43 scientist i jobs at 31 companies in Santa Clara, CA
1w
Save
Mark Applied
Hide
Scientist I
South San Francisco, California, United States
$130k-$140k/yr OnsiteFull Time
3+ YOEPh.D. in a relevant life science field, 3+ years of industry or postdoctoral experience, hands-on NGS and molecular biology experience, experimental design, data analysis, and troubleshooting skills.
NGS, Tapestation, qPCR, JMP, R, Python, LIMS, AI
1mo
Save
Mark Applied
Hide
Senior Scientist I, siRNA Therapeutics – Oncology
South San Francisco, California, United States
$97k-$184k/yr OnsiteFull Time
5+ YOEBS/MS/PhD in relevant biological science with substantial hands-on experience in siRNA/RNAi biology, molecular assays, mammalian cell culture and transfection, assay development, data analysis, and strong communication skills.
ELN, RT-qPCR, qPCR, RNA-seq, ELISA, Flow cytometry, Microscopy, Western blot, RNAi, antibody\u0011oligonucleotide conjugates (AOC)
1d
Save
Mark Applied
Hide
Scientist I
South San Francisco, California, United States
$135k-$158k/yr OnsiteFull Time
4+ YOEM.S. with 7+ or Ph.D. with 4+ years of industry experience in preformulation and preclinical formulation; hands-on experience with poorly soluble compounds, HPLC/UPLC, dose verification, and solubility assays.
HPLC, UPLC, mass spectrometry, USP, GLP
1mo
Save
Mark Applied
Hide
Scientist I - III
Fremont, California, United States
OnsiteFull Time, Contract
3+ YOEBS +5 years or MS +3 years in pharmaceutical/biotech development, experience with analytical method development, GMP/GLP laboratory testing, aseptic processing, and strong communication skills.
7h
Save
Mark Applied
Hide
Sr. Scientist I/Sr. Scientist II, Applied AI & Agentic Systems for Drug Discovery
Boston or San Francisco
$160k-$220k/yr HybridFull Time
5+ YOEPhD or equivalent in a quantitative field, 5+ years relevant experience for Scientist I or 8+ for Scientist II, drug discovery contributions, LLM agent development, Python, MLOps, and scientific communication.
Large Language Models (LLM), Model Context Protocol (MCP), LIMS, ELN, MLOps, Python, Claude, GPT, Claude Code, Codex, RDKit, OpenEye, Schrödinger
1mo
Save
Mark Applied
Hide
Senior AI Data Scientist I
Alameda, California, United States
$144k-$203k/yr OnsiteFull Time
5+ YOEDevelop, train, and validate AI/ML models for clinical datasets; proficiency with Python, R, SQL; experience with Databricks and AWS; strong statistical and data engineering skills; documentation and GxP-compliant validation experience.
Python, Pandas, NumPy, scikit-learn, R, SQL, LLM, Databricks, Delta Lake, AWS S3, AWS Lambda, AWS Glue, Git, GitHub, Jira, Spotfire, Tableau, Power BI
2mo
Save
Mark Applied
Hide
Senior Scientist I, Oncology Research
South San Francisco or Emeryville
$155k-$175k/yr HybridFull Time
4+ YOEPhD in immunology/cell biology, 4+ years industry experience, expertise in cell culture, flow cytometry, cytokine analysis and cytotoxicity assays, strong independent scientific judgment, leadership, and communication skills; seminar presentation required.
2mo
Save
Mark Applied
Hide
Staff Scientist I
West Sacramento or Fresno or San Ramon or Marysville
$50k-$60k/yr HybridFull Time
0+ YOEBachelor's in environmental science/engineering, 0–2 years stormwater or SWPPP experience preferred, knowledge of stormwater regulations, inspection/sampling experience, valid driver\u0002s license, ability to travel to project sites.
SMARTS, ArcGIS
1mo
Save
Mark Applied
Hide
Analytical Scientist I
Emeryville, California, United States
$120k-$140k/yr HybridFull Time
1+ YOEPhD (preferred) in relevant field or equivalent industry experience; 1+ years biologics industry experience; assay development and protein characterization (HPLC, LC-MS, charge/aggregation, PTM); GLP method experience; hands-on LC-MS/Agilent QTOF; strong communication.
HPLCs, FPLCs, mass spectrometers, LC-MS, Agilent QTOF, proteomic software, Electronic laboratory instruments
1w
Save
Mark Applied
Hide
Scientist I, Drug Product
Redwood City, California, United States
$119k-$149k/yr OnsiteFull Time
0+ YOEPharmaceutical science, chemistry, chemical engineering, or related degree with relevant pharmaceutical or biotech experience; experience may range from 0–2 years with a Ph.D. or appropriate experience with a bachelor's/master's degree.
ICH
1w
Save
Mark Applied
Hide
Scientist, Biochemistry I or II
Menlo Park, California, United States
$97k-$168k/yr OnsiteFull Time
5+ YOERequires an MSc in a relevant life science discipline, 5+ years in life sciences, 3+ years in recombinant protein production, chromatography and protein characterization experience, and current US work authorization.
