151 scientific software engineer jobs at 84 companies in United States

PromotedHiringCafe
Founding Full-stack / Product Engineer
Cupertino, CA, US
$130k-$300k/yr On-SiteFull Time
HiringCafe
HiringCafe: Building a 100× better job search engine to take on Indeed and LinkedIn.
Help us build a 100× better job search engine. We need a full-stack engineer with great taste, sharp fundamentals, and a track record of shipping polished product on React/Next.js plus a real backend (Firebase, Elasticsearch, Redis, Stripe).
React, Next.js, TypeScript, Firebase, Elasticsearch, Redis, Stripe
1mo
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Scientific Software Developer
New York, New York, United States
$250k-$600k/yr HybridFull Time
D. E. Shaw Research
D. E. Shaw Research: Developing custom supercomputers for biomolecular simulation and drug discovery.
Develop scientific software and workflows for drug discovery, including cheminformatics tools, virtual screening/docking, molecule design, scalable chemical databases, modeling, analysis, and visualization.
1mo
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Scientific Software Engineer, AI Simulation
United States
$122k-$228k/yr RemoteFull Time
SandboxAQ
SandboxAQ: Develops AI and quantum technology for cybersecurity and science.
5+ YOE5+ years in software development; strong Python; ML with PyTorch; UNIX/Linux, Git; experience with scientific libraries; ability to build production-grade scientific software.
Python, NumPy, PyTorch, Git, Unix/Linux, Containerization, Cloud
1d
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Scientific Software Engineer
Broomfield or Fort Collins
$126k-$167k/yr OnsiteFull Time
Anduril Industries
Anduril Industries: Defense technology building autonomous military hardware and software.
2+ YOEBachelor's in CS/Engineering/Math/Physics (or equivalent), 2+ years relevant experience, strong C++ and Python skills, solid math foundation, software engineering fundamentals, and ability to obtain Top Secret/SCI clearance.
C++, Python, SQL, NoSQL, JavaScript, React, Node.js, MATLAB, Simulink
1mo
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Scientific Software Developer
Houston, Texas, United States
HybridFull Time
Viridien
ViridienEuronext Paris: VIRI: Provides geoscience technology and digital Earth data solutions.
5+ YOEMaster's degree in related field or 5 years scientific programming; fluency in C/C++, Fortran preferred; UNIX/POSIX, MPI, CUDA, debugging/profiling/optimization, HPC experience, full development lifecycle, strong communication.
C/C++, Fortran, UNIX, POSIX, MPI, CUDA, Python, Perforce, SQL
1mo
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Scientific Software Developer
Houston, Texas, United States
HybridFull Time
Viridien
ViridienEuronext Paris: VIRI: Provides geoscientific data, imaging services, and seismic exploration equipment.
5+ YOEMaster's degree in a quantitative field or 5+ years scientific programming, fluency in C/C++ (Fortran preferred), UNIX/POSIX, MPI/CUDA, debugging/profiling/optimization, HPC experience, full development lifecycle experience, strong communication skills.
C/C++, Fortran, UNIX, POSIX, MPI, CUDA, Python, ML toolbox, Perforce, SQL
2mo
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Scientific Software Developer (DC, NoVA)
Tysons, Virginia, United States
OnsiteFull Time
Stellar Science
Stellar Science: Scientific software for advanced physics-based modeling and simulation.
Ph.D., M.S., or B.S. in a scientific or engineering field; strong C++ OO design; substantial software development; modern C++20/23; U.S. citizen; background check; government-site work.
C++, C++20, C++23, TypeScript, Python, Java, Boost, Eigen, Linux, Windows, Mac, OpenGL, OpenSceneGraph, WebGL, Qt, Java Swing, Material UI, OpenMP, MPI, CUDA
1mo
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Scientific Computing Software Engineer
Northridge, California, United States
$90k-$165k/yr OnsiteFull Time
Areté
Areté: Develops advanced sensing and signal processing solutions for national security.
College degree in a scientific discipline or CS with focus on scientific computing; strong Python (numpy, scipy, pandas) and C/C++ skills; ability to obtain TS/SCI clearance; excellent communication and algorithm assessment skills.
Python, numpy, scipy, pandas, C, C++, Linux, CUDA, MPI, OpenMP
2mo
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Scientific Software Engineer (Radiology)
Baltimore, Maryland, United States
$73k-$128k/yr OnsiteFull Time
Johns Hopkins University
Johns Hopkins University: A private research university providing higher education and clinical healthcare.
5+ YOEBachelor's in a related field and 5+ years' related experience; strong technical skills across full software lifecycle including requirements analysis, design, development, testing, implementation, documentation, and mentoring.
1mo
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Senior Scientific Software Developer – Bioimage Informatics
Memphis, Tennessee, United States
$86k-$155k/yr OnsiteFull Time
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital: Pediatric research hospital treating children with catastrophic diseases.
4+ YOEBachelor's in CS/data/info science or related, 4+ years IT/software development experience, strong proficiency in Java, Python, JavaScript, RESTful APIs, PostgreSQL, Docker, Maven, Git, SDLC and CI/CD, experience productionizing scientific/image-analysis software.
NumPy, SciPy, scikit-image, Dask, Zarr, OME-Zarr/NGFF, Bio-Formats, OMERO, napari, ImageJ/Fiji, Python, Java, JavaScript, Spring, Node.js, RESTful APIs, PostgreSQL, Docker, Maven, Git, Model Context Protocol (MCP)
2mo
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HP100 Senior Scientific Software Developer
Greenbelt, Maryland, United States
OnsiteFull Time
ADNET Systems
ADNET Systems: Provider of information systems and scientific research services to government agencies.
