85 principal researcher jobs at 27 companies in Bothell, WA

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Principal AI Researcher
Pleasanton or Atlanta or Seattle
$228k-$342k/yr HybridFull Time
Workday
WorkdayNASDAQ: WDAY: Provides cloud-based software for financial and human capital management.
8+ YOE8+ years AI/ML research; PhD or Master’s in CS/AI/Math/Physics; 4+ years DL frameworks; 2+ years LLMs/VLMs; strong publication or production impact.
PyTorch, JAX, TensorFlow
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Principal Security Researcher
Redmond, Washington, United States
$143k-$275k/yr RemoteFull Time
Microsoft
MicrosoftNASDAQ: MSFT: Develops software, services, devices, and cloud computing solutions.
4+ YOEMaster's+4 years or Bachelor's+6 years (or equivalent) in computing/security; hands-on vulnerability research, fuzzing, exploitability assessment, and tool development experience.
SARIF, C, C++, C#, Java, JavaScript, TypeScript, Python, large language models
2mo
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Principal Applied Researcher
San Jose or Seattle
$206k-$388k/yr OnsiteFull Time
Adobe
AdobeNASDAQ: ADBE: Provides software for digital media creation and marketing analytics
Masters or PhD preferred in CS or related fields; strong programming and proficiency with PyTorch, TensorFlow, or JAX; experience with transformers, diffusion/GANs, cloud/MLOps, production ML deployment, and reading/prototyping research.
PyTorch, TensorFlow, JAX, Horizon AI Stack
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Principal User Researcher, Senior Talent & Transformation: Design
Seattle, Washington, United States
$181k-$245k/yr OnsiteFull Time
Amazon
AmazonNASDAQ: AMZN: Global online retail and cloud computing technology provider.
10+ YOE10+ years UX research with executive leadership; strong research methods; advanced degree in Data Science, HCI, or related field; ability to influence senior partners.
UX research, ethnography, contextual inquiry, surveys, statistical analysis
1w
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Principal AI Security Researcher (200046441)
Redmond, Washington, United States
OnsiteFull Time
Microsoft
MicrosoftNASDAQ: MSFT: Global provider of software, cloud, and AI technology solutions.
Perform AI security research and related responsibilities as defined by the requisition.
2mo
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Principal Scientist - Cell Therapy Translational Research
Seattle, Washington, United States
$152k-$185k/yr OnsiteFull Time
Bristol Myers Squibb
Bristol Myers SquibbNew York Stock Exchange: BMY: Develops and distributes innovative medicines for serious diseases.
8+ YOELead translational research in cell therapy; develop biomarker strategies; manage CROs and collaborators; strong communication.
Flow cytometry, Transcriptomics, Proteomics, Biomarker assays, Clinical data analysis
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Senior Principal Geologist
Redmond or Portland
$126k-$175k/yr OnsiteFull Time
WSP
WSPToronto Stock Exchange: WSP: Provides engineering, design, and environmental consultancy services globally.
12+ YOEB.S. in geology or related field, 12+ years environmental consulting experience, licensed LHG or PG, expertise with MTCA/CERCLA/RCRA, strong technical writing and client management skills.
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Associate Principal - Data Sciences
Seattle, Washington, United States
$105k-$173k/yr OnsiteFull Time
LTIMindtree
LTIMindtreeNational Stock Exchange of India: LTIM: Global technology consulting and digital solutions.
12+ YOE12–18 years of experience designing GenAI multimodal pipelines, prompt engineering, LLM inference, Python programming, JSON generation, data pipelines, and AWS services including Bedrock, Lambda, S3, and Kinesis.
AI, Generative AI, AWS Bedrock, Claude, Nova, Amazon Bedrock, AWS Lambda, Amazon S3, Amazon Kinesis, Python, JSON
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Principal Scientist - Cell Therapy Translational Research
Seattle, Washington, United States
$152k-$185k/yr OnsiteFull Time
Bristol Myers Squibb
Bristol Myers SquibbNYSE: BMY: Develops and manufactures innovative prescription biopharmaceutical medicines.
4+ YOEAdvanced degree in life sciences (BS/MS/PhD) with 4–8+ years industry or academic experience; expertise in immunology/cell therapy, biomarker assays (flow cytometry, transcriptomics, proteomics), data analysis, translational strategy, CRO oversight, and regulatory writing.
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Principal Experimental Scientist - RF
Everett, Washington, United States
$230k-$270k/yr OnsiteFull Time
Helion
Helion: Building fusion reactors to produce clean, low-cost electricity.
10+ YOEPhD in physics, plasma physics, electrical engineering, or related field; 10+ years in lab/R&D with plasma systems; expertise in RF plasma sources and diagnostics.
RF hardware, Antenna design, Vacuum systems, Plasma diagnostics, RF-plasma interactions
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Archaeologist Principal Investigator /Field Director
Portland or Seattle or Eugene or Medford or Bend
$75k-$105k/bi-wk FieldFull Time
True Environmental
True Environmental: Diversified provider of environmental consulting and engineering services.
