45 principal scientist jobs at 13 companies in Winfield, IL

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Principal Scientist
Wood Dale, Illinois, United States
OnsiteFull Time
Chem-Impex International
Chem-Impex International: Family-run laboratory chemical manufacturer and distributor serving researchers with research chemicals, custom synthesis, and quality testing.
Advanced degree (PhD or MS) in Chemistry/Biochemistry, hands-on peptide synthesis and SPPS experience, ability to translate technical insight into commercial products, presentation and customer engagement experience, willingness to travel.
3d
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Principal Scientist I, Chemistry
North Chicago, Illinois, United States
$125k-$237k/yr OnsiteFull Time
AbbVie
AbbVieNYSE: ABBV: Global biopharmaceutical discovering and delivering innovative medicines.
6+ YOEBachelor’s with typically 14+ years, master’s with 12+ years, or PhD with 6+ years in organic chemistry, focused on manufacturing process development and scale-up; expertise with modern organic chemistry and analytical methods.
HPLC, UPLC, LC-MS, NMR, GxP
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Principal Applied Scientist
Walnut Creek or New York City or Chicago
$214k-$350k/yr HybridFull Time
Elevance Health
Elevance HealthNYSE: ELV: A health dedicated to improving lives and communities.
10+ YOEMS or PhD in a quantitative field and 10+ years in ML/AI; experience leading AI initiatives to production; proficiency with Python, machine learning frameworks, cloud AI platforms, MLOps, model deployment and monitoring.
Python, MLOps
2d
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Principal Scientist - Cocoa chemistry and flavor
Chicago, Illinois, United States
$154k-$211k/yr OnsiteFull Time
Mars, Incorporated
Mars, Incorporated: Global food, snacking, and pet care products.
8+ YOEPhD in food science, food or chemical engineering, biochemical, or related field; 8+ years in food or applicable industry; expertise in cocoa chemistry, flavor, fermentation, analytical chemistry, research, and global project management.
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Principal Scientist – Data Insights & Hypothesis Design
Chicago or Redwood City or New York City or California or New York
$150k-$200k/yr HybridFull Time
Tempus AI
Tempus AINASDAQ: TEM: AI-enabled precision medicine and health technology.
6+ YOEPhD in NGS-related field,6+ years industry experience,domain expertise in oncology/neurology/immunology,large-scale clinico-genomic analysis,SQL/Python/R proficiency,and experience translating data into production products.
SQL, R, Python, Tempus Data Model (TDM)
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Associate Principal Scientist, Analytical & Material Science
Hoffman Estates, Illinois, United States
$71k-$104k/yr OnsiteFull Time
Tate & Lyle
Tate & LyleLondon Stock Exchange: TATE.L: Public speciality food and beverage ingredient manufacturer supplying sweetening, mouthfeel, fortification and fibre solutions to food makers.
3+ YOEPhD in material, food, polymer, analytical chemistry, or related science; 3+ years applied research experience, or 6+ years with a master's; expertise in food physics, rheology, material characterization, and statistical modeling.
rheometers, tribometers, particle size analyzers, SEM, optical microscopes, Design of Experiments (DoE), Minitab, Python, R, JMP, mass spectrometry, chromatography
3w
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Principal Scientist, R&D – Consumer Experience (CX) Product Insights​
Glenview, Illinois, United States
$104k-$130k/yr HybridFull Time
The Kraft Heinz Company
The Kraft Heinz CompanyNASDAQ: KHC: Multinational food and beverage with iconic global brands.
6+ YOEBachelor's degree, 6+ years consumer/product research experience (CPG preferred); expertise in qualitative and quantitative CX methods, study design, analysis, synthesis, stakeholder communication, and coaching.
3w
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Principal Scientist, R&D – Consumer Experience Packaging Research SME
Glenview, Illinois, United States
$104k-$130k/yr HybridFull Time
The Kraft Heinz Company
The Kraft Heinz CompanyNASDAQ: KHC: Multinational food and beverage with iconic global brands.
