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17 principal scientist jobs at 10 companies in Minnesota

4w
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Principal D&T Data Scientist
Minneapolis, Minnesota, United States
$150k-$249k/yr RemoteFull Time
General Mills
General MillsNYSE: GIS: Public multinational food manufacturer and marketer serving consumers and pets with cereals, snacks, meals and pet food.
10+ YOE10+ years in data science or applied analytics, including 3+ years at principal or equivalent senior technical level; advanced quantitative degree; expertise in AI/ML, optimization, cloud architecture, and technical leadership.
Agentic AI, NLP, machine learning, GCP, LLMs, computer vision, retrieval-augmented systems, RAG, version control, CI/CD, agile
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1mo
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Principal Clinical Scientist
Chaska or Miami
$120k-$165k/yr HybridFull Time
Beckman Coulter
Beckman Coulter: -owned life sciences supplying research instruments and reagents to academic, biopharmaceutical, clinical, and industrial laboratories.
9+ YOEDesign and lead clinical studies for US/EU diagnostics, ensure regulatory compliance, author study documentation, and collaborate with cross-functional teams; advanced degree or extensive clinical research experience required.
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2mo
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Principal Data Scientist
Eden Prairie or United States
$113k-$193k/yr RemoteFull Time
UnitedHealth Group
UnitedHealth GroupNYSE: UNH: Diversified health care helping people live healthier lives.
8+ YOE8+ years in ML/AI/applied data science, strong Python (PyTorch/TensorFlow/Pandas), production ML and SQL experience, experience with distributed data platforms and cloud (AWS/Azure/GCP) preferred.
Python, PyTorch, TensorFlow, Pandas, SQL, Snowflake, Spark, Databricks, AWS, Azure, GCP, EHR, ICD, CPT, SNOMED, FHIR, HL7, LLM, Retrieval-augmented generation (RAG)
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1mo
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Principal Scientist, Microbiology
St. Paul, Minnesota, United States
$138k-$174k/yr OnsiteFull Time
U.S. Pharmacopeia
U.S. Pharmacopeia: Independent nonprofit scientific organization setting quality standards for medicines, dietary supplements, and food ingredients worldwide.
10+ YOEM.S. in relevant field with 10+ years experience; expertise in microbiology product development, environmental monitoring, sterility/bioburden testing, data analysis, assay execution, and cross-functional leadership.
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5d
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Principal Scientist - Process & Formulation
Maple Grove, Minnesota, United States
$142k-$190k/yr HybridFull Time
Bora Pharmaceuticals
Bora PharmaceuticalsTaiwan Stock Exchange (TWSE): 6472: Public Taiwanese CDMO serving pharmaceutical and biotech partners with formulation, manufacturing, and packaging globally.
3+ YOEBachelor's with 10+ years, master's with 5+ years, or PhD with 3+ years in pharmaceutical development or manufacturing; 5+ years with oral solid dosage formulation, process development, scale-up, or technology transfer.
Quality by Design (QbD), Design of Experiments (DOE), cGMP, FDA, EMEA, Standard Operating Procedures (SOP)
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6d
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Principal Data Scientist - Remote
Eden Prairie or United States
$113k-$193k/yr RemoteFull Time
Optum Insight
Optum Insight: Optum Insight is a healthcare analytics and technology-services business serving payers, providers, governments and life sciences companies.
10+ YOE5+ MgmtRequires 10+ years in machine learning or data science, 5+ years building business ML models and leading technical teams or complex AI/ML projects, plus Python, deep learning, transformer, and multimodal modeling experience.
Python, PyTorch, TensorFlow, Transformers, LLMs, AWS, Hadoop, Spark, Mamba, GNNs
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1w
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Principal Data Scientist - Remote
United States or Minnetonka or Minnesota or Washington, D.C.
$113k-$193k/yr RemoteFull Time
UnitedHealthcare
UnitedHealthcare: For-profit U.S. health insurer offering employer, individual, Medicare and Medicaid health benefit plans.
10+ YOE10+ years designing production ML solutions; 3+ years building LLM applications; deep NLP or computer vision expertise; Python, deep learning, cloud ML, Docker/Kubernetes, and MLOps experience required.
LangChain, LangGraph, AWS, Azure, GCP, Docker, Kubernetes, Python, PyTorch, TensorFlow, MLflow, Kubeflow, TFX, Airflow, Apache Spark, Hadoop, Dask, Tableau, Power BI, LLM, GANs
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3w
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Principal Clinical Scientist (Neurodegenerative)
Chaska or European Union
$120k-$130k/yr OnsiteFull Time
Beckman Coulter
Beckman Coulter: -owned life sciences supplying research instruments and reagents to academic, biopharmaceutical, clinical, and industrial laboratories.
9+ YOEBachelor’s degree plus 9+ years, master’s plus 12+ years, or doctoral degree plus 4+ years in clinical research. Requires US/EU trial expertise, diagnostics knowledge, data interpretation, and cross-functional communication.
FDA 510(k), PMA, CE-IVDR
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1mo
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Principal AI Research Scientist
Minneapolis or Atlanta or Chicago or Charlotte or Irving
$150k-$176k/yr HybridFull Time
U.S. Bank
U.S. BankNew York Stock Exchange: USB: Diversified financial services and banking institution.