5+ YOE5+ MgmtMaster's in archaeology/anthropology, RPA, ability to hold state archaeology permits, 5+ years supervisory cultural resources experience, MS Office proficiency, valid driver's license, ability to pass drug/alcohol tests.
Microsoft Office
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Principal Technical Consultant, Archaeologist - Oregon or Washington
Seattle or Portland
$106k-$145k/yr HybridFull Time
ERM: Global consultancy providing environmental, health, safety, and sustainability services.
10+ YOESenior archaeologist with 10+ years experience; PI eligibility in PNW; RPA; travel; strong NEPA/SEPA knowledge.
GPS, ArcGIS Field Maps, Survey123, Total Station
1w
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Principal AI/ML Research Engineer
United States or California or San Jose or Seattle or Portland or Boston or Chicago
$250k-$289k/yr RemoteFull Time
WEX
WEXNYSE: WEX: Provides global payment processing and business information management services.
12+ YOE12+ years in software or ML engineering, including 5+ years in applied AI/ML research. Requires advanced expertise in model architecture, algorithms, Python, deep learning frameworks, distributed AI, cloud, and ML platforms.
Python, PyTorch, TensorFlow, JAX, C++, Java, Ray, DeepSpeed, Megatron, Spark, AWS, Azure, SageMaker, MLflow, Databricks, LanceDB, Pinecone, Qdrant, Milvus, Transformer, Tabular Transformers, LLMs, RAG, LoRA, PEFT, Diffusion, Reinforcement Learning, RLHF, NeurIPS, ICML, KDD, ACL
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Principal Applied Scientist- AI
Bellevue, Washington, United States
$218k-$265k/yr OnsiteFull Time
UiPath
UiPathNYSE: PATH: Provides robotic process automation software for enterprise workflow automation.
Deep expertise in frontier AI, large language or multimodal models, production ML systems, Python, PyTorch, distributed training, and end-to-end research-to-production deployment; PhD or equivalent experience preferred.
Python, PyTorch, JAX, CUDA, vLLM, Ray, DeepSpeed, FSDP, Triton, LangGraph, Semantic Kernel, MCP, Kubernetes, Azure AI, Hugging Face, RAG, DPO, PPO, GRPO, RLHF
3w
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Principal, Quality Assurance
Bothell, Washington, United States
$150k-$185k/yr OnsiteFull Time
Lyell Immunopharma
Lyell ImmunopharmaNASDAQ: LYEL: Developing next-generation T-cell therapies for patients with solid tumors.
5+ YOEExperience in cGMP clinical manufacturing, electronic quality management systems, process validation for plasmid/LVV preferred, 5+ years in Quality Assurance, regulatory submission and inspection readiness experience.
1mo
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Principal Scientist, Immunology
San Francisco or Seattle
$175k-$190k/yr RemoteFull Time
Jade Biosciences
Jade BiosciencesNASDAQ: JBIO: Developing best-in-class therapies for autoimmune diseases.
8+ YOEPhD in immunology or related field with 8+ years industry experience; deep immunology expertise, drug development knowledge, experience with immunological assays (flow cytometry, ELISA/MSD), strong communication and publication record.
flow cytometry, ELISA/MSD, cytokine panels, cellular assays, single-cell, proteomics
4w
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AI Engineer - Principal
Bellevue, Washington, United States
$154k-$278k/yr HybridFull Time
Siemens
SiemensXETRA: SIE: Manufactures industrial automation, infrastructure, and energy technology systems.
Experience designing and implementing AI-driven automation with Siemens CAD/CAM tools, LLM-based workflows, and integrating AI into engineering software; ability to interface with customers and lead technical teams.
Siemens CAD/CAM tools, LLM
2mo
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Senior/Principal Fisheries Scientist
Wenatchee or Seattle or Portland or Washington or Oregon or Idaho or California or Montana
$110k-$145k/yr RemoteFull Time
Spheros Environmental
Spheros Environmental: Environmental consulting firm providing integrated science-based sustainability solutions.
10+ YOEBachelor's in fisheries science/biology/ecology required (Masters/Doctorate preferred); 10+ years experience in Pacific Northwest salmonid issues; expertise in fish passage, ESA consultation, hatchery operations, study design, quantitative analysis, project management, and staff supervision; valid driver’s license.
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Principal Research Scientist, Siri Innovation Studio
Seattle, Washington, United States
OnsiteFull Time
Apple
AppleNASDAQ: AAPL: Designs and sells consumer electronics, software, and online services.
Expertise in machine learning modeling, incubating and deploying ML-driven features, collaborating across software/hardware/design teams, and building user-centered AI for assistants and speech products.
iOS, iPadOS, macOS, watchOS, visionOS
3w
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Principal UI/UX Designer
San Francisco or Seattle or Bellevue
$197k-$314k/yr HybridFull Time
Salesforce
SalesforceNYSE: CRM: Sells cloud-based customer relationship management and business software solutions.
10+ YOE10+ years designing enterprise products, deep knowledge of design systems, AI/product design, user research, and mentorship. Portfolio and samples required.
Figma, Figma Make, Claude, Cursor, Salesforce Design System (SLDS2)