19 principal scientist jobs at 11 companies in Compton, CA

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Associate Principal Scientist, Innovation
El Segundo, California, United States
$116k-$174k/yr HybridFull Time
Liquid I.V.
Liquid I.V.NYSE: UL: Sells electrolyte drink mixes to improve hydration efficiency.
6+ YOEMaster's in nutrition/exercise physiology or related,6+ years R&D/innovation experience in CPG or supplements,expertise with dietary supplement ingredients,supporting concept-to-commercialization,AI tools and cross-functional work.
Microsoft Office, Citation Managers, PubMed, AI tools and platforms
6d
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Principal Clinical Scientist
Aliso Viejo, California, United States
$148k-$194k/yr OnsiteFull Time
MicroVention
MicroVention: Manufacturer of neurovascular medical devices for stroke treatment.
5+ YOEMaster's degree in relevant science/medicine, 5+ years clinical research scientist experience, GCP knowledge, clinical protocol development, strong writing and communication, analytical skills.
PubMed, MedLine
2w
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Principal Scientist- Search
New York City or San Francisco or Los Angeles or Irvine or McLean or Washington
$212k-$394k/yr HybridFull Time
Thomson Reuters
Thomson ReutersNASDAQ: TRI: Provides professional software, data, and news services globally.
8+ YOEPhD and 8+ years building and deploying production AI systems; deep expertise in information retrieval, search, NLP, RAG, knowledge graphs, LLMs; strong product sense and leadership skills.
Python, PyTorch, Hugging Face, Azure ML, Azure AI Foundry, AWS SageMaker
3w
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Senior Principal Data Scientist, Advanced Forecasting
Irvine, California, United States
$145k-$205k/yr OnsiteFull Time
Edwards Lifesciences
Edwards LifesciencesNYSE: EW: Designs and manufactures medical devices for structural heart disease.
10+ YOEBachelor's degree in quantitative field, minimum 10 years experience (or 8 with Masters/4 with PhD), strong statistical and ML fundamentals, hands-on Python/R and SQL, forecasting and scenario modeling experience, excellent communication.
Python, R, SQL, Anaplan, Oracle, JDE, Concur, Salesforce.com, Databricks, Azure, AWS
2w
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Data Scientist, Principal
Oakland or Washington or Ohio or District of Columbia or California or Long Beach or Arizona or Colorado or Connecticut or Florida or Georgia or Maryland or Minnesota or Nevada or Oregon or El Dorado Hills or San Diego or Woodland Hills or Alabama or Illinois or Virginia or Wisconsin or Texas or New York
$182k-$273k/yr HybridFull Time
Ascendiun
Ascendiun: Nonprofit parent overseeing health insurance and clinical service organizations.
8+ YOEAdvanced experience in applied AI/ML and software development, strong Python engineering, hands-on with deep learning and LLM frameworks, experience building production AI applications and leading ML design.
Python, PyTorch, TensorFlow, LangChain, LangGraph, SQL, Spark, Azure, Google Cloud, AWS
1w
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Principal Scientist - Modeling & Simulation
Thousand Oaks, California, United States
$144k-$194k/yr OnsiteFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
2+ YOEPhD (2 yrs) or MS (5 yrs) or BS (7 yrs) experience in PK/PD or statistical modeling; proficiency with modeling software; strong quantitative and communication skills.
NONMEM, SAS, R/S-Plus, STAN, MATLAB
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Principal Data Scientist - Games
Glendale, California, United States
$156k-$209k/yr OnsiteFull Time
The Walt Disney Company
The Walt Disney CompanyNYSE: DIS: Produces movies, operates theme parks, and provides streaming services.
10+ YOEBachelor's in quantitative field,10+ years data science experience in gaming/entertainment,proficiency in SQL and Python or R,experience with cloud analytics and experimentation,strong communication and storytelling skills.
SQL, Python, R, Snowflake, Databricks, AWS, Tableau, Looker
6d
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Principal Data Scientist - Games
Glendale, California, United States
$156k-$209k/yr OnsiteFull Time
The Walt Disney Company
The Walt Disney CompanyNYSE: DIS: Produces media content and operates global theme parks.
10+ YOE10+ years data science experience; advanced analytics, experimentation, forecasting, and behavioral segmentation for games/telemetry; strong SQL and Python/R skills; executive communication and cross-functional influence.
SQL, Python, R, Snowflake, Databricks, AWS, Tableau, Looker
1w
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Principal Data Scientist, Pricing
Los Angeles, California, United States
RemoteFull Time
UP.Labs
UP.Labs: Builds and scales mobility-focused startups with corporate partners.
