48 purification jobs at 34 companies in San Jose, CA

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Principal Scientist, Purification Process Development
South San Francisco, California, United States
$159k-$207k/yr OnsiteFull Time
Denali Therapeutics
Denali TherapeuticsNASDAQ: DNLI: Developing medicines for neurodegenerative and lysosomal storage diseases.
10+ YOEPhD in biology/biochemistry/chemical engineering or related, 10+ years of experience; purification process characterization and validation; PPQ; CMOs; analytical methods (ELISA, HPLC, UV, SDS-PAGE) and biophysical techniques.
AKTA, HPLC, LC/MS, SDS-PAGE, DLS
1d
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Scientist, Protein Science - Purification
South San Francisco or Cambridge
$125k-$145k/yr OnsiteFull Time
Eira Bio
Eira Bio: Developing antibody-based therapies using synthetic biology and directed evolution.
3+ YOERequires MS or PhD in a relevant life science, protein purification expertise, AKTA and Unicorn proficiency, experimental design skills, and strong communication and teamwork abilities.
AKTA, Unicorn, SDS-PAGE, HPLC
3w
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Scientist/Sr Scientist – Protein Production and Purification
Palo Alto, California, United States
OnsiteFull Time
Kodiak Sciences
Kodiak SciencesNASDAQ: KOD: Developing biopolymer conjugate therapeutics for retinal vascular diseases.
3+ YOEExpertise in recombinant protein expression and purification (mammalian and bacterial), chromatographic purification, biochemical/biophysical characterization, and independent experimental design and troubleshooting.
HEK293, CHO, ÄKTA FPLC, KingFisher, SDS-PAGE, SEC, DLS, UV-Vis spectroscopy, mass photometry, Isoelectric focusing (IEF)
1d
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Senior Associate Scientist, Purification Process Development
Foster City, California, United States
$127k-$164k/yr OnsiteFull Time
Gilead Sciences
Gilead SciencesNASDAQ: GILD: Develops and sells medicines for life-threatening infectious diseases.
3+ YOEM.S. with 3+ years or B.S. with 5+ years of industrial biologics purification experience; hands-on chromatography, TFF, VF, and depth filtration experience required.
JMP, Spotfire
2w
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Director of Marketing, Purification and Pharma Analytics
Bedford or Pleasanton or Carlsbad
$160k-$235k/yr OnsiteFull Time
Thermo Fisher Scientific
Thermo Fisher ScientificNYSE: TMO: Sells equipment and chemicals for scientific research and healthcare.
8+ YOEBachelor's required, advanced degree preferred;8+ years marketing experience in life-science tools/diagnostics;experience leading global teams, go-to-market strategy, demand generation, and commercial activation.
1mo
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Postdoctoral Appointee - Complex Metal Alloys for Hydrogen Storage and Purification, Onsite
Livermore, California, United States
OnsiteFull Time, Temporary
Sandia National Laboratories
Sandia National Laboratories: Federal research and development laboratory for national security.
PhD in chemistry, metallurgy, materials science or related field; expertise in alloy synthesis and structural/chemical characterization; experience with glove-box, arc-melting or AM synthesis and advanced diffraction/spectroscopy techniques.
additive manufacturing (AM), automated arc-melting, glove-box techniques, X-ray crystallography, neutron diffraction, Pair Distribution Function (PDF) analysis, electron microscopy, XPS, TEM, solid-state NMR, machine learning, artificial intelligence
1mo
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Postdoctoral Appointee - Complex Metal Alloys for Hydrogen Storage and Purification, Onsite
Livermore or New Mexico or United States or China or IR or KP or RU
OnsiteFull Time, Temporary
Sandia National Laboratories
Sandia National Laboratories: Conducts science and engineering research for national security.
PhD in chemistry/materials/metallurgy or related; expertise in alloy synthesis and structural/chemical characterization; experience with glove-box techniques and diffraction/spectroscopy/electron microscopy; independent research ability.
3w
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Senior Research Associate 1 (Contract)
Millbrae, California, United States
$48-$58/hr OnsiteContract
Eikon Therapeutics
Eikon TherapeuticsNASDAQ: EIKN: Discovers drugs using advanced live-cell imaging and protein tracking.
2+ YOEHands-on experience with small-molecule purification, chromatography (HPLC/SFC), mass-directed purification, 2+ years (Master's) or 4+ years (Bachelor's) relevant experience, instrument troubleshooting, data management, and strong communication.
Waters Autopurifier, Agilent mass-directed purification systems, HPLC-MS, SFC
2w
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Postdoctoral Fellow, Protein Sciences, Kschonsak Lab
South San Francisco, California, United States
$100k-$107k/yr OnsiteFull Time
Roche
RocheSIX Swiss Exchange: ROG: Provides innovative pharmaceutical and diagnostic healthcare solutions.
PhD required; expertise in protein purification and structural biology (cryo-EM and/or X-ray); independent experimental design, strong communication and collaboration skills.
cryo-EM, X-ray crystallography
1mo
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Senior Scientist, Peptide Chemistry (Night Shift)
San Francisco, California, United States
$200k-$260k/yr OnsiteFull Time
Capable
Capable: Early-stage biotech developing novel peptide-based therapeutics.
5+ YOEOvernight lab scientist with 5+ years industry experience in medicinal/organic/peptide chemistry; proficiency in synthesis, purification, analytical characterization, troubleshooting, and rigorous documentation.