6+ YOEBachelor's degree in relevant field required (advanced degree preferred); 6+ years' experience in consumer/product research or CX; expertise in qualitative/quantitative methods; packaging research experience; strong communication and coaching skills.
2w
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Principal Data Scientist
Amelia or Cary or Evansville or Chillicothe or Chesapeake or Durham or Berea or Columbus or Clarksville or Boca Raton or Indianapolis or Buffalo or Charleston or Dayton or Athens or Knoxville or Clearwater or Chicago or Arlington or Cleveland or Gaylord or Carmel or Ann Arbor or Bloomington or Cincinnati or Bremen or Charlotte or Circleville or Birmingham or Chattanooga
HybridFull Time
American Modern Insurance Group
American Modern Insurance Group: American Modern is a private specialty insurer serving residential-property and recreational-vehicle owners across the United States.
6+ YOEFCAS and a master's degree required; 6+ years of insurance data science or 8+ years of predictive modeling experience. Requires R, Python, GLMs, GBMs, machine learning, and project management.
R, Python, Databricks, Scrum, Kanban, Microsoft Excel
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Principal Data Scientist - FDE
United States or Redmond or Mountain View or Austin or Houston or Chicago or Cambridge or New York City or Atlanta
$143k-$275k/yr RemoteFull Time
Microsoft
MicrosoftNASDAQ: MSFT: Multinational technology providing software, cloud, and AI solutions.
3+ YOERequires a doctorate and 3+ years, master's and 5+ years, or bachelor's and 7+ years in data science or a related field; customer-facing delivery experience preferred and travel up to 25%.
AI
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Principal AI Research Scientist
Minneapolis or Atlanta or Chicago or Charlotte or Irving
$150k-$176k/yr HybridFull Time
U.S. Bank
U.S. BankNew York Stock Exchange: USB: Diversified financial services and banking institution.
8+ YOE8+ years AI/ML research and development experience; bachelor’s degree or equivalent; deep expertise in LLMs, generative AI, transformers, and production deployment; strong Python and ML framework skills.
Python, PyTorch, Hugging Face, Langchain, LangGraph
2mo
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Senior/Principal Engineer or Scientist, Combination Products
Bern or Munich or Switzerland or Research Triangle Park or Boston or Chicago or Philadelphia or New Jersey
HybridFull Time
Kymanox
Kymanox: Life sciences professional services and consulting firm helping pharmaceutical, biotechnology, and medical-device companies develop and commercialize medicines.
8+ YOEMinimum 8+ years in medical device, pharmaceutical, or combination product industries, bachelor's in engineering or science required, subject matter expertise in combination products, technical leadership and client-facing experience.
2mo
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Principal Associate, Data Scientist - Global Payments Network: Data Solutions and Modeling
Chicago, Illinois, United States
$147k-$168k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: A technology-driven bank providing diverse financial services.
5+ YOEQuantitative bachelor's degree plus 5 years, master's or quantitative MBA plus 3 years, or PhD. Preferred: 3+ years in Python, Scala, or R, machine learning, and SQL; LLM and AI agent experience.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL, Large Language Models (LLMs)
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Principal Associate, Data Science - Model Risk Office
McLean or Chicago or New York City or Plano
$162k-$185k/yr OnsiteFull Time
Capital One
Capital OneNYSE: COF: A technology-driven bank providing diverse financial services.
3+ YOEDegree in a quantitative field (BS+5yrs, MS+3yrs, or PhD) with 3+ years data analytics experience typical; strong skills in Python, Spark, SQL, AWS, model validation, machine learning, and leadership.
Python, Conda, AWS, H2O, Spark, Scala, R, SQL
1w
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ACS Conference (Chicago 2026)
Sugar Land or Odessa or Chicago
OnsiteFull Time
Chemical Technologies
Chemical TechnologiesNYSE: CHX: Oilfield technology supplying chemistry, artificial lift, drilling, automation, and emissions solutions for oil-and-gas operators.
2+ YOEChemistry or related technical degree required. Qualifications range from a B.S. for Chemist roles to advanced degrees and relevant experience for senior, principal, lead, group leadership, scientist, engineer, and reservoir engineering roles.
nanotechnology