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253 quantitative developer jobs at 148 companies in Santa Clara, CA

1mo
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Quantitative Developer
Menlo Park or San Francisco
$180k-$280k/yr HybridFull Time
Poesis
Poesis: AI-native investment manager building foundation models for equity markets.
Strong Python (pandas, numpy, scipy, matplotlib), SQL, experience with coding agents (Claude Code, Codex), working with financial datasets, statistics/ML fundamentals, and a BS/MS/PhD in a quantitative field. Current US work authorization required.
Python, pandas, numpy, scipy, matplotlib, SQL, Claude Code, Codex, Bloomberg, CapIQ, FactSet, Refinitiv, git, Docker, Prefect, Airflow
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1w
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Senior Developer - Quantitative
Southlake or Chicago or San Francisco
$58-$67/hr OnsiteFull Time
Charles Schwab
Charles SchwabNYSE: SCHW: Financial services, brokerage, and investment management provider.
Bachelor's degree or equivalent, proficiency in Python, experience building AI/LLM solutions, quantitative technology familiarity, strong communication and problem-solving skills.
Python, GitHub, GitHub Actions, Confluence, JIRA, Bamboo, Gurobi, LangChain, LangGraph, LlamaIndex, Hugging Face Transformers, RAG
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1mo
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Junior Quantitative Analyst
Austin or Chicago or New York or Old Greenwich or San Francisco or West Palm Beach
$150k/yr OnsiteFull Time
WorldQuant
WorldQuant: Develops systematic investment strategies through quantitative research and data.
Undergraduate or advanced degree in a quantitative field; programming in Python and/or C++; Linux experience; strong problem-solving and quantitative skills; interest in financial data, machine learning, and data engineering.
Python, C++, Linux
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1mo
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Quantitative Biologist
Emeryville, California, United States
$150k-$200k/yr OnsiteFull Time
Arcadia Science
Arcadia Science: Translates evolutionary biology into novel therapeutics and research tools.
3+ YOEPh.D. or equivalent with 3+ years post-PhD scientific experience; expertise in statistically driven experimental design, image analysis, machine learning on biological data, Python/R proficiency, pipeline and software development, and direct bench experience.
Python, R
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3mo
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Quantitative Researcher - Model Scaling
San Francisco, California, United States
$144k-$187k/yr OnsiteFull Time
MSCI
MSCINYSE: MSCI: Provides critical decision support tools for the investment community.
PhD or MS in quantitative field; strong Python; AI tooling experience; AI/LLMs in workflows; data analysis with large-scale data; econometrics; independent; finance knowledge preferred.
Python, AI tooling, ML frameworks, Data infrastructure tools
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1w
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Quantitative Intelligence Analyst
San Francisco, California, United States
$198k-$320k/yr HybridFull Time
OpenAI
OpenAI: Develops artificial intelligence models and generative AI software services.
3+ YOE3+ years in quantitative intelligence or risk research, experience with statistical modeling and data mining, familiarity with trust & safety domains, and strong communication and critical thinking.
Python, SQL
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Quantitative Researcher for Risk and Research Engagement
Chicago or New York City or San Francisco
$150k-$180k/yr HybridFull Time
Comity
Comity: Provides a clearing platform for renewable energy transactions.
Strong quantitative background, experience building quantitative risk/portfolio models, performance attribution, portfolio optimization, strong Python skills with large datasets, and ability to partner with PMs and risk teams.
Python
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Staff Software Engineer, Quantitative Evaluations
Mountain View or San Francisco
$251k-$310k/yr HybridFull Time
Waymo
Waymo: Autonomous driving technology for ride-hailing and logistics.
4+ YOEBS in a quantitative field; 4-7 years experience; strong C++, Python, SQL skills; data analysis; building data pipelines; ML familiarity; strong coding standards.
C++, Python, SQL, Machine Learning, Data Processing, Statistics
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3mo
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Quantitative Researcher - Model Scaling
San Francisco, California, United States
$144k-$187k/yr OnsiteFull Time
MSCI
MSCINYSE: MSCI: Provides investment decision support tools and financial analytics.
MS/PhD in Finance, Statistics, Computer Science, Engineering; strong Python; experience with AI tooling; data infrastructure; econometrics; ability to drive projects independently; finance/risk modeling knowledge preferred.
Python, AI development tools, Large-scale data tooling, Econometrics software
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1mo
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Quantitative Research Associate - Systematic Portfolio Construction
Los Angeles or San Francisco or New York or California or United States
$159k-$255k/yr OnsiteFull Time
Capital Group
Capital Group: Providing active investment management and research-driven financial strategies
5+ YOE5+ years relevant experience in optimization and systematic portfolio construction; advanced degree preferred; expertise in Python/Julia/R and optimization software (Gurobi or Mosek); strong quantitative, econometrics and communication skills.
