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848 python backend engineer jobs at 405 companies in South San Francisco, CA

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Sr Backend Engineer
San Francisco or New York
$167k-$219k/yr HybridFull Time
Quizlet
Quizlet: Digital learning platform providing study tools and flashcards.
4+ YOE4+ years backend or data engineering experience; strong SQL and data warehouse experience; proficiency in Python/Java/Scala; Elasticsearch/OpenSearch experience; experience building production data pipelines and backend services.
Elasticsearch, OpenSearch, SQL, Snowflake, BigQuery, Redshift, Python, Java, Scala, Airflow, Dagster, Prefect, dbt, REST, gRPC, Datadog, Prometheus, Grafana, Docker, Kubernetes, AWS, GCP, Azure, Spark, Kafka, Flink, FAISS, ScaNN, pgvector, LightGBM, XGBoost, BM25, HNSW, kNN
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2mo
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Backend Engineer
San Francisco, California, United States
$190k-$230k/yr OnsiteFull Time
Lapel
Lapel: Unifying customer data to power personalized service at scale.
3+ YOE3+ years backend or software engineering; API design; backend architecture; Node.js/Python/Go; PostgreSQL/MySQL; scalable systems; customer-focused.
Node.js, Python, Go, PostgreSQL, MySQL, TypeScript, Temporal, Pulsar
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23h
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Remote Backend Engineer (Python/FastAPI)
San Francisco or United States or Berlin
€200-€300/hr RemoteContract
Turing
Turing: AI-powered platform connecting companies with global remote software developers.
3+ YOE3+ years software engineering experience, strong Python and JavaScript (React, Node.js) skills, production deployment experience, software architecture and debugging, excellent communication.
Python, FastAPI, JavaScript, React, Node.js, C/C++, Java, Rust, Go
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1mo
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Senior Backend Engineer
San Francisco, California, United States
$200k-$230k/yr OnsiteFull Time
Sauron Systems
Sauron Systems: Autonomous robotic platforms for residential security and threat deterrence.
5+ YOE5+ years building production backend systems; proficiency in Go, Python, Rust, Java, or C++; experience with distributed systems, REST/gRPC, PostgreSQL/MySQL/Redis/DynamoDB, AWS, Docker, Kubernetes, and observability; strong system design and debugging skills.
Go, Python, Rust, Java, C++, REST, gRPC, PostgreSQL, MySQL, Redis, DynamoDB, AWS, Docker, Kubernetes, Kafka, NATS, RabbitMQ
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2mo
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Senior Backend Engineer (Python)
San Francisco, California, United States
$175k-$250k/yr RemoteFull Time
Ellipsis Health
Ellipsis Health: AI-powered voice agent for healthcare care management.
4+ YOE4+ years building production back-ends in Python; real-time streaming; AWS/GCP/Azure; PostgreSQL/Redis; FastAPI/asyncio; HIPAA security.
Python, FastAPI, asyncio, WebRTC, WebSockets, gRPC, AWS, GCP, Azure, Kubernetes, Kafka, SQS, Pub/Sub, Terraform, PostgreSQL, Redis, OpenTelemetry
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3mo
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Backend engineer
San Jose, California, United States
$150k-$200k/yr RemoteFull Time
Protocol Nine
Protocol Nine: Building AI-native security infrastructure for threat detection and response.
4+ YOE4+ years building backend or distributed systems; strong in Python, Go, Java, or TypeScript; experience operating production systems and building APIs/integrations.
Python, Go, Java, TypeScript, REST
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1w
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Backend Infrastructure Engineer
Palo Alto, California, United States
$165k-$180k/yr HybridFull Time
Vinci
Vinci: AI software for rapid hardware design and physics simulation.
8+ YOE8+ years software engineering experience focused on backend and infrastructure. Hands-on Terraform and major cloud experience, CI/CD (Jenkins), build systems (CMake,pip/uv), Python and C++ proficiency, production platform experience.
Terraform, GCP, AWS, Azure, Jenkins, CMake, pip, uv, Python, C++, Docker, Kubernetes, PyTorch, NumPy, CUDA
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1mo
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Backend Engineer
San Francisco, California, United States
$130k-$200k/yr OnsiteFull Time
Sandberg Goldberg Bernthal Family Foundation
Sandberg Goldberg Bernthal Family Foundation: Operates programs for women's empowerment and community resilience.
3+ YOE3+ years backend or full-stack engineering experience with data/analytics; strong Python (preferred) or Node.js/Ruby/Java, SQL and NoSQL skills; experience building data pipelines, defining metrics, A/B testing, and data visualization; bachelor's in CS/data field or equivalent.
Python, Node.js, Ruby, Java, SQL, NoSQL, RESTful APIs
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3mo
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Senior Backend Engineer - Virtual Guard
San Mateo, California, United States
$130k-$280k/yr OnsiteFull Time
Verkada
Verkada: Sells integrated AI-powered cloud physical security hardware and software.
5+ YOE5+ years backend engineering experience; distributed systems, event-driven architectures, scalable APIs; real-time data pipelines; cloud and edge; Go or Python; Kafka, Temporal, Postgres; strong ownership.
Go, Python, Kafka, Temporal, Postgres, Cloud
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1mo
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Sr. Backend Engineer
San Francisco, California, United States
$145k-$170k/yr HybridFull Time
LeapXpert
LeapXpert: Compliant enterprise communication platform for secure consumer messaging.
6+ YOE6+ years building backend/distributed systems, experience designing agentic runtimes and SDKs, multi-tenant isolation, async/concurrent patterns, secure API design, observability, and production-grade platform development.
