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25 principal scientist jobs at 12 companies in Carson, CA

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Senior Principal Scientist
Thousand Oaks, California, United States
$168k-$228k/yr HybridFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
Doctorate or equivalent scientific degree with toxicology experience; expertise in leachables/extractables, risk-based toxicology assessments, OEL/OEB derivation, GHS classification, and regulatory guidance (ICH/ISO).
OECD Toolbox, Toxtree, Benchmark Dose (BMD), EndNote, Microsoft Office
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3w
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Associate Principal Scientist, Innovation
El Segundo, California, United States
$116k-$174k/yr HybridFull Time
Liquid I.V.
Liquid I.V.NYSE: UL: Sells electrolyte drink mixes to improve hydration efficiency.
6+ YOEMaster's in nutrition/exercise physiology or related,6+ years R&D/innovation experience in CPG or supplements,expertise with dietary supplement ingredients,supporting concept-to-commercialization,AI tools and cross-functional work.
Microsoft Office, Citation Managers, PubMed, AI tools and platforms
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2w
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Principal Clinical Scientist
Aliso Viejo, California, United States
$148k-$194k/yr OnsiteFull Time
MicroVention
MicroVention: Manufacturer of neurovascular medical devices for stroke treatment.
5+ YOEMaster's degree in relevant science/medicine, 5+ years clinical research scientist experience, GCP knowledge, clinical protocol development, strong writing and communication, analytical skills.
PubMed, MedLine
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1mo
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Principal Scientist- Search
New York City or San Francisco or Los Angeles or Irvine or McLean or Washington
$212k-$394k/yr HybridFull Time
Thomson Reuters
Thomson ReutersNASDAQ: TRI: Provides professional software, data, and news services globally.
8+ YOEPhD and 8+ years building and deploying production AI systems; deep expertise in information retrieval, search, NLP, RAG, knowledge graphs, LLMs; strong product sense and leadership skills.
Python, PyTorch, Hugging Face, Azure ML, Azure AI Foundry, AWS SageMaker
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2w
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Principal Data Scientist - Games
Glendale, California, United States
$156k-$209k/yr OnsiteFull Time
The Walt Disney Company
The Walt Disney CompanyNYSE: DIS: Produces media content and operates global theme parks.
10+ YOE10+ years data science experience; advanced analytics, experimentation, forecasting, and behavioral segmentation for games/telemetry; strong SQL and Python/R skills; executive communication and cross-functional influence.
SQL, Python, R, Snowflake, Databricks, AWS, Tableau, Looker
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Principal Data Scientist - Games
Glendale, California, United States
$156k-$209k/yr OnsiteFull Time
The Walt Disney Company
The Walt Disney CompanyNYSE: DIS: Produces movies, operates theme parks, and provides streaming services.
10+ YOEBachelor's in quantitative field,10+ years data science experience in gaming/entertainment,proficiency in SQL and Python or R,experience with cloud analytics and experimentation,strong communication and storytelling skills.
SQL, Python, R, Snowflake, Databricks, AWS, Tableau, Looker
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2w
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Principal Data Scientist, Pricing
Los Angeles, California, United States
RemoteFull Time
UP.Labs
UP.Labs: Builds and scales mobility-focused startups with corporate partners.
8+ YOE8+ years in data science with pricing/revenue optimization experience; production ML deployment experience; strong quantitative modeling; ability to communicate with product and executive stakeholders.
Python, SQL, AWS, GCP, Azure, Snowflake, Databricks, dbt
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Principal Clinical Research Scientist
Jacksonville or Milpitas or Irvine
$117k-$201k/yr HybridFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Develops and manufactures pharmaceutical drugs and medical devices.
5+ YOEAdvanced scientific degree and 5+ years of ophthalmic clinical research experience required, with clinical study leadership, study design, technical writing, biostatistics knowledge, and cross-functional influence.
Clinical Study Reports (CSRs), Good Clinical Practice (GCP)
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Principal Clinical Research Scientist
Jacksonville or Milpitas or Irvine
$117k-$201k/yr HybridFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Provides pharmaceutical products and medical technology healthcare solutions.
5+ YOEAdvanced scientific degree, 5+ years of ophthalmic clinical research experience, clinical program leadership, study design, technical writing, biostatistics knowledge, and cross-functional influence.
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Senior Principal Data Scientist, AEC
California or Washington or New York or British Columbia or Ontario or Irvine
$159k-$286k/yr RemoteFull Time
Autodesk
AutodeskNASDAQ: ADSK: Developing software for architecture, engineering, and entertainment industries.
10+ YOE10+ years in data science/applied ML focused on product analytics and user behavior modeling; expertise in predictive modeling, instrumentation, AI evaluation, and experimentation; strong communication and technical leadership.
LLMs, MCP, RAG architectures, LLM-as-a-Judge, A/B testing
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Principal Applied Scientist Perception, Compass
Pasadena, California, United States
$199k-$269k/yr OnsiteFull Time
Amazon
AmazonNASDAQ: AMZN: Global online retail and cloud computing technology provider.
6+ YOEPhD in a technical field, 6+ years in perception research (robotics preferred), strong publication record, experience deploying perception on robots, and proficiency in Python and C++.
Python, C++, LiDAR, depth cameras, radar, embedded GPUs
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8h
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Data Scientist, Principal - AI Product Engineering
Oakland or Washington or Ohio or District of Columbia or California or Long Beach or Arizona or Colorado or Connecticut or Florida or Georgia or Maryland or Minnesota or Nevada or Oregon or El Dorado Hills or San Diego or Woodland Hills or Alabama or Illinois or Virginia or Wisconsin or Texas or New York
$161k-$242k/yr HybridFull Time
Ascendiun
Ascendiun: Nonprofit parent overseeing health insurance and clinical service organizations.
10+ YOEBachelor's degree or equivalent practical experience and 10 years in data science, machine learning, AI/ML, software engineering, or advanced analytics. Requires Python, APIs, ML infrastructure, PyTorch, TensorFlow, LangChain, and LangGraph.
Python, PyTorch, TensorFlow, LangChain, LangGraph, Azure, Google Cloud, AWS, SQL, Spark, CI/CD, MLOps, LLMOps
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Principal Research Scientist - Frontier Industrial AI
San Leandro or New York City or Massachusetts or Lake Forest or Philadelphia
$214k-$356k/yr HybridFull Time
AVEVA
AVEVA: Industrial software for engineering and operational performance management.
PhD or equivalent research experience in a relevant field; original AI research, strong software development, experimental systems, independent project execution, and expertise in advanced machine learning areas.
Python
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2027 Principal Research Scientist - Directed Energy and Thermal Physics - Manhattan Beach CA
Manhattan Beach, California, United States
$114k-$171k/yr OnsiteFull Time
Northrop Grumman
Northrop GrummanNYSE: NOC: Develops and manufactures advanced aerospace, defense, and space systems.
Completing or completed a PhD in applied physics, materials science, electrical engineering, thermal physics, or related field; U.S. citizenship and eligibility for government clearance required.
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2027 Principal Research Scientist - Directed Energy and Thermal Physics - Manhattan Beach CA
Manhattan Beach, California, United States
$114k-$171k/yr OnsiteFull Time
Northrop Grumman
Northrop GrummanNYSE: NOC: Designs and manufactures advanced aerospace and defense systems.
Completing or completed a PhD in applied physics, materials science, electrical engineering, thermal physics, or related field; U.S. citizenship and eligibility for government clearance required.
laser systems, cleanroom
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