Python, Julia, R, Gurobi, Mosek
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4w
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Senior Quantitative UX Researcher, Search Growth Systems and App Foundations
Mountain View, California, United States
$159k-$231k/yr OnsiteFull Time
Google
GoogleNASDAQ: GOOGL: Provides online search, advertising, cloud computing, and consumer electronics.
6+ YOEBachelor's degree or equivalent and 6+ years product research experience; strong quantitative methods (A/B testing, surveys, log analysis), programming (Python, R, MATLAB, C++, Java, Go), and SQL; qualitative methods experience.
Python, R, MATLAB, C++, Java, Go, SQL
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3w
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Principal Machine Learning Engineer (Reconstruction / Quantitative Imaging)
San Francisco, California, United States
OnsiteFull Time
Midjourney
Midjourney: Independent research lab developing generative AI and medical imaging technology.
Strong applied ML experience with imaging or signal processing, ability to move between research prototypes and production systems, strong evaluation discipline, and experience applying ML to physics-based/inverse problems.
PiNNs, Neural Operators, Agentic-SciML, GPU, Kalman filtering
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1w
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UX Researcher, Quantitative
Bellevue or Menlo Park or Seattle or New York City or United States
$193k-$266k/yr HybridFull Time
Meta
MetaNASDAQ: META: Develops social networking platforms and virtual reality technologies.
13+ YOEExpertise in quantitative research: coding in R/SQL/Python, survey design, regressions/ANOVA/t-tests, extensive hands-on primary research, advanced degree plus multi-year experience.
R, SQL, Python
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3w
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Senior Staff Scienitst-Quantitative Modeling, AI & Pharmacometrics
San Francisco, California, United States
OnsiteFull Time
UCSF Health
UCSF Health: Academic medical center providing advanced patient care and research.
5+ YOEBachelor's in computational/data science or domain science with computational focus; 5+ years relevant experience; advanced pharmacometrics/MIDD knowledge; Python and/or R programming; experience with mechanistic, PK/PD, Bayesian or ML models; scientific leadership and communication skills.
Python, R
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1mo
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Group Leader - Senior Director, Quantitative Pharmacology and Pharmacometrics - Cardiometabolic
Rahway or Boston or San Francisco or West Point
$210k-$331k/yr HybridFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Produces prescription medicines, vaccines, and animal health products.
10+ YOEDoctorate (Ph.D./PharmD) with 10+ years drug development/regulatory experience; leadership experience; expertise in translational PK/PD, pharmacometrics, regulatory strategy, and cross-functional collaboration.
NONMEM, R, Monolix, Phoenix
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2mo
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Senior Software Engineer, Map Platform
Mountain View, California, United States
$194k-$291k/yr OnsiteFull Time
Nuro
Nuro: Builds autonomous driving software and electric delivery robots.
BS in CS/Robotics or quantitative field; experience with distributed systems, data storage/processing, C++/Python, multithreading, and performance tuning; strong problem-solving; able to develop and debug production code.
C++, Python
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Senior Deep Learning Engineer - Perception
San Jose or Israel
OnsiteFull Time
Imagry
Imagry: Mapless autonomous driving software for vehicle manufacturers.
3+ YOEMSc (or equivalent experience) in quantitative field, 3+ years developing deep learning algorithms, strong computer vision and math skills, PyTorch and Python proficiency, English fluency, eligible to work in the US.
PyTorch, Python, Linux, git, C++
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2mo
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Senior Developer Relations Manager, Capital Markets
New York or Santa Clara or California or New York
$224k-$431k/yr HybridFull Time
NVIDIA
NVIDIANASDAQ: NVDA: Designs graphics processing units and artificial intelligence hardware.
12+ YOEBachelor's or higher in CS/Engineering (or equivalent experience); 12+ years in tech or finance with 8+ years in capital markets; deep technical expertise in HPC, quantitative finance, AI/ML; proven developer relations and partnership experience; strong communication.
CUDA, CUDA-X, AI frameworks, SDKs
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3d
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Computational Postdoctoral Fellow (Quantitative Modeling Group)
Emeryville, California, United States
$96k-$107k/yr OnsiteFull Time
Lawrence Berkeley National Laboratory
Lawrence Berkeley National Laboratory: Conducts scientific research to address global challenges.
PhD (recent within 1–2 years) in related quantitative fields, programming in Python, Linux experience, strong math and communication skills, <3 years postdoctoral experience preferred.
Python, Linux
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3mo
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Senior Manager, Nodal Markets & Quantitative Analysis
Houston or Berkeley
HybridFull Time
TotalEnergies
TotalEnergiesEuronext Paris: TTE: Produces and markets fuels, natural gas, and low-carbon electricity.
10+ YOELead nodal markets and quantitative analysis; manage team; develop models; collaborate with cross-functional teams; 10+ years experience in energy markets.
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