, Maryland, United States
OnsiteFull Time
SAIC
SAICNASDAQ: SAIC: Provides government and defense clients with technology and engineering services.
14+ YOEBachelor's in systems or related engineering + 14 years' experience; expertise in systems integration, IT architecture or SIGINT; IC/DoD program experience; leadership of multi-disciplinary teams; active TS/SCI required.
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2w
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Lead Product Development Engineer, R&D
Marlborough or Newark
$119k-$187k/yr OnsiteFull Time
Hologic
HologicNASDAQ: HOLX: Develops medical technology for women's healthcare and diagnostics.
8+ YOELead complex regulated medical device product development, design control, risk management (ISO 14971), V&V, and design transfer; strong systems engineering, manufacturing and DFx experience.
ISO 14971, ISO 13485, DFSS, DOE, Minitab, GD&T, SolidWorks
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Sr. Systems Engineer, ICM App Lead
Aberdeen Proving Ground, Maryland, United States
$150k-$195k/yr OnsiteFull Time
QED Systems
QED Systems: Provides engineering and technical services for defense C5ISR systems.
15+ YOE15+ years related experience, bachelor’s degree in engineering or related field, active Top Secret/SCI clearance, DoD systems engineering experience, strong technical and communication skills.
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3w
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Systems Integration Lead/Sr Systems Engineer
Aberdeen Proving Ground, Maryland, United States
$160k-$200k/yr OnsiteFull Time
SAIC
SAICNYSE: SAIC: Provides engineering, IT, and mission support services to government.
14+ YOEBachelor's in systems engineering or similar with 14 years' experience, TS/SCI clearance required, expertise in systems integration/IT/SIGINT, experience with ISR/C4ISR programs, leadership and program management skills.
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Lead Electrical Engineer 1 - Nuclear
Wilmington, Delaware, United States
$118k-$180k/yr OnsiteFull Time
Sargent & Lundy
Sargent & Lundy: Provides engineering and consulting services for the power industry.
10+ YOE3+ MgmtABET-accredited BS in electrical engineering, 10+ years designing electrical systems for power plants, 3+ years leading design groups, experience with LV/MV distribution and power studies, proficiency with MS Office; PE licensure preferred; must be able to be badged for unescorted nuclear access. Employer does not sponsor work authorization.
Microsoft Office, Microsoft Excel, Python, MATLAB
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3w
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Lead Instrumentation & Controls Engineer 1 - Nuclear
Wilmington, Delaware, United States
$118k-$180k/yr OnsiteFull Time
Sargent & Lundy
Sargent & Lundy: Engineering and consulting services for the power industry.
10+ YOEABET-accredited BS in engineering, 10+ years I&C design experience for heavy industrial/nuclear plants, experience with PLC/DCS/HSI and system design, ability to lead teams and review designs.
PLC, DCS, HSI, Python, MATLAB, Microsoft Excel
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Process Engineering Lead
Newark, Delaware, United States
$89k-$152k/yr OnsiteFull Time
Coherent
CoherentNYSE: COHR: Manufactures lasers, engineered materials, and optical networking components.
3+ YOELead engineering projects and teams; supervisory experience in engineering/manufacturing; knowledge of ceramic fabrication, CNC programming, metrology, ISO quality systems; 3–12 years experience depending on degree/equivalency.
CNC, ISO 9000, ISO 9001, ISO 14001
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2w
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Lead Electrical Controls Engineer
Honey Brook, Pennsylvania, United States
OnsiteFull Time
R-V Industries
R-V Industries: Manufactures custom industrial process equipment and pressure vessels.
Design, develop, and validate PLC-based control systems; ladder logic and RS Logix experience; AutoCAD and technical writing; familiarity with NEC, NFPA79, P&ID and cGMP validation protocols; BS in EE or related.
PLC, Ladder Logic, RS Logix 500, RS Logix 5000, Mitsubishi, Compactlogix, Micrologix, Unitronix, Proface, PanelView, PanelView+, AutoCAD, MS Office
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1d
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Lead Engineer, Embedded Software
Towson, Maryland, United States
$111k-$178k/yr HybridFull Time
Stanley Black & Decker
Stanley Black & DeckerNYSE: SWK: Manufacturer of power tools, hand tools, and outdoor equipment.
10+ YOE10+ years electronics and embedded firmware experience, 5+ years bare-metal embedded design, proficiency in C/C++/ASM and ARM, motor control and li-ion battery experience, RTOS and peripheral knowledge, strong debugging and system-level skills.
C, C++, ASM, ARM, RTOS, unit testing, static analysis, distributed version control, in-circuit debugger, Agile
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Sr Engineer - Electrical T&S Standard Ownership
Newark, Delaware, United States
$103k-$142k/yr HybridFull Time
Exelon
ExelonNASDAQ: EXC: Electric utility holding delivering energy to customers.
7+ YOEBachelor's in Engineering or PE license, 7+ years professional engineering experience, expertise in electrical systems, standards/codes (NERC PRC/CIP), ability to analyze complex systems and lead technical projects.
CYMDIST, Python, Power BI, Aspen Relay Database, Aspen Oneliner
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Sr Engineer - Electrical T&S Standard Ownership
Newark, Delaware, United States
$103k-$155k/yr OnsiteFull Time
Pepco
PepcoNASDAQ: EXC: Provides regulated electric utility services to Washington D.C. and Maryland.
7+ YOEBS in Engineering or PE,7+ years engineering experience,knowledge of electrical systems,standards and codes,ability to lead projects and perform technical assessments.
CYMDIST, Python, Power BI, Aspen Relay Database, Aspen Oneliner
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Senior Project Engineer
Wilmington, Delaware, United States
$120k-$150k/yr HybridFull Time
Mantis Innovation
Mantis Innovation: Provides managed facility services and energy procurement solutions.
5+ YOEBachelor's in engineering, 5+ years experience in utility system modernization or energy efficiency, industrial/commercial project experience, technical HVAC/utility expertise, ability to lead engineering design, perform site surveys, and deliver investment-grade recommendations.
HVAC, BMS/BAS
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Lead Software Engineer-AI
Columbus or Wilmington
OnsiteFull Time
JPMorgan Chase
JPMorgan ChaseNYSE: JPM: Global financial services firm providing banking and investment solutions.
7+ YOE7+ years applied software engineering experience; strong system design and production engineering skills; proficiency in Python or TypeScript; experience with agent frameworks (e.g., LangChain, LlamaIndex), LLM API integration, cloud-native systems, and evaluating reliability/observability.
Python, TypeScript, LangChain, LlamaIndex, AutoGen, CrewAI, Cloud Foundry, GKP, Jules CI/CD, TrueCD, Sophia auth
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