11 scientific software engineer jobs at 9 companies in New York City, NY

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Scientific Software Developer
New York, New York, United States
$250k-$600k/yr HybridFull Time
D. E. Shaw Research
D. E. Shaw Research: Developing custom supercomputers for biomolecular simulation and drug discovery.
Develop scientific software and workflows for drug discovery, including cheminformatics tools, virtual screening/docking, molecule design, scalable chemical databases, modeling, analysis, and visualization.
3w
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Software Engineer
New York, New York, United States
$130k-$150k/yr HybridFull Time
Man Group
Man GroupLondon Stock Exchange: EMG: Global alternative investment management firm serving institutional clients.
Experienced software engineer with strong Python on Linux, scientific stack (NumPy/SciPy/Pandas/scikit-learn), web/dev skills, AI/LLM experience, Kubernetes and Airflow familiarity; strong analytic and communication skills.
Python, Linux, NumPy, SciPy, Pandas, scikit-learn, Kubernetes, Airflow, C#, .NET, React, Streamlit, FastAPI, Django, ArcticDB, Microsoft Excel
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Software Engineer
New York, New York, United States
$150k-$175k/yr OnsiteFull Time
Garda Capital Partners: Provides fixed income investment strategies for institutional investors.
4+ YOE4+ years object-oriented development with C# and Python, relational DB/SQL experience, familiarity with Python scientific stack, Docker/Kubernetes, gRPC, and risk or capital markets knowledge preferred.
C#, Python, gRPC, NumPy, pandas, duckdb, Parquet, Oracle, Postgres, Docker, Kubernetes, JavaScript, React
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Software Engineer
New York City, New York, United States
$130k-$150k/yr HybridFull Time
Man Group
Man GroupLondon Stock Exchange: EMG: Global alternative investment management and systematic trading services.
Strong Python and Linux experience, data pipeline and web development skills, familiarity with scientific libraries (NumPy/SciPy/Pandas), Kubernetes and Airflow, experience with AI/LLM tools, strong analytical and communication skills; degree in computing/math preferred.
Python, Linux, NumPy, SciPy, Pandas, scikit-learn, React, Streamlit, FastAPI, Django, ArcticDB, Kubernetes, C#, .NET, Airflow, Microsoft Excel, LLM
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Senior AI/ML Engineer: Python & Scientific Computing
San Francisco or New York City or United States
$175k-$250k/yr HybridFull Time
Swayable
Swayable: Measures message impact and public opinion using causal AI.
5+ YOE5+ years building scientific or quantitative data‑intensive software; expertise in scientific Python stack, object‑oriented and test‑driven development, vectorized code, machine learning, and distributed/parallel computing.
Python, NumPy, SciPy, scikit-learn, Pandas, Celery, Flask, JavaScript, Vue.js, Node.js, MongoDB, GraphQL, Linux
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Manager - IT Lab Operations & Scientific Systems
Beerse or Raritan or Spring House or Malvern
HybridFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Develops and manufactures pharmaceutical drugs and medical devices.
10+ YOERequires 10+ years of life sciences IT platform or scientific systems experience and a bachelor's or master's degree or equivalent experience in software engineering, computer science, chemistry, biochemistry, or chemical engineering.
LIMS, ELN, SDMS, Windows 11, Claude, GitHub Copilot, ChatGPT
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Senior Plasma Control Engineer
Kearny, New Jersey, United States
$120k-$160k/yr OnsiteFull Time
Thea Energy
Thea Energy: Developing nuclear fusion reactors using planar coil stellarator technology.
3+ YOEBS or MS in EE/CS/Physics/Applied Math, 3+ years developing control algorithms or real-time scientific software, strong Python/MATLAB/C++ skills, ML tooling experience, familiarity with control methods, ability to lift up to 50 lbs and work occasional nights/weekends.
Python, MATLAB, C++, PyTorch, TensorFlow, JAX, Jupyter, MDSplus, EPICS, HDF5, InfluxDB, OPC UA, Kafka, ZeroMQ, Git, Docker, MLflow, CI, MATLAB Simulink, Modelica, FMI, ONNX Runtime, TensorRT
4d
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Senior AI/ML Engineer - Research Data AI and Predictive Modeling (Vaccine R&D)
Pearl River, New York, United States
$139k-$232k/yr HybridFull Time
Pfizer
PfizerNYSE: PFE: Develops and manufactures vaccines and medicines for global healthcare
4+ YOEPhD in a relevant technical discipline, or master's degree plus 4 years of applied AI/ML experience; expertise in Python, AI/ML frameworks, data architecture, scientific datasets, and cross-functional technical leadership.
Python, PyTorch, TensorFlow, FAIR
6d
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Head of Regulatory
San Mateo or New York City or Boston or Salt Lake City
HybridFull Time
Overjet
Overjet: AI platform for dental diagnostics and practice management.
7+ YOERequires 7+ years in medical device regulatory affairs, 2+ years with FDA software as a medical device, global submissions experience, regulatory framework expertise, and a scientific or engineering bachelor's degree.
FDA 510(k), De Novo, Health Canada Medical Device License (MDL), EU MDR, UK MHRA, Australian TGA, 21 CFR Part 820, Software as a Medical Device (SaMD), ISO 13485, ISO 14971, IEC 62304, ISO 27001, HIPAA, GDPR
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Physical Scientist
Norman or College Park or Kansas City or Bohemia
$106k-$163k/yr OnsiteFull Time
National Oceanic and Atmospheric Administration
National Oceanic and Atmospheric Administration: United States agency for weather, oceanic, and atmospheric monitoring.
1+ YOEDegree in physical science, engineering, or mathematics with 24 semester hours in relevant science, plus one year of GS-12-equivalent specialized experience in weather data, Linux software, and scientific collaboration.
Linux, High-Performance Computing (HPC), Linux Virtual Machines (VM), USA Hire, USAJOBS, Microsoft Resume Builder
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Data Science and Engineering Manager
New York or California or Ohio or North Dakota or Washington or Wyoming
$185k-$225k/yr HybridFull Time
Child Mind Institute
Child Mind Institute: Clinical care and research for children's mental health.
8+ YOEMaster's required; 8+ years technical project management and data/ML/software experience; 5+ years scientific programming (Python/R, MATLAB) and PM tools (Notion, Jira, Kanban); experience managing cross-functional teams.
Notion, Jira, Kanban, Python, R, MATLAB, Tidyverse, SciPy, scikit-learn, Polars, PyTorch