Dyne TherapeuticsNASDAQ: DYN: Developing therapeutics for genetically driven neuromuscular diseases.
2+ YOEPhD in Chemistry or related field with 2+ years experience, or MSc with 8+ years in biotech/life sciences; hands-on oligonucleotide synthesis and purification; familiarity with conjugation and analytical assays.
Prime MedicineNASDAQ: PRME: Developing precision gene editing therapies to treat genetic diseases.
0+ YOEExpertise in oligonucleotide and phosphoramidite chemistry, hands-on RNA synthesis and purification, analytical characterization experience, strong troubleshooting and collaboration skills.
MerMade 12, Dr. Oligo, HPLC, UPLC, LC-MS (Orbitrap), UV-Vis spectroscopy
ModernaNasdaq: MRNA: Develops and manufactures messenger RNA medicines and vaccines.
2+ YOEMS in biochemistry/chemical biology/related field with 2+ years experience; experience with RNA, cell culture, sequencing and analytical methods; must be authorized to work in the US (no sponsorship).
RT/qPCR, chromatography, mass spectrometry, Next Generation Sequencing
Research Associate - RNA Synthesis Platform Development
Waltham, Massachusetts, United States
$65k-$93k/yrOnsiteFull Time
SanofiEuronext Paris: SAN: Researches, develops, and manufactures medicines and vaccines globally.
1+ YOEBachelor's in biochemistry/molecular biology/chemical engineering or related; 1+ year industrial lab experience; experience with RNA synthesis, IVT, enzymatic process development; strong experimental design, quantitative analysis, and English communication.
Hamilton Vantage, Venus, qPCR, ELISA, Capillary electrophoresis, Spectrophotometry
Sarepta TherapeuticsNASDAQ: SRPT: Develops precision genetic medicines for rare diseases.
12+ YOEPhD with 12+ years or MS with 15+ years in chemistry/chemical engineering or related industry; demonstrated RNA therapeutics and GMP/process scale-up experience; leadership, regulatory and tech transfer expertise; travel ~15%; U.S. work authorization required.
Thermo Fisher ScientificNYSE: TMO: Sells equipment and chemicals for scientific research and healthcare.
2+ YOEBachelor's in a lab science (or equivalent), ~2+ years relevant experience, proficiency with ddPCR/qPCR and sequencing workflows, data analysis using R/GraphPad/JMP, and ability to operate sequencing and digital PCR instruments.
digital PCR, qPCR, ddPCR, NanoString nCounter, Oxford Nanopore, R, GraphPad Prism, JMP, Microsoft Excel, Microsoft PowerPoint, Microsoft Word, NextSeq 2000, NovaSeq X, PromethION 24, NanoString nCounter Prep Station/Digital Analyzer
New England Biolabs: Produces enzymes and reagents for life science research applications.
Ph.D. in biochemistry or related field; experience with enzymatic and next-generation sequencing assays (Illumina, ONT); publication record; strong analytical, communication, and problem-solving skills; ability to work independently and collaboratively.
Bristol Myers SquibbNew York Stock Exchange: BMY: Develops and distributes innovative medicines for serious diseases.
3+ YOEDevelop and execute bench-scale DNA and mRNA manufacturing for preclinical use; cloning, in vitro transcription, purification, analytical methods, and troubleshooting; B.S./M.S./Ph.D. in life sciences with relevant industry or academic experience.
qPCR, sequencing, capillary gel electrophoresis (CGE), automated liquid handlers
3+ YOEDevelop and execute bench-scale DNA and mRNA production for preclinical use; hands-on plasmid DNA and in vitro transcription experience; 3+ years relevant experience; laboratory analytical skills and automated liquid handler experience preferred.
Eli Lilly and CompanyNYSE: LLY: Researches and manufactures medicines for human health.
10+ YOEMS with 10+ years or BS with 15+ years pharma/biotech lab automation experience; deep liquid handling (Hamilton STAR), NGS workflows, integrated workcells, EMR/ELN/LIMS integration, Python scripting, project leadership, and vendor collaboration.
Hamilton STAR, Biosero Green Button Go, Benchling, ELN, LIMS, Python
RNA-LNP Process Development Lab Coordinator - Group Leader
Boston, Massachusetts, United States
$100k-$115k/yrOnsiteFull Time
Eurofins ScientificEuronext Paris: ERF: Global provider of analytical testing and laboratory services.
5+ YOEB.S. with 5+ years, M.S. with 3+ years, or PhD with 2+ years in relevant pharmaceutical, CRO, or biotech experience; supervisory experience and nucleic acid process development knowledge required.
Electronic Lab Notebook (ELN), Agilent HPLC, AKTA Avant, Capillary Gel Electrophoresis (CGE), ELISA
Alnylam PharmaceuticalsNASDAQ: ALNY: Develops RNAi therapeutics to treat rare and common diseases.
PhD in biology/biomedical sciences required; expertise in CNS/motor neuron disease biology, in vitro and in vivo models, RNA/protein quantification, high-content imaging, single-cell RNA-seq; strong communication and leadership.
SecureBio: Developing technology and policy to prevent catastrophic pandemics.
4+ YOEMS or PhD with 4+ years laboratory experience (exceptional BS considered); hands-on NGS and environmental RNA experience; autonomy, experimental design, and communication skills.
Merck KGaA, Darmstadt, GermanyFrankfurt Stock Exchange: MRK: A science and technology in healthcare, life sciences, and electronics.
3+ YOERequires a PhD in chemistry, chemical engineering, science, or engineering and 3+ years in oligonucleotides; preferred bioinformatics, genomic dataset, RNA sequencing, collaboration, and communication experience.
Mass General Brigham: Provides integrated medical care, research, and clinical training services.
PhD in neuroscience, molecular biology, genetics, or related field; experience with mouse models, gene editing (CRISPR) and RNA biology; in vivo studies; strong communication and collaboration.
CRISPR/Cas, RNA biology, RT-PCR, qRT-PCR, Western blot, molecular biology, cell culture, genomic sequencing, immunohistochemistry, in vivo mouse models, histology
Cambridge or Waltham or Rockville or San Francisco
$121k-$202k/yrOnsiteFull Time
GSKLondon Stock Exchange: GSK: Develops and manufactures innovative vaccines and specialty medicines.
3+ YOEPhD with 3+ years in chemistry/oligonucleotide synthesis; 2+ years industry experience in synthetic chemistry; expertise in SPOS oligo synthesis and RNA therapeutics; leadership and mentorship experience.
Research Scientist I or II, Oligonucleotide Chemistry
Cambridge, Massachusetts, United States
$67k-$124k/yrHybridFull Time
NovartisSIX Swiss Exchange, NYSE: NOVN, NVS: A pharmaceutical developing medicines and advancing therapeutic innovation.
1+ YOEBS or MS in chemistry or related science; 1–3 years of laboratory experience; hands-on oligonucleotide synthesis, purification, characterization, chromatography, mass spectrometry, and RNA therapeutics knowledge.
DNA synthesizers, RNA synthesizers, chromatography, mass spectrometry, electronic laboratory notebook systems
Wave Life SciencesNasdaq: WVE: Designing and developing RNA medicines for genetic diseases.
3+ YOEPh.D. (3+ yrs) or M.S. (6+ yrs) in a related discipline; experience in DMPK/bioanalysis for RNA modalities; proficiency with PK software and data analysis; strong communication and teamwork skills.