600 operational excellence manager jobs at 371 companies in Upton, MA
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Manager, Business Operational Excellence
Worcester, Massachusetts, United States
$175k-$209k/yr OnsiteFull Time
3+ YOEMaster's in bio(chemical) engineering or related +3 years or Bachelor's +5 years in pharma/medical device operational improvements; Six Sigma Green Belt; experience driving manufacturing operational excellence and cross-functional collaboration.
1w
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Global Operational Excellence Lead
Quincy or Princeton or Irvine or Austin or Atlanta or Boston or Sacramento
$120k-$203k/yr HybridFull Time
12+ YOE7+ Mgmt12+ years in cyber security or technology operations, 7+ years in production/ service management; expertise in public cloud, ITIL/ITSM, SRE/DevOps, operational governance, audit readiness, and AI-enabled automation.
AWS, Azure, GCP, SIEM, Security Lakehouse, SOAR, AI, SRE, DevOps, ITOM, ITSM, ITIL
2w
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Operational Excellence Lead
Boston or Cambridge
$116k-$182k/yr HybridFull Time
Bachelor's or Master's required; Lean/Six Sigma Black Belt; experience in matrix, cross-regional teams; contract management, process improvement, strong communication and leadership skills.
1mo
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Director, U.S. Operational Excellence
Cambridge, Massachusetts, United States
$177k-$260k/yr OnsiteFull Time
12+ YOE12+ years pharma field/commercial/business operations experience with advanced degree (or 15+ with Bachelor's). Bachelor's required; advanced degree preferred. Experience leading cross-functional initiatives and driving operational excellence at scale.
1mo
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Operational Excellence Lead: BioVectra
Boston or Folsom or Philadelphia or Wilmington or Kirkland or North Carolina or Colorado or Texas or California or Durham or Cedar Creek or Frederick or Canada or Ontario or Greater Toronto Area or Canada or Prince Edward Island or Nova Scotia or New Brunswick or Charlottetown
$147k-$275k/yr FieldFull Time
10+ YOEBachelor's or master's in life science/chemical/biochemical engineering,10+ years in GMP/regulated production with microbial fermentation and downstream purification, hands-on production-system deployment experience, strong problem-solving and coaching skills.
MES, Electronic batch records, shop-floor data systems, AI
1mo
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Consultant, Operational Excellence, Manufacturing
Chicago or Boston or Parsippany or Minneapolis or St. Louis or Los Angeles or San Francisco
$105k-$120k/yr HybridFull Time
5+ YOEBachelor's in science/engineering preferred; 5+ years professional experience (minimum 5) with ≥3 years on the production floor and ≥2 years delivering manufacturing projects; strong operational excellence (Lean/Six Sigma/APICS), data analysis, project leadership, and communication skills.
1mo
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Director of Operational Excellence
Nashua, New Hampshire, United States
$153k-$261k/yr OnsiteFull Time
12+ MgmtBachelor's degree in engineering or business required; 12+ years of industrial/operations leadership in regulated or defense manufacturing; Lean Six Sigma Black Belt preferred; experience with industrial engineering, compliance (ITAR/AS9100/DFARS), and BI/dashboard development; able to obtain Secret clearance and be a U.S. person.
1d
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Sr. Manager, Supply Chain Operational Excellence
Lafayette or Mansfield or San Antonio
$145k-$217k/yr RemoteFull Time
7+ YOEBachelor's degree and 7+ years, or advanced degree and 5 years, relevant experience; Lean Six Sigma Black Belt certification; expertise in supply chain, operational excellence, transformation, coaching, and change leadership.
Medtronic Performance System (MPS)
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Director, PV Operational Excellence
Waltham, Massachusetts, United States
$200k-$245k/yr HybridFull Time
12+ YOE12+ years pharmacovigilance experience; advanced scientific degree preferred; knowledge of FDA/EMA/ICH guidance, MedDRA/WHO Drug Dictionary; experience with safety databases (Argus, ArisG, Veeva Safety); SOP/CAPA development; vendor management; Microsoft Office proficiency; travel up to 10-15%.
MedDRA, WHO Drug Dictionary, Argus, ArisG, Veeva Safety, Microsoft Word, Microsoft PowerPoint, Microsoft Excel, Microsoft Outlook, Microsoft SharePoint
1w
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Head of Operational Excellence and Enablement, Underwriting
Boston or Bethlehem or New York
$155k-$255k/yr HybridFull Time
10+ YOEBachelor's (master's preferred),10+ years in underwriting/operations,proven transformation and change leadership,experience with Lean/Six Sigma,strong analytics and stakeholder engagement skills.