8+ YOE8+ years AI/ML research and development experience; bachelor’s degree or equivalent; deep expertise in LLMs, generative AI, transformers, and production deployment; strong Python and ML framework skills.
Python, PyTorch, Hugging Face, Langchain, LangGraph
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3w
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Principal Data Scientist - Marketing Analytics
Arden Hills or Maple Grove
$102k-$194k/yr HybridFull Time
Boston Scientific
Boston ScientificNYSE: BSX: Global medical technology leader providing innovative solutions for patients.
8+ YOEMaster’s degree in a related analytical field, 8+ years of data science or related experience, advanced Python and SQL, machine learning and statistical modeling, cloud analytics, and stakeholder communication skills.
Python, SQL, scikit-learn, statsmodels, XGBoost, PyMC-Marketing, Google Meridian, Snowflake, MLOps, LLM
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3w
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Principal Data Scientist - Marketing Analytics
Maple Grove or Arden Hills or Minneapolis or Massachusetts
$102k-$194k/yr HybridFull Time
Boston Scientific
Boston ScientificNYSE: BSX: Global medical technology leader providing innovative solutions for patients.
8+ YOEMaster’s degree in a related quantitative field, 8+ years of data science or analytics experience, advanced Python and SQL, and experience with statistical or machine learning models and cloud analytics environments.
Python, SQL, scikit-learn, statsmodels, XGBoost, PyMC-Marketing, Google Meridian, Snowflake, MLOps, GenAI, LLM
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3w
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Principal Data Scientist - Marketing Analytics
Arden Hills or Maple Grove
$102k-$194k/yr HybridFull Time
Boston Scientific
Boston ScientificNYSE: BSX: Global medical technology leader providing innovative solutions for patients.
8+ YOEMaster’s degree and 8+ years in data science or related analytics; advanced Python and SQL; experience with machine learning, statistical modeling, cloud analytics, and cross-functional communication.
Python, SQL, scikit-learn, statsmodels, XGBoost, PyMC-Marketing, Google Meridian, Snowflake, MLOps, LLM
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1w
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Sr Principal Data Scientist - Remote
Minnetonka or United States
$135k-$231k/yr RemoteFull Time
UnitedHealthcare
UnitedHealthcare: For-profit U.S. health insurer offering employer, individual, Medicare and Medicaid health benefit plans.
10+ YOEBachelor's degree or equivalent experience; 10+ years in data science or related quantitative disciplines; 5+ years with Python, R, SQL, and machine learning frameworks; leadership, experimentation, and model validation experience.
Python, R, SQL, Scikit-learn, TensorFlow, PyTorch, XGBoost, AWS, Azure, GCP, MLOps
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2w
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Data Scientist, Principal - AI Product Engineering
Oakland or Washington or Ohio or District of Columbia or California or Long Beach or Arizona or Colorado or Connecticut or Florida or Georgia or Maryland or Minnesota or Nevada or Oregon or El Dorado Hills or San Diego or Woodland Hills or Alabama or Illinois or Virginia or Wisconsin or Texas or New York
$161k-$242k/yr HybridFull Time
Stellarus
Stellarus: A healthcare organization developing innovative, scalable solutions to improve healthcare quality, affordability, and member experience.
10+ YOEBachelor's degree or equivalent practical experience and 10 years in data science, machine learning, AI/ML, software engineering, or advanced analytics. Requires Python, APIs, ML infrastructure, PyTorch, TensorFlow, LangChain, and LangGraph.
Python, PyTorch, TensorFlow, LangChain, LangGraph, Azure, Google Cloud, AWS, SQL, Spark, CI/CD, MLOps, LLMOps
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4w
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Associate Principal Product Guidance Scientist - Pet
Minneapolis, Minnesota, United States
$111k-$166k/yr OnsiteFull Time
General Mills
General MillsNYSE: GIS: Public multinational food manufacturer and marketer serving consumers and pets with cereals, snacks, meals and pet food.
7+ YOEMaster's or PhD in sensory, behavioral, psychology, animal, consumer science, or related field; 7+ years of relevant pet experience; expertise in sensory science, experimental design, statistics, and product research.
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1mo
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Principal Applied Data Scientist - Search and Browse (NLP, Vector Search, LLMs)
Sunnyvale or Brooklyn Park
$168k-$356k/yr HybridFull Time
Target
TargetNYSE: TGT: An American general merchandise retailer.
8+ YOEPhD or MS in quantitative field,8+ years building and scaling ML systems for search/recommendation/AI,expertise in semantic retrieval,vector search,LLMs,RAG,Python,VertexAI,leadership and product judgement.
Python, VertexAI
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6d
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Senior or Principal Scientist, Formulation and Process Development
Minneapolis, Minnesota, United States
$150k-$175k/yr OnsiteFull Time
Celcuity
CelcuityNasdaq Capital Market: CELC: Publicly traded commercial-stage biotechnology developing and commercializing targeted therapies for breast cancer and other solid tumors.
7+ YOEPhD, MS, or BS in a relevant pharmaceutical or scientific field and 7+ years of pharmaceutical development experience, with expertise in formulation, drug product development, sterile parenteral dosage forms, and physicochemical characterization.
Microsoft Office
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