10 principal scientist jobs at 7 companies in Hamden, CT

3mo
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Principal Scientist – Antibody Discovery/Protein Design
Branford, Connecticut, United States
OnsiteFull Time
EvolveImmune Therapeutics
EvolveImmune Therapeutics: Developing next-generation T cell engagers for cancer immunotherapy.
5+ YOEPhD in biochemistry, computational biology, or structural biology with 5+ years antibody/biotherapeutic engineering experience; AI/ML protein design; antibody display tech; multispecific protein design; strong cross-functional collaboration.
AI/ML, Yeast display, Phage display, Antibody engineering, Biophysical characterization, Multispecific protein design
2mo
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Principal Engineer/Scientist - MA Licensed Site Professional
Wakefield or Boston or Braintree or Clifton Park or Manchester or Middletown or Portland or Springfield
$131k-$223k/yr HybridFull Time
Arcadis
ArcadisEuronext Amsterdam: ARCAD: Designing and engineering sustainable solutions for natural and built environments
15+ YOEMassachusetts Licensed Site Professional; 15+ years environmental consulting; BS in Engineering/Geology/Hydrogeology; Massachusetts market experience; active LSP certification.
2w
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Principal Scientist - Advanced Technology
Melville, New York, United States
$115k-$125k/yr OnsiteFull Time
The Estée Lauder Companies
The Estée Lauder CompaniesNYSE: EL: Manufactures and markets prestige skincare, makeup, and fragrance products.
9+ YOEAdvanced scientific degree, extensive experience in skin biology, leadership of scientific projects, experimental design, and claim substantiation for consumer brands.
2w
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Principal Scientist - Advanced Technology (25376)
Melville, New York, United States
$115k-$125k/yr OnsiteFull Time
Estée Lauder Companies
Estée Lauder CompaniesNYSE: EL: Manufacturer and marketer of prestige beauty and skincare products.
9+ YOEAdvanced degree in relevant science, minimum ~9 years experience, leadership/mentorship experience, ability to design experiments and develop scientific assets, ~10% travel.
5d
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Senior Principal/ Principal Scientist, Computational Safety
Ridgefield, Connecticut, United States
$140k-$269k/yr OnsiteFull Time
Boehringer Ingelheim
Boehringer Ingelheim: Researches and develops pharmaceutical products for humans and animals.
7+ YOEPh.D. in a relevant computational or molecular field, 7+ years postdoctoral or industry experience, and at least 3 years in safety risk assessment; expertise in computational toxicology, AI/ML, and multi-omics.
AI/ML, multi-omics, Adverse Outcome Pathways, foundation models
2mo
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Principal ML/AI Cheminformatics Scientist
Groton, Connecticut, United States
$106k-$177k/yr HybridFull Time
Pfizer
PfizerNYSE: PFE: Develops and manufactures vaccines and medicines for global healthcare
4+ YOEPhD (4+ years) or Master’s (9+ years) in cheminformatics/computational chemistry/data science; experience applying ML/AI to medicinal chemistry; strong Python and cheminformatics library experience (RDKit, OpenEye, DeepChem); strong collaboration and communication skills.
Python, RDKit, OpenEye, DeepChem, InChI, SMILES, SMARTS
4d
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Principal Data Scientist - Digital MRO (On Site)
East Hartford, Connecticut, United States
$108k-$205k/yr OnsiteFull Time
RTX
RTXNYSE: RTX: Provides advanced aerospace and defense systems and services.
8+ YOEBachelor's degree with 8+ years or associate's degree with 10+ years developing Python, NumPy, Pandas, and scikit-learn for statistical or machine learning applications.
Python, NumPy, Pandas, scikit-learn, Databricks, SQL, NoSQL, Power BI, Qlik, GenAI, LLM
2mo
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Principal Engineer/Scientist - MA Licensed Site Professional
Wakefield or Boston or Braintree or Clifton Park or Manchester or Middletown or Portland or Springfield
$131k-$223k/yr HybridFull Time
Arcadis
ArcadisEuronext Amsterdam: ARCAD: Global design, engineering, and consultancy for natural and built assets.
15+ YOEBachelor's in engineering/geology/hydrogeology, active Massachusetts Licensed Site Professional (LSP), 15+ years environmental consulting experience in Massachusetts; PE/PG/CT LSP preferred; ability to lead teams, prepare investigation and remedial plans, and serve as LSP-of-record.
3mo
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Principal Scientist, Precision Medicine Strategy Lead (Clinical Biomarkers)
Tarrytown, New York, United States
$129k-$210k/yr OnsiteFull Time
Regeneron
RegeneronNasdaq: REGN: Discovers and manufactures medicines for serious diseases.
5+ YOEPhD with 5+ years in pharma/biotech translational clinical development; strong communication; matrixed collaboration; biomarker strategy experience; advantage for industry documents.
Biomarker assay development, Clinical development, Translational medicine, Data interpretation
1mo
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Data Science Sr. Principal Engineer – Commercial DPHM P5 (Onsite)
East Hartford, Connecticut, United States
$132k-$252k/yr OnsiteFull Time
RTX
RTXNYSE: RTX: RTX provides advanced aerospace and defense systems and services.
10+ YOESTEM bachelor's degree with 10 years engineering experience (or advanced degree with 7 years). U.S. Person required. Expertise in statistics, ML/AI, time series, Python, MLOps, and technical leadership.
Python