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42 principal scientist jobs at 10 companies in Chicago, IL

3w
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Principal Scientist
Wood Dale, Illinois, United States
OnsiteFull Time
Chem-Impex
Chem-Impex: Manufacturing and distributing laboratory chemicals for life science research.
Advanced degree (PhD or MS) in Chemistry/Biochemistry, hands-on peptide synthesis and SPPS experience, ability to translate technical insight into commercial products, presentation and customer engagement experience, willingness to travel.
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3mo
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Principal Scientist
Melrose Park, Illinois, United States
$80k-$95k/yr OnsiteFull Time
Fresenius Kabi
Fresenius Kabi: Provides lifesaving medicines and technologies for clinical care.
7+ YOELead and manage E&L team; design, execute and regulatory-approve E&L studies; collaborate cross-functionally; ensure cGMP compliance and regulatory readiness.
GC/MS, HR-LC/MS, ICP-MS, Soxhlet extraction, ASE, Mass spectrometry
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2w
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Principal Data Scientist
Mettawa, Illinois, United States
$125k-$237k/yr HybridFull Time
AbbVie
AbbVieNYSE: ABBV: Develops and sells innovative pharmaceutical and biopharmaceutical medicines.
8+ YOE8+ years data science experience with production ML, 5+ years pharma commercial analytics preferred; strong Python/R, SQL, ML lifecycle, causal inference, and cross-team collaboration.
Python, R, SQL, pandas, NumPy, scikit-learn, PySpark, PyTorch, TensorFlow, Azure ML, Databricks, MLflow
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1mo
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Principal Scientist – Data Insights & Hypothesis Design
Chicago or Redwood City or New York City or California or New York
$150k-$200k/yr HybridFull Time
Tempus AI
Tempus AINASDAQ: TEM: Builds a data platform for AI-powered precision medicine diagnostics.
6+ YOEPhD in NGS-related field,6+ years industry experience,domain expertise in oncology/neurology/immunology,large-scale clinico-genomic analysis,SQL/Python/R proficiency,and experience translating data into production products.
SQL, R, Python, Tempus Data Model (TDM)
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2w
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Principal Scientist, R&D – Consumer Experience (CX) Product Insights​
Glenview, Illinois, United States
$104k-$130k/yr HybridFull Time
Kraft Heinz
Kraft HeinzNASDAQ: KHC: Manufacturer and global marketer of food and beverage products.
6+ YOEBachelor's degree, 6+ years consumer/product research experience (CPG preferred); expertise in qualitative and quantitative CX methods, study design, analysis, synthesis, stakeholder communication, and coaching.
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2w
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Principal Scientist, R&D – Consumer Experience Packaging Research SME
Glenview, Illinois, United States
$104k-$130k/yr HybridFull Time
Kraft Heinz
Kraft HeinzNASDAQ: KHC: Produces and sells condiments, dairy products, and packaged foods.
6+ YOEBachelor's degree in relevant field required (advanced degree preferred); 6+ years' experience in consumer/product research or CX; expertise in qualitative/quantitative methods; packaging research experience; strong communication and coaching skills.
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5d
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Principal Data Scientist
Amelia or Cary or Evansville or Chillicothe or Chesapeake or Durham or Berea or Columbus or Clarksville or Boca Raton or Indianapolis or Buffalo or Charleston or Dayton or Athens or Knoxville or Clearwater or Chicago or Arlington or Cleveland or Gaylord or Carmel or Ann Arbor or Bloomington or Cincinnati or Bremen or Charlotte or Circleville or Birmingham or Chattanooga
HybridFull Time
Munich Re
Munich ReFrankfurt Stock Exchange: MUV2: Global provider of reinsurance, insurance, and risk management solutions.
6+ YOEFCAS and a master's degree required; 6+ years of insurance data science or 8+ years of predictive modeling experience. Requires R, Python, GLMs, GBMs, machine learning, and project management.
R, Python, Databricks, Scrum, Kanban, Microsoft Excel
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1w
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Principal Data Scientist - FDE
United States or Redmond or Mountain View or Austin or Houston or Chicago or Cambridge or New York City or Atlanta
$143k-$275k/yr RemoteFull Time
Microsoft
MicrosoftNASDAQ: MSFT: Develops software, services, devices, and cloud computing solutions.
3+ YOERequires a doctorate and 3+ years, master's and 5+ years, or bachelor's and 7+ years in data science or a related field; customer-facing delivery experience preferred and travel up to 25%.
AI
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2d
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Principal Decision Scientist, Strategy & Innovation
New York or Chicago or New York City
$144k-$288k/yr RemoteFull Time
CVS Health
CVS HealthNYSE: CVS: Provides retail pharmacy, health insurance, and pharmacy benefit management services.
10+ YOE10+ years in quantitative, decision, or data science; expert SQL, Python, statistics, and causal inference; healthcare payer data experience; executive presentation skills; bachelor's degree in a quantitative field.
SQL, Python, Snowflake, GCP, AWS, Azure, R, Ruby, Scala, C++, NoSQL, ETL
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2mo
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Senior/Principal Engineer or Scientist, Combination Products
Bern or Munich or Switzerland or Research Triangle Park or Boston or Chicago or Philadelphia or New Jersey
HybridFull Time
Kymanox
Kymanox: Provides integrated engineering and regulatory services for life sciences.
8+ YOEMinimum 8+ years in medical device, pharmaceutical, or combination product industries, bachelor's in engineering or science required, subject matter expertise in combination products, technical leadership and client-facing experience.
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1mo
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Principal Associate, Data Scientist - Global Payments Network: Data Solutions and Modeling
Chicago, Illinois, United States
$147k-$168k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: Provides credit card, banking, and auto loan services.
3+ YOEBachelor's degree plus 5 years, master's or quantitative MBA plus 3 years, or PhD in a quantitative field; experience with data analytics, machine learning, SQL, and Python, Scala, or R.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL, Large Language Models (LLMs)
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1mo
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Principal Associate, Data Scientist - Global Payments Network: Data Solutions and Modeling
Chicago, Illinois, United States
$147k-$168k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: A diversified financial services providing banking and credit products.
5+ YOEQuantitative bachelor's degree plus 5 years, master's or quantitative MBA plus 3 years, or PhD. Preferred: 3+ years in Python, Scala, or R, machine learning, and SQL; LLM and AI agent experience.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL, Large Language Models (LLMs)
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2mo
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Principal Associate, Data Science - Model Risk Office
McLean or Chicago or New York City or Plano
$162k-$185k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: Financial services offering credit cards, banking, and loans.
3+ YOEDegree in a quantitative field (BS+5yrs, MS+3yrs, or PhD) with 3+ years data analytics experience typical; strong skills in Python, Spark, SQL, AWS, model validation, machine learning, and leadership.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL
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