117 medicinal chemistry jobs at 80 companies in United States
1d
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Director, Medicinal Chemistry
South San Francisco, California, United States
$207k-$250k/yr HybridFull Time
8+ YOEPhD in Chemistry and 8+ years of pharma or biotech drug discovery experience, with medicinal chemistry leadership, development candidate delivery, team management, and strong scientific communication skills.
2mo
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Director, Medicinal Chemistry
Newark, California, United States
$210k-$250k/yr OnsiteFull Time
10+ YOEPhD in synthetic organic or medicinal chemistry, 10+ years drug discovery experience, leadership of medicinal chemistry teams, expertise in synthetic and medicinal chemistry, ADME/PK/DMPK, CRO management, IP and analytical separations experience.
computational and structural biology, molecular modeling, HPLC, RP-HPLC, LC/MS, ion exchange chromatography, size-exclusion chromatography, ADME/PK, DMPK
1mo
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Principal Scientist, Medicinal Chemistry
San Diego, California, United States
$131k-$179k/yr OnsiteFull Time
4+ YOEAdvanced medicinal chemistry expertise with 4+ years industrial experience (varies by degree), strong organic synthesis, lab automation and data analysis skills, publication/patent record, leadership and project management experience.
automated synthesis, parallel synthesis, lab automation
2mo
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Scientist, Medicinal Chemistry
San Francisco, California, United States
OnsiteFull Time
PhD in medicinal chemistry or related field; strong experience in small-molecule drug discovery and IP collaboration.
Molecular design, Synthesis, SAR analysis, DMPK, PK/PD, Cell-based assays, PPI assays, BioID/ABRID
1mo
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Scientist / Senior Scientist, Medicinal Chemistry
San Francisco, California, United States
$140k-$220k/yr OnsiteFull Time
5+ YOE5+ years industry experience in medicinal or synthetic organic chemistry; ownership of compound design through synthesis, purification, and characterization; experience with HPLC/LC-MS and troubleshooting; strong experimental judgment and communication.
HPLC, Prep HPLC, LC-MS, Microwave-assisted synthesis systems
1mo
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Director/Sr. Director, Medicinal Chemistry
Palo Alto, California, United States
$230k-$300k/yr OnsiteFull Time
10+ YOE10+ years leading medicinal chemistry programs from hit-to-lead through candidate nomination; expertise in SAR, structure-based design, ADME/PK optimization, synthetic strategy, and CRO/CDMO oversight; PhD preferred.
FEP, docking, crystallography
1w
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Principal Scientist, Medicinal Chemistry
Watertown, Massachusetts, United States
$179k-$200k/yr HybridFull Time
5+ YOEBS in chemistry,5+ years industry experience with peptide and small-molecule synthesis, experience advancing hits to development candidates, leadership of external chemists, computational modeling experience.
Spotfire
1mo
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Senior Director, AIRx Medicinal Chemistry
Boston or Cambridge
$212k-$333k/yr HybridFull Time
12+ YOEPhD in medicinal or organic chemistry; 12+ years drug discovery experience in lead optimization and candidate nomination; strong SAR, ADME and MPO skills; CRO oversight; able to evaluate and challenge AI/ML design outputs and apply structure-based design.
AI/ML
3d
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Senior Director, Medicinal Chemistry Design
Cambridge, Massachusetts, United States
$240k-$295k/yr OnsiteFull Time
12+ YOEPhD in chemistry with 12+ years of industrial experience or master's degree with 15+ years; drug candidate delivery, medicinal chemistry leadership, program leadership, degraders, structure-based analysis, hypothesis-driven design, and AI tool proficiency.
AI design platform, machine learning, AI
2mo
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Faculty - School of Pharmacy - Medicinal Chemistry
Worcester, Massachusetts, United States
OnsiteFull Time
PhD in medicinal chemistry or related discipline, prior college-level teaching, record of scholarship, ability to use DE/online teaching technology, proficiency with Blackboard and ExamSoft, strong communication and organizational skills.