10+ YOESenior software developer with 10 years of scientific programming; Linux; languages: IDL, HTML, Fortran, C, Java, JavaScript, Python; able to obtain Tier 1 background investigation; US citizenship or permanent residency.
IDL, Fortran, C, Java, JavaScript, Python, HTML, Linux, Git
1w
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Scientific Software Engineer - Full Stack
Emeryville, California, United States
$160k-$195k/yr OnsiteFull Time
Arcadia Science
Arcadia Science: Translates evolutionary biology into novel therapeutics and research tools.
Experience building production software, proficiency in Python and TypeScript, data pipeline and AI/LLM experience, strong product instincts and ability to partner with bench scientists.
Python, TypeScript, LLMs, AutoOpenRaman
2w
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Scientific Software Engineer - AMO Simulations
Boston, Massachusetts, United States
OnsiteFull Time
QuEra Computing
QuEra Computing: Develops and operates neutral-atom quantum computing systems.
Advanced degree or equivalent experience in physics, math, CS or related; strong background in quantum/AMO physics and numerical simulation; programming in Python/Julia/C++/Rust; familiarity with numerical linear algebra and scientific software practices.
Python, Julia, C++, Rust, QuantumOptics.jl, QuTiP, SciPy, NumPy, ITensor, CUDA, MPI
2mo
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Scientific Software Developer - Affinity
Santa Fe or Boston
OnsiteFull Time
Cadence Design Systems
Cadence Design SystemsNASDAQ: CDNS: Develops computational software and hardware for electronic system design.
3+ YOEPhD with postdoc; 3+ yrs Python; 3+ yrs Molecular Dynamics and free energy calculations; computational chemistry methods development and validation.
Python, Molecular Dynamics, Computational Chemistry Tools
2mo
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Scientific Software Developer - Affinity
Santa Fe or Boston
HybridFull Time
OpenEye
OpenEyeNASDAQ: CDNS: Molecular modeling and simulation software for drug discovery.
3+ YOEPhD with postdoc in structure-based ligand design; 3+ years in Python; 3+ years in Molecular Dynamics and Free Energy Calculations; team-oriented with strong communication; ability to learn new methods.
Python, C++, Molecular Dynamics, Free Energy Calculations, Computational Chemistry
3mo
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Senior Scientific Software Developer – Bioimage Informatics
Memphis, Tennessee, United States
$86k-$155k/yr OnsiteFull Time
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital: A pediatric treatment and research hospital for childhood diseases.
4+ YOEBachelor's in CS/data/information/business required; 4+ years software development experience; strong proficiency in Java, Python, JavaScript; experience with PostgreSQL, Docker, Maven, Git, RESTful APIs, CI/CD; familiarity with bioimaging tools preferred.
Python, NumPy, SciPy, scikit-image, Dask, Zarr, OME-Zarr/NGFF, Bio-Formats, OMERO, napari, ImageJ/Fiji, Java, JavaScript, Spring, Node.js, RESTful APIs, PostgreSQL, Docker, Maven, Git, Model Context Protocol (MCP), CI/CD
3mo
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Software Engineer, Scientific Models
San Francisco, California, United States
$173k-$234k/yr HybridFull Time
Benchling
Benchling: Cloud platform for biotechnology research and development.
3+ YOE3+ years software engineering or equivalent research experience; backend systems and infrastructure for model training or inference; strong analytical; collaborative; thrives in a fast-paced environment.
2w
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Senior Scientific Developer
United States or North America
RemoteFull Time
Deep Origin
Deep Origin: Platform for scientific simulation and drug discovery research.
MSc/PhD or equivalent experience in chemistry/biology/computational fields; deep domain knowledge in medicinal chemistry/cheminformatics/structural biology/molecular simulation; production-quality Python and Docker skills; experience deploying scientific workflows.
Python, PyPI, uv, conda, pixi, ruff, ty, Marimo, Docker, Claude Code, Cursor, Julia, Kubernetes, Argo Workflows, Knative, TypeScript, JavaScript, PostgreSQL, RDKit
2mo
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SuccessFactors Recruiting: Scientific Software Engineer (Radiology) (120969)
United States or Maryland
$73k-$128k/yr OnsiteFull Time
Johns Hopkins University
Johns Hopkins University: Private research university providing higher education and global research.
5+ YOEBachelor's degree in a technical field; 5+ years of related experience; strong analytical, development, and documentation skills.
1w
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Software Engineer, Scientific Computing
Redwood City, California, United States
$130k-$190k/yr OnsiteFull Time
Vorticity
Vorticity: Developing specialized silicon to accelerate scientific computing beyond GPUs.
Bachelor's in math/physics/CS/engineering, strong Python skills, solid foundation in math/physics/CS, ability to work across abstraction levels and disciplines.
Python, CUDA
3d
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Software Development Engineer IV - Algorithms and Scientific Data
Santa Barbara or United States
$119k-$190k/yr HybridFull Time
Bruker
BrukerNASDAQ: BRKR: Manufactures high-performance scientific instruments and analytical diagnostic solutions.
5+ YOE5+ years professional experience in production software or scientific algorithms; 3+ years Windows C#/C++ development; strong signal/image processing, numerical methods or ML; experience with multithreaded systems and algorithm validation.
C++, STL, C#, .NET, WPF, Python, GitHub Copilot, Visual Studio Code, Microsoft Visual Studio, C++/CLI, MFC, GitHub