33 mes manager jobs at 23 companies in Ephrata, PA
2mo
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Project Manager
Philadelphia or Newark or Virginia
HybridFull Time
5+ YOE5+ years project management in manufacturing/industrial automation; MES, automation projects; SCADA/Controls; PMI/PMP; MS Project; engineering background preferred.
MS Project, Gantt charts, MES, SCADA, HMI, PLC
1mo
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Project Manager – Valley Forge
Norristown, Pennsylvania, United States
OnsiteFull Time
3+ YOE3+ years experience with control systems in manufacturing; proven project delivery skills; knowledge of PLC/HMI/SCADA/DCS/MES; strong communication and MS Office proficiency.
PLC, HMI, SCADA, DCS, MES, Microsoft Office
2mo
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Plant Manager / Production
Souderton, Pennsylvania, United States
OnsiteFull Time
5+ YOE5+ MgmtLead plant operations with 5+ years food/meat processing leadership; ensure USDA/FSIS and HACCP compliance; manage production, safety, quality, ERP/MES reporting, and people; HS required, Bachelor’s preferred.
ERP, MES, HACCP, SSOP, GMP, 5S, Lean
3w
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Portfolio & Program Manager
Marietta, Pennsylvania, United States
OnsiteFull Time
6+ YOEBS/BA in relevant field, 6+ years program/portfolio management experience in regulated manufacturing, 3+ years using Microsoft Projects and Power-BI, strong risk and cross-functional leadership skills.
Microsoft Projects, Power-BI Dashboards, MES, eBR
2mo
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Production Control Manager
Aberdeen, Maryland, United States
$63k-$139k/yr OnsiteFull Time
6+ YOE2+ MgmtAA/AS degree in related field,6+ years manufacturing/repair plant experience,2+ years supervisory experience,knowledge of production planning,ERP/MRP/MES,maintenance coordination,and safety/quality compliance.
ERP, MRP, MES
2w
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Business Unit Productivity Manager - Traveling Remote Position
Lancaster, Pennsylvania, United States
$110k-$165k/yr FieldFull Time
5+ YOE5+ years in manufacturing/operations or industrial engineering; experience with Lean/Six Sigma, process improvement, KPI analysis, MES/ERP and reporting tools; preferred extrusion blow molding experience.
MES, AI, IFP, Streamline, Infinity ERP, Power BI, Microsoft Excel, SAP, MRP
1mo
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Tooling and Equipment Design & Build Manager
Wyomissing, Pennsylvania, United States
OnsiteFull Time
10+ YOE10+ years in tooling, machining, or equipment design/build with leadership experience; proficiency in SolidWorks, CNC/EDM, PLCs, and ERP/MES; strong machining, automation, safety, and regulatory knowledge.
SolidWorks, CNC, EDM, PLC, ERP, MES
1w
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Sr Manager, QC & Calibrations
Elkton, Maryland, United States
$144k-$202k/yr OnsiteFull Time
Requires advanced quality systems, cGMP, FDA, ISO, calibration, metrology, CAPA, audit, inspection, risk management, statistical analysis, and cross-functional leadership expertise in regulated manufacturing.
MES
2mo
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Manufacturing Manager (Weekend Shift)
Newark, Delaware, United States
$89k-$127k/yr OnsiteFull Time
6+ YOELeads manufacturing team; 6+ years in high-volume manufacturing; Lean, ERP, WMS; strong analysis and leadership.
ERP, Oracle WMS, MES, Lean Manufacturing, Excel
2mo
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Manufacturing Execution System Automation Lead
Malvern or Spring House
$94k-$145k/yr OnsiteFull Time
6+ YOEBachelor's in engineering, 6+ years MES experience (PAS-X preferred), strong communication, decision-making and problem-solving, GxP/cGMP experience preferred, knowledge of OSI PI and MES-automation integration.
PAS-X, MES, OSI PI
1mo
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Core Ops Digital & Automation Lead (Myerstown, Pennsylvania, US)
Myerstown, Pennsylvania, United States
$85k-$127k/yr OnsiteFull Time
Bachelor's or master's in manufacturing/engineering/supply chain/operations; deep manufacturing/packaging/supply chain experience; leadership and change-management experience; strong analytics and regulatory (GMP/OSHA/EPA) knowledge; MES/automation familiarity.
