10 principal scientist jobs at 9 companies in Colorado
3w
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Sr. Principal Scientist
Denver, Colorado, United States
$145k-$170k/yr OnsiteFull Time
15+ YOEMaster's degree in food, grain, cereal, chemistry, or engineering field and 15+ years of industry experience; expertise in grain science, milling, baking, ingredients, DOE, commercialization, and scientific leadership.
Electronic Medical Records (EMR), Microsoft Excel, Mixograph, Farinograph, Extensograph, Alveograph, RVA, Texture Analyzer, Six Sigma
2mo
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Principal Scientist
Thornton, Colorado, United States
$130k-$170k/yr OnsiteFull Time
10+ YOEPh.D. in a related field, 10+ years industry/applied research experience in semiconductor technologies, deep expertise in vacuum systems and thin-film deposition (ALD, CVD), R&D program leadership, project management, and hands-on cleanroom laboratory practice.
ALDx, ALD, CVD, vacuum systems, TEPHRA, PPE, OSHA
3mo
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Senior Principal Scientist - Bioanalytical Research
Louisville, Colorado, United States
$71k-$213k/yr OnsiteFull Time
5+ YOEBachelor's +7 yrs or Master's +5 yrs in a science/engineering field; experience with LC-MS/MS, ICP, QQQ, HRMS, bioanalysis and ADME; sample prep and instrument troubleshooting; authorized to work in the US (no visa sponsorship).
LC-MS/MS, inductively coupled plasma (ICP), triple quadrupole (QQQ), high-resolution mass spectrometer (HRMS), QToF, Orbitrap, Agilent 8900 ICP-MS, Sciex 6500/7500, Thermofisher Orbitrap Exploris 240/480/Tribrid, Mass Hunter, Biopharma Finder, QuantBrowser, MultiQuant, Biologics Explorer, Protein Metrics, MassMetaSite, eLN, signals, benchling, Phoenix, Watson LIMS, R-studio aNCA, PRISM, BioRender, Apricot, Hamilton, Tecan, KingFisher
3w
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Principal Data Scientist
North Carolina or Mississippi or Louisiana or South Carolina or Kentucky or Kansas or Iowa or Indiana or Arkansas or Texas or Durham or Georgia or Virginia or Tennessee or Pennsylvania or Michigan or Wyoming or Wisconsin or Idaho or Utah or Florida or South Dakota or Oklahoma or Ohio or Arizona or Missouri or Alabama or Colorado or Maryland
$144k-$230k/yr RemoteFull Time
8+ YOEBachelor's or advanced degree and 8+ years of related experience, or 10+ years without a degree. Requires advanced data science, healthcare, Payment Integrity/FWA, Snowflake, Python, R, SQL, and AI agent experience.
Snowflake, Python, R, SQL, Big Data, Machine Learning (ML)
2w
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Principal Machine Learning Scientist
Colorado or Irmo or Alabama or Miami or Georgia or North Carolina or South Carolina or Germantown or Columbia
$118-$126/hr RemoteFull Time
7+ YOEMaster’s degree or equivalent advanced experience; 7+ years in applied data science, statistical modeling, machine learning, or quantitative research; advanced Python and SQL; experience with production solutions and large datasets.
Python, SQL, Pandas, NumPy, SciPy, Jupyter Notebooks, dbt, Dagster, Apache Flink, ClickHouse, PostgreSQL, Apache Iceberg, Git, GitHub, Docker, MLflow
1mo
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Principal Scientist, Adsorbent Chemistry
Boulder, Colorado, United States
$125k-$150k/yr OnsiteFull Time
5+ YOEPh.D. (5+ years) or M.S. (8+ years) in chemistry/materials/chemical engineering, expertise in resin activation and functionalization, process development and scale-up, experimental design, cross-functional collaboration; U.S. citizenship required.
DOE, statistical process control, process modeling tools
2w
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Principal Machine Learning Scientist
Colorado or Irmo or Alabama or Miami or Georgia or North Carolina or South Carolina or Germantown or United States
RemoteFull Time
7+ YOEMaster’s degree or equivalent advanced experience, 7+ years in applied data science or quantitative research, advanced Python and SQL, statistical modeling, production deployment, and large or time-series datasets.
Python, SQL, Pandas, NumPy, SciPy, Jupyter Notebooks, dbt, Dagster, Apache Flink, ClickHouse, PostgreSQL, Apache Iceberg, Git, GitHub, Docker, MLflow
2w
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Data Scientist, Principal - AI Product Engineering
Oakland or Washington or Ohio or District of Columbia or California or Long Beach or Arizona or Colorado or Connecticut or Florida or Georgia or Maryland or Minnesota or Nevada or Oregon or El Dorado Hills or San Diego or Woodland Hills or Alabama or Illinois or Virginia or Wisconsin or Texas or New York
$161k-$242k/yr HybridFull Time
10+ YOEBachelor's degree or equivalent practical experience and 10 years in data science, machine learning, AI/ML, software engineering, or advanced analytics. Requires Python, APIs, ML infrastructure, PyTorch, TensorFlow, LangChain, and LangGraph.
Python, PyTorch, TensorFlow, LangChain, LangGraph, Azure, Google Cloud, AWS, SQL, Spark, CI/CD, MLOps, LLMOps
2mo
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Principal Scientist, Upstream Process Science
Louisville, Colorado, United States
$150k-$165k/yr OnsiteFull Time
6+ YOEPh.D.+6 yrs or M.Sc.+9 yrs or B.S.+12 yrs in life sciences with extensive upstream biopharma process development/GMP manufacturing experience; method development/validation and DOE expertise; supervisory experience preferred.
5d
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Principal Data Scientist Engineer (TS/SCI with CI Poly Required)
Aurora, Colorado, United States
$230k-$255k/yr OnsiteFull Time
15+ YOE4+ MgmtRequires 15+ years related experience, TS/SCI with polygraph, and a PhD in a related engineering discipline or qualifying master's degree with 20 years' experience. Requires enterprise AI/ML leadership and data science expertise.
TensorFlow, PyTorch, MLflow, AWS SageMaker, Airflow, PostgreSQL, MongoDB, NiFi, Kafka, Docker, Kubernetes, Kubeflow