57 principal scientist jobs at 18 companies in Washington
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Principal Experimental Scientist - RF
Everett, Washington, United States
$230k-$270k/yr OnsiteFull Time
10+ YOEPhD in physics, plasma physics, electrical engineering, or related field; 10+ years in lab/R&D with plasma systems; expertise in RF plasma sources and diagnostics.
RF hardware, Antenna design, Vacuum systems, Plasma diagnostics, RF-plasma interactions
2mo
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Principal Scientist - Cell Therapy Translational Research
Seattle, Washington, United States
$152k-$185k/yr OnsiteFull Time
8+ YOELead translational research in cell therapy; develop biomarker strategies; manage CROs and collaborators; strong communication.
Flow cytometry, Transcriptomics, Proteomics, Biomarker assays, Clinical data analysis
2mo
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Principal Scientist - Cell Therapy Translational Research
Seattle, Washington, United States
$152k-$185k/yr OnsiteFull Time
4+ YOEAdvanced degree in life sciences (BS/MS/PhD) with 4–8+ years industry or academic experience; expertise in immunology/cell therapy, biomarker assays (flow cytometry, transcriptomics, proteomics), data analysis, translational strategy, CRO oversight, and regulatory writing.
3mo
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Principal Applied Scientist, Amazon Payments
Seattle, Washington, United States
$199k-$269k/yr OnsiteFull Time
10+ YOE2+ MgmtPhD or MSc in CS; 10+ years AI/ML; strong research, collaboration, delivery; leadership in teams; excellent communication.
Python, Machine Learning, Natural Language Processing, GenAI, TensorFlow, PyTorch
1w
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Principal Data Scientist
Redmond or Las Colinas or Charlotte or Fargo
$131k-$277k/yr HybridFull Time
10+ YOEBachelor's degree in computer science, information technology, or related field and 10+ years of technical support, consulting, or IT experience; expert causal inference, statistics, machine learning, Python or R, and SQL.
Python, R, SQL, DoWhy, EconML, CausalML, matplotlib, seaborn, plotly, Microsoft AI
2mo
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Principal, Data Scientist
Bellevue, Washington, United States
$132k-$264k/yr OnsiteFull Time
3+ YOEBachelor's degree with 5 years, master's degree with 3 years, or 7 years of analytics experience; advanced machine learning, statistics, Python, SQL/Hive, Spark, and stakeholder management skills required.
Python, Java, Scala, SQL, Hive, Spark, R, scikit-learn, TensorFlow, Torch, Kaggle, Microsoft Excel
1mo
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Principal Data Scientist
Seattle, Washington, United States
$131k-$197k/yr OnsiteFull Time
10+ YOE10+ years building and deploying ML/AI solutions; strong Python and ML framework skills; expertise in forecasting, optimization, experimentation, and model lifecycle; experience with cloud platforms and visualization tools.
Python, Power BI, Plotly, Matplotlib, AWS, Azure, Snowflake, MLOps, CI/CD
2mo
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Principal, Data Scientist
Bellevue, Washington, United States
$132k-$264k/yr OnsiteFull Time
3+ YOEAdvanced ML and statistics expertise; experience architecting large-scale ML systems; strong Python and SQL skills; experience with Spark/Hive; PhD or Master’s with significant experience or extensive industry experience as specified.
Python, Java, Scala, SQL, Hive, Spark, Kaggle, scikit-learn, TensorFlow, PyTorch, R
2mo
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Principal Applied Scientist
Bellevue, Washington, United States
$200k-$250k/yr OnsiteFull Time
10+ YOEMS/PhD preferred in CS/ML/AI, 10+ years industry ML experience building production ML systems, strong Python, expertise with LLMs/foundation models, distributed training, model deployment, and excellent communication.
Python
1mo
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Principal Scientist, Immunology
San Francisco or Seattle
$175k-$190k/yr RemoteFull Time
8+ YOEPhD in immunology or related field with 8+ years industry experience; deep immunology expertise, drug development knowledge, experience with immunological assays (flow cytometry, ELISA/MSD), strong communication and publication record.
flow cytometry, ELISA/MSD, cytokine panels, cellular assays, single-cell, proteomics
1w
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Principal Applied Scientist (200045521)
Redmond, Washington, United States
OnsiteFull Time
No qualifications or experience requirements are specified in the posting.