Blackboard, ExamSoft
5d
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Director/Sr. Director - Medicinal Chemistry (synthetic macrocycles)
San Francisco or Indianapolis or South San Francisco or San Diego or Louisville or Alcobendas
$164k-$282k/yr OnsiteFull Time
8+ YOEPh.D. plus 8+ years of pharmaceutical or biotechnology drug discovery experience, or BS/MS plus 15+ years equivalent experience; expertise in synthetic macrocycles, medicinal chemistry, and ADME/DMPK.
Electronic Laboratory Notebooks (ELN), AI, ML
1mo
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Associate Director/Director, Medicinal Chemistry
San Francisco, California, United States
$160k-$240k/yr OnsiteFull Time
7+ YOEPhD in chemistry (or BS with extensive experience) with 7+ years industrial medicinal chemistry experience, deep SBDD and ADME expertise, program leadership and external team management, strong communication and mentorship skills.
1d
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Scientist, Medicinal Chemistry
Foster City, California, United States
$147k-$190k/yr OnsiteFull Time
4+ YOEBachelor's degree with 6 years' experience or master's degree with 4 years' experience; PhD in molecular chemistry preferred. Requires synthesis, medicinal chemistry, communication, and collaboration skills.
1d
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Scientist, Medicinal Chemistry
Foster City, California, United States
$147k-$190k/yr OnsiteFull Time
4+ YOEBachelor’s degree with 6 years of experience or master’s degree with 4 years; PhD in molecular chemistry preferred. Requires medicinal chemistry expertise, synthesis problem-solving, scientific literature knowledge, and communication skills.
Workday
1mo
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Principal Research Scientist - Medicinal Chemist
Indianapolis, Indiana, United States
HybridFull Time
6+ YOEPhD in medicinal/organic chemistry, 6+ years industry medicinal chemistry experience, expertise in small-molecule design and multi-step synthesis, SAR and ADME/PK, experience with DEL, computational chemistry or AI/ML, CRO coordination, and mentoring.
AI/ML, DNA-Encoded Libraries (DEL), computational chemistry
3w
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Computational Medicinal Chemist
San Diego, California, United States
$126k-$257k/yr HybridFull Time
3+ YOEPhD in medicinal/computational chemistry or related field (MS with 6+ years considered),3+ years drug-discovery experience, proven analogue design impact, familiarity with computational drug-design tools, strong communication and data-visualization skills.
Schrdoinger, CCG, OpenEye, Python
3w
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Computational Medicinal Chemist
San Diego, California, United States
$126k-$257k/yr HybridFull Time
3+ YOEPhD in medicinal/computational chemistry or related field (MS with 6+ years considered),3+ years drug discovery experience, track record in analogue design, familiarity with computational drug design tools and HPC, strong communication and data visualization skills.
Schrdoinger, CCG, OpenEye, high-performance computing environments, Electronic lab imaging (imaging techniques)
4d
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Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA
Cambridge, Massachusetts, United States
HybridFull Time
5+ YOEPhD or equivalent industrial experience; 5+ years in medicinal chemistry within biotech, pharma, or CRO settings; project leadership, structure-based drug design, CRO management, and strong scientific communication required.
AlphaFold, machine learning
3d
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Postdoctoral Fellow: Medicinal Chemistry & Drug Discovery
Detroit, Michigan, United States
$55k-$63k/yr OnsiteFull Time
PhD in organic, medicinal, or related chemistry preferred; experience synthesizing and evaluating small-molecule inhibitors, chemical method development, pharmacokinetics, hit-to-lead optimization, collaboration, and mentoring preferred.
O-GlcNAc transferase (OGT), SAR, PK
1mo
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Head of Chemistry
Lexington or Korea
OnsiteFull Time
5+ YOE5+ MgmtPh.D. or equivalent in organic or medicinal chemistry, ADC or degrader-conjugate chemistry expertise, and 5–10 years of leadership experience managing cross-disciplinary scientific teams.
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