280 principal data scientist jobs at 141 companies in United States

PromotedHiringCafe
Founding Machine Learning / AI Search Engineer
Cupertino, CA, US
$160k-$310k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Build the ML and AI search behind HiringCafe — ranking, recommenders, retrieval, and LLM agents that surface jobs people would never find on their own.
Python, PyTorch, Elasticsearch, LLMs
2mo
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Principal Data Scientist - Immunology - (2 positions)
Titusville or Cambridge or Raritan or Spring House or San Diego
$117k-$201k/yr HybridFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Develops and manufactures pharmaceutical drugs and medical devices.
5+ YOEPrincipal Data Scientist with bioinformatics/biomedical data expertise; 5+ years health informatics; semantic tech, ontologies, knowledge graphs; PhD or Master preferred.
Semantic Web, SPARQL, RDF, OWL, Graph Databases, Neo4j, Amazon Neptune, REST, GraphQL, Docker, CI/CD, Jenkins, GitLab, Azure DevOps, SQL, NoSQL, Proteomics, Genomics
2w
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Data Scientist / Principal Data Scientist *
Roy, Utah, United States
$87k-$162k/yr OnsiteFull Time
Northrop Grumman
Northrop GrummanNYSE: NOC: Designs and manufactures advanced aerospace and defense systems.
3+ YOEU.S. citizen able to obtain DoD Secret clearance; Bachelor's or advanced degree in STEM; 3+ years (Data Scientist) to 5+ years (Principal) experience; 2+ years cloud/data engineering; Python and SQL experience; predictive modeling and ML experience.
Python, SQL, Amazon Web Services (AWS), S3, Glue, SageMaker, Redshift, Palantir Foundry, Databricks, Snowflake
2mo
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Principal Data Scientist
United States
$162k-$259k/yr RemoteFull Time
Headspace
Headspace: Provides a digital mental health platform and meditation app.
8+ YOE6+ Mgmt8+ years analytics; 6+ years partnering with exec; 7+ years big data; 6+ years data products; 4+ years healthcare analytics; 6+ years with SQL/Python; degree in CS/stats/math.
SQL, Python, Looker, Tableau, Amplitude, Statsig, Redshift, S3, Databricks, Datalakes, Spark
2mo
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Principal Data Scientist
South San Francisco, California, United States
$174k-$217k/yr OnsiteFull Time
Structure Therapeutics
Structure TherapeuticsNASDAQ: GPCR: Developing oral small molecule medicines for chronic diseases
12+ YOE12+ years data science with production software experience; ML/DL proficiency; cloud and CI/CD; strong communication and collaboration.
Python, R, Scikit-learn, TensorFlow, PyTorch, AWS, Docker, CI/CD, GitHub
1mo
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Principal Data Scientist
Alpharetta or Irving or Basking Ridge
$121k-$231k/yr HybridFull Time
Verizon
VerizonNYSE: VZ: Provides wireless, fiber-optic internet, and telecommunications services globally.
6+ YOESix+ years of data science experience; experience with LLMs, RAG, optimization; strong SQL/Python/R; ability to influence executives.
Google BigQuery, Teradata, Python, R, SQL, Alteryx, Tableau, Claude Code, GitHub Copilot, Gurobi, Domino Data Lab, VS Code
2mo
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Principal Data Scientist
San Francisco, California, United States
$135k-$242k/yr OnsiteFull Time
Autodesk
AutodeskNASDAQ: ADSK: Developing software for architecture, engineering, and entertainment industries.
8+ YOE8+ years in data science or applied ML with product analytics experience; expertise in predictive modeling, instrumentation, and AI/ML products; strong communication.
Python, SQL, Machine Learning, LLMs, Retrieval-Augmented Generation, Vector Databases
2mo
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Principal Data Scientist
Atlanta or Greenville or Bengaluru
$139k-$231k/yr OnsiteFull Time
GE Vernova
GE VernovaNYSE: GEV: Designs and services technologies for global power generation and electrification.
10+ YOE10+ years in data science/AI with enterprise impact; strong leadership and mentorship; production-grade ML/GenAI experience; ability to drive strategy and execution.
Python, ML/AI, GenAI, EDA, Model Governance, Data Engineering Tools, SCM, Experimentation Tools
2mo
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Principal Data Scientist
Plano, Texas, United States
OnsiteFull Time
Toyota
ToyotaNYSE: TM: Designs and manufactures vehicles and provides automotive financial services.
5+ YOEMaster’s degree and 5+ years experience in data science; strong Python, PySpark, SQL; expertise in ML, DL, CV, optimization, GenAI; production deployment.
Python, PySpark, SQL, AWS SageMaker, Databricks, Spark, Airflow, GitHub
3mo
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Principal Data Scientist
Boston, Massachusetts, United States
$175k-$190k/yr OnsiteFull Time
Lutron Electronics
Lutron Electronics: Designs and manufactures lighting and shading control systems.
12+ YOEPhD or Masters in STEM; 12+ years in data science/ML/AI; leadership; Python/R/Scala; ML frameworks; cloud; MLOps; strong communication.