Analytical HPLC, Prep HPLC, LC-MS, NMR, Microwave-assisted solid-phase peptide synthesis
2mo
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Sr. Research Associate/Associate Scientist, Protein Biochemistry
Redwood City, California, United States
OnsiteFull Time
Allakos
Allakos: N/A
3+ YOEBS/MS in Biological Sciences with 3-4 years industry experience; protein biochemistry; AKTA purification; SDS-PAGE; UV spectroscopy; HPLC; team-oriented.
AKTA purification, SDS-PAGE, UV spectroscopy, HPLC, Tissue culture
3d
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Research Associate I- Ramani Lab
San Francisco, California, United States
$28-$33/hr OnsiteFull Time
Gladstone Institutes
Gladstone Institutes: Conducts independent biomedical research to discover cures for diseases.
B.S./B.A. in a relevant scientific field by hire, protein purification and biochemistry experience, and skills in molecular biology. Sequencing, tissue culture, bioinformatics, or scripting experience preferred.
Illumina, PacBio, Pacific Biosciences, Oxford Nanopore, UNIX, C++, Python, R
1w
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Junior or Assistant Specialist in Structural Biology*
San Francisco, California, United States
$57k-$73k/yr OnsiteFull Time
University of California
University of California: A public research university system providing education and healthcare.
2+ YOERequires BA/BS in biochemistry or related biological science, or equivalent research experience; laboratory experience in protein purification, biochemistry, cell biology, or microscopy; communication and computer skills.
Transmission Electron Microscopy (TEM), fluorescence microscopy, confocal microscopy, cryo-confocal fluorescence microscopy, cell sorting, Microsoft Office, Macintosh, PC, statistical analysis software, Titan Krios G4, Glacios, L120C TEM, Helios Hydra plasma FIB-SEM
1mo
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Research Associate, Protein Engineering
South San Francisco, California, United States
$80k-$115k/yr OnsiteFull Time
Atlas Data Storage
Atlas Data Storage: A developing semiconductor-based molecular data storage technology using synthetic DNA to drive innovation in information storage.
Bachelor's in chemistry/biochemistry/molecular biology, hands-on experience with protein expression and purification, assay development, molecular biology techniques, data analysis, and strong communication and collaboration skills.
FPLC, SDS-PAGE, UV/Vis, BCA, Next Generation DNA sequencing (NGS), liquid handling laboratory automation
2w
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Scientist, Drug Product Development
South San Francisco, California, United States
$113k-$171k/yr OnsiteFull Time
NewLimit
NewLimit: Developing epigenetic reprogramming medicines to extend human healthspan.
PhD or equivalent experience in biomedical engineering/chemical biology/pharmaceutical sciences, hands-on LNP formulation, purification, and analytical characterization experience, ELN recordkeeping, and statistical data interpretation.
Tangential Flow Filtration (TFF), dialysis, ultracentrifugation, sterile filtration, dynamic or multi-angle light scatting, liquid chromatography, ELISA, qPCR, spectroscopy, Electronic Laboratory Notebook (ELN), R, Python
1d
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Staff Scientist II - Medicinal Chemistry
Newark, California, United States
$135k-$145k/yr OnsiteFull Time
Protagonist Therapeutics
Protagonist TherapeuticsNASDAQ: PTGX: Developing oral peptide therapeutics for complex diseases.
2+ YOEPhD in synthetic organic or medicinal chemistry plus 2–5 years of industrial medicinal chemistry experience; requires synthesis, purification, scale-up, problem-solving, and software proficiency.
Microsoft Office, ChemDraw, SciFinder, Spotfire, electronic lab notebooks
2mo
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SRA Protein Expression
Brisbane or San Francisco
$99k-$153k/yr OnsiteFull Time
Nurix Therapeutics
Nurix TherapeuticsNASDAQ: NRIX: Develops targeted protein degradation medicines for cancer and inflammation.
2+ YOEMS or equivalent with 2+ years experience in insect/baculovirus expression; mammalian expression a plus; strong cell culture, protein purification, and characterization skills; able to lift 50+ pounds.
Baculovirus Expression System, Mammalian Cell Culture, SDS-PAGE, Size Exclusion Chromatography, nanoDSF, Protein Purification
4d
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Synthetic Biologist - Research Scientist
Livermore, California, United States
$146k-$186k/yr OnsiteFull Time, Temporary
Lawrence Livermore National Laboratory
Lawrence Livermore National Laboratory: Develops science and technology for United States national security.
Bachelor’s degree or equivalent experience in a biological science field, molecular biology techniques, bacterial culture, recombinant protein expression and purification, analytical problem-solving, and collaborative research skills.
PCR, Gibson Assembly, Golden Gate Assembly, Bash, ZSH, R, Python
4w
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Scientific Operations Associate
San Francisco, California, United States
$95k-$120k/yr OnsiteFull Time
Merge Labs
Merge Labs: Developing high-bandwidth non-invasive brain-computer interfaces using biotechnology.
Hands-on wet-lab experience (sterile technique, cell culture, reagent prep, protein purification), ability to write/follow SOPs, QC skills, organization, and collaboration across science and operations.
1mo
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Associate Director / Director, Protein Sciences
South San Francisco, California, United States
$195k-$245k/yr HybridFull Time
Cartography Biosciences
Cartography Biosciences: Developing precision oncology immunotherapies using single-cell data and AI.
6+ YOEPhD (or MS with commensurate experience) with 6+ years (Associate Director) or 9+ years (Director) industry experience; CDMO management, mammalian expression, antibody purification, analytical methods, and developability expertise.
AKTA, KingFisher, ELN, LIMS, FPLC, Expi293, ExpiCHO, Python