AKTA, HPLC, TFF, SDS-PAGE, PLM, ERP, Next-Generation Sequencing
2mo
Save
Mark Applied
Hide
Scientist I - IVD Assay Development
Fremont, California, United States
$120k-$140k/yr OnsiteFull Time
0+ YOEPh.D. or M.S. in biochemistry, molecular biology, immunology or related; 0–2+ years IVD assay development experience; hands-on immunoassay and molecular technique experience; knowledge of FDA 21 CFR Part 820 and ISO 13485; proficiency in data analysis (Excel, GraphPad Prism).
NULISA, GraphPad Prism, Microsoft Excel
6d
Save
Mark Applied
Hide
Senior Scientist I, Antibody Engineering
San Mateo, California, United States
$160k-$185k/yr OnsiteFull Time
5+ YOEPh.D. in a relevant biological science, 5+ years of industry research, protein and antibody engineering expertise, mammalian cell culture, assays, protein characterization, data analysis, and strong communication skills.
machine learning, synthetic biology, AI/ML, agentic software tools
2w
Save
Mark Applied
Hide
Senior Scientist I, Translational Research
Chicago or Boston or Redwood City or New York City
$100k-$160k/yr OnsiteFull Time
4+ YOEPhD in a quantitative or related biological discipline, 4+ years in drug development using genomic and multimodal data, and proficiency in R, Python, and SQL. Experience with clinical, molecular, and omics data required.
R, Python, SQL, Pandas, NumPy, SciPy, Scikit-learn, Jupyter Notebooks, RStudio, tidyverse, ggplot, Git, matplotlib, seaborn, HTML5, CSS3, JavaScript, D3, Plotly, Flask, Dask, Docker, AWS, Artificial Intelligence (AI)
1mo
Save
Mark Applied
Hide
Scientist I/II, Antibody Discovery
Palo Alto, California, United States
$100k-$140k/yr HybridFull Time
2+ YOEPhD (or MS/BS with equivalent experience) in molecular biology/biochemistry or related field, 2+ years industry experience, proficiency in molecular and protein techniques, antibody screening assays, cell culture, immunological assays, data analysis and scientific communication.
CHO, 293T, Protein A, Protein G, SEC, SDS-PAGE, Western blot, ELISA, flow cytometry, SPR, BLI, Gibson assembly, Golden Gate, PCR, microscopy
1w
Save
Mark Applied
Hide
Data Scientist I, Tech
San Francisco, California, United States
$125k-$139k/yr HybridFull Time
Bachelor's degree in a relevant quantitative or technology field; R or Python, SQL, experimentation, statistical analysis, metrics, quantitative modeling, and data visualization skills required.
R, Python, SQL, Tableau, Google Sheets, Microsoft Excel
4w
Save
Mark Applied
Hide
Research Scientist I/II
Brisbane, California, United States
$132k-$167k/yr OnsiteFull Time
8+ YOEPhD or equivalent experience; expert hands-on NGS workflow experience, strong biological knowledge in cfDNA/cancer, experimental design, data analysis, and cross-functional collaboration.
Python, R, ELN, LIMS
6d
Save
Mark Applied
Hide
Principal Bioinformatics Scientist I
Santa Clara, California, United States
$121k-$225k/yr OnsiteFull Time
4+ YOEBachelor's plus 9 years, master's plus 7 years, or Ph.D. plus 4 years of related experience; CAP/CLIA diagnostic validation experience; Python, R, C++, Linux/Bash, Nextflow, and containerization expertise.
Nextflow, Docker, Singularity, Git, Python, R, C++, Linux, Bash
1mo
Save
Mark Applied
Hide
Scientist I, Analytical Development
San Carlos, California, United States
$129k-$151k/yr OnsiteFull Time
Hands-on lab experience performing analytical assays (H/UPLC, LC-MS, CE, ELISA, SDS-PAGE, icIEF, PCR), method development/troubleshooting, strong documentation and data interpretation; PhD/MS/BS in relevant science field required with corresponding industry experience.
HPLC, UPLC, SEC, CE, UV-Vis, ELISA, electrophoresis, plate-based assays, LC-MS, SDS-PAGE, icIEF, Western Blot, PCR
1mo
Save
Mark Applied
Hide
Clinical Lab Scientist I
San Carlos, California, United States
$48-$60/hr OnsiteFull Time
1+ YOEBS/BA in relevant field, California CLS or CGMBS license, 1–2 years clinical lab experience, BSL-2 lab experience, molecular biology skills, strong communication and troubleshooting.
Explore Jobs
Expand Your Job Search
Top Cities Near Santa Clara for Scientist I
- Scientist I jobs in San Jose, CA
- Scientist I jobs in San Francisco, CA
- Scientist I jobs in Oakland, CA
- Scientist I jobs in Fremont, CA
- Scientist I jobs in Hayward, CA
- Scientist I jobs in Salinas, CA
- Scientist I jobs in Sunnyvale, CA
- Scientist I jobs in Concord, CA
- Scientist I jobs in Berkeley, CA
- Scientist I jobs in Antioch, CA
- Scientist I jobs in Richmond, CA
- Scientist I jobs in Daly City, CA
- Scientist I jobs in San Mateo, CA
- Scientist I jobs in San Leandro, CA
- Scientist I jobs in Livermore, CA
- Scientist I jobs in Tracy, CA
- Scientist I jobs in Redwood City, CA
- Scientist I jobs in Mountain View, CA
- Scientist I jobs in Pleasanton, CA
- Scientist I jobs in Alameda, CA