Python, R, Scala, ML frameworks, Cloud platforms
5d
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Principal Data Scientist
United States
RemoteFull Time
Risepoint
Risepoint: Manages online degree programs for university and college partners.
8+ YOEPrincipal-level data science leader with 8+ years in applied ML, strong Python and SQL skills, experience deploying models to production, MLOps and data engineering expertise, and cross-functional initiative ownership.
Databricks, MLFlow, dbt, Dagster, Airflow, Terraform, Docker, Kubernetes, Python, SQL, scikit-learn, XGBoost, TensorFlow, PyTorch, MLOps, CI/CD, CRM, LMS
2mo
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Principal Data Scientist
Austin or Westlake
$215k-$235k/yr OnsiteFull Time
Charles Schwab
Charles SchwabNYSE: SCHW: Financial services, brokerage, and investment management provider.
10+ YOE10+ years in data science/ML; 3+ years as senior IC; advanced degree; 8+ years Python/SQL; production ML; NLP; LLM; MLOps; roadmaps.
Python, SQL, CI/CD, MLOps, NLP, LLM
1mo
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Principal Data Scientist
Portland, Oregon, United States
HybridFull Time
Columbia Sportswear
Columbia SportswearNASDAQ: COLM: Designs and sells outdoor apparel, footwear, and active equipment.
3+ YOEBachelor’s in quantitative field required (Graduate degree preferred), 3+ years as a data scientist or similar, strong experience in predictive modeling, ML, prototyping, SQL, R/Python/SAS, Power BI, and collaboration with cross-functional teams.
SQL, R, Python, SAS, Power BI, Microsoft Stack
2w
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Principal Data Scientist
United States
$132k-$178k/yr OnsiteFull Time
RS21
RS21: Data science providing AI, analytics, and software solutions.
7+ YOE3+ MgmtMaster's (or Bachelor's + experience) in a quantitative field, 7+ years data science experience with 3+ years in a senior/principal capacity, people management experience, AWS ML platform experience, LLM/AI and production ML deployment expertise.
SageMaker, Bedrock, Redshift, Athena, EMR, Glue, Lambda, Step Functions, MLflow, SageMaker Pipelines, Jira, Databricks, Spark
2mo
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Data Scientist – Simulation (Senior - Principal)
Wilmington, Massachusetts, United States
$149k-$205k/yr HybridMultiple Commitments Available
Symbotic
SymboticNasdaq: SYM: AI-powered robotics and software for warehouse automation.
5+ YOESenior/Principal Data Scientist to lead simulation model development for robotic warehouses; 5-8 years in simulation, DES/agent-based modeling; Python and related tools.
Python, NumPy, Pandas, SciPy, SimPy, AnyLogic, Arena, Databricks, Snowflake, Grafana, Tableau, GCP, AWS, Azure, High-Performance Computing
1mo
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Principal Data Scientist - 26205
Austin, Texas, United States
RemoteFull Time
Enverus
Enverus: Software and analytics for the global energy industry.
4+ YOELead strategic data analysis and governance; drive product roadmaps; apply ML/data engineering to create customer value.
Python, SQL, Machine Learning
2mo
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Principal Data Scientist I
Raleigh, North Carolina, United States
OnsiteFull Time
LexisNexis
LexisNexisNYSE: RELX: Provides legal research and business analytics software solutions.
Leadership in analytic projects, mentorship, and senior stakeholder communication; extensive experience as a Data Scientist; experience guiding complex projects and customer relationships.
1mo
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Principal Data Scientist
Gaithersburg, Maryland, United States
$175k-$215k/yr RemoteFull Time
BullFrog AI
BullFrog AINASDAQ: BFRG: AI-powered platforms for drug discovery and clinical development.
5+ YOEAdvanced degree (MS/PhD) in a quantitative field, 5+ years post-graduate life sciences analytics experience, proficiency in Python, hands-on omics and LLM/NLP experience, strong communication and client-facing skills, U.S. work authorization required.
bfPREP™, bfLEAP™, bfARENAS™, Python, LLMs, NLP, AWS, Google Cloud
2mo
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Principal Data Scientist
Jersey City or Tampa
HybridFull Time
DTCC
DTCC: Provides post-trade infrastructure for the global financial services industry
8+ YOEMinimum 8 years of related experience; Bachelor's degree (preferred) or equivalent experience.
Python, Snowflake, Machine Learning, Data Visualization, Governance
1mo
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Principal/Senior - Data Scientist – New York City
New York City, New York, United States
HybridFull Time
Aily Labs
Aily Labs: AI-powered decision intelligence platform for large enterprises.
Senior/Lead Data Scientist with 4+ years; Principal with 6+ years; strong MLOps, Python/SQL, domain expertise; ability to lead projects and mentor teammates.
Python, SQL, MLOps, Knowledge Graph
2w
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Principal Data Scientist
United States or San Francisco or New York City
$143k-$275k/yr OnsiteFull Time
Microsoft
MicrosoftNASDAQ: MSFT: Develops software, services, devices, and cloud computing solutions.
5+ YOEAdvanced degree in quantitative field with multi-year data science experience (minimum 5+ yrs), experience managing structured/unstructured data, model evaluation, data acquisition, and strong communication skills; U.S. citizenship verification required.