104 protein jobs at 53 companies in Massachusetts
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Senior /Principal Scientist, Protein Science
Cambridge, Massachusetts, United States
OnsiteFull Time
3+ YOEAdvanced degree in protein/biophysical discipline, industry experience in therapeutic protein characterization, hands-on expertise with analytical and biophysical techniques, and ability to lead characterization strategies and mentor scientists.
Python
2d
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Scientist/Sr. Scientist, Protein Purification
Cambridge, Massachusetts, United States
$125k-$170k/yr OnsiteFull Time
2+ YOEPhD preferred in analytical chemistry, protein engineering, biochemistry, or related field; BS/MS with substantial experience considered. Requires 2+ years post-degree protein purification experience, or 4+ years for senior level.
SEC, IEX, RP-HPLC, AKTA, AKTA pure, AKTA avant, mass spectrometry, DLS, MALS, SPR, BLI, DSF, flow cytometry, cryo-EM, X-ray crystallography
1mo
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Principal Scientist, Protein Production & Engineering
Watertown or Massachusetts
$166k-$203k/yr HybridFull Time
10+ YOEPhD in relevant field,10+ years related experience with ≥5 years in biotech/pharma; extensive biologics and protein science expertise; ability to lead discovery, design and characterize proteins; strong communication and analytical skills.
1mo
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Protein Cook / Saucier
Boston or Boston or Boston
$48k-$91k/yr OnsiteFull Time
GED required; culinary training preferred; proven hot-line fine-dining or hotel experience; classic sauce proficiency; knowledge of allergens and dietary restrictions; ServSafe preferred or willing to obtain within 30 days; strong knife and meat/poultry/fish skills.
2w
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Sr. Scientist, Generative Protein Design
Cambridge, Massachusetts, United States
$131k-$207k/yr OnsiteFull Time
0+ YOEPhD/MS/BS with industry experience pathway; expertise in generative AI/ML protein design, structural biology, and integrating experimental data; strong communication and collaborative skills.
RFdiffusion, Boltzgen, BindCraft, ProteinMPNN, AlphaFold, Generative AI, Machine Learning (ML)
1w
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Principal Scientist, Computational Protein Design
Cambridge, Massachusetts, United States
$143k-$257k/yr HybridFull Time
5+ YOEPhD and 5+ years post-graduate experience in computational protein design with de novo binder generation, ML-guided design, experimental integration, leadership, and strong publication record.
AlphaFold, AlphaFold-Multimer, Rosetta, PyRosetta, RFdiffusion, ProteinMPNN, Python
1w
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Senior Director, Protein Analytics & Biophysics
Somerville, Massachusetts, United States
$210k-$290k/yr OnsiteFull Time
12+ YOEPhD-level scientific leader with 12+ years in biopharma/biotech and substantial leadership in protein analytics, experience with high-throughput and miniaturized assay platforms, strong quantitative and cross-functional partnership skills.
HPLC/UPLC, LC/MS, CE-SDS, cIEF, DSF, DSC, DLS, SEC-MALS, SPR, BLI, microfluidics, AI/ML, sequencing
5d
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Sr. Scientist, Generative Protein Design
Cambridge, Massachusetts, United States
$131k-$207k/yr OnsiteFull Time
0+ YOEPh.D. with 0–3 years industry experience, MS with 4+ years, or BS with 7+ years. Requires protein design, structural biology, generative AI/ML, experimental data analysis, and cross-functional collaboration expertise.
Machine Learning (ML), Generative AI, RFdiffusion, Boltzgen, BindCraft, ProteinMPNN, AlphaFold
1mo
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Protein Cook / Saucier
Boston, Massachusetts, United States
$48k-$91k/yr OnsiteFull Time
GED required; hot line experience, sauce work, allergen knowledge, meat, poultry and fish cookery, butchering, carving, classic cuts, and knife skills. ServSafe preferred.
ServSafe
1mo
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Scientist II/Senior Scientist, Protein Sciences – Cell Binding Assays
Boston, Massachusetts, United States
$125k-$175k/yr OnsiteFull Time
3+ YOEPhD with 3+ years (or MS with 8+ years) biotech/pharma experience, expertise in mammalian cell line engineering, FACS and cell-based assay development, antibody characterization, and independent experimental design.
FACS, Flow cytometry, Cell ELISA, SPR, BLI, Biacore, Octet
2d
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Scientist/Sr. Scientist, Protein Purification
Cambridge, Massachusetts, United States
$125k-$170k/yr OnsiteFull Time
2+ YOEPhD preferred, or BS/MS with significant industry experience; 2+ years of protein purification experience for Scientist or 4+ years for Senior Scientist; expertise in protein and peptide purification and analytical characterization.