Temporal, Claude Code, Codex, Gemini CLI, Go, Python, TypeScript/Node.js, Rust, Kubernetes, CI/CD, OpenTelemetry, Prometheus, Grafana, SQL, gRPC, Claude Managed Agents, Bedrock Agents, Google Agent Builder, Azure AI Services, Google ADK, Claude Agent SDK, OpenAI SDK, LangChain, CrewAI, AutoGen, MCP, Kafka, Neo4j
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1w
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Backend Developer
San Francisco, California, United States
RemoteFull Time
CareerSwift
CareerSwift: AI-powered recruitment and job search automation platform
3+ YOE3+ years backend development, proficiency in Python/Java/Node.js/Go/C#, API design (REST/GraphQL/event-driven), SQL/NoSQL knowledge, API security, Git, automated testing and deployment workflows.
Python, Java, Node.js, Go, C#, REST, GraphQL, SQL, NoSQL, Git, AWS, Azure, Google Cloud, Kubernetes
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3mo
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Engineer, Backend
San Mateo, California, United States
OnsiteFull Time
Bedrock Data
Bedrock Data: AI-native data security and governance platform for enterprise environments.
Backend engineer with experience designing scalable services; strong problem-solving; entrepreneurial mindset.
Golang, Python, Node, AWS, Neo4j, SQL
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2mo
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Semiotic Labs - Senior Backend Engineer
New York or San Francisco
RemoteFull Time
YieldNest
YieldNest: Liquid restaking protocol for risk-adjusted DeFi yields.
5+ YOE5+ years backend development in Python; async programming; deep PostgreSQL; multi-tenant data isolation; Redis; OpenTelemetry; AWS; strong system design and collaboration.
Python, FastAPI, Pydantic, Async SQLAlchemy, PostgreSQL, pgvector, Row-level security, Redis, OpenTelemetry, AWS, React, Vite
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2mo
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Senior Backend Engineer
San Francisco, California, United States
$175k-$275k/yr OnsiteFull Time
Hedra
Hedra: Builds artificial intelligence models for character-driven video generation.
5+ YOE5+ years backend development with Python, FastAPI/Pydantic; Kubernetes/EKS; relational databases; AWS stack; building scalable services.
Python, FastAPI, Pydantic, Kubernetes, EKS, PostgreSQL, Redis, S3, DynamoDB, AWS
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3w
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Backend Engineer - Oort
San Francisco or Golden or Toulouse
$140k-$190k/yr OnsiteFull Time
Loft Orbital
Loft Orbital: Deploy and operate satellite missions for organizations and governments.
Proficiency in Python and Docker, backend/API design and database interaction, experience with space mission technologies, strong communication and product mindset.
Python, Docker, Django, GraphQL, GCP, AWS, Kubernetes, PyTest, Jest, React Testing Library, Playwright, Cypress
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1mo
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Senior Backend Engineer, Ambient AI
Mountain View or San Francisco or New York City
$170k-$230k/yr OnsiteFull Time
Commure
Commure: AI-powered software platform for healthcare workflow and administrative automation.
Professional software development experience; strong backend skills with Python and web frameworks; experience with containers and cloud (Docker, Kubernetes); production systems, alerting, metrics, and SRE practices; leadership and customer-facing experience.
Python, Flask, Django, FastAPIs, Docker, Kubernetes, LLMs, EHRs
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2mo
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Backend Engineer
Mountain View, California, United States
HybridFull Time
Bespoke Labs
Bespoke Labs: Curating data and environments to train advanced AI agents.
Production systems, distributed infra, sandboxing; Python; cloud experience; collaboration with research teams; strong reliability mindset.
Python, Go, Rust, C++, Docker, Kubernetes, GCP, AWS, CLI
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2mo
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Backend Software Engineer
San Francisco, California, United States
$125k-$150k/yr OnsiteFull Time
Lumafield
Lumafield: Accessible industrial CT scanners and cloud-based analysis software
2+ YOEBachelor's degree in Engineering or related field; 2+ years Python backend experience with web frameworks; experience with large dataset processing; strong software engineering fundamentals; team collaboration; Linux, Docker, production deployments.
Python, Django, Django Rest Framework, Celery, AWS (EKS, S3, CloudFront), Docker, Kubernetes, Linux
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1d
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Senior Backend Engineer, Managed Kubernetes & Slurm
New York City or San Francisco or Seattle
$180k-$250k/yr HybridFull Time
Lightning AI
Lightning AI: Unified platform to build, train, and deploy AI models.
Significant experience building and operating production backend systems with Go or Python, deep Kubernetes or Slurm knowledge, distributed systems, networking, observability, CI/CD, and production incident response.
Go, Python, Kubernetes, Slurm, Terraform, Crossplane, Helm, Argo CD, Flux, Kustomize, gRPC
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1w
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Backend Engineer, AI Systems
Sunnyvale, California, United States
$177k-$195k/yr OnsiteFull Time
GFiber: An Alphabet providing fiber and webpass internet services to homes and businesses.
5+ YOEBachelor's or equivalent experience, 5+ years software development, Python, GCP, microservices, REST APIs, production support, and practical experience with LLMs/AI agents and RAG/MCP pipelines.
Python, RAG, Model Context Protocol (MCP), RESTful APIs, Google Kubernetes Engine (GKE), Cloud Run, Google Cloud Observability (Stackdriver), OpenTelemetry, Google Cloud Platform (GCP), AntiGravity, Claude, Cursor, Java, Kotlin
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