8+ YOE8+ years in data science with pricing/revenue optimization experience; production ML deployment experience; strong quantitative modeling; ability to communicate with product and executive stakeholders.
Python, SQL, AWS, GCP, Azure, Snowflake, Databricks, dbt
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Process Development Principal Scientist
Thousand Oaks, California, United States
$142k-$192k/yr OnsiteFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
5+ YOEPhD/PharmD/MD or advanced degree with significant operations experience; deep expertise in organic/physical/solid-state chemistry, formulation and unit operations; experience mentoring, technical writing, and characterization techniques.
XRPD, DSC, TGA, SEM
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Process Development Principal Scientist
Thousand Oaks, California, United States
$142k-$192k/yr OnsiteFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
2+ YOEAdvanced scientific degree with relevant industry experience; expertise in analytical characterization (CE, SEC, IEX, RP, HILIC, mass spectrometry, XRPD, DSC, TGA, SEM); experience authoring regulatory documents and leading analytical strategy.
CE, SEC, IEX, RP, HILIC, mass spectrometry, XRPD, DSC, TGA, SEM
1mo
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Senior Principal Data Scientist, AEC
California or Washington or New York or British Columbia or Ontario or Irvine
$159k-$286k/yr RemoteFull Time
Autodesk
AutodeskNASDAQ: ADSK: Developing software for architecture, engineering, and entertainment industries.
10+ YOE10+ years in data science/applied ML focused on product analytics and user behavior modeling; expertise in predictive modeling, instrumentation, AI evaluation, and experimentation; strong communication and technical leadership.
LLMs, MCP, RAG architectures, LLM-as-a-Judge, A/B testing
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Principal Applied Scientist Perception, Compass
Pasadena, California, United States
$199k-$269k/yr OnsiteFull Time
Amazon
AmazonNASDAQ: AMZN: Global online retail and cloud computing technology provider.
6+ YOEPhD in a technical field, 6+ years in perception research (robotics preferred), strong publication record, experience deploying perception on robots, and proficiency in Python and C++.
Python, C++, LiDAR, depth cameras, radar, embedded GPUs
3w
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Principal Scientist – Surface Biology Early Validation Lead
Thousand Oaks, California, United States
$140k-$190k/yr OnsiteFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
3+ MgmtAdvanced scientific degree or equivalent experience with demonstrated leadership; minimum 3 years people-management experience; expertise in cell-surface biology and quantitative cell-based assays; experience with flow cytometry, microscopy, imaging, and proteomics.
flow cytometry, microscopy, high-content imaging, proteomics
1w
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Process Development Sr Principal Scientist
Thousand Oaks, California, United States
$158k-$213k/yr OnsiteFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
3+ YOEDoctorate (or equivalent) or advanced degree with scientific experience; experience in analytical method development, oligonucleotide/peptide/small molecule characterization, MS/NMR/FTIR techniques, GLP/GMP familiarity, technical writing, and cross-functional leadership.
MS, UV, NMR, FTIR
3mo
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Process Development Sr Principal Scientist
Thousand Oaks, California, United States
$158k-$213k/yr HybridFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
3+ YOEDoctorate/PharmD/MD with 3+ years; or Master with 6+ years; or Bachelor with 8+ years in scientific fields.
Process engineering, Statistical analysis, Data analysis, Laboratory information systems
1w
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Principal Scientist - Clinical Pharmacology Modeling and Simulation
Thousand Oaks, California, United States
$148k-$200k/yr HybridFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
2+ YOEAdvanced degree in relevant quantitative discipline with 2–7 years clinical pharmacology/pharmacometrics/modeling and simulation experience; expertise in population PK/PD, PBPK, exposure-response, and regulatory submissions.
3d
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Principal Scientist – Chemical Biology & Proximity-Based Therapeutics
Thousand Oaks, California, United States
$140k-$190k/yr OnsiteFull Time
Amgen
AmgenNASDAQ: AMGN: Develops and manufactures biotechnology medicines for serious diseases.
2+ YOEPhD/MS/BS in chemical biology or related field with industry experience (2–7 years depending on degree), expertise in chemical biology, phenotypic screening, and mechanism-of-action studies.
1w
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Communication & Network Architect - Principal Scientist/Engineer
El Segundo, California, United States
$204k-$306k/yr OnsiteFull Time
The Aerospace Corporation
The Aerospace Corporation: Provides technical expertise and research for national space programs.
15+ YOEBachelor's in STEM,15+ years in communications and space/ground network architecture, experience with SATCOM, pLEO, optical crosslinks, AI/ML, prototyping, mentoring; ability to attain Top Secret/SCI and U.S. citizenship required.
AI/ML, SATCOM, pLEO, optical crosslinks