SEC, IEX, RP-HPLC, CE, mass spectrometry, cryo-EM, X-ray crystallography, flow cytometry, AKTA pure, AKTA avant, DLS, MALS, SPR, BLI, DSF, AI/ML
1d
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Scientist, Protein Science - Purification
South San Francisco or Cambridge
$125k-$145k/yr OnsiteFull Time
3+ YOERequires MS or PhD in a relevant life science, protein purification expertise, AKTA and Unicorn proficiency, experimental design skills, and strong communication and teamwork abilities.
AKTA, Unicorn, SDS-PAGE, HPLC
16h
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Senior Scientist, Protein Engineering
Cambridge, Massachusetts, United States
$126k-$182k/yr OnsiteFull Time
5+ YOEPhD and 5+ years of industry or postdoctoral experience required, with expertise in molecular biology, membrane protein engineering, plasmid engineering, molecular cloning, lentiviral transduction, and mammalian cell culture.
Rosetta, AlphaFold-Multimer, RFdiffusion, ProteinMPNN, FlowJo, Benchling
3w
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Associate Scientist, Protein Science
Waltham, Massachusetts, United States
$93k-$110k/yr OnsiteFull Time
2+ YOEMS+2yrs or BS+4yrs in molecular/cell biology or related field; hands-on experience with mammalian transient expression, recombinant DNA, cell culture scale-up, protein purification, QC assays, and ELN/LIMS.
AKTA, aSEC, CE-SDS, SDS-PAGE, Vi-CELL, LIMS, Electronic laboratory notebook (ELN)
2w
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Product Manager, Antibody & Protein Portfolio
Boston, Massachusetts, United States
$130k-$160k/yr HybridFull Time
5+ YOEPh.D. or M.S. in relevant field and minimum 5 years industry experience; deep knowledge of antibody/protein product lifecycle, market analysis, portfolio management, and cross-functional collaboration.
1mo
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Research Scientist I - Protein Sciences and Structural Biology
Cambridge, Massachusetts, United States
$88k-$124k/yr OnsiteFull Time
0+ YOEPh.D. in a relevant life science, experience with recombinant protein design, expression, purification, and characterization; protein crystallography and biophysical methods a plus.
FPLC, SDS-PAGE, Western blot, LC/MS, AKTA pure, ITC, DSC, SPR, NMR
1mo
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Research Associate, Protein Chemistry & Bioconjugation (6 MONTH CONTRACT)
Cambridge, Massachusetts, United States
OnsiteContract
1+ YOEB.S. or M.S. in a relevant field, 1+ years lab experience, proficiency in protein workflows and bioconjugation chemistries, experience with protein analytics and purification, strong documentation and independent bench skills.
Electronic Lab Notebook (ELN), µPulse TFF, TFF, SEC-HPLC, Analytical HPLC, IMAC, SEC, Ion exchange chromatography, GraphPad Prism, ImageJ, UV-Vis spectroscopy, BCA, Bradford, SDS-PAGE, DLS
2mo
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Scientist-Principal Scientist, Protein Design & Structure
Boston, Massachusetts, United States
OnsiteFull Time
2+ YOEPhD in Biochemistry/Molecular Biology/Biophysics with 2+ years (Scientist) or 5+ years (Senior Scientist) or 8+ years (Principal Scientist) of relevant experience in GPCR/membrane protein expression, purification, and characterization; strong leadership and collaboration skills.
Cryo-EM, FPLC, SEC, Rosetta, AI/ML
2mo
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Principal Scientist – Protein Formulation & Biophysical Characterization (High-Concentration Biologics)
Andover, Massachusetts, United States
$106k-$177k/yr OnsiteFull Time
3+ YOEPhD with 3–5 years in biologics formulation/biophysics; strong hands-on biophysical characterization; experience with subcutaneous delivery considerations and cross-functional collaboration.
Biophysical characterization, DLS, DSC, DSF, SEC-MALS, NTA, CD, FTIR, Fluorescence spectroscopy, Rheology
3mo
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Global Market Development Manager (Protein Expression and Viral Delivery)
Frederick or Austin or Grand Island or Waltham or Carlsbad or Pittsburgh
$94k-$150k/yr OnsiteFull Time
5+ YOEMarketing strategy experience for protein expression or viral delivery; 5+ years life sciences marketing; bachelor’s degree; advanced degree preferred.
Digital marketing tools, Web analytics, SEO, SEM, Email automation
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