318 scientific computing jobs at 192 companies in United States

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Scientific Computing Software Engineer
Northridge, California, United States
$90k-$165k/yr OnsiteFull Time
Areté
Areté: Develops advanced sensing and signal processing solutions for national security.
College degree in a scientific discipline or CS with focus on scientific computing; strong Python (numpy, scipy, pandas) and C/C++ skills; ability to obtain TS/SCI clearance; excellent communication and algorithm assessment skills.
Python, numpy, scipy, pandas, C, C++, Linux, CUDA, MPI, OpenMP
1w
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Scientific Computing/Advanced Imaging Lead
Rockville, Maryland, United States
OnsiteFull Time
Nextonic Solutions
Nextonic Solutions: Provides scientific and technology development services to federal agencies.
Evaluate and integrate emerging scientific and computational technologies, develop prototypes and pipelines, perform testing and documentation, and lead Agile pre-production to transition activities.
Agile
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Scientific Computing & Geospatial Engineer
Tuscaloosa, Alabama, United States
$85k-$120k/yr RemoteFull Time
Lynker
Lynker: Science and technology solutions for government and environmental agencies.
3+ YOEBachelor's in CS, geospatial science, hydrology or related; 3+ years software development; strong Python (numpy, pandas, xarray, geopandas); GDAL; AWS (S3, EC2, batch); Docker, CI/CD; ability to design cloud-native geospatial pipelines.
Python, numpy, pandas, xarray, geopandas, GDAL, Parquet, Zarr, NetCDF, S3, EC2, batch, Docker, CI/CD, Rust, Terraform, AWS CDK, HPC
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Scientific Computing and Data Management SME
Washington or Virginia or United States
RemoteFull Time
ECS
ECSNYSE: ASGN: Provides advanced technology and engineering services to government agencies.
8+ YOEBachelor's in CS or related, active Public Trust clearance, 8+ years supporting IT/HPC environments, experience with scientific instrumentation, Windows/MacOS/Linux and scripting, FISMA knowledge, reside in DC metro, travel CONUS as needed.
Linux, Windows, MacOS, HPC, PMI, Lean IT, Agile, DevOps, ITIL
19h
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High Performance and Scientific Computing Fellow
Austin, Texas, United States
HybridFull Time
AMD
AMDNASDAQ: AMD: Designs and manufactures computer processors and graphics technology.
Deep expertise in mathematical algorithms, floating point precision, GPU performance analysis, distributed systems, software architecture; strong experience with C/C++, C, Fortran, HIP/CUDA/OpenCL, MPI/SHMEM; technical leadership and mentorship; advanced degrees preferred.
ROCm, C++, C, Fortran, HIP, CUDA, OpenCL, MPI, SHMEM, assembly
2mo
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Associate Director, Scientific Computing and AI Engineer
South San Francisco, California, United States
$159k-$207k/yr OnsiteAll Commitments Available
Denali Therapeutics
Denali TherapeuticsNASDAQ: DNLI: Developing therapies to treat neurodegenerative and lysosomal storage diseases.
10+ YOE10-12 years in platform engineering/infrastructure with senior IC; expertise in HPC, cloud, AI/ML; IaC/CI/CD; Python; regulated biotech experience; leadership experience.
Slurm, LSF, GPU/CUDA, Cloud platforms, MLOps, LangChain, LangGraph, AutoGen, Python, Terraform, CI/CD
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Senior Scientific Developer
United States or North America
RemoteFull Time
Deep Origin
Deep Origin: Platform for scientific simulation and drug discovery research.
MSc/PhD or equivalent experience in chemistry/biology/computational fields; deep domain knowledge in medicinal chemistry/cheminformatics/structural biology/molecular simulation; production-quality Python and Docker skills; experience deploying scientific workflows.
Python, PyPI, uv, conda, pixi, ruff, ty, Marimo, Docker, Claude Code, Cursor, Julia, Kubernetes, Argo Workflows, Knative, TypeScript, JavaScript, PostgreSQL, RDKit
2mo
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QBID Quantum Computing SME
Arlington, Virginia, United States
$192k-$320k/yr OnsiteFull Time
American Systems
American Systems: Providing strategic engineering and IT solutions for government programs.
15+ YOE15+ years in scientific/ RDT&E sectors; PhD in hard science or engineering; demonstrated quantum computing expertise; DoW RDT&E experience; TS/SCI clearance; US citizenship.
Quantum computing
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HPC Scientific Software Engineer (IT@JH Research Computing)
Baltimore, Maryland, United States
$86k-$150k/yr RemoteFull Time
Johns Hopkins University
Johns Hopkins University: A private research university providing higher education and clinical healthcare.
5+ YOEMaster's in CS or related, 5+ years HPC user support and software deployment experience, hands-on with SLURM, Python/Perl/C/C++/Shell, Linux, containerization, Spack/EasyBuild/CMake, performance optimization and user support.
SLURM, Ansible, XDMoD, Coldfront, Open OnDemand, CryoSPARC Live, SBGrid, NVIDIA, Intel, MATLAB, CUDA, DNN, TensorRT, Intel Compilers, CMake, Make, EasyBuild, Spack, Lua, Python, Perl, C/C++, Shell
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Scientific Programmer Analyst V
Greenbelt, Maryland, United States
$140k-$160k/yr HybridFull Time
Science and Technology Corporation
Science and Technology Corporation: Provides scientific, engineering, and technical services to government agencies.