2w
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Director, Data Management Operational Excellence
Cambridge, Massachusetts, United States
$167k-$301k/yr OnsiteFull Time
10+ YOEBachelor's degree required (advanced degree preferred);10+ years clinical data management experience; proven leadership in operational excellence, governance, vendor oversight, KPI/analytics, digital enablement, and GxP/regulatory inspection readiness.
1d
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Sr. Manager, Supply Chain Operational Excellence
Lafayette or Mansfield or San Antonio
$145k-$217k/yr RemoteFull Time
7+ YOEBachelor's degree with 7+ years or advanced degree with 5 years of relevant experience, plus Lean Six Sigma Black Belt certification and demonstrated continuous improvement experience.
Lean Six Sigma, Medtronic Performance System (MPS)
2w
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IPS Excellence Manager
Bedford or Burlington or United States or Darmstadt
$128k-$193k/yr HybridFull Time
5+ YOEBachelor’s degree and 5+ years in biopharma or a related industry, including 3+ years in product or portfolio management, business analysis, finance, or a related function.
Microsoft Excel, Tableau
2w
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IPS Excellence Manager
Bedford or Burlington or Darmstadt or United States
$128k-$193k/yr HybridFull Time
5+ YOEBachelor's degree and 5+ years in biopharma or a related industry, including 3+ years in product or portfolio management, business analysis, finance, or a related function.
Microsoft Excel, Tableau
3w
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Project Manager, Operational Excellence
Weymouth, Massachusetts, United States
$103k-$154k/yr OnsiteFull Time
3+ YOEBachelor's degree preferred, 3+ years project management experience preferred (healthcare strongly preferred). Requires project and change management, process improvement (LEAN,PDSA), data analysis, workflow documentation, strong communication and facilitation skills.
Microsoft Excel, Microsoft Word, Microsoft PowerPoint, Microsoft Visio, Microsoft SharePoint, Tableau, Power BI
1mo
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Manager, Process Excellence
Boston, Massachusetts, United States
$98k-$123k/yr HybridFull Time
5+ YOEBachelor's in engineering/science/technology with 5+ years (or Master's with 3+ years) in process improvement, operations, or consulting; Lean/Six Sigma experience; change management, cross-functional leadership, and continuous improvement skills.
Smartsheet, Class A / Oliver Wight Business Process Management
1w
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Process Excellence & Analytics Manager III
Salisbury or Cromwell or Quincy or Hyattsville or Scarborough or Carlisle
$121k-$209k/yr HybridFull Time
10+ YOEBachelor's degree,10+ years in process excellence/analytics or operational leadership, project and change management, Power BI proficiency, vendor and stakeholder management; Lean Six Sigma preferred.
Microsoft Power BI, Python, JavaScript, C#, Java, SQL
1w
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Process Excellence & Analytics Manager III (538771)
Salisbury or Cromwell or Quincy or Hyattsville or Scarborough or Carlisle
$121k-$209k/yr HybridFull Time
10+ YOEBachelor's degree,10+ years in process excellence/analytics or operational leadership, experience leading teams, Power BI proficiency, project management, vendor management, and ability to translate business to technical requirements.
Microsoft Power BI, Python, JavaScript, C#, Java, SQL, APIs
1w
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Process Excellence & Analytics Manager III
Carlisle or Cromwell or Hyattsville or Quincy or Salisbury or Scarborough
$121k-$209k/yr HybridFull Time
10+ YOEBachelor's degree and 10+ years in process excellence, analytics, business transformation, or operational leadership. Requires team leadership, project management, stakeholder communication, Power BI, and technical literacy.
Microsoft Power BI, Motus, Wheels, Concur, Python, JavaScript, C#, Java, SQL, APIs
1d
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Manufacturing Excellence Consultant _Manager
New York City or Indianapolis or Atlanta or Austin or Chicago or Washington or Cleveland or Columbus or Kansas City or Dallas or Baltimore or Minneapolis or Denver or Nashville or Boston or St. Louis or Philadelphia or Pittsburgh or Spartanburg or Houston
$99k-$232k/yr FieldFull Time
5+ YOEBachelor's degree and 5+ years of experience; expertise in lean manufacturing, Six Sigma, manufacturing strategy, operations, product lifecycle, cost analysis, and feasibility studies.
Six Sigma
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