Manufacturing Execution Systems (MES), AI (Artificial Intelligence)
2mo
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Manufacturing Execution System Automation Lead
Malvern or Spring House
$94k-$145k/yr OnsiteFull Time
6+ YOEBachelor's in engineering required, minimum 6 years MES experience, PAS-X experience required, validation and GxP experience, strong communication and problem-solving, knowledge of MES-automation integration and OSI PI preferred.
PAS-X, MES, OSI PI
1mo
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Core Ops Digital & Automation Lead
Myerstown, Pennsylvania, United States
$85k-$127k/yr OnsiteFull Time
Bachelor's degree in Manufacturing, Engineering, Supply Chain, or Operational Excellence required; deep multifunctional manufacturing/packaging/supply chain experience; experience with digitalization, MES, electronic batch records, data analytics/AI, change management and leadership.
Manufacturing Execution Systems (MES), Artificial Intelligence (AI), electronic batch records
1w
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Regional Chief Operating Officer
York, Pennsylvania, United States
OnsiteFull Time
10+ YOEEngineering or industrial management degree, 10+ years in senior EPC or manufacturing operations, international multi-site leadership, ERP/MES and supply chain expertise, and frequent regional travel.
ERP, MES
1mo
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Enterprise Applications Architect
Malvern or Turin
HybridFull Time
8+ YOE8+ years in enterprise application architecture with extensive SAP expertise, integration experience (MES/PLM/ERP/cloud), strong process mapping and application rationalization skills, and leadership/communication ability.
SAP S/4HANA, ECC, SAP BTP, SAP Analytics, SAP Integration Suite, MuleSoft, MES, PLM, CRM, EDI, JDE, Avante, Epicor, ServiceNow, Azure, AWS, GCP
1mo
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Operational Excellence Lead: BioVectra
Boston or Folsom or Philadelphia or Wilmington or Kirkland or North Carolina or Colorado or Texas or California or Durham or Cedar Creek or Frederick or Canada or Ontario or Greater Toronto Area or Canada or Prince Edward Island or Nova Scotia or New Brunswick or Charlottetown
$147k-$275k/yr FieldFull Time
10+ YOEBachelor's or master's in life science/chemical/biochemical engineering,10+ years in GMP/regulated production with microbial fermentation and downstream purification, hands-on production-system deployment experience, strong problem-solving and coaching skills.
MES, Electronic batch records, shop-floor data systems, AI
2mo
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IODT Solution Delivery Leader
Wilmington or Cheonan or Hsinchu City
HybridFull Time
10+ YOE10+ years in manufacturing IT/OT delivering MES at multiple sites; lead global teams; experience with MES platforms; AI in manufacturing; ISA-95/ISA-88; cloud; Agile/SAFe; Bachelor’s in CS/Engineering; fluent English.
Critical Manufacturing, AVEVA, TrackSys, Rockwell FactoryTalk, GE Proficy, iBASEt, Tulip, Microsoft Power Automate, Visio, microservices, event-driven, modern web/UX
1w
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Area Manager Intern - Summer 2027 (NY, NJ, PA, DE, MD, CT, MA, NH, RI, VT, ME)
North Haven or Middletown or Wilmington or Stoughton or Sparrows Point or Somerset or Fishkill or Rochester or Hamburg or Johnston
$29/hr OnsiteMultiple Commitments Available
Current bachelor's student completing requirements December 2027–August 2028; requires leadership potential, communication, customer service, and interpersonal skills.
pallet jacks, PIT equipment
6d
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Global Automation Engineering & Technology Head
Kankakee or King of Prussia or Waltham
OnsiteFull Time
15+ YOEBachelor's degree in engineering, automation, computer science, or equivalent; 15+ years' experience, including 5+ in execution systems and OT; expertise in automation, MES, regulated manufacturing, leadership, and GxP compliance.
OSI Pi, LIMS, Enterprise MES, Edge, Configuration management, DCS, SCADA, ISA-88, ISA-95, Pharma 4.0, GAMP 5, 21 CFR Part 11, Annex 11, AI/ML, Digital twins, Cloud, Siemens, Starlims, Aveeva, Mescada, CapG, Avacone, Cognizant
1w
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Computer System Validation
Wilmington, Delaware, United States
$125k-$150k/yr OnsiteFull Time
8+ YOE8+ years CSV experience in GxP environments, knowledge of Part 11/Annex 11, authoring validation deliverables, risk-based validation, and stakeholder management.
GAMP 5, LIMS, MES, QMS, ERP, DMS, cloud/SaaS applications
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