15+ YOEPhD (or Master's with additional experience) and ~15+ years in scientific software/HPC, demonstrated technical leadership, expertise in modeling frameworks and high-performance computing, U.S. citizenship or permanent residency.
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Senior AI/ML Engineer: Python & Scientific Computing
San Francisco or New York City or United States
$175k-$250k/yr HybridFull Time
Swayable
Swayable: Measures message impact and public opinion using causal AI.
5+ YOE5+ years building scientific or quantitative data‑intensive software; expertise in scientific Python stack, object‑oriented and test‑driven development, vectorized code, machine learning, and distributed/parallel computing.
Python, NumPy, SciPy, scikit-learn, Pandas, Celery, Flask, JavaScript, Vue.js, Node.js, MongoDB, GraphQL, Linux
3w
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Scientific Director, Computational Chemistry
San Diego, California, United States
$218k-$298k/yr OnsiteFull Time
Neurocrine Biosciences
Neurocrine BiosciencesNASDAQ: NBIX: Develops pharmaceuticals for neurological, endocrine, and psychiatric disorders.
8+ YOEAdvanced degree plus 8+–12+ years computational chemistry drug discovery experience, leadership experience, expertise in molecular modeling, SBDD, cheminformatics, AI/ML, cloud/HPC workflows, and experience integrating computational methods into multidisciplinary teams.
Knime, Schrödinger, OpenEye, MOE
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Scientific Product Specialist, ADMET Predictor
United States
$100k-$120k/yr RemoteFull Time
Simulations Plus
Simulations PlusNASDAQ: SLP: Develops biosimulation software and consulting for drug development.
2+ YOE2+ years in medicinal/computational chemistry, cheminformatics, or pharmaceutical sciences; knowledge of ADMET and regulatory guidelines; proficiency in Python, R, or KNIME; presentation, training, and scientific writing experience.
ADMET Predictor, Python, R, KNIME, RDKit, Schrödinger, MOE
2w
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Senior Scientific Advisor
Springfield, Virginia, United States
$150k-$170k/yr OnsiteFull Time
Core4ce
Core4ce: Provider of data-driven national security and defense technology solutions.
Active TS-SCI with CI poly, bachelor's degree in engineering/physical sciences/computer science, deep space/GEOINT technical expertise, systems analysis, trade studies, and stakeholder coordination.
1w
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Scientific Consultant - Part-Time
State College, Pennsylvania, United States
OnsitePart Time
Penn State University
Penn State University: Provides higher education and conducts extensive academic research programs.
Current Penn State graduate student with expertise in computational biology/bioinformatics or related data-intensive discipline; proficiency with computational and data science methods; attention to detail and ability to learn new tools.
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Software Engineer, Scientific Computing
Redwood City, California, United States
$130k-$190k/yr OnsiteFull Time
Vorticity
Vorticity: Developing specialized silicon to accelerate scientific computing beyond GPUs.
Bachelor's in math/physics/CS/engineering, strong Python skills, solid foundation in math/physics/CS, ability to work across abstraction levels and disciplines.
Python, CUDA
3mo
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Scientific Analyst II
Tucson, Arizona, United States
$59k-$74k/yr HybridFull Time
University of Arizona
University of Arizona: Public research university providing higher education and academic programs.
3+ YOEMaster's degree in Data Science, Biostatistics, Bioinformatics, Computational Biology, Computer Science, or related field; at least 3 years of relevant work experience.
Python, R, scikit-learn, TensorFlow, PyTorch, XGBoost, SQL
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Scientific Instr Technician
Denton, Texas, United States
OnsiteFull Time
University of North Texas System
University of North Texas System: Provides comprehensive higher education and research in North Texas.
3+ YOEAssociate's degree and 3 years related experience (or equivalent). Maintain, construct, repair, and troubleshoot electronic, electromechanical, and mechanical lab equipment; manage inventory, computing needs, and supervise part-time staff.
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HPC Scientific Support Engineer
Berkeley, California, United States
$139k-$268k/yr HybridFull Time
Lawrence Berkeley National Laboratory
Lawrence Berkeley National Laboratory: Conducts scientific research to address global challenges.
8+ YOE8+ years related experience with a Bachelor's (CSE3) or 12+ years (CSE4); 2+ years using HPC systems; expertise in high-performance scientific computing including at least four of Linux/Unix, Fortran, C/C++, MPI, OpenMP, OpenACC, CUDA, shell scripting, Python, parallel algorithms, debuggers, performance tools, containers; strong communication and t...
Linux/Unix, Fortran, C/C++, MPI, OpenMP, OpenACC, CUDA, shell scripting, Python, debuggers, performance tools, containers, REST, JavaScript, SQL
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Scientific and Laboratory Informatics Manager
Orlando or Milwaukee or Dallas or Columbus or Kirkland or Cincinnati or New York City or Cleveland or Oklahoma City or Austin or Albany or Chicago or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Mountain View or Scottsdale or San Francisco or Morristown or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
$80k-$294k/yr OnsiteFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
6+ YOE6+ years in scientific and laboratory informatics, bachelor’s degree in life science, laboratory science, computer science or engineering, consulting experience preferred, willingness to travel up to 50% to client sites.