2mo
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Senior/Principal Fisheries Scientist
Wenatchee or Seattle or Portland or Washington or Oregon or Idaho or California or Montana
$110k-$145k/yr RemoteFull Time
10+ YOEBachelor's in fisheries science/biology/ecology required (Masters/Doctorate preferred); 10+ years experience in Pacific Northwest salmonid issues; expertise in fish passage, ESA consultation, hatchery operations, study design, quantitative analysis, project management, and staff supervision; valid driver’s license.
2mo
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Senior Principal Data Scientist, AEC
California or Washington or New York or British Columbia or Ontario or Irvine
$159k-$286k/yr RemoteFull Time
10+ YOE10+ years in data science/applied ML focused on product analytics and user behavior modeling; expertise in predictive modeling, instrumentation, AI evaluation, and experimentation; strong communication and technical leadership.
LLMs, MCP, RAG architectures, LLM-as-a-Judge, A/B testing
2mo
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Principal AI/ML Applied Scientist
Seattle, Washington, United States
$267k-$350k/yr HybridFull Time
11+ YOEBachelor's in CS/data/engineering or equivalent; 11+ years AI/ML research experience; deep expertise in generative AI, NLP, computer vision, multimodal learning; experience with Python and PyTorch; ability to lead enterprise AI strategy and translate research to production.
Python, PyTorch
6d
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Principal Data Scientist, Google Search
Mountain View or Kirkland or New York City or Seattle or San Francisco
$307k-$427k/yr OnsiteFull Time
15+ YOEBachelor’s degree or equivalent practical experience; 15 years in data science or quantitative fields; experience using data insights to improve products and engineering; advanced degree and product-building experience preferred.
AI
2mo
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Principal Research Scientist, Siri Innovation Studio
Seattle, Washington, United States
OnsiteFull Time
Expertise in machine learning modeling, incubating and deploying ML-driven features, collaborating across software/hardware/design teams, and building user-centered AI for assistants and speech products.
iOS, iPadOS, macOS, watchOS, visionOS
1mo
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Senior / Principal Clinical Scientist, Clinical Development
Bothell, Washington, United States
$146k-$226k/yr OnsiteFull Time
2+ YOEAdvanced degree (PhD/MD/PharmD/MS) in life sciences, minimum 2 years clinical development experience, oncology/biopharma experience preferred, strong leadership, project management, regulatory and data analysis skills.
4d
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Data Scientist, Principal - AI Product Engineering
Oakland or Washington or Ohio or District of Columbia or California or Long Beach or Arizona or Colorado or Connecticut or Florida or Georgia or Maryland or Minnesota or Nevada or Oregon or El Dorado Hills or San Diego or Woodland Hills or Alabama or Illinois or Virginia or Wisconsin or Texas or New York
$161k-$242k/yr HybridFull Time
10+ YOEBachelor's degree or equivalent practical experience and 10 years in data science, machine learning, AI/ML, software engineering, or advanced analytics. Requires Python, APIs, ML infrastructure, PyTorch, TensorFlow, LangChain, and LangGraph.
Python, PyTorch, TensorFlow, LangChain, LangGraph, Azure, Google Cloud, AWS, SQL, Spark, CI/CD, MLOps, LLMOps
2w
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Principal Machine Learning Scientist - Agentic Experiences
Seattle or San Jose
$224k-$339k/yr OnsiteFull Time
10+ YOEBS or equivalent,10+ years industry experience, proven experience building agentic/multi-step AI systems, strong Python and ML framework skills, experience with LLM APIs and orchestration, evaluation and productionization experience.
Python, PyTorch, TensorFlow, JAX, LLM APIs, LangChain, LlamaIndex
1mo
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Principal Scientist - Data Pipeline Engineer
San Jose or Seattle or San Francisco
$206k-$388k/yr OnsiteFull Time
10+ YOE10+ years in data engineering/ML infrastructure, distributed systems expertise, Python and a systems language, experience with Ray or Spark, GPU inference optimization, large-scale databases and data curation for model training.
Ray, Spark, Python, C++, Rust, Go, Java
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